@base . @prefix rdf: . @prefix dc: . @prefix owl: . @prefix rdfs: . @prefix skos: . <> a owl:Ontology, skos:ConceptScheme ; rdfs:label "WikiPathways WP Ontology"@en ; rdfs:seeAlso ; owl:versionIRI . <#Binding> a owl:Class ; rdfs:comment "A binding interaction between two physical entities resulting in the formation of an explicit complex that is reversible without an external factor (e.g. protein complexes)."@en ; rdfs:label "Binding"@en ; rdfs:subClassOf <#DirectedInteraction> ; skos:inScheme <> . <#Catalysis> a owl:Class ; rdfs:comment "A process where a chemical reaction is enhanced by the action of a catalyst."@en ; rdfs:label "Catalysis"@en ; rdfs:subClassOf <#DirectedInteraction> ; skos:inScheme <> . <#Complex> a owl:Class ; rdfs:comment """A physically bound combination of two or more biological entities."""@en ; rdfs:label "Complex"@en ; rdfs:subClassOf <#DataNode> ; skos:inScheme <> . <#ComplexBinding> a owl:Class ; rdfs:comment "A binding interaction that specifically leads to the formation of a complex."@en ; rdfs:label "ComplexBinding"@en ; rdfs:subClassOf <#DirectedInteraction> ; skos:inScheme <> . <#Conversion> a owl:Class ; rdfs:comment """A process in which a biological entity gets converted into another entity. This could be a metabolic conversion where compound gets chemical modified."""@en ; rdfs:label "Conversion"@en ; rdfs:subClassOf <#DirectedInteraction> ; skos:inScheme <> . <#DataNode> a owl:Class ; rdfs:comment "Superclass; deprecated; do not use."@en ; rdfs:label "DataNode"@en ; skos:inScheme <> . <#DirectedInteraction> a owl:Class ; rdfs:comment "Defines a biochemical relationship from a source biological entity to a target biological entity."@en ; rdfs:label "DirectedInteraction"@en ; rdfs:subClassOf <#Interaction> ; skos:inScheme <> . <#GeneProduct> a owl:Class ; rdfs:comment """An entity representing any product of a given gene, including DNA, RNA and Protein. This is the most generic representation of a gene-based biomolecule and is useful when more than one representation might be useful in the given context."""@en ; rdfs:label "GeneProduct"@en ; rdfs:subClassOf <#DataNode> ; skos:inScheme <> . <#Inhibition> a owl:Class ; rdfs:comment "A process in which one biological entity restrains, blocks, or suppresses another biological entity or interaction."@en ; rdfs:label "Inhibition"@en ; rdfs:subClassOf <#DirectedInteraction> ; skos:inScheme <> . <#Interaction> a owl:Class ; rdfs:comment "Defines the biochemical relationship between biological entities."@en ; rdfs:label "Interaction"@en ; skos:inScheme <> . <#Metabolite> a owl:Class ; rdfs:comment """Any chemical compound taking part in a pathway. Unlike true metabolites, this node is also used for compounds which are not the product or substrate of a metabolic conversion."""@en ; rdfs:label "Metabolite"@en ; rdfs:subClassOf <#DataNode> ; skos:inScheme <> . <#Pathway> a owl:Class ; rdfs:comment "A biological process representing a set of interactions and relationships among genes, proteins, metabolites, and other factors in the context of cellular compartments, tissues and organisms."@en ; rdfs:label "Pathway"@en ; skos:inScheme <> . <#Protein> a owl:Class ; rdfs:comment "A biomolecular polymer of amino acids, translated from mRNA."@en ; rdfs:label "Protein"@en ; rdfs:subClassOf <#DataNode> ; skos:inScheme <> . <#PublicationReference> a owl:Class ; rdfs:comment "A reference to a published article, book or other citable material. Most commonly a primary literature reference that is indexed by PubMed."@en ; rdfs:label "PublicationReference"@en ; skos:inScheme <> . <#Rna> a owl:Class ; rdfs:comment "A biomolecular polymer of ribonucleic acids, transcibed from DNA."@en ; rdfs:label "Rna"@en ; rdfs:subClassOf <#DataNode> ; skos:inScheme <> . <#Stimulation> a owl:Class ; rdfs:comment "An interaction in which the source entity enhances the raate or extent of another reaction or entity."@en ; rdfs:label "Stimulation"@en ; rdfs:subClassOf <#DirectedInteraction> ; skos:inScheme <> . <#TranscriptionTranslation> a owl:Class ; rdfs:comment "An interaction in which the source entity regulates or influences in the transcription or translation of a target entity. Also referred to as a Template Reaction."@en ; rdfs:label "Transcription Translation"@en ; rdfs:subClassOf <#DirectedInteraction> ; skos:inScheme <> . <#bdbChEBI> a owl:ObjectProperty ; rdfs:comment "A variable URL to the ChEBI data source."@en ; rdfs:label "BridgeDb ChEBI link"@en ; rdfs:range <#Metabolite>, rdfs:Resource ; skos:inScheme <> . <#bdbChemspider> a owl:ObjectProperty ; rdfs:comment "A variable URL to the Chemspider data source."@en ; rdfs:label "BridgeDb ChemSpider link"@en ; rdfs:range <#Metabolite>, rdfs:Resource ; skos:inScheme <> . <#bdbEnsembl> a owl:ObjectProperty ; rdfs:comment "A variable URL to the Ensembl data source."@en ; rdfs:label "BridgeDb Ensembl link"@en ; rdfs:range rdfs:Resource ; skos:inScheme <> . <#bdbEntrezGene> a owl:ObjectProperty ; rdfs:comment "A variable URL to the NCBI Gene data source."@en ; rdfs:label "BridgeDb Entrez Gene link"@en ; rdfs:range rdfs:Resource ; skos:inScheme <> . <#bdbHgncSymbol> a owl:ObjectProperty ; rdfs:comment "A variable URL to the HUGO Gene Nomenclature Committee (HGNC) data source."@en ; rdfs:label "BridgeDb HGNC link"@en ; rdfs:range rdfs:Resource ; skos:inScheme <> . <#bdbHmdb> a owl:ObjectProperty ; rdfs:comment "A variable URL to the Human Metabolome Database (HMDB) data source."@en ; rdfs:label "BridgeDb HMDB link"@en ; rdfs:range <#Metabolite>, rdfs:Resource ; skos:inScheme <> . <#bdbPubChem> a owl:ObjectProperty ; rdfs:comment "A variable URL to the PubChem data source (Compound identifiers)."@en ; rdfs:label "BridgeDb PubChem link"@en ; rdfs:range <#Metabolite>, rdfs:Resource ; skos:inScheme <> . <#bdbUniprot> a owl:ObjectProperty ; rdfs:comment "A variable URL to the UniProt data source."@en ; rdfs:label "BridgeDb UniProt link"@en ; rdfs:range rdfs:Resource ; skos:inScheme <> . <#celltypeOntologyTag> a owl:ObjectProperty ; rdfs:comment """A term from the Cell Type ontology available on the NCBO's BioPortal (http://bioportal.bioontology.org/ontologies/CL)."""@en ; rdfs:domain ; rdfs:label "cell type ontology tag"@en ; rdfs:range rdfs:Resource ; rdfs:subClassOf <#ontologyTag> ; skos:inScheme <> . <#diseaseOntologyTag> a owl:ObjectProperty ; rdfs:comment "A term from the Human Disease Ontology available on the NCBO's BioPortal (http://bioportal.bioontology.org/ontologies/DOID)."@en ; rdfs:domain ; rdfs:label "disease ontology tag"@en ; rdfs:range rdfs:Resource ; rdfs:subClassOf <#ontologyTag> ; skos:inScheme <> . <#isAbout> a owl:DatatypeProperty ; rdfs:comment "It is the link between the biological entity and the gpml entity. Used in cases of interactions, complexes and groups."@en ; rdfs:label "is about"@en ; skos:inScheme <> . <#ontologyTag> a owl:ObjectProperty ; rdfs:comment "A term from an ontology or controlled vocabulary."@en ; rdfs:domain ; rdfs:label "ontology tag"@en ; rdfs:range ; skos:inScheme <> . <#organism> a owl:DatatypeProperty ; rdfs:comment "The scientific name (e.g., Homo sapiens) of the species being described by the pathway."@en ; rdfs:domain ; rdfs:label "organism"@en ; rdfs:range rdfs:Class ; skos:inScheme <> . <#organismName> a owl:DatatypeProperty ; rdfs:comment "Latin name of the organsm in which this pathway takes place."@en ; rdfs:domain ; rdfs:label "organism name"@en ; rdfs:range ; skos:inScheme <> . <#participants> a owl:ObjectProperty ; rdfs:label "participants"@en ; skos:inScheme <> . <#pathwayOntologyTag> a owl:ObjectProperty ; rdfs:comment "A term from the Pathway Ontology ontology available at NCBO's BioPortal (http://bioportal.bioontology.org/ontologies/PW)."@en ; rdfs:domain ; rdfs:label "pathway ontology tag"@en ; rdfs:range rdfs:Resource ; rdfs:subClassOf <#ontologyTag> ; skos:inScheme <> . <#source> a owl:ObjectProperty ; rdfs:comment "The beginning terminus of an interaction."@en ; rdfs:domain <#DirectedInteraction> ; rdfs:label "source"@en ; rdfs:range <#DataNode> ; rdfs:subClassOf <#participants> ; skos:inScheme <> . <#target> a owl:ObjectProperty ; rdfs:comment "The ending terminus of an interaction."@en ; rdfs:domain <#DirectedInteraction> ; rdfs:label "target"@en ; rdfs:subClassOf <#participants> ; skos:inScheme <> . dc:contributor "Alexander Pico"@en, "Andra Waagmeester"@en, "Anwesha Bohler"@en, "Egon Willighagen"@en, "Martina Kutmon"@en, "Ryan Miller"@en, "Susan Coort"@en ; a owl:Ontology . rdfs:subClassOf <#GeneProduct> . rdfs:subClassOf <#GeneProduct> . rdfs:subClassOf <#GeneProduct> . rdfs:subClassOf <#GeneProduct> . rdfs:subPropertyOf <#organism> .