@prefix rdf: . @prefix : . @prefix obo: . @prefix owl: . @prefix xml: . @prefix xsd: . @prefix rdfs: . @prefix oboInOwl: . obo:IAO_0000115 a owl:AnnotationProperty ; rdfs:label "definition"^^xsd:string . obo:IAO_0000231 a owl:AnnotationProperty . obo:IAO_0100001 a owl:AnnotationProperty . obo:MPATH_0 obo:IAO_0000115 "Pathological structure or process"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:0"^^xsd:string ; a owl:Class ; rdfs:label "pathological entity"^^xsd:string ; rdfs:subClassOf obo:MPATH_1000 . obo:MPATH_1 obo:IAO_0000115 "The sum of morphological and functional disturbances induced by cell and tissue damage, either from intrinsic gene dysfunction or as a result of external factors."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:1"^^xsd:string ; a owl:Class ; rdfs:label "cell and tissue damage"^^xsd:string ; rdfs:subClassOf obo:MPATH_603 . obo:MPATH_10 obo:IAO_0000115 "Extensive necrosis from whatever cause, often following chronic ischemia."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Mortification"^^xsd:string ; oboInOwl:id "MPATH:10"^^xsd:string ; a owl:Class ; rdfs:label "gangrene"^^xsd:string ; rdfs:subClassOf obo:MPATH_4 . obo:MPATH_100 obo:IAO_0000115 "Defect in placental growth, differentiation of circulation; maternal or embryonic component."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:100"^^xsd:string ; a owl:Class ; rdfs:label "placental abnormality"^^xsd:string ; rdfs:subClassOf obo:MPATH_86 . obo:MPATH_1000 obo:IAO_0000115 "Phenotypic observation of the presence or absence of a pathological entity."^^xsd:string ; oboInOwl:created_by "Luke Slater"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:1000"^^xsd:string ; a owl:Class ; rdfs:label "pathological phenotype observation"^^xsd:string . obo:MPATH_101 obo:IAO_0000115 "Lack of, displacement of, or abnormality in function or growth of the glycogen cells."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:101"^^xsd:string ; a owl:Class ; rdfs:label "glycogen cell defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_100 . obo:MPATH_102 obo:IAO_0000115 "Defect in size, cellular composition, function or organisation of the labyrinthine zone of the placenta."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:102"^^xsd:string ; a owl:Class ; rdfs:label "labyrinth zone defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_100 . obo:MPATH_103 obo:IAO_0000115 "Any defect in the maternal or embryonic placental circulation."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:103"^^xsd:string ; a owl:Class ; rdfs:label "placental vascular defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_100 . obo:MPATH_104 obo:IAO_0000115 "Defect in size, cellular composition, function or organisation of the spongiotrophoblast zone of the placenta."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:104"^^xsd:string ; a owl:Class ; rdfs:label "spongiotrophoblast defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_100 . obo:MPATH_105 obo:IAO_0000115 "Lesions leading to or consequent on failure of, or atypical movement of, blood throughout the body."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:105"^^xsd:string ; a owl:Class ; rdfs:label "circulatory disorder"^^xsd:string ; rdfs:subClassOf obo:MPATH_603 . obo:MPATH_106 obo:IAO_0000115 "Abnormal accumulation of fluid; blood or lymph."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:106"^^xsd:string ; a owl:Class ; rdfs:label "fluid accumulation"^^xsd:string ; rdfs:subClassOf obo:MPATH_105 . obo:MPATH_107 obo:IAO_0000115 "Presence of an abnormal amount of fluid (but especially of blood) in the vessels or passages of a part or organ."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:107"^^xsd:string ; a owl:Class ; rdfs:label "congestion"^^xsd:string ; rdfs:subClassOf obo:MPATH_106 . obo:MPATH_108 obo:IAO_0000115 "A syndrome consequent to uncontrolled activation of blood clotting factors leading to disseminated platelet lysis, and fibrin deposition, ultimately leading to bleeding and necrosis as a consequence of inhibition of fibrin polymerisation by degradation products."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "DIC"^^xsd:string ; oboInOwl:id "MPATH:108"^^xsd:string ; a owl:Class ; rdfs:comment "Diagnosed by microthrombi in many organs."^^xsd:string ; rdfs:label "disseminated intravascular coagulation"^^xsd:string ; rdfs:subClassOf obo:MPATH_105 . obo:MPATH_109 obo:IAO_0000115 "An accumulation of an excessive amount of watery fluid in cells or intercellular tissues."^^xsd:string ; oboInOwl:hasExactSynonym "oedema"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:109"^^xsd:string ; a owl:Class ; rdfs:label "edema"^^xsd:string ; rdfs:subClassOf obo:MPATH_106 . obo:MPATH_11 obo:IAO_0000115 "Necrosis associated with local hemorrhage."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:11"^^xsd:string ; a owl:Class ; rdfs:label "hemorrhagic necrosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_4 . obo:MPATH_110 obo:IAO_0000115 "A plug formed from a variety of materials occluding a vessel or tube."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:110"^^xsd:string ; a owl:Class ; rdfs:label "embolus"^^xsd:string ; rdfs:subClassOf obo:MPATH_105 . obo:MPATH_111 obo:IAO_0000115 "An bubble of air occluding flow through a blood or lymphatic vessel."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:111"^^xsd:string ; a owl:Class ; rdfs:label "air embolism"^^xsd:string ; rdfs:subClassOf obo:MPATH_110 . obo:MPATH_112 obo:IAO_0000115 "Occlusion of vessels caused by entry of amniotic fluid, cell and debris into the maternal circulation."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:112"^^xsd:string ; a owl:Class ; rdfs:label "amniotic fluid embolism"^^xsd:string ; rdfs:subClassOf obo:MPATH_110 . obo:MPATH_113 obo:IAO_0000115 "Occlusion of the outflow tract of the right atrium by a thrombus."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:113"^^xsd:string ; a owl:Class ; rdfs:label "atrial embolism"^^xsd:string ; rdfs:subClassOf obo:MPATH_110 . obo:MPATH_114 obo:IAO_0000115 "Occlusion of vessels caused by entry of bone marrow, often fatty debris into the circulation. Usually following trauma."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:114"^^xsd:string ; a owl:Class ; rdfs:label "bone marrow embolism"^^xsd:string ; rdfs:subClassOf obo:MPATH_110 . obo:MPATH_115 obo:IAO_0000115 "Occlusion of vessels caused by entry of lipid or fatty cells into the circulation. Usually following trauma."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:115"^^xsd:string ; a owl:Class ; rdfs:label "fat embolism"^^xsd:string ; rdfs:subClassOf obo:MPATH_110 . obo:MPATH_116 obo:IAO_0000115 "Occlusion of pulmonary vessels by an embolus."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:116"^^xsd:string ; a owl:Class ; rdfs:label "pulmonary embolism"^^xsd:string ; rdfs:subClassOf obo:MPATH_110 . obo:MPATH_117 obo:IAO_0000115 "Occlusion of vessels, usually small arterioles in the dermis by various emboli."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:117"^^xsd:string ; a owl:Class ; rdfs:label "skin embolism"^^xsd:string ; rdfs:subClassOf obo:MPATH_110 . obo:MPATH_118 obo:IAO_0000115 "Production of systemic vessel occlusion by emboli released from the left side of the heart, or the aorta."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:118"^^xsd:string ; a owl:Class ; rdfs:label "systemic embolism"^^xsd:string ; rdfs:subClassOf obo:MPATH_110 . obo:MPATH_119 obo:IAO_0000115 "Abnormal release of whole blood or the cellular component from the circulation."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:119"^^xsd:string ; a owl:Class ; rdfs:label "hemorrhage and non-specified extravasation"^^xsd:string ; rdfs:subClassOf obo:MPATH_105 . obo:MPATH_12 obo:IAO_0000115 "Soft or fluid tissue remains of a circumscribed area of necrosis digested by proteolytic enzymes."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:12"^^xsd:string ; a owl:Class ; rdfs:label "liquefactive necrosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_4 . obo:MPATH_120 obo:IAO_0000115 "A red/purple patch caused by extravasation of blood into the skin. Larger than petechiae."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:120"^^xsd:string ; a owl:Class ; rdfs:comment "May also be used for any organ, although more generally used with respect to the skin."^^xsd:string ; rdfs:label "ecchymosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_119 . obo:MPATH_121 obo:IAO_0000115 "A localised deposition of clotted or partially clotted extravasated blood."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Bruise"^^xsd:string ; oboInOwl:id "MPATH:121"^^xsd:string ; a owl:Class ; rdfs:label "hematoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_119 . obo:MPATH_122 obo:IAO_0000115 "Small hemorrhagic spots in the skin caused by blood vessel breakdown."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:122"^^xsd:string ; a owl:Class ; rdfs:comment "Usually used with reference to the skin but can be used in the context of other organs."^^xsd:string ; rdfs:label "petechia"^^xsd:string ; rdfs:subClassOf obo:MPATH_119 . obo:MPATH_123 obo:IAO_0000115 "Purple and variously colored lesions caused by extensive haemorrhage into the skin through ecchymoses/petechia."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:123"^^xsd:string ; a owl:Class ; rdfs:label "purpura"^^xsd:string ; rdfs:subClassOf obo:MPATH_119 . obo:MPATH_124 obo:IAO_0000115 "An area of necrosis resulting from a sudden cessation of arterial or venous blood supply."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:124"^^xsd:string ; a owl:Class ; rdfs:label "infarct"^^xsd:string ; rdfs:subClassOf obo:MPATH_105 . obo:MPATH_125 obo:IAO_0000115 "Presence of an occluding or mural thrombus in a blood vessel."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:125"^^xsd:string ; a owl:Class ; rdfs:label "thrombosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_105 . obo:MPATH_126 obo:IAO_0000115 "Defects in growth (changes in proliferation or mass) and differentiation of cells tissues or organs."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:126"^^xsd:string ; a owl:Class ; rdfs:label "growth and differentiation defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_603 . obo:MPATH_127 obo:IAO_0000115 "A reduction in size of organs or tissues as a result of cell death, loss of cellularity of whatever cause, reduced cellular proliferation or decreased cellular volume."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:127"^^xsd:string ; a owl:Class ; rdfs:label "atrophy"^^xsd:string ; rdfs:subClassOf obo:MPATH_604 . obo:MPATH_128 obo:IAO_0000115 "Non-invasive changes characterized by alteration in the size, shape and organization of the cellular components of an epithelial tissue. Do not confuse with developmental dysplasia MPATH:64."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "intra-epithelial lesion"^^xsd:string ; oboInOwl:id "MPATH:128"^^xsd:string ; a owl:Class ; rdfs:comment "This term has been previously used as a synonym for pre-malignant dysplasia or carcinoma in situ and is now to be preferred."^^xsd:string ; rdfs:label "intra-epithelial neoplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_556 . obo:MPATH_129 obo:IAO_0000115 "epithelial dysplasia"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:129"^^xsd:string ; a owl:Class ; rdfs:comment "obsolete due to renaming of preneoplastic dysplasias and Intraepithelial neoplasias Use MPATH:128."^^xsd:string ; rdfs:label "epithelial dysplasia"^^xsd:string ; owl:deprecated true . obo:MPATH_13 obo:IAO_0000115 "Sensu; hepaticobiliary system. Loss and degeneration of hepatocytes at the portal-lobular interface producing a moth-eaten irregular appearance. Piecemeal necrosis is associated with a lymphocytic infiltrate."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:13"^^xsd:string ; a owl:Class ; rdfs:label "piecemeal necrosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_4 . obo:MPATH_130 obo:IAO_0000115 "Mild non-invasive changes in cell morphology and tissue architecture confined to the epithelium alone."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "IENI"^^xsd:string, "low grade intraepithelial lesion"^^xsd:string, "mild epithelial dysplasia."^^xsd:string ; oboInOwl:id "MPATH:130"^^xsd:string ; a owl:Class ; rdfs:label "mild intra-epithelial neoplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_128 . obo:MPATH_131 obo:IAO_0000115 "Moderate non-invasive changes in cell morphology and tissue architecture confined to the epithelium alone."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "IENII"^^xsd:string, "high grade intraepithelial lesion"^^xsd:string, "moderate epithelial dysplasia"^^xsd:string ; oboInOwl:id "MPATH:131"^^xsd:string ; a owl:Class ; rdfs:label "moderate intra-epithelial epithelial neoplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_128 . obo:MPATH_132 obo:IAO_0000115 "Severe non-invasive malignancy associated changes in cell morphology and tissue architecture confined to the epithelium alone."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "IENIII"^^xsd:string, "carcinoma in situ"^^xsd:string, "high grade intra-epithelial lesion"^^xsd:string, "severe epithelial dysplasia"^^xsd:string ; oboInOwl:id "MPATH:132"^^xsd:string ; a owl:Class ; rdfs:comment "Carcinoma in situ may be used in some systems as a synonym."^^xsd:string ; rdfs:label "severe intra-epithelial neoplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_128 . obo:MPATH_133 obo:IAO_0000115 "Small organ or structure; failure to develop to normal size."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Developmental hypoplasia"^^xsd:string ; oboInOwl:id "MPATH:133"^^xsd:string ; a owl:Class ; rdfs:label "hypoplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_604 . obo:MPATH_134 obo:IAO_0000115 "An increase in cell numbers in comparison to normal as a consequence of increased cell proliferation. Non -neoplastic process."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:134"^^xsd:string ; a owl:Class ; rdfs:label "hyperplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_604 . obo:MPATH_135 obo:IAO_0000115 "Abnormal proliferation of epithelial and stromal cells."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:135"^^xsd:string ; a owl:Class ; rdfs:label "epithelial and stromal hyperplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_602 . obo:MPATH_136 obo:IAO_0000115 "A polypoid outgrowth of both epidermis and dermal fibrovascular tissue."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "skin tag"^^xsd:string ; oboInOwl:id "MPATH:136"^^xsd:string ; a owl:Class ; rdfs:label "fibroepithelial polyp"^^xsd:string ; rdfs:subClassOf obo:MPATH_138 . obo:MPATH_137 obo:IAO_0000115 "Benign proliferation of glandular epithelium accompanied by proliferation of fibroblastic stroma."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:137"^^xsd:string ; a owl:Class ; rdfs:label "fibroglandular hyperplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_135 . obo:MPATH_138 obo:IAO_0000115 "Abnormal proliferation of epithelial cells and epithelial components."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:138"^^xsd:string ; a owl:Class ; rdfs:label "epithelial hyperplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_602 . obo:MPATH_139 obo:IAO_0000115 "Benign proliferation of goblet cells."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:139"^^xsd:string ; a owl:Class ; rdfs:label "goblet cell hyperplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_138 . obo:MPATH_14 obo:IAO_0000115 "A pathological process of loss or degradation of function, or structural integrity, of a tissue, organ or cell."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:14"^^xsd:string ; a owl:Class ; rdfs:label "process of degenerative change"^^xsd:string ; rdfs:subClassOf obo:MPATH_597 . obo:MPATH_140 obo:IAO_0000115 "A benign polyp, usually in the colon, showing hyperplasia."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:140"^^xsd:string ; a owl:Class ; rdfs:label "hyperplastic polyp"^^xsd:string ; rdfs:subClassOf obo:MPATH_491 . obo:MPATH_141 obo:IAO_0000115 "A projecting mass of granulation tissue which may become covered by regenerating epithelium."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "pseudopolyp"^^xsd:string ; oboInOwl:id "MPATH:141"^^xsd:string ; a owl:Class ; rdfs:label "inflammatory polyp"^^xsd:string ; rdfs:subClassOf obo:MPATH_491 . obo:MPATH_142 obo:IAO_0000115 "Benign hyperplasia of the ducts of the mammary gland. Ducts exhibit more than the usual two layer epithelium (inner cuboidal to columnar cells; outer layer of myoepithelium) without cytological atypia."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:142"^^xsd:string ; a owl:Class ; rdfs:label "intraductal hyperplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_138 . obo:MPATH_143 obo:IAO_0000115 "Benign proliferation of glandular epithelia, eg. Endocervical glands. Consists of tightly packed glandular or tubular units, which vary in size, lined by a flattened-to-cuboidal epithelium."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "microglandular adenosis"^^xsd:string ; oboInOwl:id "MPATH:143"^^xsd:string ; a owl:Class ; rdfs:label "microglandular hyperplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_138 . obo:MPATH_144 obo:IAO_0000115 "Benign proliferation of glandular myoepithelial cells."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:144"^^xsd:string ; a owl:Class ; rdfs:label "myoepithelial hyperplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_138 . obo:MPATH_145 obo:IAO_0000115 "Benign proliferation of adipose tissue."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:145"^^xsd:string ; a owl:Class ; rdfs:label "fat cell hyperplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_602 . obo:MPATH_146 obo:IAO_0000231 obo:IAO_0000227 ; obo:IAO_0100001 obo:MPATH_652 ; a owl:Class ; owl:deprecated true . obo:MPATH_147 obo:IAO_0000115 "Benign enlargement of lymphoid tissues."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "lymphoid hypertrophy"^^xsd:string ; oboInOwl:id "MPATH:147"^^xsd:string ; a owl:Class ; rdfs:label "lymphoid hyperplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_602 . obo:MPATH_148 obo:IAO_0000115 "Benign proliferation of mesothelial cells lining body cavities presenting as small solid cell clusters or multiple layers with columnar morphology and delicate eosinophilic cytoplasm."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "mesothelioma"^^xsd:string ; oboInOwl:id "MPATH:148"^^xsd:string ; a owl:Class ; rdfs:label "mesothelial hyperplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_602 . obo:MPATH_149 obo:IAO_0000115 "Benign proliferation of epidermal cells with hyperkeratosis. Variable growth pattern, regular to papillary (exophytic squamous cell hyperplasia)."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "epidermal hyperplasia."^^xsd:string, "squamous cell hyperplasia"^^xsd:string ; oboInOwl:id "MPATH:149"^^xsd:string ; a owl:Class ; rdfs:label "squamous hyperplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_602 . obo:MPATH_15 obo:IAO_0000115 "Change of tissue to a lower state of integrity or less functional form, as in heart failure."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:15"^^xsd:string ; a owl:Class ; rdfs:label "general degenerative process"^^xsd:string ; rdfs:subClassOf obo:MPATH_14 . obo:MPATH_150 obo:IAO_0000115 "Hyperplasia of the Malpighian layer (prickle cell) of the epidermis."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:150"^^xsd:string ; a owl:Class ; rdfs:label "acanthosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_149 . obo:MPATH_151 obo:IAO_0000115 "Discrete, flat or elevated, verrucous, keratotic lesions. Epidermal changes are characterized by acanthosis, parakeratosis, and dyskeratoses. Dysplastic change is present and the keratinocytes vary in size and shape. Associated with UV exposure in humans. Not defined in mice to date."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:151"^^xsd:string ; a owl:Class ; rdfs:label "actinic keratosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_149, obo:MPATH_556 . obo:MPATH_152 obo:IAO_0000115 "Benign proliferation of the basal layer cells of the skin."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:152"^^xsd:string ; a owl:Class ; rdfs:label "basal cell hyperplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_149 . obo:MPATH_153 obo:IAO_0000115 "Increased thickness of the granular layer of a stratified squamous epithelium, associated with hyperorthokeratosis."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:153"^^xsd:string ; a owl:Class ; rdfs:label "hypergranulosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_149 . obo:MPATH_154 obo:IAO_0000115 "Thickening of the surface layers (stratum corneum) in the skin or other stratified squamous epithelium. Cf. ortho- and para-keratosis."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "cornification"^^xsd:string, "hyperorthokeratosis"^^xsd:string, "hyperparakeratosis"^^xsd:string ; oboInOwl:id "MPATH:154"^^xsd:string ; a owl:Class ; rdfs:label "hyperkeratosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_149 . obo:MPATH_155 obo:IAO_0000115 "Thickening of the anuclear cell layer limited to the stratum corneum, as in a stratified squamous epithelium."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:155"^^xsd:string ; a owl:Class ; rdfs:label "orthokeratosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_154 . obo:MPATH_156 obo:IAO_0000115 "Thickening of the surface cell layer of a stratified squamous epithelium with retention of nuclei in the cells of the stratum corneum."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:156"^^xsd:string ; a owl:Class ; rdfs:label "parakeratosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_154 . obo:MPATH_157 obo:IAO_0000115 "Benign hyperplasia and down-growth of epidermal cells. Microscopically resembling well-differentiated squamous cell carcinoma."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "pseudocarcinoma"^^xsd:string, "pseudocarcinomatous hyperplasia"^^xsd:string, "pseudoepitheliomatous hyperplasia"^^xsd:string ; oboInOwl:id "MPATH:157"^^xsd:string ; a owl:Class ; rdfs:label "pseudoepithelioma/pseudocarcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_149 . obo:MPATH_158 obo:IAO_0000115 "Superficial, benign, verrucous, often pigmented, greasy lesions consisting of proliferating epidermal cells, resembling basal cells, enclosing cornifying cysts."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Basal cell papilloma"^^xsd:string, "seborrheic verruca"^^xsd:string ; oboInOwl:id "MPATH:158"^^xsd:string ; a owl:Class ; rdfs:label "seborrheic keratosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_149 . obo:MPATH_159 obo:IAO_0000115 "Increase in size or mass of a cell, tissue or organ without increase in cell proliferation. Cf. Hyperplasia MPATH: 133."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:159"^^xsd:string ; a owl:Class ; rdfs:label "hypertrophy"^^xsd:string ; rdfs:subClassOf obo:MPATH_604 . obo:MPATH_16 obo:IAO_0000115 "A conversion of the connective tissues into a gelatinous or mucous substance."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Mucoid degeneration"^^xsd:string, "myxomatosis"^^xsd:string ; oboInOwl:id "MPATH:16"^^xsd:string ; a owl:Class ; rdfs:label "myxoid/myxomatous degeneration"^^xsd:string ; rdfs:subClassOf obo:MPATH_15 . obo:MPATH_160 obo:IAO_0000115 "Abnormal transformation of an fully differentiated adult cell or tissue of one kind into a differentiated tissue of another kind. An adult instance of developmental transdifferentiation MPATH:85 Traditionally defined as a form of abnormal regeneration in which a type of cell different from that found normally in a given location is produced."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:160"^^xsd:string ; a owl:Class ; rdfs:label "metaplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_604 . obo:MPATH_161 obo:IAO_0000115 "Metaplasia resulting in heterotopic formation of cartilage."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:161"^^xsd:string ; a owl:Class ; rdfs:label "cartilaginous metaplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_605 . obo:MPATH_162 obo:IAO_0000115 "Metaplasia occurring within epithelia."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:162"^^xsd:string ; a owl:Class ; rdfs:label "epithelial metaplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_605 . obo:MPATH_163 obo:IAO_0000115 "Alteration of acinar epithelium of, for example, mammary tissue to resemble apocrine glands."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:163"^^xsd:string ; a owl:Class ; rdfs:label "apocrine metaplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_162 . obo:MPATH_164 obo:IAO_0000115 "Appearance of heterotopic gastric epithelium."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:164"^^xsd:string ; a owl:Class ; rdfs:label "gastric metaplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_162 . obo:MPATH_165 obo:IAO_0000115 "Development of heterotopic glandular epithelia."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:165"^^xsd:string ; a owl:Class ; rdfs:label "glandular metaplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_162 . obo:MPATH_166 obo:IAO_0000115 "Metaplasia resulting in formation of mucus secreting goblet cells."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:166"^^xsd:string ; a owl:Class ; rdfs:label "goblet cell metaplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_162 . obo:MPATH_167 obo:IAO_0000115 "Appearance of heterotopic intestinal epithelium."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:167"^^xsd:string ; a owl:Class ; rdfs:label "intestinal metaplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_162 . obo:MPATH_168 obo:IAO_0000115 "Metaplasia resulting in formation of fat cells."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:168"^^xsd:string ; a owl:Class ; rdfs:label "lipomatous metaplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_605 . obo:MPATH_169 obo:IAO_0000115 ".A rare benign neoplasm of the mucosa of the urinary bladder or the urethra, consisting of tubular structures resembling those of the nephron."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "nephrogenic adenoma"^^xsd:string ; oboInOwl:id "MPATH:169"^^xsd:string ; a owl:Class ; rdfs:label "nephrogenic metaplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_162 . obo:MPATH_17 obo:IAO_0000115 "Defect of a subcellular structure or organelle."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:17"^^xsd:string ; a owl:Class ; rdfs:label "subcellular defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_1 . obo:MPATH_170 obo:IAO_0000115 "Appearance of oncocytic cells in for example an epithelium or tumor."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:170"^^xsd:string ; a owl:Class ; rdfs:comment "An oncocyte is an acidophilic cell containing numerous mitochondria - an oxophil cell."^^xsd:string ; rdfs:label "oncocytic metaplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_162 . obo:MPATH_171 obo:IAO_0000115 "Change of a glandular or mucosal epithelium into squamous epithelium."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:171"^^xsd:string ; a owl:Class ; rdfs:label "squamous metaplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_162 . obo:MPATH_172 obo:IAO_0000115 "Metaplastic response of the transitional epithelium, for example in the bladder to give squamous metaplasia and glandular metaplasia for example."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:172"^^xsd:string ; a owl:Class ; rdfs:label "transitional cell metaplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_162 . obo:MPATH_173 obo:IAO_0000115 "A progressive disease of the bone marrow where neoplastic bone marrow stem cells lodge and grow at sites outside the bone marrow."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:173"^^xsd:string ; a owl:Class ; rdfs:label "myeloid metaplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_512 . obo:MPATH_174 obo:IAO_0000115 "Metaplasia resulting in formation of bone."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasBroadSynonym "ectopic bone"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:174"^^xsd:string ; a owl:Class ; rdfs:label "osseous metaplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_605 . obo:MPATH_175 obo:IAO_0000115 "The process, normal or abnormal, of damage repair or wound closure."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:175"^^xsd:string ; a owl:Class ; rdfs:label "healing and repair process"^^xsd:string ; rdfs:subClassOf obo:MPATH_596 . obo:MPATH_176 obo:IAO_0000115 "Replacement of connective tissue by fibro-fatty deposits and scar tissue."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:176"^^xsd:string ; a owl:Class ; rdfs:label "connective tissue replacement"^^xsd:string ; rdfs:subClassOf obo:MPATH_175 . obo:MPATH_177 obo:IAO_0000115 "Aberrant process of blood vessel formation and the subsequent remodeling process; does not refer to the initial establishment of the vascular network by vasculogenesis."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "neovascularisation"^^xsd:string ; oboInOwl:id "MPATH:177"^^xsd:string ; a owl:Class ; rdfs:label "angiogenesis"^^xsd:string ; rdfs:subClassOf obo:MPATH_176 . obo:MPATH_178 obo:IAO_0000115 "Abnormal deposition of extracellular matrix proteins or other components."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:178"^^xsd:string ; a owl:Class ; rdfs:label "extracellular matrix deposition"^^xsd:string ; rdfs:subClassOf obo:MPATH_176 . obo:MPATH_179 obo:IAO_0000115 "Deposition of fibrin."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:179"^^xsd:string ; a owl:Class ; rdfs:label "fibrin deposition"^^xsd:string ; rdfs:subClassOf obo:MPATH_176 . obo:MPATH_18 obo:IAO_0000115 "Defect in the structure or function of the cytoskeleton."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:18"^^xsd:string ; a owl:Class ; rdfs:label "cytoskeletal defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_17 . obo:MPATH_180 obo:IAO_0000115 "Abnormal or reactive proliferation of fibroblasts."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:180"^^xsd:string ; a owl:Class ; rdfs:label "fibroblast proliferation"^^xsd:string ; rdfs:subClassOf obo:MPATH_176 . obo:MPATH_181 obo:IAO_0000115 "Reactive formation of fibrous tissue."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:181"^^xsd:string ; a owl:Class ; rdfs:label "fibrosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_176 . obo:MPATH_182 obo:IAO_0000115 "Proliferation of astrocytes in an area of damage in the brain or spinal cord."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:182"^^xsd:string ; a owl:Class ; rdfs:label "gliosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_176 . obo:MPATH_183 obo:IAO_0000115 "Newly formed connective (vascular or fibrous)tissue caused by inflammation or healing (repair) processes. Microscopically consists of capillaries fibroblastic cells and inflammatory cells."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:183"^^xsd:string ; a owl:Class ; rdfs:label "granulation tissue"^^xsd:string ; rdfs:subClassOf obo:MPATH_607 . obo:MPATH_184 obo:IAO_0000115 "Any pathological thickening or hardening of a tissue."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Induration"^^xsd:string ; oboInOwl:id "MPATH:184"^^xsd:string ; a owl:Class ; rdfs:label "sclerosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_176 . obo:MPATH_185 obo:IAO_0000115 "Post-injury regeneration of the functional tissue parenchyma. Eg. Liver."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:185"^^xsd:string ; a owl:Class ; rdfs:label "parenchymal regeneration"^^xsd:string ; rdfs:subClassOf obo:MPATH_175 . obo:MPATH_186 obo:IAO_0000115 "Complete healing through parenchymal regeneration - no fibrosis."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:186"^^xsd:string ; a owl:Class ; rdfs:label "complete parenchymal regeneration"^^xsd:string ; rdfs:subClassOf obo:MPATH_185 . obo:MPATH_187 obo:IAO_0000115 "Incomplete healing usually accompanied by fibrosis."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:187"^^xsd:string ; a owl:Class ; rdfs:label "incomplete parenchymal regeneration"^^xsd:string ; rdfs:subClassOf obo:MPATH_185 . obo:MPATH_188 obo:IAO_0000115 "Inappropriate or aberrant activation or suppression of the immune or inflammatory response."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:188"^^xsd:string ; a owl:Class ; rdfs:label "immunopathological process"^^xsd:string ; rdfs:subClassOf obo:MPATH_596 . obo:MPATH_189 obo:IAO_0000115 "Immune response resulting in tissue injury."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:189"^^xsd:string ; a owl:Class ; rdfs:label "hypersensitivity disease"^^xsd:string ; rdfs:subClassOf obo:MPATH_188 . obo:MPATH_19 obo:IAO_0000115 "Defect in the structure or function of the endoplasmic reticulum."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:19"^^xsd:string ; a owl:Class ; rdfs:label "endoplasmic reticulum defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_17 . obo:MPATH_190 obo:IAO_0000115 "This is manifested by localized or generalized reaction that occurs immediately (minutes) after exposure to an antigen to which the person/animal was previously sensitized. It is IgE-mediated, and mast cell activation and degranulation are hallmarks."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:190"^^xsd:string ; a owl:Class ; rdfs:label "type I hypersensitivity"^^xsd:string ; rdfs:subClassOf obo:MPATH_189 . obo:MPATH_191 obo:IAO_0000115 "Caused by an antibody/antigen reaction: antibodies are directly or indirectly cytotoxic to antigens on cell surfaces or in connective tissues."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:191"^^xsd:string ; a owl:Class ; rdfs:comment "Most often involves IgG and IgM. Complement activation is usually involved."^^xsd:string ; rdfs:label "type II hypersensitivity"^^xsd:string ; rdfs:subClassOf obo:MPATH_189 . obo:MPATH_192 obo:IAO_0000115 "Tissue injury mediated by immune complexes. Generally involves immune complexes formed in the blood via antibodies encountering circulating antigens. Immune complexes then deposit in tissues (especially blood vessels and glomeruli), induce complement activation, and result in tissue injury."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:192"^^xsd:string ; a owl:Class ; rdfs:label "type III hypersensitivity"^^xsd:string ; rdfs:subClassOf obo:MPATH_189 . obo:MPATH_193 obo:IAO_0000115 "An antigen-elicited cellular immune reaction that results in tissue damage, but does not require Ab participation. The response is seen at the area of contact."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:193"^^xsd:string ; a owl:Class ; rdfs:label "type IV hypersensitivity"^^xsd:string ; rdfs:subClassOf obo:MPATH_189 . obo:MPATH_194 obo:IAO_0000115 "Tissue response to inappropriate immune/inflammatory process."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:194"^^xsd:string ; a owl:Class ; rdfs:label "immune mediated disease"^^xsd:string ; rdfs:subClassOf obo:MPATH_188 . obo:MPATH_195 obo:IAO_0000115 "Inflammation of a joint."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:195"^^xsd:string ; a owl:Class ; rdfs:label "arthritis"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_196 obo:IAO_0000115 "Inflammation of the skin."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:196"^^xsd:string ; a owl:Class ; rdfs:label "dermatitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_197 obo:IAO_0000115 "Renal disease characterised by diffuse inflammatory changes in glomeruli not in response to an infectious agent or treatment."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:197"^^xsd:string ; a owl:Class ; rdfs:label "glomerulonephritis"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_198 obo:IAO_0000115 "An anemic/erythrocytopenic condition resulting from an increased rate of immune mediated erythrocyte destruction."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:198"^^xsd:string ; a owl:Class ; rdfs:label "immune mediated hemolytic anaemia"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_199 obo:IAO_0000115 "A condition resulting from an increased rate of immune mediated platelet destruction."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:199"^^xsd:string ; a owl:Class ; rdfs:label "immune mediated thrombocytopenia"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_2 obo:IAO_0000115 "Complete and irreversible cessation of metabolic activity."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:2"^^xsd:string ; a owl:Class ; rdfs:label "cell death"^^xsd:string ; rdfs:subClassOf obo:MPATH_597 . obo:MPATH_20 obo:IAO_0000115 "Defect in the structure or function of the golgi apparatus."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:20"^^xsd:string ; a owl:Class ; rdfs:label "golgi defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_17 . obo:MPATH_200 obo:IAO_0000115 "Inflammation of a muscle."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Initis"^^xsd:string ; oboInOwl:id "MPATH:200"^^xsd:string ; a owl:Class ; rdfs:label "myositis"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_201 obo:IAO_0000115 "Inflammation of a blood vessel."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "angiitis"^^xsd:string, "arteritis"^^xsd:string, "lymphangiitis"^^xsd:string, "phlebitis"^^xsd:string ; oboInOwl:id "MPATH:201"^^xsd:string ; a owl:Class ; rdfs:label "vasculitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_202 obo:IAO_0000115 "Defective immune response; can be primary due to defect in immune system or secondary/acquired due to disease."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:202"^^xsd:string ; a owl:Class ; rdfs:label "immunodeficiency disease"^^xsd:string ; rdfs:subClassOf obo:MPATH_188 . obo:MPATH_203 obo:IAO_0000115 "general immunodeficiency disease"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:203"^^xsd:string ; a owl:Class ; rdfs:comment "obsolete. Subsumed into MPATH:202"^^xsd:string ; rdfs:label "general immunodeficiency disease"^^xsd:string ; owl:deprecated true . obo:MPATH_204 obo:IAO_0000115 "chronic/recurrent inflammatory disease"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:204"^^xsd:string ; a owl:Class ; rdfs:comment "obsolete. Subsumed into MPATH: 214."^^xsd:string ; rdfs:label "chronic/recurrent inflammatory disease"^^xsd:string ; owl:deprecated true . obo:MPATH_205 obo:IAO_0000115 "Infection with bacteria, viruses or fungi subsequent to immunodeficiency."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:205"^^xsd:string ; a owl:Class ; rdfs:label "immunodeficiency associated infection"^^xsd:string ; owl:deprecated true . obo:MPATH_206 obo:IAO_0000115 "Disease due to primary molecular or cellular defect in the immune system or its development."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:206"^^xsd:string ; a owl:Class ; rdfs:label "primary immunodeficiency disease"^^xsd:string ; rdfs:subClassOf obo:MPATH_202 . obo:MPATH_207 obo:IAO_0000115 "Primary defect in the lymphoid arm of the immune system."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:207"^^xsd:string ; a owl:Class ; rdfs:label "immunodeficiency - lymphoid defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_206 . obo:MPATH_208 obo:IAO_0000115 "Primary defect in the myeloid arm of the immune system."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:208"^^xsd:string ; a owl:Class ; rdfs:label "immunodeficiency - myeloid/phagocytic defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_206 . obo:MPATH_209 obo:IAO_0000115 "Defect in the immune system subsequent to external injury, infection, ablation or deficiency."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:209"^^xsd:string ; a owl:Class ; rdfs:label "secondary immunodeficiency disease"^^xsd:string ; rdfs:subClassOf obo:MPATH_202 . obo:MPATH_21 obo:IAO_0000115 "Defect in the structure or function of the lysosomes."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:21"^^xsd:string ; a owl:Class ; rdfs:label "lysosomal defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_17 . obo:MPATH_210 obo:IAO_0000115 "Defect in the immune system subsequent to external injury, infection or ablation."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:210"^^xsd:string ; a owl:Class ; rdfs:label "acquired immunodeficiency"^^xsd:string ; rdfs:subClassOf obo:MPATH_209 . obo:MPATH_211 obo:IAO_0000115 "Defect in the immune system subsequent to failure to attain passive immunity from maternal transfer of immunoglobulins."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:211"^^xsd:string ; a owl:Class ; rdfs:label "failed transfer of maternal immunoglobulin"^^xsd:string ; rdfs:subClassOf obo:MPATH_209 . obo:MPATH_212 obo:IAO_0000115 "A tissue reaction to an internal or external injury."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:212"^^xsd:string ; a owl:Class ; rdfs:label "inflammation"^^xsd:string ; rdfs:subClassOf obo:MPATH_194 . obo:MPATH_213 obo:IAO_0000115 "Inflammation with a recent onset, characterised histologically by primarily granulocyte infiltration, edema and hyperemia."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:213"^^xsd:string ; a owl:Class ; rdfs:comment "The five classical signs of inflammation: Rubor, tumor, calor, dolor, functio laesa (Galen 300BC)."^^xsd:string ; rdfs:label "acute inflammation"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_214 obo:IAO_0000115 "Chronic inflammatory condition characterised by infiltration of primarily lymphocytes."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:214"^^xsd:string ; a owl:Class ; rdfs:label "chronic inflammation"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_215 obo:IAO_0000115 "Nodular inflammatory reaction, containing compactly grouped epithelioid cells, giant cells, and other macrophages. The basic inflammatory unit is termed a granuloma."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:215"^^xsd:string ; a owl:Class ; rdfs:label "granulomatous inflammation"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_216 obo:IAO_0000115 "Acute inflammatory reaction in which the predominant histological change is rapid diffuse necrosis throughout the affected tissue."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:216"^^xsd:string ; a owl:Class ; rdfs:label "necrotic inflammation"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_217 obo:IAO_0000115 "Combination of inflammation, often suppurative or granulomatous, with ulceration."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:217"^^xsd:string ; a owl:Class ; rdfs:comment "Ulcers may be a component or inflammation. Use MPATH: Ulcer"^^xsd:string ; rdfs:label "ulcerative inflammation"^^xsd:string ; owl:deprecated true . obo:MPATH_218 obo:IAO_0000115 "A tumor resulting from abnormal and uncontrolled autonomous new cell growth (proliferation)that may be benign or malignant."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:218"^^xsd:string ; a owl:Class ; rdfs:label "neoplasm"^^xsd:string ; rdfs:subClassOf obo:MPATH_603 . obo:MPATH_219 obo:IAO_0000115 "Tumors of the skin, its constituent structures and glands including the mammary gland, apocrine and eccrine glands, hair follicles and associated structures."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:219"^^xsd:string ; a owl:Class ; rdfs:label "adnexal and skin appendage tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_218 . obo:MPATH_22 obo:IAO_0000115 "Defect in the structure or function of the mitochondria."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:22"^^xsd:string ; a owl:Class ; rdfs:label "mitochondrial defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_17 . obo:MPATH_220 obo:IAO_0000115 "Carcinoma of the glandular epithelium of apocrine glands (M-8401/3)."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:220"^^xsd:string ; a owl:Class ; rdfs:label "apocrine adenocarcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_219, obo:MPATH_268 . obo:MPATH_221 obo:IAO_0000115 "Benign neoplasm of the epithelium of apocrine glands (M-8401/0)."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:221"^^xsd:string ; a owl:Class ; rdfs:label "apocrine adenoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_219, obo:MPATH_270 . obo:MPATH_222 obo:IAO_0000115 "Malignant carcinoma of the ceruminous gland (M-8420/3)."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:222"^^xsd:string ; a owl:Class ; rdfs:label "ceruminous adenocarcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_219, obo:MPATH_268 . obo:MPATH_223 obo:IAO_0000115 "Benign adenomatous neoplasia of the ceruminous glands of the external auditory meatus (M-8420/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:223"^^xsd:string ; a owl:Class ; rdfs:label "ceruminous adenoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_219, obo:MPATH_270 . obo:MPATH_224 obo:IAO_0000115 "Tumor derived from eccrine sweat glands composed of clear glycogen rich cells. ( M-84020 )."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Eccrine acrospiroma"^^xsd:string, "nodular hidradenoma"^^xsd:string ; oboInOwl:id "MPATH:224"^^xsd:string ; a owl:Class ; rdfs:label "clear cell hidradenoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_219, obo:MPATH_270 . obo:MPATH_225 obo:IAO_0000115 "Malignant neoplasm of the eccrine gland (M-8413/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:225"^^xsd:string ; a owl:Class ; rdfs:label "eccrine gland adenocarcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_219, obo:MPATH_268 . obo:MPATH_226 obo:IAO_0000115 "Benign neoplasm of the eccrine gland (M-8408/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:226"^^xsd:string ; a owl:Class ; rdfs:label "eccrine gland adenoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_219, obo:MPATH_270 . obo:MPATH_227 obo:IAO_0000115 "Papillary form of eccrine sweat gland adenoma. (M -8408/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Papillary adenoma"^^xsd:string, "benign neoplasm of the eccrine gland, papillary form"^^xsd:string ; oboInOwl:id "MPATH:227"^^xsd:string ; a owl:Class ; rdfs:label "eccrine papillary adenoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_219, obo:MPATH_270 . obo:MPATH_228 obo:IAO_0000115 "Benign apocrine sweat gland tumor (8405/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Hidradenoma papilliferum"^^xsd:string ; oboInOwl:id "MPATH:228"^^xsd:string ; a owl:Class ; rdfs:label "papillary hidradenoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_219, obo:MPATH_270 . obo:MPATH_229 obo:IAO_0000115 "Malignant neoplasm of the sebaceous cells - rare areas of differentiation, severe nuclear atypia (M-8410/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "sebaceous carcinoma"^^xsd:string ; oboInOwl:id "MPATH:229"^^xsd:string ; a owl:Class ; rdfs:label "sebaceous adenocarcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_219, obo:MPATH_268 . obo:MPATH_23 obo:IAO_0000115 "Defect in the structure or function of the peroxysomes."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:23"^^xsd:string ; a owl:Class ; rdfs:label "peroxysomal defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_17 . obo:MPATH_230 obo:IAO_0000115 "Adenoma of sebaceous cells; regular architecture of gland not mantained. Large numbers of immature germinative cells present. Mitoses. (M-8410/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Epithelioma"^^xsd:string ; oboInOwl:id "MPATH:230"^^xsd:string ; a owl:Class ; rdfs:label "sebaceous adenoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_219, obo:MPATH_270 . obo:MPATH_231 obo:IAO_0000115 "A benign, often multiple, sometimes eruptive neoplasm of the sweat gland ducts composed of very small round cysts. (M-8407/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:231"^^xsd:string ; a owl:Class ; rdfs:label "syringoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_219 . obo:MPATH_232 obo:IAO_0000115 "Multiple small benign nodules derived from basal cells of hair follicles enclosing small cornified cell containing cysts. (M-8100/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Epithelioma adenoides cysticum"^^xsd:string, "benign"^^xsd:string, "hair follicle tumor"^^xsd:string ; oboInOwl:id "MPATH:232"^^xsd:string ; a owl:Class ; rdfs:label "trichoepithelioma"^^xsd:string ; rdfs:subClassOf obo:MPATH_575 . obo:MPATH_233 obo:IAO_0000115 "Well circumscribed tumor of the basal cells of the epidermis. Rare mitotic figures, benign. (M8147/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Benign basal cell tumor"^^xsd:string, "basal cell adenoma"^^xsd:string ; oboInOwl:id "MPATH:233"^^xsd:string ; a owl:Class ; rdfs:label "basal cell tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_219, obo:MPATH_270 . obo:MPATH_234 obo:IAO_0000115 "Malignant neoplasm of the basal cells of the epidermis with local invasion. (M-8090/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:234"^^xsd:string ; a owl:Class ; rdfs:label "basal cell carcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_549, obo:MPATH_575 . obo:MPATH_235 obo:IAO_0000115 "Tumor of venous or arterial vessels or capillaries."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:235"^^xsd:string ; a owl:Class ; rdfs:label "blood vessel tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_218 . obo:MPATH_236 obo:IAO_0000115 ".A benign neoplasm of fibrous tissue in which there are multiple large and small dilated vascular channels ( M9160/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Telangiectatic fibroma"^^xsd:string ; oboInOwl:id "MPATH:236"^^xsd:string ; a owl:Class ; rdfs:label "angiofibroma"^^xsd:string ; rdfs:subClassOf obo:MPATH_235 . obo:MPATH_237 obo:IAO_0000115 "An intradermal capillary telangiectasis with hyperkeratosis and acanthosis (M-9141/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "keratoangioma"^^xsd:string, "telangiectasia verrucosa"^^xsd:string, "telangiectatic wart"^^xsd:string ; oboInOwl:id "MPATH:237"^^xsd:string ; a owl:Class ; rdfs:label "angiokeratoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_235 . obo:MPATH_238 obo:IAO_0000115 "A benign neoplasm frequently arising in the cerebellum composed of capillary vessel forming endothelial cells and stromal cells. (M-9161/1)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Angioblastoma"^^xsd:string ; oboInOwl:id "MPATH:238"^^xsd:string ; a owl:Class ; rdfs:label "hemangioblastoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_235 . obo:MPATH_239 obo:IAO_0000115 "hemangioendothelioma"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:239"^^xsd:string ; a owl:Class ; rdfs:comment "obsolete Use Hemangioma MPATH: 240"^^xsd:string ; rdfs:label "hemangioendothelioma"^^xsd:string ; owl:deprecated true . obo:MPATH_24 obo:IAO_0000115 "Defect in the structure or function of the plasma membrane."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:24"^^xsd:string ; a owl:Class ; rdfs:label "plasma membrane defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_17 . obo:MPATH_240 obo:IAO_0000115 "Neoplasm derived from endothelial cells. May be of capillary or cavernous type with large vascular channels. (M-9130/0 + M-9120/0 respectively)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Angioendothelioma."^^xsd:string, "Hemangioendothelioma, benign"^^xsd:string ; oboInOwl:id "MPATH:240"^^xsd:string ; a owl:Class ; rdfs:label "hemangioma"^^xsd:string ; rdfs:subClassOf obo:MPATH_235 . obo:MPATH_241 obo:IAO_0000115 "A vascular, usually benign, neoplasm composed of round and spindle cells derived from the pericytes and surround endothelium-lined vessels. (M-9150/0/1/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Pericytoma"^^xsd:string ; oboInOwl:id "MPATH:241"^^xsd:string ; a owl:Class ; rdfs:label "hemangiopericytoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_235 . obo:MPATH_242 obo:IAO_0000115 "Malignant neoplasm derived from pluripotential mesenchymal stem cells or endothelial cells of blood vessels. (M-9120/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Hemangioma malignant"^^xsd:string, "hemangioendothelioma malignant, angiosarcoma"^^xsd:string, "hemangioendothelioma malignant."^^xsd:string ; oboInOwl:id "MPATH:242"^^xsd:string ; a owl:Class ; rdfs:label "hemangiosarcoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_235, obo:MPATH_551 . obo:MPATH_243 obo:IAO_0000115 "Neoplasm of the neurones, glia or meninges of the CNS."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:243"^^xsd:string ; a owl:Class ; rdfs:label "central nervous system tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_218 . obo:MPATH_244 obo:IAO_0000115 "Glioma derived from astrocytes, both benign and malignant forms (M-9400/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Astrocytic glioma"^^xsd:string, "astroglioma"^^xsd:string ; oboInOwl:id "MPATH:244"^^xsd:string ; a owl:Class ; rdfs:comment "Also see comments in Weiss, W.W, Israel, M. Cobbs, C., et al. (2002) Oncogene 21, 7453-7463."^^xsd:string ; rdfs:label "astrocytoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_249 . obo:MPATH_245 obo:IAO_0000115 "Malignant neoplasm derived from the epithelial cells of the choroid plexus. (M-9390/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:245"^^xsd:string ; a owl:Class ; rdfs:label "choroid plexus carcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_549, obo:MPATH_565 . obo:MPATH_246 obo:IAO_0000115 "Benign neoplasm derived from the epithelial cells of the choroid plexus. (M-9390/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:246"^^xsd:string ; a owl:Class ; rdfs:label "choroid plexus papilloma"^^xsd:string ; rdfs:subClassOf obo:MPATH_264, obo:MPATH_565 . obo:MPATH_247 obo:IAO_0000115 "Neoplasm derived from the ependymal cells lining the ventricles and aqueduct of the brain and the central canal of the spinal cord. Malignant or benign. (M-9391/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:247"^^xsd:string ; a owl:Class ; rdfs:comment "Also see general scheme in Weiss, W.W, Israel, M. Cobbs, C., et al. (2002) Oncogene 21, 7453-7463."^^xsd:string ; rdfs:label "ependymoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_249 . obo:MPATH_248 obo:IAO_0000115 "ependymoma malignant"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:248"^^xsd:string ; a owl:Class ; rdfs:comment "obsolete -subsumed into MPATH:247"^^xsd:string ; rdfs:label "ependymoma malignant"^^xsd:string ; owl:deprecated true . obo:MPATH_249 obo:IAO_0000115 "Neoplasm derived from astrocytes and oligodendrocytes. (M-9380/3, M-9440/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:249"^^xsd:string ; a owl:Class ; rdfs:comment "Also see comments in: Weiss, W.W, Israel, M. Cobbs, C., et al. (2002) Oncogene 21, 7453-7463."^^xsd:string ; rdfs:label "glioma"^^xsd:string ; rdfs:subClassOf obo:MPATH_565 . obo:MPATH_25 obo:IAO_0000115 "Degenerative process characteristic of a particular tissue."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:25"^^xsd:string ; a owl:Class ; rdfs:label "tissue specific degenerative process"^^xsd:string ; rdfs:subClassOf obo:MPATH_14 . obo:MPATH_250 obo:IAO_0000115 "Neoplasm derived from the primitive neurectodermal cells of the cerebellum. (M-9470/3). May be considered by some authorities a synonym of PNET in the CNS."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:250"^^xsd:string ; a owl:Class ; rdfs:comment "Also see Weiss, W.W, Israel, M. Cobbs, C., et al. (2002) Oncogene 21, 7453-7463."^^xsd:string ; rdfs:label "medulloblastoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_373 . obo:MPATH_251 obo:IAO_0000115 "meningioma"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Sarcoma, meningeal ( sensu malignant tumor)"^^xsd:string ; oboInOwl:id "MPATH:251"^^xsd:string ; a owl:Class ; rdfs:comment "Benign or malignant neoplasm derived from the meninges. (M-9530/0)."^^xsd:string ; rdfs:label "meningioma"^^xsd:string ; rdfs:subClassOf obo:MPATH_566 . obo:MPATH_252 obo:IAO_0000115 "Benign or malignant neoplasm derived form oligodendrocytes (M-9450/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Glioma, oligodendritic, benign"^^xsd:string, "glioma oligodendritic, malignant"^^xsd:string ; oboInOwl:id "MPATH:252"^^xsd:string ; a owl:Class ; rdfs:comment "Also see Weiss, W.W, Israel, M. Cobbs, C., et al. (2002) Oncogene 21, 7453-7463."^^xsd:string ; rdfs:label "oligodendroglioma"^^xsd:string ; rdfs:subClassOf obo:MPATH_249 . obo:MPATH_253 obo:IAO_0000115 "Neoplasm derived from sub-ependymal astrocytes (M-9383/1)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:253"^^xsd:string ; a owl:Class ; rdfs:comment "Also see general scheme in Weiss, W.W, Israel, M. Cobbs, C., et al. (2002) Oncogene 21, 7453-7463."^^xsd:string ; rdfs:label "sub-ependymoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_249 . obo:MPATH_254 obo:IAO_0000115 "Tumors showing multiple histological componants/differentiation."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:254"^^xsd:string ; a owl:Class ; rdfs:label "complex tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_218 . obo:MPATH_255 obo:IAO_0000115 "Mixed tumor of glandular epithelia with squamous and glandular diffferentiation. (M-8570/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "adenoid squamous cell carcinoma"^^xsd:string ; oboInOwl:id "MPATH:255"^^xsd:string ; a owl:Class ; rdfs:label "adenoacanthoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_254 . obo:MPATH_256 obo:IAO_0000115 "Possible origin from smooth muscle cells or pluripotential embryonic mesenchymal cells. May show up to three cellular componants including carcinoma and sarcoma type appearances. (M-8980/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:256"^^xsd:string ; a owl:Class ; rdfs:label "carcinosarcoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_254, obo:MPATH_549, obo:MPATH_551 . obo:MPATH_257 obo:IAO_0000115 "A benign or malignant neoplasm, which may be cystic, developing from the epithelium of Rathke`s pouch and occuring with or close to the pituitary gland. (M-9350/1)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Erdheim tumor"^^xsd:string, "Pituitary adamantinoma"^^xsd:string, "Rathke pouch tumor"^^xsd:string, "pituitary ameloblastoma"^^xsd:string, "suprasellar cyst"^^xsd:string ; oboInOwl:id "MPATH:257"^^xsd:string ; a owl:Class ; rdfs:label "craniopharyngioma"^^xsd:string ; rdfs:subClassOf obo:MPATH_254 . obo:MPATH_258 obo:IAO_0000115 "Neoplasm showing multiple phases, derived from mesoderm (M-8951/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:258"^^xsd:string ; a owl:Class ; rdfs:label "mesodermal mixed tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_254 . obo:MPATH_259 obo:IAO_0000115 "Most commonly a salivary gland carcinoma of low grade malignancy composed of mucous, epidermoid, and intermediate cells. (M-8430/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:259"^^xsd:string ; a owl:Class ; rdfs:label "mucoepidermoid carcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_254 . obo:MPATH_26 obo:IAO_0000115 "Absence of hair or loss of hair."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:26"^^xsd:string ; a owl:Class ; rdfs:label "alopecia"^^xsd:string ; rdfs:subClassOf obo:MPATH_25 . obo:MPATH_260 obo:IAO_0000115 "Neoplasm usually of the uterus or adnexae containing carcinomatous and sarcomatous elements, sometimes with third or fourth components. (M-8950/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:260"^^xsd:string ; a owl:Class ; rdfs:label "mullerian mixed tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_254 . obo:MPATH_261 obo:IAO_0000115 "Embryonal tumor thought to be derived from metanephric blastema. Mono, bi or triphasic, sometimes with heterotypic differentiation. (M-8960/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "nephroma"^^xsd:string ; oboInOwl:id "MPATH:261"^^xsd:string ; a owl:Class ; rdfs:label "nephroblastoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_254 . obo:MPATH_262 obo:IAO_0000115 "A biphasic tumor containing a primitive epithelial component, that may resemble well-differentiated fetal adenocarcinoma and a primitive mesenchymal stroma, which occasionally has foci of osteosarcoma, chondrosarcoma or rhadomyosarcoma. (M-8972/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:262"^^xsd:string ; a owl:Class ; rdfs:label "pulmonary blastoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_254 . obo:MPATH_263 obo:IAO_0000115 "Sarcomatous tumors, presenting a wide histological, ultrastructural, and immunocytochemical spectrum. M-8963/3."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Malignant rhabdoid tumor"^^xsd:string ; oboInOwl:id "MPATH:263"^^xsd:string ; a owl:Class ; rdfs:label "rhabdoid sarcoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_254, obo:MPATH_551 . obo:MPATH_264 obo:IAO_0000115 "Tumors with epithelial invaginations/linings and a fibrillary and fibrocytic stroma. (M-9000 - M-9030)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:264"^^xsd:string ; a owl:Class ; rdfs:label "fibroepithelial tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_218 . obo:MPATH_265 obo:IAO_0000115 "A benign neoplasm composed of glandular and fibrous tissues, predominantly glandular. (M-9013/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Cystadenofibroma"^^xsd:string, "papillary adenofibroma"^^xsd:string ; oboInOwl:id "MPATH:265"^^xsd:string ; a owl:Class ; rdfs:label "adenofibroma"^^xsd:string ; rdfs:subClassOf obo:MPATH_264 . obo:MPATH_266 obo:IAO_0000115 "A benign neoplasm derived from glandular epithelium, in which there is a abundant stroma of proliferating fibroblasts and connective tissue. (M-9010/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:266"^^xsd:string ; a owl:Class ; rdfs:label "fibroadenoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_264 . obo:MPATH_267 obo:IAO_0000115 "Neoplasms derived from glandular epithelial cells."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:267"^^xsd:string ; a owl:Class ; rdfs:label "glandular tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_218 . obo:MPATH_268 obo:IAO_0000115 "Malignant neoplasm of epithelial cells in glandular or glandlike pattern. (M-8140/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:268"^^xsd:string ; a owl:Class ; rdfs:label "adenocarcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_267, obo:MPATH_549 . obo:MPATH_269 obo:IAO_0000115 "A noninvasive abnormal proliferation of glands believed to precede the appearance of invasive adenocarcinoma. (M-8140/2)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:269"^^xsd:string ; a owl:Class ; rdfs:label "adenocarcinoma in situ"^^xsd:string ; rdfs:subClassOf obo:MPATH_268, obo:MPATH_556 . obo:MPATH_27 obo:IAO_0000115 "Changes characterized by erosion of articular cartilage, either primary or secondary to trauma or other conditions. Not primarily an inflammatory process."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Degenerative joint disease"^^xsd:string, "osteoarthrosis"^^xsd:string ; oboInOwl:id "MPATH:27"^^xsd:string ; a owl:Class ; rdfs:label "arthrosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_25 . obo:MPATH_270 obo:IAO_0000115 "A benign epithelial neoplasm in which the tumor cells may form glands or glandlike structures. In different instances this may remain a benign tumor or progress to malignancy."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:270"^^xsd:string ; a owl:Class ; rdfs:label "adenoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_267, obo:MPATH_556 . obo:MPATH_271 obo:IAO_0000115 "Spontaneous intestinal adenoma formation. Polyps increase in number, causing symptoms of chronic colitis and potentially transform into adenocarcinoma. (M-8220/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:271"^^xsd:string ; a owl:Class ; rdfs:label "adenomatous polyposis coli"^^xsd:string ; rdfs:subClassOf obo:MPATH_267, obo:MPATH_556 . obo:MPATH_272 obo:IAO_0000115 "Benign epithelial neoplasm of the lung. (M-8140/1) 1.2.1.2 in MMHCC classification."^^xsd:string ; oboInOwl:hasDbXref "URL: http://emice.nci.nih.gov/mouse_models/organ_models/lung_models/murinecancer/tumorclass"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Bronchial adenoma"^^xsd:string, "Bronchial adenoma, BA adenoma"^^xsd:string ; oboInOwl:id "MPATH:272"^^xsd:string ; a owl:Class ; rdfs:label "bronchioloalveolar adenoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_270 . obo:MPATH_273 obo:IAO_0000115 "Malignant epithelial neoplasm of the lung. (M-8250/3) 1.2.3.2, 1.2.3.5 of MMHCC classification."^^xsd:string ; oboInOwl:hasDbXref "URL: http://emice.nci.nih.gov/mouse_models/organ_models/lung_models/murinecancer/tumorclass"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Bronchioloalveolar adenocarcinoma"^^xsd:string, "Bronchioloalveolar adenocarcinoma, bronchioalveolar carcinoma"^^xsd:string ; oboInOwl:id "MPATH:273"^^xsd:string ; a owl:Class ; rdfs:label "bronchioloalveolar carcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_268, obo:MPATH_549 . obo:MPATH_274 obo:IAO_0000115 "An adenocarcinoma characterised by the presence of varying combinations of clear and hobnail-shaped tumor cells. (M-8310/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:274"^^xsd:string ; a owl:Class ; rdfs:label "clear cell adenocarcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_268 . obo:MPATH_275 obo:IAO_0000115 "Form of carcinoma of the breast or other organ in which plugs of necrotic malignant cells are present in the ducts. (M -8501/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:275"^^xsd:string ; a owl:Class ; rdfs:label "comedocarcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_267, obo:MPATH_549 . obo:MPATH_276 obo:IAO_0000115 "Malignant neoplasm derived from glandular epithelium, in which cystic accumulations of retained secretions are formed. (M-8440/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:276"^^xsd:string ; a owl:Class ; rdfs:label "cystadenocarcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_268 . obo:MPATH_277 obo:IAO_0000115 "A benign neoplasm derived from glandular epithelium, in which cystic accumulations of retained secretions are formed. (M-8440/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:277"^^xsd:string ; a owl:Class ; rdfs:label "cystadenoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_270 . obo:MPATH_278 obo:IAO_0000115 "Originates in the follicular cells of thyroid follicles. Papillary, solid and follicular forms. (M- 8330/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Follicular carcinoma"^^xsd:string ; oboInOwl:id "MPATH:278"^^xsd:string ; a owl:Class ; rdfs:label "follicular adenocarcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_268 . obo:MPATH_279 obo:IAO_0000115 "Adenoma derived from the follicular cells of the thyroid follicles. Follicular, paipillary and solid forms. M- 8330/0."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:279"^^xsd:string ; a owl:Class ; rdfs:label "follicular adenoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_270 . obo:MPATH_28 obo:IAO_0000115 "Characterised by irregular lipid deposits in the wall of arteries, causing narrowing of their lumens and proceeding eventually to fibrosis and calcification."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:28"^^xsd:string ; a owl:Class ; rdfs:comment "Note that in mouse and rats the initial lesions are mostly in the medial layer while in human they occur in the intima."^^xsd:string ; rdfs:label "atherosclerosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_25 . obo:MPATH_280 obo:IAO_0000115 "Adenoma derived from acinar epithelium of the harderian gland. Papillary, cystic, cystic-papillary and acinar forms."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:280"^^xsd:string ; a owl:Class ; rdfs:label "Harderian gland adenoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_270 . obo:MPATH_281 obo:IAO_0000115 "Malignant tumor derived form acinar epithelium of the Harderian gland."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:281"^^xsd:string ; a owl:Class ; rdfs:label "Harderian gland carcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_267, obo:MPATH_549 . obo:MPATH_282 obo:IAO_0000115 "Derived from the mammary ductal epithelium and penetrating the stroma (M-8500/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Infiltrating ductal adenocarcinoma"^^xsd:string, "duct adenocarcinoma"^^xsd:string, "ductal carcinoma"^^xsd:string ; oboInOwl:id "MPATH:282"^^xsd:string ; a owl:Class ; rdfs:label "infiltrating duct carcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_268, obo:MPATH_549 . obo:MPATH_283 obo:IAO_0000115 "In situ carcinoma of the mammary ductal epithelium. (M- 8500/2)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Ductal carcinoma in situ"^^xsd:string, "intraductal adenocarcinoma, non-infiltrating"^^xsd:string ; oboInOwl:id "MPATH:283"^^xsd:string ; a owl:Class ; rdfs:comment "Made obsolete by inclusion in MPATH: 486 Ductal intra-epithelial neoplasia"^^xsd:string ; rdfs:label "intraductal carcinoma"^^xsd:string ; owl:deprecated true . obo:MPATH_284 obo:IAO_0000115 "Infiltrating tumor with papillary morphology derived from the breast epithelium (M-8503/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Intraductal papillary adenocarcinoma"^^xsd:string ; oboInOwl:id "MPATH:284"^^xsd:string ; a owl:Class ; rdfs:label "intraductal papillary carcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_267, obo:MPATH_549 . obo:MPATH_285 obo:IAO_0000115 "Benign papilloma arising from ductal epithelium (M- 8503/0 )."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Duct adenoma"^^xsd:string, "ductal papilloma"^^xsd:string ; oboInOwl:id "MPATH:285"^^xsd:string ; a owl:Class ; rdfs:label "intraductal papilloma"^^xsd:string ; rdfs:subClassOf obo:MPATH_267, obo:MPATH_445, [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:MPATH_286 ] . obo:MPATH_286 obo:IAO_0000115 "Diffuse multiple adenomatous papillomas derived from the ductal epithelium of the breast. (M- 8505/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Diffuse intraductal papillomatosis"^^xsd:string ; oboInOwl:id "MPATH:286"^^xsd:string ; a owl:Class ; rdfs:label "intraductal papillomatosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_267 . obo:MPATH_287 obo:IAO_0000115 "Usually pancreatic B cell derived tumors mostly producing insulin. (M- 8150/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Adenoma, endocrine pancreas"^^xsd:string, "adenomatosis"^^xsd:string, "islet (pancreatic) cell tumor benign"^^xsd:string ; oboInOwl:id "MPATH:287"^^xsd:string ; a owl:Class ; rdfs:label "islet cell adenoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_270 . obo:MPATH_288 obo:IAO_0000115 "Rare tumor of the islets of Langerhans, most of which produce insulin. (M- 8150/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Adenocarcinoma, endocrine pancreas"^^xsd:string, "islet cell tumor, malignant"^^xsd:string ; oboInOwl:id "MPATH:288"^^xsd:string ; a owl:Class ; rdfs:label "islet cell carcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_267, obo:MPATH_549 . obo:MPATH_289 obo:IAO_0000115 "A form of breast adenocarcinoma derived from lobular cells. (M-8520/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Lobular adenocarcinoma"^^xsd:string, "lobular infiltrating carcinoma"^^xsd:string ; oboInOwl:id "MPATH:289"^^xsd:string ; a owl:Class ; rdfs:label "lobular carcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_267, obo:MPATH_549 . obo:MPATH_29 obo:IAO_0000115 "Opacity of the lens."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:29"^^xsd:string ; a owl:Class ; rdfs:label "cataract"^^xsd:string ; rdfs:subClassOf obo:MPATH_1 . obo:MPATH_290 obo:IAO_0000115 "Non-infiltrating form of lobular adenocarcinoma derived from the ductal epithelium. (M-8520/2)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "mammary intra-epithelial neoplasia"^^xsd:string ; oboInOwl:id "MPATH:290"^^xsd:string ; a owl:Class ; rdfs:label "lobular carcinoma in situ"^^xsd:string ; rdfs:subClassOf obo:MPATH_267, obo:MPATH_556 . obo:MPATH_291 obo:IAO_0000115 "Derived from calcitonin-producing cells (thyroid). In humans a type of carcinoma composed of epithelial elements with considerable lymphoid stroma (breast). Not yet reported in mice. (M-8510/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Medullary adenocarcinoma"^^xsd:string ; oboInOwl:id "MPATH:291"^^xsd:string ; a owl:Class ; rdfs:label "medullary carcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_267, obo:MPATH_549 . obo:MPATH_292 obo:IAO_0000115 "Malignant neoplasm derived from a glandular epithelium, eg. Ovary. Consisting of a solid to cystic mass lined with cuboidal pleomorphic epithelial cells producing a mucinous material. (M- 8470/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:292"^^xsd:string ; a owl:Class ; rdfs:label "mucinous cystadenocarcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_276 . obo:MPATH_293 obo:IAO_0000115 "A benign neoplasm derived from glandular epithelium, in which cystic accumulations of mucinous retained secretions are formed. (M-8470/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:293"^^xsd:string ; a owl:Class ; rdfs:label "mucinous cystadenoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_270 . obo:MPATH_294 obo:IAO_0000115 "Tumor originating in myoepithelial cells of exocrine glandular structures; for example mammary gland, salivary gland and preputial/clitoral glands. (M-8982/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "myoepithelial adenoma"^^xsd:string ; oboInOwl:id "MPATH:294"^^xsd:string ; a owl:Class ; rdfs:label "myoepithelioma"^^xsd:string ; rdfs:subClassOf obo:MPATH_219, obo:MPATH_270 . obo:MPATH_295 obo:IAO_0000115 "A malignant neoplasm derived from a glandular epithelium, in which solid tumors show papillary structures projecting onto fibrovascular stroma. (M-8260/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:295"^^xsd:string ; a owl:Class ; rdfs:label "papillary adenocarcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_268 . obo:MPATH_296 obo:IAO_0000115 "A benign neoplasm derived from a glandular epithelium, in which solid tumors show papillary structures projecting onto fibrovascular stroma. (M-8260/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:296"^^xsd:string ; a owl:Class ; rdfs:label "papillary adenoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_270 . obo:MPATH_297 obo:IAO_0000115 "A malignant neoplasm derived from glandular epithelium, in which cysts contain folds or papillary projections into the lumen. (M-8450/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:297"^^xsd:string ; a owl:Class ; rdfs:label "papillary cystadenocarcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_276 . obo:MPATH_298 obo:IAO_0000115 "A benign neoplasm derived from glandular epithelium, in which cysts contain folds or papillary projections into the lumen. (M-8450/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:298"^^xsd:string ; a owl:Class ; rdfs:label "papillary cystadenoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_270 . obo:MPATH_299 obo:IAO_0000115 "Originating from differentiated cells of the pineal parenchyma. Not to be confused with human pinealoma (syn: germinoma) non-gonadal germ cell tumors found in the pineal believed to be atypical teratomas. May be benign or malignant. If ectopic teratomas/teratocarcinomas use MP322 or MP321. (M-9360/1)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:299"^^xsd:string ; a owl:Class ; rdfs:label "pinealoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_267 . obo:MPATH_3 obo:IAO_0000115 "Energy dependent cell death induced by intrinsic genetic or developmental programme, or external stimuli such as addition or withdrawal of cytokines or trophic factors, radiation, chemotherapeutic agents etc. Characterised by cell shrinkage, increases in membrane permeability, endonucleolyis and nuclear fragmentation resulting in the formation of rapidly endocytosed apoptotic bodies."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "programmed cell death"^^xsd:string ; oboInOwl:id "MPATH:3"^^xsd:string ; a owl:Class ; rdfs:label "apoptosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_2 . obo:MPATH_30 obo:IAO_0000115 "Loss of muscle fibers and elastin in the media of the aorta, with accumulation of mucopolysaccharide."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Erdheim disease"^^xsd:string, "Mucoid medial degeneration"^^xsd:string, "media necrosis aortae idiopathica cystica"^^xsd:string, "media necrosis of the aorta"^^xsd:string ; oboInOwl:id "MPATH:30"^^xsd:string ; a owl:Class ; rdfs:label "cystic medial necrosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_4 . obo:MPATH_300 obo:IAO_0000115 "Malignant neoplasms which arise from pineoblasts, the primitive pineal stem cells. (M-9362/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Mixed pineal tumor"^^xsd:string, "pineal parenchymal tumor of intermediate differentiation"^^xsd:string, "transitional pineal tumor"^^xsd:string ; oboInOwl:id "MPATH:300"^^xsd:string ; a owl:Class ; rdfs:label "pineoblastoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_267 . obo:MPATH_301 obo:IAO_0000115 "A tumor arising in the pineal gland that resembles normal pineal parenchyma. (M-9361/1)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:301"^^xsd:string ; a owl:Class ; rdfs:label "pineocytoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_267 . obo:MPATH_302 obo:IAO_0000115 "Benign tumor derived from the pituicytes ( glial cells of neurohypophysis) (M-8272/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "pituitary adenoma"^^xsd:string ; oboInOwl:id "MPATH:302"^^xsd:string ; a owl:Class ; rdfs:label "pituicytoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_270 . obo:MPATH_303 obo:IAO_0000115 "Tumor characterized by extensive spread of a mucin-secreting neoplasm along the peritoneal surfaces (M-8480/6)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:303"^^xsd:string ; a owl:Class ; rdfs:label "pseudomyxoma peritonei"^^xsd:string ; rdfs:subClassOf obo:MPATH_267 . obo:MPATH_304 obo:IAO_0000115 "Adenocarcinoma from a serous gland producing and containing serous proteinaceous secretions (M-8441/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:304"^^xsd:string ; a owl:Class ; rdfs:label "serous adenocarcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_268 . obo:MPATH_305 obo:IAO_0000115 "Ovarian cystadenoma composed of cells similar to tubal epithelium (M-8441/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:305"^^xsd:string ; a owl:Class ; rdfs:label "serous cystadenoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_270 . obo:MPATH_306 obo:IAO_0000115 "Adenocarcinoma of signet ring type arising from exocrine cells of the gastric mucosa or enterocytes of intestinal mucosa. (M-8490/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Signet ring cell adenocarcinoma"^^xsd:string, "signet ring cell carcinoma"^^xsd:string ; oboInOwl:id "MPATH:306"^^xsd:string ; a owl:Class ; rdfs:label "signet ring cell carcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_268 . obo:MPATH_307 obo:IAO_0000115 "Benign neoplasm derived from the calcitonin producing C-cells of the thyroid gland."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Adenoma, parafollicular cell"^^xsd:string, "tumor c-cell benign"^^xsd:string ; oboInOwl:id "MPATH:307"^^xsd:string ; a owl:Class ; rdfs:label "thyroid C-cell adenoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_270 . obo:MPATH_308 obo:IAO_0000115 "Malignant neoplasm derived from the calcitonin producing C-cells of the thyroid gland. (M-8510/3, M-8345/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Medullary carcinoma, parafollicular cell"^^xsd:string, "tumor c-cell malignant"^^xsd:string ; oboInOwl:id "MPATH:308"^^xsd:string ; a owl:Class ; rdfs:label "thyroid C-cell carcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_267, obo:MPATH_549 . obo:MPATH_309 obo:IAO_0000115 "Germ cell and non-germ cell tumors of the testis and ovary."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:309"^^xsd:string ; a owl:Class ; rdfs:label "gonadal tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_218 . obo:MPATH_31 obo:IAO_0000115 "Abnormal accumulation of air in the interstitial connective tissue of a structure. Sensu Lung: Pulmonary emphysema; characterised by abnormal increase in the size of air (alveolar) spaces distal to the terminal bronchiole with degenerative changes in their walls and reduction in their number."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:31"^^xsd:string ; a owl:Class ; rdfs:label "emphysema"^^xsd:string ; rdfs:subClassOf obo:MPATH_25 . obo:MPATH_310 obo:IAO_0000115 "Neoplasms derived from germ cells. May be gonadal or extragonadal and are derived from primordial germ cells."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:310"^^xsd:string ; a owl:Class ; rdfs:label "germ cell tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_309 . obo:MPATH_311 obo:IAO_0000115 "Cystic ovarian teratomas with different mature cell types (M-9084/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:311"^^xsd:string ; a owl:Class ; rdfs:label "dermoid cyst"^^xsd:string ; rdfs:subClassOf obo:MPATH_254, obo:MPATH_310, obo:MPATH_549 . obo:MPATH_312 obo:IAO_0000115 "Undifferentiated germ cell tumor of the ovary composed of solid sheets of large polygonal cells with rim of clear cytoplasm (M-9060/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Seminoma (sensu male)"^^xsd:string ; oboInOwl:id "MPATH:312"^^xsd:string ; a owl:Class ; rdfs:label "dysgerminoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_310 . obo:MPATH_313 obo:IAO_0000115 "Germ cell derived malignant neoplasm of the testis or ovary, composed of anaplastic cells with indistinct cellular borders and large ovoid, round, or bean-shaped nuclei that may have large nucleoli. (M-9070/3 )."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:313"^^xsd:string ; a owl:Class ; rdfs:label "embryonal carcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_310, obo:MPATH_549 . obo:MPATH_314 obo:IAO_0000115 "Germ cell derived tumors resembling parietal or visceral yolk sac endoderm derivatives. Abundant eosinophilic matrix surrounding nests and cords of neoplastic cells. (M-9071-3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Yolk sac carcinoma"^^xsd:string ; oboInOwl:id "MPATH:314"^^xsd:string ; a owl:Class ; rdfs:label "endodermal sinus tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_310, obo:MPATH_549 . obo:MPATH_315 obo:IAO_0000115 "Gonadal neoplasms that consist of aggregates of germ cells and sex cord elements (M-9073/1)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Gonocytoma"^^xsd:string ; oboInOwl:id "MPATH:315"^^xsd:string ; a owl:Class ; rdfs:label "gonadoblastoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_310 . obo:MPATH_316 obo:IAO_0000115 "Malignant neoplasm of the testis/ovary including various elements of germ cell tumors (M-9085/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Mixed teratoma and seminoma"^^xsd:string ; oboInOwl:id "MPATH:316"^^xsd:string ; a owl:Class ; rdfs:label "mixed germ cell tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_254, obo:MPATH_310 . obo:MPATH_317 obo:IAO_0000115 "Tumor derived from spermatogenic cells resembling spermatogenia or spermatocytes. NOS ( M9061/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Germinoma, malignant"^^xsd:string, "dysgerminoma"^^xsd:string, "spermatoblastoma"^^xsd:string, "spermatocytoma, malignant."^^xsd:string ; oboInOwl:id "MPATH:317"^^xsd:string ; a owl:Class ; rdfs:label "seminoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_310 . obo:MPATH_318 obo:IAO_0000115 "As MPATH:317, but not spermatocytic (M-9061/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:318"^^xsd:string ; a owl:Class ; rdfs:label "classical seminoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_317 . obo:MPATH_319 obo:IAO_0000115 "Neoplasm of the testis usually found within the tubule. Some debate as to whether it is of germ cell origin in contrast to classical seminoma. Three types of cells are identified in spermatocytic seminomas: those with small, intermediate, and large nuclei in humans. (M-9063/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Spermatoma"^^xsd:string ; oboInOwl:id "MPATH:319"^^xsd:string ; a owl:Class ; rdfs:label "spermatocytic seminoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_317 . obo:MPATH_32 obo:IAO_0000115 "Increase in the intraocular pressure."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:32"^^xsd:string ; a owl:Class ; rdfs:label "glaucoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_25 . obo:MPATH_320 obo:IAO_0000115 "Rare ovarian tumor, regarded as monodermal teratoma, in which thyroid tissue has surpassed the other elements; occasionally associated with hyperthyroidism (M-9090/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:320"^^xsd:string ; a owl:Class ; rdfs:label "struma ovarii"^^xsd:string ; rdfs:subClassOf obo:MPATH_310, obo:MPATH_549 . obo:MPATH_321 obo:IAO_0000115 "Mixed germ cell neoplasm contaning elements of embryonal carcinoma and teratoma (M-9081/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:321"^^xsd:string ; a owl:Class ; rdfs:label "teratocarcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_254, obo:MPATH_310, obo:MPATH_549 . obo:MPATH_322 obo:IAO_0000115 "Generally benign germ cell derived tumors of male or female containing derivatives from all three germ layers with differentiation in the malignant form being poor. Malignant tumors are highly metatstatic. (M-9080/1)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:322"^^xsd:string ; a owl:Class ; rdfs:label "teratoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_254, obo:MPATH_310 . obo:MPATH_323 obo:IAO_0000115 "Neoplasms derived from the non-germ cell derived tissues of the testis and ovary."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:323"^^xsd:string ; a owl:Class ; rdfs:label "gonadal somatic cell tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_309 . obo:MPATH_324 obo:IAO_0000115 "obsolete use Sertoli cell tumor MPATH: 331."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:324"^^xsd:string ; a owl:Class ; rdfs:label "androblastoma"^^xsd:string ; owl:deprecated true . obo:MPATH_325 obo:IAO_0000115 "obsolete use thecoma MPATH:334."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:325"^^xsd:string ; a owl:Class ; rdfs:label "fibrothecoma"^^xsd:string ; owl:deprecated true . obo:MPATH_326 obo:IAO_0000115 ". Derived from sex cord stromal cells. In male thought to be Sertoli cells. (M- 8620/1)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Tumor, sex cord stromal, benign, granulosa cell type"^^xsd:string, "gynoblastoma (sensu malignant form in ovary)"^^xsd:string ; oboInOwl:id "MPATH:326"^^xsd:string ; a owl:Class ; rdfs:label "granulosa cell tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_323 . obo:MPATH_327 obo:IAO_0000115 "gynandroblastoma"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:327"^^xsd:string ; a owl:Class ; rdfs:comment "obsolete Use sertoli-leydig cell tumor MPATH 332"^^xsd:string ; rdfs:label "gynandroblastoma"^^xsd:string ; owl:deprecated true . obo:MPATH_328 obo:IAO_0000115 "Tumor derived from Leydig cells (M-8650/1)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Interstitial cell tumor, benign"^^xsd:string, "Leydig cell adenoma"^^xsd:string ; oboInOwl:id "MPATH:328"^^xsd:string ; a owl:Class ; rdfs:label "leydig cell tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_323 . obo:MPATH_329 obo:IAO_0000115 "Tumor derived from sex cords composed of highly luteinised cells with extensive pale granular cytoplasm. (M- 8610/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Luteoma"^^xsd:string, "luteinised granulosa cell tumor, benign. Gonadal sex cord stromal tumor, benign, luteoma type"^^xsd:string ; oboInOwl:id "MPATH:329"^^xsd:string ; a owl:Class ; rdfs:label "luteal cell tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_323 . obo:MPATH_33 obo:IAO_0000115 "Accumulation of substances within, on the surface of or between cells."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:33"^^xsd:string ; a owl:Class ; rdfs:label "intracellular and extracellular accumulation"^^xsd:string ; rdfs:subClassOf obo:MPATH_1 . obo:MPATH_330 obo:IAO_0000115 "Tumor consists of a mixture of granulosa, luteal thecal, Sertoli and stromal cells. (M-8590/1)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:330"^^xsd:string ; a owl:Class ; rdfs:label "ovarian stromal tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_254, obo:MPATH_323 . obo:MPATH_331 obo:IAO_0000115 "Tumor derived from sex cord/stromal cells; Sertoli cells and can occur in both testis and ovary. (M-8640/1)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Androblastoma"^^xsd:string, "arrhenoblastoma"^^xsd:string, "gonadal stromal tumor"^^xsd:string, "sex cord stromal tumor"^^xsd:string, "sustentacluar tumor"^^xsd:string ; oboInOwl:id "MPATH:331"^^xsd:string ; a owl:Class ; rdfs:label "sertoli cell tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_323 . obo:MPATH_332 obo:IAO_0000115 "Tumor of the ovary or testis containing granulosa or theca cell elements with a tubular componant of Sertoli cell type and producing simultaneous androgenic and estrogenic effects. (M-8631/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Gynandroblastoma"^^xsd:string ; oboInOwl:id "MPATH:332"^^xsd:string ; a owl:Class ; rdfs:label "sertoli-leydig cell tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_323 . obo:MPATH_333 obo:IAO_0000115 "sex cord tumor"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:333"^^xsd:string ; a owl:Class ; rdfs:comment "obsolete: Use more specific terms: MPATH: 334, 331, 329, 326"^^xsd:string ; rdfs:label "sex cord tumor"^^xsd:string ; owl:deprecated true . obo:MPATH_334 obo:IAO_0000115 "Derived from sex cord stromal cells, spindle shaped cells arranged in whorls or interlacing bundles. (M- 8600/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Fibrothecoma"^^xsd:string, "theca cell tumor"^^xsd:string ; oboInOwl:id "MPATH:334"^^xsd:string ; a owl:Class ; rdfs:label "thecoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_323 . obo:MPATH_335 obo:IAO_0000115 "Proliferative disorders and malignancies of the lymphoid and non lymphoid haematopoietic lineages."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:335"^^xsd:string ; a owl:Class ; rdfs:label "hematopoietic/lymphoid malignancies/disorder"^^xsd:string ; rdfs:subClassOf obo:MPATH_218 . obo:MPATH_336 obo:IAO_0000115 "leukaemia"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:336"^^xsd:string ; a owl:Class ; rdfs:comment "obsolete folowing reclassification."^^xsd:string ; rdfs:label "leukaemia"^^xsd:string ; owl:deprecated true . obo:MPATH_337 obo:IAO_0000115 "Leukaemia with at least 50% of nucleated erythroid cells infiltrating haematopoietic tissue."^^xsd:string ; oboInOwl:hasDbXref "URL:http://www.bloodjournal.org/cgi/content/full/100/1/238/DC1/2"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:337"^^xsd:string ; a owl:Class ; rdfs:label "erythroid leukaemia"^^xsd:string ; rdfs:subClassOf obo:MPATH_496 . obo:MPATH_338 obo:IAO_0000115 "granulocytic leukaemia"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:338"^^xsd:string ; a owl:Class ; rdfs:comment "obsolete following reclassification see: MPATH505"^^xsd:string ; rdfs:label "granulocytic leukaemia"^^xsd:string ; owl:deprecated true . obo:MPATH_339 obo:IAO_0000115 "lymphatic leukaemia"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:339"^^xsd:string ; a owl:Class ; rdfs:label "lymphatic leukaemia"^^xsd:string ; owl:deprecated true . obo:MPATH_34 obo:IAO_0000115 "Extracellular deposition of amyloid protein."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Amyloidosis"^^xsd:string ; oboInOwl:id "MPATH:34"^^xsd:string ; a owl:Class ; rdfs:comment "Any group of chemically diverse proteins that appears microscopically homogeneous, but is composed of linear non-branching aggregated fibrils aranged in sheets when see under the electron microscope."^^xsd:string ; rdfs:label "amyloid deposition"^^xsd:string ; rdfs:subClassOf obo:MPATH_33 . obo:MPATH_340 obo:IAO_0000115 "Leukaemia with at least 50% of megakaryocytic cells infiltrating haematopoietic tissue."^^xsd:string ; oboInOwl:hasDbXref "URL:http://www.bloodjournal.org/cgi/content/full/100/1/238/DC1/2"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:340"^^xsd:string ; a owl:Class ; rdfs:label "megakaryocytic leukaemia"^^xsd:string ; rdfs:subClassOf obo:MPATH_496 . obo:MPATH_341 obo:IAO_0000115 "Haematopoietic proliferation with evidence of trilineage dysplasia. Less than 20% should be blasts."^^xsd:string ; oboInOwl:hasDbXref "URL:http://www.bloodjournal.org/cgi/content/full/100/1/238/DC1/2"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:341"^^xsd:string ; a owl:Class ; rdfs:label "myelodysplastic disorder"^^xsd:string ; rdfs:subClassOf obo:MPATH_508 . obo:MPATH_342 obo:IAO_0000115 "Leukaemias of the myeloid lineage."^^xsd:string ; oboInOwl:hasDbXref "URL:http://www.bloodjournal.org/cgi/content/full/100/1/238/DC1/2"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "granulocytic leukaemia"^^xsd:string ; oboInOwl:id "MPATH:342"^^xsd:string ; a owl:Class ; rdfs:label "myeloid leukaemia"^^xsd:string ; rdfs:subClassOf obo:MPATH_496 . obo:MPATH_343 obo:IAO_0000115 "lymphoma"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:343"^^xsd:string ; a owl:Class ; rdfs:comment "obsolete; divided between subtypes of MPATH516, MPATH535"^^xsd:string ; rdfs:label "lymphoma"^^xsd:string ; owl:deprecated true . obo:MPATH_344 obo:IAO_0000115 "follicle center cell lymphoma"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:344"^^xsd:string ; a owl:Class ; rdfs:comment "obsolete; see MPATH 522"^^xsd:string ; rdfs:label "follicle center cell lymphoma"^^xsd:string ; owl:deprecated true . obo:MPATH_345 obo:IAO_0000115 "immunoblastic lymphoma"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:345"^^xsd:string ; a owl:Class ; rdfs:comment "obsolete; see MPATH525"^^xsd:string ; rdfs:label "immunoblastic lymphoma"^^xsd:string ; owl:deprecated true . obo:MPATH_346 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-03-22T01:12:01Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:346"^^xsd:string ; a owl:Class ; rdfs:label "autoimmune mediated disease"^^xsd:string ; rdfs:subClassOf obo:MPATH_194 . obo:MPATH_347 obo:IAO_0000115 "small lymphocytic lymphoma"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:347"^^xsd:string ; a owl:Class ; rdfs:comment "obsolete; see MPATH520"^^xsd:string ; rdfs:label "small lymphocytic lymphoma"^^xsd:string ; owl:deprecated true . obo:MPATH_348 obo:IAO_0000115 "thymic lymphoma"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:348"^^xsd:string ; a owl:Class ; rdfs:comment "obsolete"^^xsd:string ; rdfs:label "thymic lymphoma"^^xsd:string ; owl:deprecated true . obo:MPATH_349 obo:IAO_0000115 "mast cell tumor"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:349"^^xsd:string ; a owl:Class ; rdfs:comment "obsolete; see MPATH507"^^xsd:string ; rdfs:label "mast cell tumor"^^xsd:string ; owl:deprecated true . obo:MPATH_35 obo:IAO_0000115 "Intra- or extracellular deposition of bile pigments and their metabolites."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:35"^^xsd:string ; a owl:Class ; rdfs:label "bile deposition"^^xsd:string ; rdfs:subClassOf obo:MPATH_613 . obo:MPATH_350 obo:IAO_0000115 "mastocytoma"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:350"^^xsd:string ; a owl:Class ; rdfs:comment "obsolete. See MPATH507"^^xsd:string ; rdfs:label "mastocytoma"^^xsd:string ; owl:deprecated true . obo:MPATH_351 obo:IAO_0000115 "A neoplasm in the anterior mediastinum, originating from thymic tissue, usually benign, and frequently encapsulated; occasionally invasive, but metastases are rare; histologically, consists of any type of thymic epithelial cell as well as lymphocytes that are usually abundant. (M-8580/1)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:351"^^xsd:string ; a owl:Class ; rdfs:label "thymoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_556 . obo:MPATH_352 obo:IAO_0000115 "Tumors of the liver and biliary apparatus."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:352"^^xsd:string ; a owl:Class ; rdfs:label "hepatic tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_218 . obo:MPATH_353 obo:IAO_0000115 "Benign neoplasm derived from hepatocytes. (M- 8170/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "hepatic adenoma, benign, liver cell tumor, benign"^^xsd:string, "hepatoma, benign"^^xsd:string, "nodule type A"^^xsd:string ; oboInOwl:id "MPATH:353"^^xsd:string ; a owl:Class ; rdfs:label "hepatocellular adenoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_270, obo:MPATH_352 . obo:MPATH_354 obo:IAO_0000115 "Malignant tumor derived from the bile duct epithelium. (M8160/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:354"^^xsd:string ; a owl:Class ; rdfs:label "cholangiocarcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_352, obo:MPATH_549 . obo:MPATH_355 obo:IAO_0000115 "Develops from cholangiofibrosis, fibrosis of the biliary ducts and is only potentially malignant."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:355"^^xsd:string ; a owl:Class ; rdfs:label "cholangiofibroma"^^xsd:string ; rdfs:subClassOf obo:MPATH_352 . obo:MPATH_356 obo:IAO_0000115 "Malignant neoplasm of the liver of unknown origin . Liver blastemal cells, neoplastic hepatocytes, oval cells and biliary epithelial cells have been proposed. (M- 8970/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "embryonal hepatoma"^^xsd:string, "tumor, mixed, poorly differentiated"^^xsd:string ; oboInOwl:id "MPATH:356"^^xsd:string ; a owl:Class ; rdfs:label "hepatoblastoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_352 . obo:MPATH_357 obo:IAO_0000115 "Malignant tumor derived from hepatocytes. (M- 8170/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "carcinoma, trabecular"^^xsd:string, "carcinoma, trabecular (liver)"^^xsd:string, "hepatoma, malignant"^^xsd:string, "nodule type B"^^xsd:string ; oboInOwl:id "MPATH:357"^^xsd:string ; a owl:Class ; rdfs:label "hepatocellular carcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_352, obo:MPATH_549 . obo:MPATH_358 obo:IAO_0000115 "Tumors derived from melanocytes."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:358"^^xsd:string ; a owl:Class ; rdfs:label "melanocytic tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_219 . obo:MPATH_359 obo:IAO_0000115 "Tumor of neurectodermal origin, usually melanocytes, showing dense deposition of melanin granules, although amelanotic melanomas have been reported. (M-8720/3)."^^xsd:string ; oboInOwl:hasDbXref "URL: http://emice.nci.nih.gov/emice/mouse_models/organ_models/skin_models/malignant_melanoma#melanoma_table"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "melanosarcoma"^^xsd:string, "melanosarcoma, malignant melanoma"^^xsd:string ; oboInOwl:id "MPATH:359"^^xsd:string ; a owl:Class ; rdfs:label "melanoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_358 . obo:MPATH_36 obo:IAO_0000115 "Intra or extracellular deposition of calcium usually as calcium phosphate."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:36"^^xsd:string ; a owl:Class ; rdfs:label "calcium deposition"^^xsd:string ; rdfs:subClassOf obo:MPATH_555 . obo:MPATH_360 obo:IAO_0000115 "A potentially malignant lesion, melanoma in situ is the first phase of growth of melanoma, in which it is still confined to the epithelial domain (epidermis and adnexa) and has not passed through the basement membrane. (M-8720/2)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "level I melanoma"^^xsd:string ; oboInOwl:id "MPATH:360"^^xsd:string ; a owl:Class ; rdfs:label "melanoma in situ"^^xsd:string ; rdfs:subClassOf obo:MPATH_358, obo:MPATH_556 . obo:MPATH_361 obo:IAO_0000115 "Local lesion of the skin, often colored by hyperpigmentation or increased vascularity. May be predominantly epidermal, adnexal, melanocytic, vascular, or mesodermal, or a compound overgrowth of these tissues. Not necessarily pre-malignant. (M-8720/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "mole (sensu melanocytic nevus)"^^xsd:string ; oboInOwl:id "MPATH:361"^^xsd:string ; a owl:Class ; rdfs:label "naevus"^^xsd:string ; rdfs:subClassOf obo:MPATH_358 . obo:MPATH_362 obo:IAO_0000115 "Benign or malignant neoplasm of the ovary and corpus uteri, thought to originate in mesonephric structures. (M-9110/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "mesonephric adenocarcinoma, wolffian duct carcinoma, mesonephroid tumor"^^xsd:string ; oboInOwl:id "MPATH:362"^^xsd:string ; a owl:Class ; rdfs:label "mesonephroma"^^xsd:string ; rdfs:subClassOf obo:MPATH_268 . obo:MPATH_363 obo:IAO_0000115 "Tumor beleived to be derived from mesonephric remnants. (M-8310/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "mesonephroid clear cell adenocarcinoma"^^xsd:string ; oboInOwl:id "MPATH:363"^^xsd:string ; a owl:Class ; rdfs:label "mesonephric tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_362 . obo:MPATH_364 obo:IAO_0000115 "mesothelial tumor"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:364"^^xsd:string ; a owl:Class ; rdfs:comment "obsolete; subsumed into MPATH365"^^xsd:string ; rdfs:label "mesothelial tumor"^^xsd:string ; owl:deprecated true . obo:MPATH_365 obo:IAO_0000115 "Benign or malignant neoplasm derived from the lining cells of the pleura and peritoneum, composed of spindle cells or fibrous tissue which may enclose glandlike spaces lined by cuboidal cells. Epithelioid, fibrous, cystis, papillary, and sarcomatoid variants. (M- 9050/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:365"^^xsd:string ; a owl:Class ; rdfs:label "mesothelioma"^^xsd:string ; rdfs:subClassOf obo:MPATH_218 . obo:MPATH_366 obo:IAO_0000115 "Neoplasms derived from the neuroendocrine system."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:366"^^xsd:string ; a owl:Class ; rdfs:label "neuroendocrine tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_218 . obo:MPATH_367 obo:IAO_0000115 "Carcinoid tumors are of neuroendocrine origin and derived from primitive stem cells. Found predominantly in the lung and gut they are capable of secreting a large range of substances and have a number of histological subtypes. May resemble but are distinct from small cell lung carcinoma in the lung. (M-8240/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:367"^^xsd:string ; a owl:Class ; rdfs:label "carcinoid tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_366 . obo:MPATH_368 obo:IAO_0000115 "obsolete."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:368"^^xsd:string ; a owl:Class ; rdfs:label "endocrine adenocarcinoma"^^xsd:string ; owl:deprecated true . obo:MPATH_369 obo:IAO_0000115 "endocrine adenoma"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:369"^^xsd:string ; a owl:Class ; rdfs:label "endocrine adenoma"^^xsd:string ; owl:deprecated true . obo:MPATH_37 obo:IAO_0000115 "Intracellular deposition of golden or yellow-brown pigment, acid fast and insoluble in lipid solvents. Believed to be a type of lipofuscin."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:37"^^xsd:string ; a owl:Class ; rdfs:label "ceroid deposition"^^xsd:string ; rdfs:subClassOf obo:MPATH_613 . obo:MPATH_370 obo:IAO_0000115 "Primitive neuroectodermal tumors (PNET) are neoplasms derived from primitive neural stem cells either in the CNS or the periphery . These are small-cell, malignant embryonal tumors showing divergent differentiation of variable degree along neuronal, glial, or rarely mesenchymal lines. (M-9473/3, M-9364/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "PNET"^^xsd:string ; oboInOwl:id "MPATH:370"^^xsd:string ; a owl:Class ; rdfs:label "primitive neurectodermal tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_373, obo:MPATH_570 . obo:MPATH_371 obo:IAO_0000115 "Neuroendocrine cell derived anaplastic carcinoma composed of small cells, usually of the lung producing a variety of peptide hormones. (M-8041/3). 1.2.3.4 of MMHCC classification."^^xsd:string ; oboInOwl:hasDbXref "URL: http://emice.nci.nih.gov/mouse_models/organ_models/lung_models/murinecancer/tumorclass"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "oat cell carcinoma"^^xsd:string ; oboInOwl:id "MPATH:371"^^xsd:string ; a owl:Class ; rdfs:comment "see: Meuwissen, R., Linn, S.C., Linnoila, R.I. et al. (2003) Induction of small cell lung cancer by somatic inactivation of both Trp53 and Rb1 in a conditional mouse model. Cancer cell, 4: 181-189. AND Calbo, J., Meuwissen, R., van Montfort, E. et al. (2005) Genotype-phenotype relationships in a mouse model for human small-cell lung cancer. Cold Spring Harbor symposia on quantitative biology, 70: 225-232. AND Meuwissen, R. and Berns, A. (2005) Mouse models for human lung cancer. Genes & development, 19: 643-664."^^xsd:string ; rdfs:label "small cell carcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_366, obo:MPATH_549 . obo:MPATH_372 obo:IAO_0000115 "Small disseminated foci of atypical bronchiolar epithelial hyperplasia. Benign. (M- 8040/1)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:372"^^xsd:string ; a owl:Class ; rdfs:label "tumorlet"^^xsd:string ; rdfs:subClassOf obo:MPATH_366 . obo:MPATH_373 obo:IAO_0000115 "Neoplasms derived from neuroepithelial precursors."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:373"^^xsd:string ; a owl:Class ; rdfs:comment "Renamed from neuroepitheliomatous tumor, to reflect primitive origins of this class of tumor."^^xsd:string ; rdfs:label "CNS progenitor tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_565 . obo:MPATH_374 obo:IAO_0000115 "A neoplasm of immature, poorly differentiated neuronal cells believed to arise from neuroepithelial precursors in the olfactory epithelium. (M- 9522/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "neuroblastoma, olfactory"^^xsd:string, "neuroepithelial carcinoma"^^xsd:string, "neuroepithelioma, olfactory"^^xsd:string ; oboInOwl:id "MPATH:374"^^xsd:string ; a owl:Class ; rdfs:label "esthesioneuroblastoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_373 . obo:MPATH_375 obo:IAO_0000115 "A benign neoplasm composed of mature ganglionic neurons scattered singly or in clumps within a relatively abundant and dense stroma of neurofibrils and collagenous fibers. (M-9490/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:375"^^xsd:string ; a owl:Class ; rdfs:label "ganglioneuroma"^^xsd:string ; rdfs:subClassOf obo:MPATH_570 . obo:MPATH_376 obo:IAO_0000115 "A malignant neoplasm characterized by immature, poorly differentiated nerve cells of embryonic type. (M-9500/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:376"^^xsd:string ; a owl:Class ; rdfs:label "neuroblastoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_373 . obo:MPATH_377 obo:IAO_0000115 "A catecholamine-secreting tumor arising from the chromaffin cells of the sympathetic nervous system or adrenal medulla. May be benign or malignant. [See MPATH 398]. (M- 8510/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:377"^^xsd:string ; a owl:Class ; rdfs:label "pheochromocytoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_366 . obo:MPATH_378 obo:IAO_0000115 "Malignant juvenile neoplasm of the eye derived from primitive retinal precursor cells. (M- 9510/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:378"^^xsd:string ; a owl:Class ; rdfs:label "retinoblastoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_373 . obo:MPATH_379 obo:IAO_0000115 "Neoplasm arising from the tissues of the odontogenic apparatus. These tumors are derived from ectodermal tissue (epithelial tumors) or from mesodermal tissue (connective tissue tumors) or are composed of both components (mixed or composite odontogenic tumors) ."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:379"^^xsd:string ; a owl:Class ; rdfs:label "odontogenic tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_218 . obo:MPATH_38 obo:IAO_0000115 "Intra and extracellular deposition of copper and copper containing proteins."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:38"^^xsd:string ; a owl:Class ; rdfs:label "copper deposition"^^xsd:string ; rdfs:subClassOf obo:MPATH_45, obo:MPATH_555 . obo:MPATH_380 obo:IAO_0000115 "A tumor consisting of proliferating strands and clumps of odontogenic epithelium in a highly cellular fibroblastic stroma resembling the dental papilla of developing teeth. The epithelial component are composed of peripheral cuboidal or cylindrical cells enclosing scant stellate cells. (M-9330/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:380"^^xsd:string ; a owl:Class ; rdfs:label "ameloblastic fibroma"^^xsd:string ; rdfs:subClassOf obo:MPATH_379 . obo:MPATH_381 obo:IAO_0000115 "Benign odontogenic epithelial neoplasm that histologically mimics the embryonic enamel organ but does not differentiate to the point of forming dental hard tissue. Histologically dominated by epithelial cells in a scant fibroblastic stroma. (M-9310/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:381"^^xsd:string ; a owl:Class ; rdfs:label "ameloblastoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_379 . obo:MPATH_382 obo:IAO_0000115 "Benign neoplasm derived from pluripotential mesenchymal cells or cementoblasts. Well demarcated tumor occurring exclusively in the jaw containing spindle cells which undergo transformation to cuboidal cementoblasts forming multiple cementicle like bodies. ( M-9274/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "ossifying fibroma, cemento-ossifying fibroma"^^xsd:string ; oboInOwl:id "MPATH:382"^^xsd:string ; a owl:Class ; rdfs:label "cementifying fibroma"^^xsd:string ; rdfs:subClassOf obo:MPATH_379 . obo:MPATH_383 obo:IAO_0000115 "A neoplasm arising from the periodontal ligament (M-9273/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "True cementoma"^^xsd:string ; oboInOwl:id "MPATH:383"^^xsd:string ; a owl:Class ; rdfs:label "cementoblastoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_379 . obo:MPATH_384 obo:IAO_0000115 "Reactive fibro-osseous lesion derived from odotongenic cells in the periodontal ligament (M-9272/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:384"^^xsd:string ; a owl:Class ; rdfs:label "cementoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_379 . obo:MPATH_385 obo:IAO_0000115 "Similar lesion to ameloblastic fibroma (MPATH380) , but also showing inductive changes that lead to the formation of dentine (M-9271/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "ameloblastic fibrodentinoma"^^xsd:string ; oboInOwl:id "MPATH:385"^^xsd:string ; a owl:Class ; rdfs:label "dentinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_379 . obo:MPATH_386 obo:IAO_0000115 "odontogenic tumor"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:386"^^xsd:string ; a owl:Class ; rdfs:comment "redundant"^^xsd:string ; rdfs:label "odontogenic tumor"^^xsd:string ; owl:deprecated true . obo:MPATH_387 obo:IAO_0000115 "Hamartomatous malformation of odontogenic tissue. It may vary from nondescript masses of dental tissue (complex odontoma) to multiple well-formed teeth (compound odontoma). Cf ameloblastic fibro-odontoma. (M-9280/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:387"^^xsd:string ; a owl:Class ; rdfs:label "odontoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_254, obo:MPATH_379, obo:MPATH_74 . obo:MPATH_388 obo:IAO_0000115 "Neoplasms of bone and cartilage."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:388"^^xsd:string ; a owl:Class ; rdfs:label "osseous and chondromatous tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_218 . obo:MPATH_389 obo:IAO_0000115 "A benign or malignant neoplasm occuring in the epiphyses of long bones, consisting of highly cellular tissue resembling embryonic cartilage. (M-9230/0, /3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:389"^^xsd:string ; a owl:Class ; rdfs:label "chondroblastoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_388 . obo:MPATH_39 obo:IAO_0000115 "Intracellular deposition of glycogen."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:39"^^xsd:string ; a owl:Class ; rdfs:label "glycogen deposition"^^xsd:string ; rdfs:subClassOf obo:MPATH_33 . obo:MPATH_390 obo:IAO_0000115 "chondroblastoma, malignant"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:390"^^xsd:string ; a owl:Class ; rdfs:comment "Subsumed into MPATH:389"^^xsd:string ; rdfs:label "chondroblastoma, malignant"^^xsd:string ; owl:deprecated true . obo:MPATH_391 obo:IAO_0000115 "A benign neoplasm derived from mesodermal cells that form cartilage composed of well differentiated hyaline cartilage (M-9220/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:391"^^xsd:string ; a owl:Class ; rdfs:label "chondroma"^^xsd:string ; rdfs:subClassOf obo:MPATH_388 . obo:MPATH_392 obo:IAO_0000115 "Malignant neoplasm derived form pluripotential mesenchymal cells, chondrocytes or chondroblasts. No production of osteoid. (M-9220/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:392"^^xsd:string ; a owl:Class ; rdfs:label "chondrosarcoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_388 . obo:MPATH_393 obo:IAO_0000115 "Generally benign osteogenic neoplasm of unknown aetiology. Aggressive form may be confused with osteosarcoma. NOT a syn for osteofibroma. (M-9200/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "giant osteoid osteoma, benign osteoblastoma"^^xsd:string ; oboInOwl:id "MPATH:393"^^xsd:string ; a owl:Class ; rdfs:label "osteoblastoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_388 . obo:MPATH_394 obo:IAO_0000115 "Benign bone tumor characterized by hyaline cartilage capped bony growths that project from the surface of the affected bone. (M-9210/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "cartilaginous exostosis"^^xsd:string ; oboInOwl:id "MPATH:394"^^xsd:string ; a owl:Class ; rdfs:label "osteochondroma"^^xsd:string ; rdfs:subClassOf obo:MPATH_388 . obo:MPATH_395 obo:IAO_0000115 "Benign neoplasm derived from pluripotential mesenchymal stem cells or osteoblasts composed of mature nbone trabelculae seperated by a stroma of spindle cells. (M- 9262/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:395"^^xsd:string ; a owl:Class ; rdfs:label "osteofibroma"^^xsd:string ; rdfs:subClassOf obo:MPATH_388 . obo:MPATH_396 obo:IAO_0000115 "Benign neoplasm derived from osteoblasts or osteocytes composed of very dense bone with predominantly woven structure. ( M-9180/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "cancellous osteoma"^^xsd:string, "compact osteoma"^^xsd:string, "juxtacortical osteoma"^^xsd:string, "medullary osteoma"^^xsd:string, "osteoid osteoma"^^xsd:string, "spongious osteoma"^^xsd:string, "trabecular osteoma"^^xsd:string ; oboInOwl:id "MPATH:396"^^xsd:string ; a owl:Class ; rdfs:label "osteoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_388 . obo:MPATH_397 obo:IAO_0000115 "Malignant neoplasm derived form mesenchymal stem cells, osteoblasts or osteocytes. Highly invasive and destructive tumor rising in the skeleton with osteoid and immature woven bone. (M-9180/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "osteogenic sarcoma"^^xsd:string ; oboInOwl:id "MPATH:397"^^xsd:string ; a owl:Class ; rdfs:label "osteosarcoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_388 . obo:MPATH_398 obo:IAO_0000115 "Generally benign neoplasms of CHIEF cells arising from neuroectodermal tissues, found in various parts of the body. Note that until recently, glomus tumors were believed to be derived from specialised vascular cells, which is incorrect. Paraganglioma is the preferred term.The nomenclature for pheochromocytoma and paraganglioma is inconsistent. The term paraganglioma is used to refer to any extra-adrenal tumor of the paraganglion system or nonfunctional tumor of the paraganglion system. Functional tumors are referred extra-adrenal pheochromocytoma."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:398"^^xsd:string ; a owl:Class ; rdfs:label "paragangliomas and glomus tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_366 . obo:MPATH_399 obo:IAO_0000115 "Paraganglioma arising in the CHIEF cells of the aortic body (M-8691/1)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "aortic body paraganglioma"^^xsd:string ; oboInOwl:id "MPATH:399"^^xsd:string ; a owl:Class ; rdfs:label "aortic body tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_398 . obo:MPATH_4 obo:IAO_0000115 "Morpholological changes after intravital (Pathologic) death of one or more cells, or of a portion of tissue or organ, resulting from irreversible damage;characterised by mitochondrial swelling, nuclear pyknosis, karyolysis, swollen and abnormally pale basophilic staining; or karyorrhexis, rupture and fragmentation of the nucleus. Energy independent cf. Apoptosis MPATH 3."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:4"^^xsd:string ; a owl:Class ; rdfs:label "necrosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_2 . obo:MPATH_40 obo:IAO_0000115 "Intracellular deposition of eosinophilic material."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Hyaline degeneration, Eosinophilic cytoplasmic change"^^xsd:string ; oboInOwl:id "MPATH:40"^^xsd:string ; a owl:Class ; rdfs:label "hyalinosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_33 . obo:MPATH_400 obo:IAO_0000115 "Paraganglioma arising in the CHIEF cells of the carotid body (M-8692/1)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "carotid body paraganglioma"^^xsd:string ; oboInOwl:id "MPATH:400"^^xsd:string ; a owl:Class ; rdfs:label "carotid body tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_398 . obo:MPATH_401 obo:IAO_0000115 "A glomus tumor arising from the chief cells of the paraganglia ( neurectodermal derivatives) , or glomus bodies, located within the wall (adventitia) of the jugular bulb. (8690/1)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:401"^^xsd:string ; a owl:Class ; rdfs:label "glomus jugulare tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_398 . obo:MPATH_402 obo:IAO_0000115 "glomus tumor"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:402"^^xsd:string ; a owl:Class ; rdfs:comment "obsolete; use paraganglioma M-8711/0) or specific example terms, MPATH399-401."^^xsd:string ; rdfs:label "glomus tumor"^^xsd:string ; owl:deprecated true . obo:MPATH_403 obo:IAO_0000115 "A neoplasm composed of derivatives of CHIEF cells usually in single encapsulated nodular masses surrounded with sustentacular cells. ( M- 8711/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "chemodectomas"^^xsd:string, "glomus tumor"^^xsd:string, "non-chromaffin paragangliomas"^^xsd:string ; oboInOwl:id "MPATH:403"^^xsd:string ; a owl:Class ; rdfs:label "paraganglioma"^^xsd:string ; rdfs:subClassOf obo:MPATH_398 . obo:MPATH_404 obo:IAO_0000115 "Neoplasms of the soft and connective tissues."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:404"^^xsd:string ; a owl:Class ; rdfs:label "soft tissue tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_218 . obo:MPATH_405 obo:IAO_0000115 "Believed to arise from primitive notochord remnants . Usually occurs along the axial skeleton and is characterised by the presence of bubble cells containing large unstained cytoplasmic vacuoles with central or eccentricc nuclei. Benign but locally invasive. (M-9370/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:405"^^xsd:string ; a owl:Class ; rdfs:label "chordoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_404 . obo:MPATH_406 obo:IAO_0000115 "Highly recurrent, infiltrative skin tumors of intermediate malignancy derived from fibroblasts/fibrocytes. Human condition dermatofibrosarcoma protruberans (M-8832/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:406"^^xsd:string ; a owl:Class ; rdfs:label "dermatofibrosarcoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_404, obo:MPATH_551 . obo:MPATH_407 obo:IAO_0000115 "Benign neoplasm of fibroblasts/fibrocytes with poor/moderate cellularity. (M-8810/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:407"^^xsd:string ; a owl:Class ; rdfs:comment "\"Soft tissue\" qualifier removed by Pathology Panel to increase scope of term."^^xsd:string ; rdfs:label "fibroma"^^xsd:string ; rdfs:subClassOf obo:MPATH_404, obo:MPATH_551 . obo:MPATH_408 obo:IAO_0000115 "Malignant tumor derived from pluripotential mesenchymal stem cells; fibroblasts, fibrocytes (M-8810/3)."^^xsd:string ; oboInOwl:hasExactSynonym "fibrosarcoma"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:408"^^xsd:string ; a owl:Class ; rdfs:label "soft tissue fibrosarcoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_404, obo:MPATH_551 . obo:MPATH_409 obo:IAO_0000115 "Benign or maligant tumor derived from pluripotential mesenchymal stem cells showing fibrous and histiocytic differentiation (M-8830/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:409"^^xsd:string ; a owl:Class ; rdfs:label "fibrous histiocytoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_404 . obo:MPATH_41 obo:IAO_0000115 "Extra- or intra-cellular deposition of iron, iron containing proteins or hemosiderin."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:41"^^xsd:string ; a owl:Class ; rdfs:label "iron deposition"^^xsd:string ; rdfs:subClassOf obo:MPATH_45, obo:MPATH_555 . obo:MPATH_410 obo:IAO_0000115 "Malignant or benign tumor of pluripotential mesenchymal stem cells giving rise to large multinucleated cells (M- 9251/1)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "giant cell fibrous histiocytoma"^^xsd:string ; oboInOwl:id "MPATH:410"^^xsd:string ; a owl:Class ; rdfs:label "giant cell tumor of soft tissue"^^xsd:string ; rdfs:subClassOf obo:MPATH_404 . obo:MPATH_411 obo:IAO_0000115 "granular cell tumor/alveolar sarcoma"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:411"^^xsd:string ; a owl:Class ; rdfs:comment "obsolete. Use specific terms MPATH: 412 or MPATH: 413"^^xsd:string ; rdfs:label "granular cell tumor/alveolar sarcoma"^^xsd:string ; owl:deprecated true . obo:MPATH_412 obo:IAO_0000115 "Malignant tumor of unknown origin though probably myogenic due to expression of MyoD and other myogenic lineage markers. Consists of grouped polygonal tumor cells with granular eosinophilic cytoplasm arranged in an organ-like configuration separated by thin fibrovascular septa. Central areas within these nests of cells become necrotic, and the loss of architecture produces an alveolar appearance. (M-9581/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:412"^^xsd:string ; a owl:Class ; rdfs:label "alveolar soft part sarcoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_404, obo:MPATH_551 . obo:MPATH_413 obo:IAO_0000115 "Large polygonal or round cell tumors with abundant acidophilic cytoplasm containing PAS positive granules. Found especially in the uterine cervix. Aetiology unknown. (M-9580/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "myoblastoma"^^xsd:string ; oboInOwl:id "MPATH:413"^^xsd:string ; a owl:Class ; rdfs:label "granular cell tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_423 . obo:MPATH_414 obo:IAO_0000115 "histiocytic sarcoma"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:414"^^xsd:string ; a owl:Class ; rdfs:comment "redundant use MPATH506"^^xsd:string ; rdfs:label "histiocytic sarcoma"^^xsd:string ; owl:deprecated true . obo:MPATH_415 obo:IAO_0000115 "Tumors derived from the lipogenic lineage or showing predominantly lipomatous differentiation."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:415"^^xsd:string ; a owl:Class ; rdfs:label "lipomatous tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_404 . obo:MPATH_416 obo:IAO_0000115 "Benign renal neoplasm composed of fat, vascular, and smooth muscle elements. Associated with tuberous sclerosis in humans. Aetiology unknown, but the combination of elements may reflect a lesion specific pattern of metaplasia. (M-8860/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:416"^^xsd:string ; a owl:Class ; rdfs:label "angiomyolipoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_254, obo:MPATH_415 . obo:MPATH_417 obo:IAO_0000115 "Benign neoplasia derived from lipoblasts or lipocytes of white or brown fat. May be angiomatous or hibernomatous. (M- 8850/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:417"^^xsd:string ; a owl:Class ; rdfs:label "lipoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_415 . obo:MPATH_418 obo:IAO_0000115 "Malignant neoplasms which probably originate in primitive mesenchymal stem cell populations differentiating down a lipomatous pathway. (M-8850/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:418"^^xsd:string ; a owl:Class ; rdfs:label "liposarcoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_415, obo:MPATH_551 . obo:MPATH_419 obo:IAO_0000115 "Neoplasms of the lymphatic vessels."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:419"^^xsd:string ; a owl:Class ; rdfs:label "lymphatic vessel tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_404 . obo:MPATH_42 obo:IAO_0000115 "Extra or intracellular deposition of lipid."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:42"^^xsd:string ; a owl:Class ; rdfs:label "lipid deposition"^^xsd:string ; rdfs:subClassOf obo:MPATH_33 . obo:MPATH_420 obo:IAO_0000115 "Benign hamartomatous malformation of the lymphatic ducts. Usually found in the skin and may be superficial or deep. (M-9170/0)."^^xsd:string ; oboInOwl:hasBroadSynonym "Hygroma"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:420"^^xsd:string ; a owl:Class ; rdfs:label "lymphangioma"^^xsd:string ; rdfs:subClassOf obo:MPATH_419, obo:MPATH_74 . obo:MPATH_421 obo:IAO_0000115 "Characterized by benign peribronchial, perivascular, and perilymphatic proliferation of atypical smooth muscle resulting in vascular and airway obstruction, cyst formation, and a progressive decline in lung function. (M- 9174/1)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Lymphangioleiomyomatosis."^^xsd:string ; oboInOwl:id "MPATH:421"^^xsd:string ; a owl:Class ; rdfs:label "lymphangiomyomatosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_419 . obo:MPATH_422 obo:IAO_0000115 "A malignant neoplasm derived from vascular tissue in which the neoplastic cells originate from the endothelial cells of lymphatic vessels. (M-9170/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:422"^^xsd:string ; a owl:Class ; rdfs:label "lymphangiosarcoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_419, obo:MPATH_551 . obo:MPATH_423 obo:IAO_0000115 "Neoplasms derived from myogenic lineages or predominantly composed of cells showing myomatous differentiation."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:423"^^xsd:string ; a owl:Class ; rdfs:label "myomatous tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_404 . obo:MPATH_424 obo:IAO_0000115 "Benign leiomyoma that invades vascular spaces. (M-8890/1)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:424"^^xsd:string ; a owl:Class ; rdfs:label "intravascular leiomyomatosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_423 . obo:MPATH_425 obo:IAO_0000115 "Benign neoplasm derived from smooth muscle cells. (M-8890/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:425"^^xsd:string ; a owl:Class ; rdfs:label "leiomyoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_423 . obo:MPATH_426 obo:IAO_0000115 "Malignant tumor derived form pluripotential mesenchymal stem cells or smooth muscle cells. (M- 8890/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:426"^^xsd:string ; a owl:Class ; rdfs:label "leiomyosarcoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_423, obo:MPATH_551 . obo:MPATH_427 obo:IAO_0000115 "myoblastoma"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:427"^^xsd:string ; a owl:Class ; rdfs:comment "obsolete. Syn of granular cell tumor. MPATH 413"^^xsd:string ; rdfs:label "myoblastoma"^^xsd:string ; owl:deprecated true . obo:MPATH_428 obo:IAO_0000115 "Malignant tumor of striated muscle or pluripotential mesenchymal stem cells. (M-8900/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:428"^^xsd:string ; a owl:Class ; rdfs:label "rhabdomyosarcoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_423, obo:MPATH_551 . obo:MPATH_429 obo:IAO_0000115 "Neoplasms resembling primitive mesenchymal tissue with a soft mucous matrix."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:429"^^xsd:string ; a owl:Class ; rdfs:label "myxomatous tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_404 . obo:MPATH_43 obo:IAO_0000115 "Intracellular deposition of brown pigment granules probably representing lipid-containing residues of lysosomal digestion. Often age related."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:43"^^xsd:string ; a owl:Class ; rdfs:label "lipofuscin deposition"^^xsd:string ; rdfs:subClassOf obo:MPATH_613 . obo:MPATH_430 obo:IAO_0000115 "Angiomyxoma is a poorly circumscribed, slowly growing lesion composed of spindle-shaped and stellate cells evenly distributed in an abundant myxoid matrix. The lesion contains numerous vessels, often showing some hyalinization of their walls, and occasionally surrounded by a few smooth muscle cells. Immunohistochemically, tumor cells may express desmin and/ or smooth muscle actin (M-8841/1)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:430"^^xsd:string ; a owl:Class ; rdfs:label "angiomyxoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_429 . obo:MPATH_431 obo:IAO_0000115 "A benign neoplasm derived from pluripotential mesenchymal stem cells of connective tissue, consisting chiefly of polyhedral and stellate cells that are loosely embedded in a soft mucoid matrix. May show multiple differentiated components. (M-8840/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:431"^^xsd:string ; a owl:Class ; rdfs:label "myxoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_429 . obo:MPATH_432 obo:IAO_0000115 "A malignant neoplasm derived from pluripotential mesenchymal stem cells of connective tissue, consisting chiefly of polyhedral and stellate cells that are loosely embedded in a soft mucoid matrix. (M-8840/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:432"^^xsd:string ; a owl:Class ; rdfs:label "myxosarcoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_429, obo:MPATH_551 . obo:MPATH_433 obo:IAO_0000115 "Neoplasms of the nerve sheath."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:433"^^xsd:string ; a owl:Class ; rdfs:label "nerve sheath tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_404, obo:MPATH_570 . obo:MPATH_434 obo:IAO_0000115 "neurilemmoma"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:434"^^xsd:string ; a owl:Class ; rdfs:comment "obsolete. Use schwannoma MPATH438"^^xsd:string ; rdfs:label "neurilemmoma"^^xsd:string ; owl:deprecated true . obo:MPATH_435 obo:IAO_0000115 "Peripheral nerve tumor consisting of chaotic arrays of wavy schwann cell bundles and fibroblasts interspersed within a matrix rich in collagen and mucopolysaccharide. (M9540/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:435"^^xsd:string ; a owl:Class ; rdfs:label "neurofibroma"^^xsd:string ; rdfs:subClassOf obo:MPATH_433 . obo:MPATH_436 obo:IAO_0000115 "Systemic manifestation of MPATH:435 ( M-9540/1)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:436"^^xsd:string ; a owl:Class ; rdfs:label "neurofibromatosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_433 . obo:MPATH_437 obo:IAO_0000115 "Malignant neoplasm derived from Schwann cells. (M-9540/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "malignant peripheral nerve sheath tumor"^^xsd:string ; oboInOwl:id "MPATH:437"^^xsd:string ; a owl:Class ; rdfs:label "neurofibrosarcoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_433, obo:MPATH_551 . obo:MPATH_438 obo:IAO_0000115 "May be malignant or benign, Schwann cell derived tumor considered to be neurectodermal with some acquired mesenchymal features. (M-9560/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "neurilemoma"^^xsd:string, "neurinoma, benign"^^xsd:string ; oboInOwl:id "MPATH:438"^^xsd:string ; a owl:Class ; rdfs:label "schwannoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_433 . obo:MPATH_439 obo:IAO_0000115 "Neoplasms of synovial origin."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:439"^^xsd:string ; a owl:Class ; rdfs:label "synovial-like tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_404 . obo:MPATH_44 obo:IAO_0000115 "Intra or extracellular deposition of melanin."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:44"^^xsd:string ; a owl:Class ; rdfs:label "melanin deposition"^^xsd:string ; rdfs:subClassOf obo:MPATH_613 . obo:MPATH_440 obo:IAO_0000115 "Malignant neoplasm occurring in close association with tendon sheaths and joint capsules. Biphasic in humans , showing a mixed spindle cell and epithelioid like morphology; this is not seen in rodents to date. (M-9040/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Synovial cell sarcoma"^^xsd:string ; oboInOwl:id "MPATH:440"^^xsd:string ; a owl:Class ; rdfs:label "synovial sarcoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_439, obo:MPATH_551 . obo:MPATH_441 obo:IAO_0000115 "synovioma"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:441"^^xsd:string ; a owl:Class ; rdfs:comment "Obsolete. Use MPATH:440"^^xsd:string ; rdfs:label "synovioma"^^xsd:string ; owl:deprecated true . obo:MPATH_442 obo:IAO_0000115 "Neoplasms of stratified squamous epithelial cells."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:442"^^xsd:string ; a owl:Class ; rdfs:label "squamous cell tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_218 . obo:MPATH_443 obo:IAO_0000115 "A benign tumor consisting of villous or arborescent outgrowths of fibrovascular stroma covered by neoplastic epithelial cells in which proliferating epithelium is invaginated beneath the surface and is more smoothly rounded. (M-8053/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "endophytic papilloma"^^xsd:string, "invaginated papilloma"^^xsd:string ; oboInOwl:id "MPATH:443"^^xsd:string ; a owl:Class ; rdfs:label "inverted squamous papilloma"^^xsd:string ; rdfs:subClassOf obo:MPATH_219, obo:MPATH_442, obo:MPATH_445 . obo:MPATH_444 obo:IAO_0000115 "Skin type is thought to arise from follicular epithelium of hair follicles; found in other epithelia. Composed of multiple cup shaped cavities filled with lamellated concentrically arranged or homogeneous cornified masses."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "epithelioma, intracutaneous, cornifying"^^xsd:string ; oboInOwl:id "MPATH:444"^^xsd:string ; a owl:Class ; rdfs:label "keratoacanthoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_219, obo:MPATH_442 . obo:MPATH_445 obo:IAO_0000115 "A benign tumor consisting of villous or arborescent outgrowths of fibrovascular stroma covered by neoplastic epithelial cells (M-8050/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:445"^^xsd:string ; a owl:Class ; rdfs:label "papilloma"^^xsd:string ; rdfs:subClassOf obo:MPATH_264, obo:MPATH_556 . obo:MPATH_446 obo:IAO_0000115 "Malignant tumor derived from stratified squamous cells. (M-8070/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "carcinoma, epidermoid ( sensu epidermal derived tumors)"^^xsd:string ; oboInOwl:id "MPATH:446"^^xsd:string ; a owl:Class ; rdfs:label "squamous cell carcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_219, obo:MPATH_442, obo:MPATH_549 . obo:MPATH_447 obo:IAO_0000115 "Pre-neoplastic intraepithelial lesion of squamous cells (M-8070/2)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "IENIII"^^xsd:string, "severe intra-epithelial neoplasia"^^xsd:string ; oboInOwl:id "MPATH:447"^^xsd:string ; a owl:Class ; rdfs:label "squamous cell carcinoma in situ"^^xsd:string ; rdfs:subClassOf obo:MPATH_219, obo:MPATH_442, obo:MPATH_556 . obo:MPATH_448 obo:IAO_0000115 "A benign tumor consisting of villous or arborescent outgrowths of fibrovascular stroma covered by neoplastic squamous epithelial cells."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Exophytic papilloma"^^xsd:string ; oboInOwl:id "MPATH:448"^^xsd:string ; a owl:Class ; rdfs:label "squamous cell papilloma"^^xsd:string ; rdfs:subClassOf obo:MPATH_219, obo:MPATH_442, obo:MPATH_445 . obo:MPATH_449 obo:IAO_0000115 "A well-differentiated papillary squamous cell carcinoma. (M-8051/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:449"^^xsd:string ; a owl:Class ; rdfs:label "verrucous carcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_442, obo:MPATH_549 . obo:MPATH_45 obo:IAO_0000115 "Non-specified intra or extracellular deposition of protein."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:45"^^xsd:string ; a owl:Class ; rdfs:label "protein deposition"^^xsd:string ; rdfs:subClassOf obo:MPATH_33 . obo:MPATH_450 obo:IAO_0000115 "Neoplasms of transitional epithelia, eg kidney, ureter , bladder , cervix."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:450"^^xsd:string ; a owl:Class ; rdfs:label "transitional cell tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_218 . obo:MPATH_451 obo:IAO_0000115 "Malignant neoplasm of transitional cells (M-8120/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:451"^^xsd:string ; a owl:Class ; rdfs:label "transitional cell carcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_450, obo:MPATH_549 . obo:MPATH_452 obo:IAO_0000115 "Pre-malignant intra-epithelial neoplasm of transitional cells (M-8120/2)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "severe intra-epithelial neoplasia"^^xsd:string ; oboInOwl:id "MPATH:452"^^xsd:string ; a owl:Class ; rdfs:label "transitional cell carcinoma in situ"^^xsd:string ; rdfs:subClassOf obo:MPATH_450, obo:MPATH_556 . obo:MPATH_453 obo:IAO_0000115 "Pre-malignant lesion of transitional cells, papillomatous form ( M- 8120/1)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:453"^^xsd:string ; a owl:Class ; rdfs:label "transitional cell papilloma"^^xsd:string ; rdfs:subClassOf obo:MPATH_450 . obo:MPATH_454 obo:IAO_0000115 "Tumors derived directly from trophoblastic tissue or differentiated from germ cell tumor origins."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:454"^^xsd:string ; a owl:Class ; rdfs:label "trophoblastic tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_218 . obo:MPATH_455 obo:IAO_0000115 "Tumor derived from malignant trophoblastic cells. May be found in the uterus, ovary and testis. May also be derived from teratomas and teratocarcinomas in males. (M-9100/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Chorioepithelioma, malignant."^^xsd:string ; oboInOwl:id "MPATH:455"^^xsd:string ; a owl:Class ; rdfs:label "choriocarcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_310, obo:MPATH_454 . obo:MPATH_456 obo:IAO_0000115 "Vesicular or cystic tumor with hydropic villi resulting from the proliferation of trophoblast in the absence ( complete) or the presence ( partial) of an embryo. Most complete moles are homozygous androgenetic XX 46.(M-9100/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "cystic mole"^^xsd:string, "gestational trophoblastic disease"^^xsd:string ; oboInOwl:id "MPATH:456"^^xsd:string ; a owl:Class ; rdfs:label "hydatidiform mole"^^xsd:string ; rdfs:subClassOf obo:MPATH_454 . obo:MPATH_457 obo:IAO_0000115 "Neoplastic proliferation of intermediate trophoblasts that invades the myometrium at the placental site after a pregnancy. (M-9104/1)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:457"^^xsd:string ; a owl:Class ; rdfs:label "placental site trophoblastic tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_454 . obo:MPATH_458 obo:IAO_0000115 "No pathological entity observable."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:458"^^xsd:string ; a owl:Class ; rdfs:label "normal"^^xsd:string ; rdfs:subClassOf obo:MPATH_1000 . obo:MPATH_459 obo:IAO_0000115 "obsolete"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:459"^^xsd:string ; a owl:Class ; rdfs:label "obsolete"^^xsd:string ; owl:deprecated true . obo:MPATH_46 obo:IAO_0000115 "Extracellular deposition of uric acid crystals."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:46"^^xsd:string ; a owl:Class ; rdfs:label "uric acid deposition"^^xsd:string ; rdfs:subClassOf obo:MPATH_33 . obo:MPATH_460 obo:IAO_0000115 "Defect in the structure or function of the nuclear membrane or matrix or other component."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:460"^^xsd:string ; a owl:Class ; rdfs:label "nuclear defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_17 . obo:MPATH_461 obo:IAO_0000115 "Proliferation of lens epithelium and capsule leading to fibrous metaplasia and anterior subcapsular cataract ( ASC) . Possible developmental origin."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:461"^^xsd:string ; a owl:Class ; rdfs:label "cataract; capsular-epithelial"^^xsd:string ; rdfs:subClassOf obo:MPATH_29 . obo:MPATH_462 obo:IAO_0000115 "Nuclear cataract of developmental origin with tendency to progress with age and involve the cortex and capsule."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:462"^^xsd:string ; a owl:Class ; rdfs:label "cataract; nuclear and cortical"^^xsd:string ; rdfs:subClassOf obo:MPATH_29 . obo:MPATH_463 obo:IAO_0000115 "Of developmental origins; nucleus and cortex become completely liquefied in post-natal life."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:463"^^xsd:string ; a owl:Class ; rdfs:label "cataract; cortical liquefactive"^^xsd:string ; rdfs:subClassOf obo:MPATH_29 . obo:MPATH_464 obo:IAO_0000115 "Involves capsular rupture usually of the posterior lens capsule, close to birth or in the first few weeks postpartum. Cortical material spills into the vitreous humor and may be disseminated through the eye."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:464"^^xsd:string ; a owl:Class ; rdfs:label "cataract; lens extrusion"^^xsd:string ; rdfs:subClassOf obo:MPATH_29 . obo:MPATH_465 obo:IAO_0000115 "Consequent on developmental abnormalities in the trabecular network and Schlemm`s canal in the angle."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:465"^^xsd:string ; a owl:Class ; rdfs:label "glaucoma developmental"^^xsd:string ; rdfs:subClassOf obo:MPATH_32 . obo:MPATH_466 obo:IAO_0000115 "Failure of drainage of the eye for unknown reasons."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:466"^^xsd:string ; a owl:Class ; rdfs:label "glaucoma; open angle"^^xsd:string ; rdfs:subClassOf obo:MPATH_32 . obo:MPATH_467 obo:IAO_0000115 "Develops when the angle caused by the iris and cornea closes. May occur because of anatomically narrow angles or adhesions."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:467"^^xsd:string ; a owl:Class ; rdfs:label "glaucoma; angle closure"^^xsd:string ; rdfs:subClassOf obo:MPATH_32 . obo:MPATH_468 obo:IAO_0000115 "Formation of extracellular (sensu pancreas) non-epithelial bounded spaces containing accumulated products or substances."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:468"^^xsd:string ; a owl:Class ; rdfs:label "pseudocyst"^^xsd:string ; rdfs:subClassOf obo:MPATH_1 . obo:MPATH_469 obo:IAO_0000115 "Any aberration of the normal symmetrical organisation of the body pattern."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:469"^^xsd:string ; a owl:Class ; rdfs:label "symmetry defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_56 . obo:MPATH_47 obo:IAO_0000115 "Loss or dispersion of specific intra- and extracellular substances."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:47"^^xsd:string ; a owl:Class ; rdfs:label "intracellular and extracellular depletion"^^xsd:string ; rdfs:subClassOf obo:MPATH_1 . obo:MPATH_470 obo:IAO_0000115 "Left/Right (mediolateral) axis aberration of the normal symmetrical organisation of the body pattern."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:470"^^xsd:string ; a owl:Class ; rdfs:comment "For example as seen in the mutation ."^^xsd:string ; rdfs:label "left/right axis defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_469 . obo:MPATH_471 obo:IAO_0000115 "Anteroposterior aberration of the normal symmetrical organisation of the body pattern."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:471"^^xsd:string ; a owl:Class ; rdfs:label "anterior/posterior axis defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_469 . obo:MPATH_472 obo:IAO_0000115 "Dorsoventral aberration of the normal symmetrical organisation of the body pattern."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:472"^^xsd:string ; a owl:Class ; rdfs:label "dorsal/ventral axis defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_469 . obo:MPATH_473 obo:IAO_0000115 "Developmental dysplasia showing epithelial cell bounded cavities."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:473"^^xsd:string ; a owl:Class ; rdfs:label "developmental cystic dysplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_64 . obo:MPATH_474 obo:IAO_0000115 "Dilation of a tubular structure."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:474"^^xsd:string ; a owl:Class ; rdfs:comment "Often associated with an obstruction."^^xsd:string ; rdfs:label "ectasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_66 . obo:MPATH_475 obo:IAO_0000115 "Dilation of a ductal structure."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:475"^^xsd:string ; a owl:Class ; rdfs:label "ductal ectasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_474 . obo:MPATH_476 obo:IAO_0000115 "A lesion formed by a dilated capillary or terminal artery."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:476"^^xsd:string ; a owl:Class ; rdfs:label "telangiectasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_474 . obo:MPATH_477 obo:IAO_0000115 "Similar to hamartoma, including the mass lesion requirement, but unlike hamartoma, includes heterotopic tissue of an adult or embryonic nature ( topographical and developmental anomaly)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Choristoblastoma"^^xsd:string ; oboInOwl:id "MPATH:477"^^xsd:string ; a owl:Class ; rdfs:label "choristoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_56 . obo:MPATH_478 obo:IAO_0000115 "Abnormality in developmental angiogenesis."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:478"^^xsd:string ; a owl:Class ; rdfs:label "angiogenesis defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_599 . obo:MPATH_479 obo:IAO_0000115 "Defect in formation of blood vessels by vasculogenesis, proliferation or recruitment of endothelial cells."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:479"^^xsd:string ; a owl:Class ; rdfs:label "vasculogenesis defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_599 . obo:MPATH_48 obo:IAO_0000115 "Process of loss of calcium from normally calcified tissue, usually bone."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:48"^^xsd:string ; a owl:Class ; rdfs:label "decalcification"^^xsd:string ; rdfs:subClassOf obo:MPATH_47 . obo:MPATH_480 obo:IAO_0000115 "Any defect in the formation, architecture, cellular composition or function of the maternal decidua."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:480"^^xsd:string ; a owl:Class ; rdfs:label "decidual defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_100 . obo:MPATH_481 obo:IAO_0000115 "Lesions likely to result in progression to frank tumors, which may be classified as pre-neoplastic or pre-cancerous."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:481"^^xsd:string ; a owl:Class ; rdfs:comment "Obsolete; replaced by potentially pre-cancerous lesions (MPATH 556) as many are actually neoplastic but do not progress to cancer."^^xsd:string ; rdfs:label "pre-neoplastic lesions"^^xsd:string ; owl:deprecated true . obo:MPATH_482 obo:IAO_0000115 "Localised hyperplastic lesion. Polyclonal lesions are probably benign but clonal lesions may progress to malignancy."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:482"^^xsd:string ; a owl:Class ; rdfs:label "focal hyperplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_602 . obo:MPATH_483 obo:IAO_0000115 "Presence of localised areas within for example adenomas showing characteristics of neoplastic (tumor) progression, eg focal carcinoma."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:483"^^xsd:string ; a owl:Class ; rdfs:comment "Considered to be too vague to be useful."^^xsd:string ; rdfs:label "atypical hyperplasia"^^xsd:string ; owl:deprecated true . obo:MPATH_484 obo:IAO_0000115 "Expansion of small hyperplastic lesions to become macroscopically nodules, compressing adjacent cells."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "hyperplastic nodules"^^xsd:string, "nodular hyperplasia"^^xsd:string ; oboInOwl:id "MPATH:484"^^xsd:string ; a owl:Class ; rdfs:label "hyperplastic nodule"^^xsd:string ; rdfs:subClassOf obo:MPATH_602 . obo:MPATH_485 obo:IAO_0000115 "May be used in some systems in preference to its synonyms to indicate lesion specific aprearances. A lesion characterised by changes of the type associated with invasive carcinoma, but physically bounded by the lining epithelium and without local invasion."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "severe epithelial dysplasia"^^xsd:string, "severe intraepithelial neoplasia"^^xsd:string ; oboInOwl:id "MPATH:485"^^xsd:string ; a owl:Class ; rdfs:comment "Subsumed into MPATH: 132"^^xsd:string ; rdfs:label "carcinoma in situ"^^xsd:string ; owl:deprecated true . obo:MPATH_486 obo:IAO_0000115 "Pre-malignant hyperplastic and/or dysplastic change in the mammary gland epithelium with the potential to give rise to malignant tumors."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "DIN"^^xsd:string, "Ductal carcinoma in situ"^^xsd:string, "MIN"^^xsd:string, "intraductal adenocarcinoma, non-infiltrating"^^xsd:string, "mammary intra-epithelial neoplasia"^^xsd:string ; oboInOwl:id "MPATH:486"^^xsd:string ; a owl:Class ; rdfs:comment "This term covers the range of DIN (MIN) including severe intra-epithelial neoplasia (IENIII), alternatively termed in situ carcinoma of the mammary ductal epithelium. (M- 8500/2). See Tavassoli FA. (1998) Mod Pathol. 11:140-54. Ductal carcinoma in situ: introduction of the concept of ductal intraepithelial neoplasia for further definition."^^xsd:string ; rdfs:label "ductal intra-epithelial neoplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_267, obo:MPATH_556 . obo:MPATH_487 obo:IAO_0000115 "Histologically apparent areas of dysplasia that are not grossly visible (smaller than 0.5-1 mm). Lesions may involve single or multiple glands."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "GIN"^^xsd:string, "IIN"^^xsd:string, "microadenoma"^^xsd:string ; oboInOwl:id "MPATH:487"^^xsd:string ; a owl:Class ; rdfs:label "intestinal intra-epithelial neoplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_128 . obo:MPATH_488 obo:IAO_0000115 "See reference for definition."^^xsd:string ; oboInOwl:hasDbXref "URL: http://emice.nci.nih.gov/emice/mouse_models/organ_models/prostate_models/path_class_mouse"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "PIN"^^xsd:string ; oboInOwl:id "MPATH:488"^^xsd:string ; a owl:Class ; rdfs:label "prostate intra-epithelial neoplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_128 . obo:MPATH_489 obo:IAO_0000115 "stomach, oesophagus and pancreatic intra-epithelial neoplasia"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "PANIN"^^xsd:string ; oboInOwl:id "MPATH:489"^^xsd:string ; a owl:Class ; rdfs:label "stomach, oesophagus and pancreatic intra-epithelial neoplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_128 . obo:MPATH_49 obo:IAO_0000115 "Reduction of myelin content in neuronal sheath."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:49"^^xsd:string ; a owl:Class ; rdfs:label "demyelination"^^xsd:string ; rdfs:subClassOf obo:MPATH_47 . obo:MPATH_490 obo:IAO_0000115 "Benign neoplastic growth containing areas of adenomatous structure (progression)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "polypoid adenoma, cellular polyp."^^xsd:string ; oboInOwl:id "MPATH:490"^^xsd:string ; a owl:Class ; rdfs:label "adenomatous polyp"^^xsd:string ; rdfs:subClassOf obo:MPATH_270, [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:MPATH_271 ] . obo:MPATH_491 obo:IAO_0000115 "A mass of tissue which projects outward or upward from the normal surface level being macroscopically visible as a hemispheroidal, spheroidal, or irregular moundlike structure growing from a relatively broad base or a slender stalk."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:491"^^xsd:string ; a owl:Class ; rdfs:label "polyp"^^xsd:string ; rdfs:subClassOf obo:MPATH_138 . obo:MPATH_492 obo:IAO_0000115 "Glomerulonephritis characterized by diffuse thickening of glomerular capillary basement membranes, due in part to subepithelial deposits of immunoglobulins separated by spikes of basement membrane material,."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:492"^^xsd:string ; a owl:Class ; rdfs:label "membraneous glomerulonephritis"^^xsd:string ; rdfs:subClassOf obo:MPATH_197 . obo:MPATH_493 obo:IAO_0000115 "A chronic glomerulonephritis characterized by mesangial cell proliferation, increased lobular separation of glomeruli, thickening of glomerular capillary walls and increased mesangial matrix,."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:493"^^xsd:string ; a owl:Class ; rdfs:label "membraneoproliferative glomerulonephritis"^^xsd:string ; rdfs:subClassOf obo:MPATH_197 . obo:MPATH_494 obo:IAO_0000115 "Glomerulonephritis caused by autoimmune attack on the glomerulus."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:494"^^xsd:string ; a owl:Class ; rdfs:comment "Needs multiple parentage with autoimmune mediated disease"^^xsd:string ; rdfs:label "autoimmune glomerulonephritis"^^xsd:string ; rdfs:subClassOf obo:MPATH_197 . obo:MPATH_495 obo:IAO_0000115 "Tumor derived from the capillary glomus with arteriovenous capillary anastomoses. Often characterized by multiple tumors resembling cavernous hemangioma (M-8712/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:495"^^xsd:string ; a owl:Class ; rdfs:label "glomangioma"^^xsd:string ; rdfs:subClassOf obo:MPATH_235 . obo:MPATH_496 obo:IAO_0000115 "Neoplasms of non-lymphoid haematopoietic lineage. Must have at least 20% blast cells to meet this definition."^^xsd:string ; oboInOwl:hasDbXref "URL:http://www.bloodjournal.org/cgi/content/full/100/1/238/DC1/2"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:496"^^xsd:string ; a owl:Class ; rdfs:label "Non-Lymphoid leukaemias"^^xsd:string ; rdfs:subClassOf obo:MPATH_515 . obo:MPATH_497 obo:IAO_0000115 "Leukaemia in which neoplastic cells are poorly differentiated and not monocytic. At least 90% of the cells have to be blasts."^^xsd:string ; oboInOwl:hasDbXref "URL:http://www.bloodjournal.org/cgi/content/full/100/1/238/DC1/2"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "myeloblastic leukaemia without maturation"^^xsd:string, "myeloid leukaemia (myeloblastic type)"^^xsd:string, "poorly differentiated myeloid leukaemia"^^xsd:string ; oboInOwl:id "MPATH:497"^^xsd:string ; a owl:Class ; rdfs:label "myeloid leukaemia without maturation"^^xsd:string ; rdfs:subClassOf obo:MPATH_342 . obo:MPATH_498 obo:IAO_0000115 "Leukaemia in which neoplastic cells are moderately differentiated with a neutrophilic but not monocytic component. At least 20% of the cells have to be blasts."^^xsd:string ; oboInOwl:hasDbXref "URL:http://www.bloodjournal.org/cgi/content/full/100/1/238/DC1/2"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "myeloblastic laeukaemia with maturation"^^xsd:string, "poorly differentiated myeloid leukaemia"^^xsd:string ; oboInOwl:id "MPATH:498"^^xsd:string ; a owl:Class ; rdfs:label "myeloid leukaemia with maturation"^^xsd:string ; rdfs:subClassOf obo:MPATH_342 . obo:MPATH_499 obo:IAO_0000115 "Abnormal proliferation of beta cells of developing islets often leading to marked diffuse or focal beta-cell hyperplasia. Considered to generate a potentially cancerous lesion."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Beta-cell nesidioblastosis"^^xsd:string, "congenital insulinomas"^^xsd:string, "diffused or generalised islet cell hyperplasia"^^xsd:string, "endocrine dysplasia"^^xsd:string, "focal adenomatosis"^^xsd:string, "microadenomatosis"^^xsd:string, "multifocal and focal ductulo-insular proliferation (nesidioblastosis)"^^xsd:string, "nesidioblastoma"^^xsd:string, "nesidiodysplasia"^^xsd:string ; oboInOwl:id "MPATH:499"^^xsd:string ; a owl:Class ; rdfs:label "nesidioblastosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_64 . obo:MPATH_5 obo:IAO_0000115 "Area of liver necrosis that bridges adjacent portal areas and central veins."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:5"^^xsd:string ; a owl:Class ; rdfs:label "bridging necrosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_4 . obo:MPATH_50 obo:IAO_0000115 "Reduction in intracellular glycogen content."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:50"^^xsd:string ; a owl:Class ; rdfs:label "glycogen depletion"^^xsd:string ; rdfs:subClassOf obo:MPATH_47 . obo:MPATH_500 obo:IAO_0000115 "Leukaemia in which neoplastic cells are well differentiated and in which there are fewer than 20% blasts."^^xsd:string ; oboInOwl:hasDbXref "URL:http://www.bloodjournal.org/cgi/content/full/100/1/238/DC1/2"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "myeloid leukaemia, chonic type"^^xsd:string, "well differentiated myeloid leukaemia"^^xsd:string ; oboInOwl:id "MPATH:500"^^xsd:string ; a owl:Class ; rdfs:label "myeloproliferative disease-like myeloid leukaemia"^^xsd:string ; rdfs:subClassOf obo:MPATH_342 . obo:MPATH_501 obo:IAO_0000115 "Leukaemia in which neoplastic cells are moderately differentiated with a neutrophilic and a monocytic component. At least 20% of the cells have to be blasts."^^xsd:string ; oboInOwl:hasDbXref "URL:http://www.bloodjournal.org/cgi/content/full/100/1/238/DC1/2"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "myeloid leukaemia, myelomonocytic type"^^xsd:string ; oboInOwl:id "MPATH:501"^^xsd:string ; a owl:Class ; rdfs:label "myelomonocytic leukaemia"^^xsd:string ; rdfs:subClassOf obo:MPATH_342 . obo:MPATH_502 obo:IAO_0000115 "Leukaemia in which neoplastic cells are poorly or moderately differentiated with a monocytic but no neutrophilic component. At least 20% of the cells must be blasts."^^xsd:string ; oboInOwl:hasDbXref "URL:http://www.bloodjournal.org/cgi/content/full/100/1/238/DC1/2"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:502"^^xsd:string ; a owl:Class ; rdfs:label "monocytic leukaemia"^^xsd:string ; rdfs:subClassOf obo:MPATH_342 . obo:MPATH_503 obo:IAO_0000115 "A leukaemia with at least 90% blasts and differentiation markers of the myeloid and lymphoid lineage."^^xsd:string ; oboInOwl:hasDbXref "URL:http://www.bloodjournal.org/cgi/content/full/100/1/238/DC1/2"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:503"^^xsd:string ; a owl:Class ; rdfs:label "biphenotypic leukaemia"^^xsd:string ; rdfs:subClassOf obo:MPATH_496 . obo:MPATH_504 obo:IAO_0000115 "Solid tumor mass composed of non-lymphoid haematopoietic cells."^^xsd:string ; oboInOwl:hasDbXref "URL:http://www.bloodjournal.org/cgi/content/full/100/1/238/DC1/2"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:504"^^xsd:string ; a owl:Class ; rdfs:label "non-lymphoid hematopoietic sarcomas"^^xsd:string ; rdfs:subClassOf obo:MPATH_335, obo:MPATH_551 . obo:MPATH_505 obo:IAO_0000115 "Solid tumor mass composed predominantly of granulocytic or relatively undifferentiated non-lymphoid haematopoietic cells."^^xsd:string ; oboInOwl:hasDbXref "URL:http://www.bloodjournal.org/cgi/content/full/100/1/238/DC1/2"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:505"^^xsd:string ; a owl:Class ; rdfs:label "granulocytic sarcoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_504 . obo:MPATH_506 obo:IAO_0000115 "Solid tumor mass composed predominantly of histiocytic cells (M-9775/3)."^^xsd:string ; oboInOwl:hasDbXref "URL:http://www.bloodjournal.org/cgi/content/full/100/1/238/DC1/2"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Kupffer cell sarcoma (sensu liver)"^^xsd:string, "histiocytic lymphoma"^^xsd:string, "malignant lymphoma, histiocytic type"^^xsd:string, "reticulum cell sarcoma, type A"^^xsd:string, "reticulum cell sarcoma, type A, reticulosarcoma"^^xsd:string ; oboInOwl:id "MPATH:506"^^xsd:string ; a owl:Class ; rdfs:label "histiocytic sarcoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_504 . obo:MPATH_507 obo:IAO_0000115 "Solid tumor mass composed of mast cells."^^xsd:string ; oboInOwl:hasDbXref "URL:http://www.bloodjournal.org/cgi/content/full/100/1/238/DC1/2"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "malignant mastocytoma"^^xsd:string, "mast cell tumor"^^xsd:string, "mastocytosis"^^xsd:string ; oboInOwl:id "MPATH:507"^^xsd:string ; a owl:Class ; rdfs:label "mast cell sarcoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_504 . obo:MPATH_508 obo:IAO_0000115 "Haematopoietic proliferation with evidence of trilineage dysplasia."^^xsd:string ; oboInOwl:hasDbXref "URL:http://www.bloodjournal.org/cgi/content/full/100/1/238/DC1/2"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:508"^^xsd:string ; a owl:Class ; rdfs:label "myeloid dysplasias"^^xsd:string ; rdfs:subClassOf obo:MPATH_515 . obo:MPATH_509 obo:IAO_0000115 "Haematopoietic proliferation with evidence of trilineage dysplasia. More than 20% should be blasts."^^xsd:string ; oboInOwl:hasDbXref "URL:http://www.bloodjournal.org/cgi/content/full/100/1/238/DC1/2"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:509"^^xsd:string ; a owl:Class ; rdfs:label "cytopenia with increased blasts"^^xsd:string ; rdfs:subClassOf obo:MPATH_508 . obo:MPATH_51 obo:IAO_0000115 "Intrinsic abnormally low level of calcification in a tissue cf. MPATH: 48."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:51"^^xsd:string ; a owl:Class ; rdfs:label "hypocalcification"^^xsd:string ; rdfs:subClassOf obo:MPATH_47 . obo:MPATH_510 obo:IAO_0000115 "Non-reactive persistent accumulation of non-lymphoid haematopoietic cells. Genetically determined."^^xsd:string ; oboInOwl:hasDbXref "URL:http://www.bloodjournal.org/cgi/content/full/100/1/238/DC1/2"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:510"^^xsd:string ; a owl:Class ; rdfs:label "myeloid proliferations (non-reactive)"^^xsd:string ; rdfs:subClassOf obo:MPATH_515 . obo:MPATH_511 obo:IAO_0000115 "Non-reactive persistent accumulation of non-lymphoid haematopoietic cells in the blood which do not infiltrate the spleen and the bone marrow. Genetically determined."^^xsd:string ; oboInOwl:hasDbXref "URL:http://www.bloodjournal.org/cgi/content/full/100/1/238/DC1/2"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:511"^^xsd:string ; a owl:Class ; rdfs:label "myeloproliferation (genetic)"^^xsd:string ; rdfs:subClassOf obo:MPATH_510 . obo:MPATH_512 obo:IAO_0000115 "Non-reactive persistent accumulation of non-lymphoid haematopoietic cells in the blood which infiltrate the spleen and the bone marrow."^^xsd:string ; oboInOwl:hasDbXref "URL:http://www.bloodjournal.org/cgi/content/full/100/1/238/DC1/2"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:512"^^xsd:string ; a owl:Class ; rdfs:label "myeloproliferative disease"^^xsd:string ; rdfs:subClassOf obo:MPATH_510 . obo:MPATH_513 obo:IAO_0000115 "Neoplasms of the B or T cell lineage."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:513"^^xsd:string ; a owl:Class ; rdfs:label "lymphoid neoplasms"^^xsd:string ; rdfs:subClassOf obo:MPATH_335 . obo:MPATH_514 obo:IAO_0000115 "B cell neoplasms"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:514"^^xsd:string ; a owl:Class ; rdfs:label "B cell neoplasms"^^xsd:string ; owl:deprecated true . obo:MPATH_515 obo:IAO_0000115 "Hematological neoplasias of non-lymphoid origin."^^xsd:string ; oboInOwl:hasDbXref "URL:http://www.bloodjournal.org/cgi/content/full/100/1/238/DC1/2"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:515"^^xsd:string ; a owl:Class ; rdfs:label "non-Lymphoid neoplasias"^^xsd:string ; rdfs:subClassOf obo:MPATH_335 . obo:MPATH_516 obo:IAO_0000115 "Neoplasm of the B cell lymphoid lineage."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:516"^^xsd:string ; a owl:Class ; rdfs:label "B-cell neoplasms"^^xsd:string ; rdfs:subClassOf obo:MPATH_513 . obo:MPATH_517 obo:IAO_0000115 "Lymphoma originating from precursor B-cells."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:517"^^xsd:string ; a owl:Class ; rdfs:label "precursor B cell neoplasms"^^xsd:string ; rdfs:subClassOf obo:MPATH_516 . obo:MPATH_518 obo:IAO_0000115 "Lymphoma originating in a precursor B-cell."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "lymphoblastic leukaemia"^^xsd:string, "lymphoblastic lymphoma"^^xsd:string ; oboInOwl:id "MPATH:518"^^xsd:string ; a owl:Class ; rdfs:label "precursor B -cell lymphoblastic lymphoma/leukaemia"^^xsd:string ; rdfs:subClassOf obo:MPATH_517 . obo:MPATH_519 obo:IAO_0000115 "Lymphomas originating in peripheral B cells."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:519"^^xsd:string ; a owl:Class ; rdfs:label "mature B-cell neoplasms"^^xsd:string ; rdfs:subClassOf obo:MPATH_516 . obo:MPATH_52 obo:IAO_0000115 "Reduction in cellular or plasma lipid content."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:52"^^xsd:string ; a owl:Class ; rdfs:label "lipid depletion"^^xsd:string ; rdfs:subClassOf obo:MPATH_47 . obo:MPATH_520 obo:IAO_0000115 "Diffuse accumulation of small mature B-cells."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "small lymphocytic lymphoma"^^xsd:string, "well differentiated lymphocytic lymphoma"^^xsd:string ; oboInOwl:id "MPATH:520"^^xsd:string ; a owl:Class ; rdfs:label "small B-cell lymphoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_519 . obo:MPATH_521 obo:IAO_0000115 "A lymphoid proliferation of cells of the marginal zone of the white pulp of the spleen."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "SMZL"^^xsd:string ; oboInOwl:id "MPATH:521"^^xsd:string ; a owl:Class ; rdfs:label "splenic marginal zone lymphoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_519 . obo:MPATH_522 obo:IAO_0000115 "A lymphoid proliferation composed of a mixture of centroblasts and centrocytes that may or may not have a nodular(follicular)pattern. The follicular dendritic cell network is not present, unlike in the human. The equivalent typical translocation (Chr. 14:18 )seen in humans has not been reported in the mouse."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "centroblastic/centrocytic lymphoma"^^xsd:string, "follicular center cell lymphoma, small cell or mixed"^^xsd:string, "follicular lymphoma"^^xsd:string ; oboInOwl:id "MPATH:522"^^xsd:string ; a owl:Class ; rdfs:label "follicular B cell lymphoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_519 . obo:MPATH_523 obo:IAO_0000115 "Diffuse proliferation of large B lymphoid cells."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "DLBCL"^^xsd:string ; oboInOwl:id "MPATH:523"^^xsd:string ; a owl:Class ; rdfs:label "diffuse large B-cell lymphoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_519 . obo:MPATH_524 obo:IAO_0000115 "Diffuse follicular centre cell lymphoma mainly composed of centroblasts."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "centroblastic lymphoma"^^xsd:string ; oboInOwl:id "MPATH:524"^^xsd:string ; a owl:Class ; rdfs:label "diffuse large B-cell lymphoma, centroblastic type"^^xsd:string ; rdfs:subClassOf obo:MPATH_523 . obo:MPATH_525 obo:IAO_0000115 "Diffuse large B cell lymphoma with increased number of immunoblasts."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Immunoblastic lymphoma"^^xsd:string ; oboInOwl:id "MPATH:525"^^xsd:string ; a owl:Class ; rdfs:label "diffuse large B-cell lymphoma, immunoblastic type"^^xsd:string ; rdfs:subClassOf obo:MPATH_523 . obo:MPATH_526 obo:IAO_0000115 "Diffuse large B-cell lymphoma with more than 50% histiocytes."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "DLCL (HS)"^^xsd:string ; oboInOwl:id "MPATH:526"^^xsd:string ; a owl:Class ; rdfs:label "diffuse large B-cell lymphoma, histiocyte associated"^^xsd:string ; rdfs:subClassOf obo:MPATH_523 . obo:MPATH_527 obo:IAO_0000115 "Primary B-cell lymphoma of the thymus. Reported in C57BL/6 mice infected with replication defective MuLV. Not clear that this is the equivalent of the human disease."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:527"^^xsd:string ; a owl:Class ; rdfs:label "primary mediastinal (thymic) diffuse large B cell lymphoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_523 . obo:MPATH_528 obo:IAO_0000115 "Highly proliferative B-cell lymphoma characteristically seen in c-Myc transgenic mice, derived from mature B cells."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:528"^^xsd:string ; a owl:Class ; rdfs:label "classic Burkitt lymphoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_519 . obo:MPATH_529 obo:IAO_0000115 "Highly proliferative mature B-cell lymphoma, poorly defined."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:529"^^xsd:string ; a owl:Class ; rdfs:label "Burkitt-like lymphoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_519 . obo:MPATH_53 obo:IAO_0000115 "Reduced bone mass due to inadequate synthesis of osteoid, resulting in decreased calcification."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:53"^^xsd:string ; a owl:Class ; rdfs:label "osteopenia"^^xsd:string ; rdfs:subClassOf obo:MPATH_47 . obo:MPATH_530 obo:IAO_0000115 "Diffuse proliferation of mature plasma cells. Clonal by definition. Includes the equivalent of human myeloma (ICD-O 9732/3)."^^xsd:string ; oboInOwl:hasDbXref "URL: http://emice.nci.nih.gov/emice/mouse_models/organ_models/hema_models/hema_mouse_class"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Myeloma ( human )"^^xsd:string ; oboInOwl:id "MPATH:530"^^xsd:string ; a owl:Class ; rdfs:label "plasma cell neoplasms"^^xsd:string ; rdfs:subClassOf obo:MPATH_516 . obo:MPATH_531 obo:IAO_0000115 "Unusual lymphoma type described in thymectomised (SL/Kh x AKR/Ms) F1 mice. No equivalent found in human to date. See reference for detailed phenotype."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:531"^^xsd:string ; a owl:Class ; rdfs:label "B-natural killer cell lymphoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_516 . obo:MPATH_532 obo:IAO_0000115 "Diffuse proliferation of mature plasma cells. Clonal by definition."^^xsd:string ; oboInOwl:hasDbXref "URL: http://emice.nci.nih.gov/emice/mouse_models/organ_models/hema_models/hema_mouse_class"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:532"^^xsd:string ; a owl:Class ; rdfs:comment "Tissue, usually lymph nodes, that contain unusually large numbers of normal appearing plasma cells. While these may be plasmacytomas, additional work is needed to confirm this latter diagnosis."^^xsd:string ; rdfs:label "plasmacytoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_530 . obo:MPATH_533 obo:IAO_0000115 "Diffuse proliferation of mature plasma cells. Clonal by definition. Frequently found in IL6 transgenic mice. Characteristically involves spleen and nodes rather than peritoneum."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:533"^^xsd:string ; a owl:Class ; rdfs:label "extraosseous plasmacytoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_532 . obo:MPATH_534 obo:IAO_0000115 "Diffuse proliferation of immature plasma cells or plasma blasts."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:534"^^xsd:string ; a owl:Class ; rdfs:label "anaplastic plasmacytoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_532 . obo:MPATH_535 obo:IAO_0000115 "Neoplasms derived from cells of the T lymphocyte lineage."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:535"^^xsd:string ; a owl:Class ; rdfs:label "T-cell neoplasms"^^xsd:string ; rdfs:subClassOf obo:MPATH_513 . obo:MPATH_536 obo:IAO_0000115 "Neoplasms of precursor T cells."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:536"^^xsd:string ; a owl:Class ; rdfs:label "precursor T-cell neoplasms"^^xsd:string ; rdfs:subClassOf obo:MPATH_535 . obo:MPATH_537 obo:IAO_0000115 "Precursor T cell derived neoplasia. Most commonly found in the thymus."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "thymic lymphoma"^^xsd:string ; oboInOwl:id "MPATH:537"^^xsd:string ; a owl:Class ; rdfs:label "precursor T-cell lymphoblastic lymphoma/leukaemia"^^xsd:string ; rdfs:subClassOf obo:MPATH_536 . obo:MPATH_538 obo:IAO_0000115 "Non-thymic neoplasms of mature T cell origin."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:538"^^xsd:string ; a owl:Class ; rdfs:label "mature T-cell neoplasms"^^xsd:string ; rdfs:subClassOf obo:MPATH_535 . obo:MPATH_539 obo:IAO_0000115 "Accumulation of small mature T cells. No human counterpart known to date."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:539"^^xsd:string ; a owl:Class ; rdfs:label "small T-cell lymphoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_538 . obo:MPATH_54 obo:IAO_0000115 "Reduction in the quantity of bone or atrophy of skeletal tissue. More severe than MPATH: 53 with gross changes to bone matrix."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:54"^^xsd:string ; a owl:Class ; rdfs:label "osteoporosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_47 . obo:MPATH_540 obo:IAO_0000115 "T cell neoplasms which cannot currently be classified into known subtypes."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:540"^^xsd:string ; a owl:Class ; rdfs:label "T cell neoplasms character undetermined"^^xsd:string ; rdfs:subClassOf obo:MPATH_535 . obo:MPATH_541 obo:IAO_0000115 "Diffuse large pleiomorphic T cell lymphoma. This entity does not correspond to human anaplastic large cell lymphoma."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:541"^^xsd:string ; a owl:Class ; rdfs:label "T large cell anaplastic lymphoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_540 . obo:MPATH_542 obo:IAO_0000115 "Neoplasm of large granular T cells of CD8 phenotype."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:542"^^xsd:string ; a owl:Class ; rdfs:label "T natural killer cell lymphoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_535 . obo:MPATH_543 obo:IAO_0000115 "Benign neoplasm of the biliary duct. Occurs in solid and cystic forms. (M-8160/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:543"^^xsd:string ; a owl:Class ; rdfs:label "cholangioma"^^xsd:string ; rdfs:subClassOf obo:MPATH_352 . obo:MPATH_544 obo:IAO_0000115 "Benign tumor of unknown origin showing features of hepatocelluar adenoma and cholangioma."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:544"^^xsd:string ; a owl:Class ; rdfs:label "hepatocholangiocellular adenoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_254, obo:MPATH_270, obo:MPATH_352 . obo:MPATH_545 obo:IAO_0000115 "Malignant tumor of unknown origin showing features of hepatocelluar carcinoma and cholangiocarcinoma. (M-8180/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:545"^^xsd:string ; a owl:Class ; rdfs:label "hepatocholangiocellular carcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_254, obo:MPATH_352, obo:MPATH_549 . obo:MPATH_546 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-03-22T03:07:49Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:546"^^xsd:string ; a owl:Class ; rdfs:label "blepharitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_547 obo:IAO_0000115 "Extracellular accumulation of mucous secretions."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:547"^^xsd:string ; a owl:Class ; rdfs:comment "Mucus is the clear viscous secretion of the mucous membranes. Consisting of mucin, epithelial cells, leukocytes and various inorganic salts dissolved in water."^^xsd:string ; rdfs:label "mucous secretions"^^xsd:string ; rdfs:subClassOf obo:MPATH_33 . obo:MPATH_548 obo:IAO_0000115 "A generally malignant neoplasm consisting of villous or arborescent outgrowths of fibrovascular stroma covered by atypical neoplastic epithelial or urothelial cells cells."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:548"^^xsd:string ; a owl:Class ; rdfs:label "papillary transitional cell carcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_264, obo:MPATH_450 . obo:MPATH_549 obo:IAO_0000115 "Any of various types of malignant neoplasm derived from epithelial cells, chiefly glandular (adenocarcinoma) or squamous (squamous cell carcinoma)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:549"^^xsd:string ; a owl:Class ; rdfs:label "carcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_218 . obo:MPATH_55 obo:IAO_0000115 "Developmental and structural abnormalities occurring during embryonic development or during adult life."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:55"^^xsd:string ; a owl:Class ; rdfs:label "developmental and structural abnormality"^^xsd:string ; rdfs:subClassOf obo:MPATH_603 . obo:MPATH_550 obo:IAO_0000115 "A connective tissue neoplasm, usually highly malignant, formed by proliferation of mesodermal cells."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:550"^^xsd:string ; a owl:Class ; rdfs:label "sarcoma"^^xsd:string ; owl:deprecated true . obo:MPATH_551 obo:IAO_0000115 "A connective tissue neoplasm, usually highly malignant, formed by proliferation of mesodermal cells."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:551"^^xsd:string ; a owl:Class ; rdfs:label "sarcoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_218 . obo:MPATH_552 obo:IAO_0000115 "Benign tumor of the Clara cells of the bronchioalveolar epithelium."^^xsd:string ; oboInOwl:hasDbXref "URL: http://emice.nci.nih.gov/mouse_models/organ_models/lung_models/murinecancer/tumorclass"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:552"^^xsd:string ; a owl:Class ; rdfs:comment "Merged with MPATH:272 following recommendations of MMHC 2003."^^xsd:string ; rdfs:label "Clara cell adenoma"^^xsd:string ; owl:deprecated true . obo:MPATH_553 obo:IAO_0000115 "Inflammation of a nerve."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:553"^^xsd:string ; a owl:Class ; rdfs:label "neuritis"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_554 obo:IAO_0000115 "Regressive changes which may increase in severity, and which may result from defective nutrition or support of a tissue or organ."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:554"^^xsd:string ; a owl:Class ; rdfs:comment "Most often used for diseases in which a structure does not develop properly (not necessarily in an embryonic context) and undergoes degradation."^^xsd:string ; rdfs:label "dystrophy"^^xsd:string ; rdfs:subClassOf obo:MPATH_14 . obo:MPATH_555 obo:IAO_0000115 "Deposition of any homogeneous inorganic material."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:555"^^xsd:string ; a owl:Class ; rdfs:label "mineralisation"^^xsd:string ; rdfs:subClassOf obo:MPATH_33 . obo:MPATH_556 obo:IAO_0000115 "Lesions which in some cases have the potential to become progressively growing malignant tumors."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:556"^^xsd:string ; a owl:Class ; rdfs:label "potentially cancerous lesions"^^xsd:string ; rdfs:subClassOf obo:MPATH_218 . obo:MPATH_557 obo:IAO_0000115 "Sensu gastrointsestinal tract. visible microscopically in whole mount colonic tissue. One or more crypts larger than most, have a thickened layer of epithelial cells that stain more intensely with methylene blue. Some have a slit shaped luminal opening, and increased pericryptal space and are elevated from the focal plane of the microscope. ACF is not a histologic diagnosis."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "ACF"^^xsd:string ; oboInOwl:id "MPATH:557"^^xsd:string ; a owl:Class ; rdfs:comment "Use IEN1 MPATH:130 instead. Suppressed as not strictly a histological diagnosis."^^xsd:string ; rdfs:label "aberrant crypt foci"^^xsd:string ; owl:deprecated true . obo:MPATH_558 obo:IAO_0000115 "Adenocarcinoma type tumor with both glandular and squamous differentiation. (M-8983/0)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:558"^^xsd:string ; a owl:Class ; rdfs:label "adenomyoepithelioma"^^xsd:string ; rdfs:subClassOf obo:MPATH_254 . obo:MPATH_559 obo:IAO_0000115 "Tumor composed of small glandular clusters with small lumens."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:559"^^xsd:string ; a owl:Class ; rdfs:label "acinar adenocarcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_268 . obo:MPATH_56 obo:IAO_0000115 "Structural, physical or other general defect of prenatal development of the embryo and the placenta, or such as are acquired in the adult."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:56"^^xsd:string ; a owl:Class ; rdfs:label "developmental or adult structural defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_55 . obo:MPATH_560 obo:IAO_0000115 "Tumor composed of sheets or nests of cells forming lumens with round, punched out spaces."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:560"^^xsd:string ; a owl:Class ; rdfs:label "cribriform adenocarcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_268 . obo:MPATH_561 obo:IAO_0000115 "Mixed adeno- and squamous cell carcinoma. Not yet reported in mice. M-8560/3."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:561"^^xsd:string ; a owl:Class ; rdfs:label "adenosquamous carcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_268, obo:MPATH_442 . obo:MPATH_562 obo:IAO_0000115 "The twisting of a bodily organ or part on its own axis."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:562"^^xsd:string ; a owl:Class ; rdfs:label "torsion"^^xsd:string ; rdfs:subClassOf obo:MPATH_56 . obo:MPATH_563 obo:IAO_0000115 "carcinoma derived from gastrointestinal epithelium with a high mucinous content. (M-8480/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "mucinous adenocarcinoma"^^xsd:string ; oboInOwl:id "MPATH:563"^^xsd:string ; a owl:Class ; rdfs:label "mucinous carcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_268 . obo:MPATH_564 obo:IAO_0000115 "Develop primarily through increasing anaplasia of well differentiated gliomas, mainly astrocytomas or oligodendrogliomas. Typically large and contain cells of different sizes with irrregular nuclei and atypical mitotic figures. (M-9440/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "glioblastoma multiforme"^^xsd:string, "monstrocytoma"^^xsd:string ; oboInOwl:id "MPATH:564"^^xsd:string ; a owl:Class ; rdfs:comment "Also see Weiss, W.W, Israel, M. Cobbs, C., et al. (2002) Oncogene 21, 7453-7463."^^xsd:string ; rdfs:label "glioblastoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_249 . obo:MPATH_565 obo:IAO_0000115 "Tumors of neuronal and non-neuronal cells derived from embryonic neurepithelium."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:565"^^xsd:string ; a owl:Class ; rdfs:label "tumors of neurepithelial tissue"^^xsd:string ; rdfs:subClassOf obo:MPATH_243 . obo:MPATH_566 obo:IAO_0000115 "tumors of the meninges"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:566"^^xsd:string ; a owl:Class ; rdfs:label "tumors of the meninges"^^xsd:string ; rdfs:subClassOf obo:MPATH_243 . obo:MPATH_567 obo:IAO_0000115 "Glial cell derived tumor composed of bipolar cells with long `hairlike` GFAP-positive processes. (M9421/1)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "cystic cerebellar astrocytoma"^^xsd:string ; oboInOwl:id "MPATH:567"^^xsd:string ; a owl:Class ; rdfs:comment "Often cystic in children and generally considered benign."^^xsd:string ; rdfs:label "pilocytic astrocytoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_244 . obo:MPATH_568 obo:IAO_0000115 "Mixed tumor containing astrocytes within an oligodendroglioma or vice versa. In some cases both components may be neoplastic. (M-9382/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:568"^^xsd:string ; a owl:Class ; rdfs:comment "Also see Weiss, W.W, Israel, M. Cobbs, C., et al. (2002) Oncogene 21, 7453-7463."^^xsd:string ; rdfs:label "mixed glioma"^^xsd:string ; rdfs:subClassOf obo:MPATH_249, obo:MPATH_254 . obo:MPATH_569 obo:IAO_0000115 "granular cell tumor"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:569"^^xsd:string ; a owl:Class ; rdfs:comment "Subsumed into MP:413 as incidence in meninges, whilst a characteristic lesion, is the same type of tumor as that originally classified under myomatous tumors. Describe meningeal granular cell tumor using MP:413 and the anatomical descriptor."^^xsd:string ; rdfs:label "granular cell tumor"^^xsd:string ; owl:deprecated true . obo:MPATH_57 obo:IAO_0000115 "Failure of a tissue or organ to develop."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Agenesia"^^xsd:string ; oboInOwl:id "MPATH:57"^^xsd:string ; a owl:Class ; rdfs:label "agenesis"^^xsd:string ; rdfs:subClassOf obo:MPATH_599 . obo:MPATH_570 obo:IAO_0000115 "Tumors of the peripheral nervous system."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:570"^^xsd:string ; a owl:Class ; rdfs:label "peripheral nervous system tumors"^^xsd:string ; rdfs:subClassOf obo:MPATH_218 . obo:MPATH_571 obo:IAO_0000115 "Tumor composed of the epithelial components of the most proximal (trichogenic) portion of the hair follicle associated with an aberrent hair cortex type of cornification (ghost cells or shadow cells). The most primitive cellular component consists of basophilic cells having scanty cytoplasm and nuclei that occasionally overlap to some extent. In humans mineralisation is common."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:571"^^xsd:string ; a owl:Class ; rdfs:label "pilomatricoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_575 . obo:MPATH_572 obo:IAO_0000115 "Ossifying fibromas are benign tumors derived from pluripotential mesenchymal stem cells or osteoblasts. Occur spontaneously or in response to radiation. Preferentially located in mandible, maxilla and caudal spine. Composed of a characteristically regular trabecular bone pattern embedded in a fibrous stroma. Proliferating component consists of spindle cells which give rise to cuboidal osteoblasts to form rounded bodies or trabeculae. Bone trabeculae resemble the alphabet soup shapes characteristic of fibrous dysplasia in humans. In contrast to fibrous dysplasia the bone trabeculae of ossifying fibroma are mostly lamellar and ringed by active osteoblasts."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:572"^^xsd:string ; a owl:Class ; rdfs:label "ossifying fibroma"^^xsd:string ; rdfs:subClassOf obo:MPATH_388 . obo:MPATH_573 obo:IAO_0000115 "Pre-malignant lesion of transitional cells, papillomatous form, in which proliferating epithelium is invaginated beneath the surface."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:573"^^xsd:string ; a owl:Class ; rdfs:label "inverted transitional cell papilloma"^^xsd:string ; rdfs:subClassOf obo:MPATH_453 . obo:MPATH_574 obo:IAO_0000115 "Persistence of metanephrogenic blastema or its presence in the wrong place or at the wrong time. Associated with hyperplastic nephrogenic rests."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:574"^^xsd:string ; a owl:Class ; rdfs:label "nephroblastomatosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_64 . obo:MPATH_575 obo:IAO_0000115 "This is a new diagnostic term that the MMHC pathology panel felt best described a diagnostically challenging set of tumors that share the feature of being compose of basaloid cells showing follicular differentiation to some extent. These tumors are common in GEM involving the hedgehog signaling pathway and frequently have more than one of the histologic patterns listed below. The designation of benign and malignant has been excluded from the primary diagnosis purposely, as this is frequently difficult to determine in these characteristically well circumscribed tumors. The presence of a disorganized (non-palisaded) sheet-like growth pattern, tumor necrosis, or numerous mitoses are felt to represent malignant transformation."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:575"^^xsd:string ; a owl:Class ; rdfs:label "basaloid follicular neoplasms"^^xsd:string ; rdfs:subClassOf obo:MPATH_219 . obo:MPATH_576 obo:IAO_0000115 "Basaloid neoplasm with numerous mature hair follicles and hair formation."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:576"^^xsd:string ; a owl:Class ; rdfs:label "trichofolliculoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_575, [ a owl:Restriction ; owl:onProperty ; owl:someValuesFrom obo:MPATH_575 ] . obo:MPATH_577 obo:IAO_0000115 "Cellular neoplasm with well formed palisades of basaloid cells adjacent to less basophilic smaller cells with occasional central deposition of amorphous eosinophilic material. These tumors share some features with cylindroma type tumors but have a less well developed jigsaw puzzle-like architecture and tend to be more cellular."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:577"^^xsd:string ; a owl:Class ; rdfs:label "spiradenoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_575 . obo:MPATH_578 obo:IAO_0000115 "Basaloid neoplasm with frequent primitive hair follicles."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:578"^^xsd:string ; a owl:Class ; rdfs:label "trichoblastoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_575 . obo:MPATH_579 obo:IAO_0000115 "Loss of epithelium and the basement membrane (full thickness). Cf Erosion."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:579"^^xsd:string ; a owl:Class ; rdfs:label "ulcer"^^xsd:string ; rdfs:subClassOf obo:MPATH_1 . obo:MPATH_58 obo:IAO_0000115 "Absence of an organ or tissue coupled with persistence of the organ/tissue primordium, which fails to develop completely."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:58"^^xsd:string ; a owl:Class ; rdfs:label "aplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_599 . obo:MPATH_580 obo:IAO_0000115 "Partial epithelial denudation not penetrating to the basement membrane."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:580"^^xsd:string ; a owl:Class ; rdfs:label "erosion"^^xsd:string ; rdfs:subClassOf obo:MPATH_15 . obo:MPATH_581 obo:IAO_0000115 "Connective tissue proliferative reaction induced by a neoplastic process."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "scirrhous"^^xsd:string, "sclerosis"^^xsd:string ; oboInOwl:id "MPATH:581"^^xsd:string ; a owl:Class ; rdfs:label "desmoplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_604 . obo:MPATH_582 obo:IAO_0000115 "Scarring of the hair follicle without affecting the adjacent dermis. Pigment may be associated with fibrous tract in pigmented individuals."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:582"^^xsd:string ; a owl:Class ; rdfs:label "cicatricial alopecia"^^xsd:string ; rdfs:subClassOf obo:MPATH_26 . obo:MPATH_583 obo:IAO_0000115 "Loss of hair follicles in a diffuse dermal scar."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:583"^^xsd:string ; a owl:Class ; rdfs:label "scarring alopecia"^^xsd:string ; rdfs:subClassOf obo:MPATH_26 . obo:MPATH_584 obo:IAO_0000115 "In mice the term refers to accumulation of fibrous connective tissue in the medullary cavity of bones; usually in old mice. In humans the term is synonymous with myeloid metaplasia."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:584"^^xsd:string ; a owl:Class ; rdfs:label "myelofibrosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_25 . obo:MPATH_585 obo:IAO_0000115 "A mixed inflammatory infiltrate in the pulmonary airways with predominant intra-alveolar macrophage component with intra- and extracellular, elongated, bright eosinophilic/acidophilic crystals."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:585"^^xsd:string ; a owl:Class ; rdfs:comment "Crystals and acidophilic material have been reported as various materials including Ym1 and Ym2 proteins and blood pigment derivatives and Eotaxin."^^xsd:string ; rdfs:label "acidophilic macrophage pneumonia"^^xsd:string ; rdfs:subClassOf obo:MPATH_877 . obo:MPATH_586 obo:IAO_0000115 "A group of degenerative disorders resulting in multiple cysts in tissues."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "polycystic kidney disease"^^xsd:string, "polycystic liver disease"^^xsd:string, "polycystic ovary"^^xsd:string ; oboInOwl:id "MPATH:586"^^xsd:string ; a owl:Class ; rdfs:label "polycystic disease"^^xsd:string ; rdfs:subClassOf obo:MPATH_25 . obo:MPATH_587 obo:IAO_0000115 "The lesion is characterized microscopically by epithelial cells with atypical hyperchromatic nuclei, vacuolization, intratubular lumina formation, infrequent apoptosis, and rare mitotic figures. In contrast to germ cells, the cells of CEH do not express alpha-fetoprotein, carcinoembryonic antigen, or S-100. Ultrastructurally, the cells are pleomorphic with stereocilia at their apical borders and within intratubular lumina, and are supported by a basement membrane. CEH does not appear to be a preneoplastic change."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:587"^^xsd:string ; a owl:Class ; rdfs:comment "Cribriform epididymal hyperplasia was initially described as an incidental finding in human orchidectomy specimens. Recently, this condition was also described in mice, homozygous for a targeted mutation in p53."^^xsd:string ; rdfs:label "Cribriform epididymal hyperplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_602 . obo:MPATH_588 obo:IAO_0000115 "Dysplasia"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:588"^^xsd:string ; a owl:Class ; rdfs:label "dysplasia"^^xsd:string ; owl:deprecated true . obo:MPATH_589 obo:IAO_0000115 "Distortion or deficiency of the tissue or cellular architecture."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:589"^^xsd:string ; a owl:Class ; rdfs:comment "Note that with respect to developmental processes the term dysplasia is often used with greater specificity to describe aberrant developmental processes of proliferation and differentation, in which case MPATH: 64 Developmental dysplasia should be used."^^xsd:string ; rdfs:label "dysplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_604 . obo:MPATH_59 obo:IAO_0000115 "Defect in the process determining number, angle, pattern or rate of branching of tubular branched structures eg. Glandular ducts."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:59"^^xsd:string ; a owl:Class ; rdfs:label "defective branching morphogenesis"^^xsd:string ; rdfs:subClassOf obo:MPATH_599 . obo:MPATH_590 obo:IAO_0000115 "Lesion of bone showing accelerated osteoclastic bone resorption coupled with fibroplasia. Later stages show proliferation of osteoblasts."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "fibrous dysplasia"^^xsd:string, "fibrous osteodystrophy"^^xsd:string, "osteodysplasia"^^xsd:string, "osteodystrophy"^^xsd:string, "osteofibrosis"^^xsd:string ; oboInOwl:id "MPATH:590"^^xsd:string ; a owl:Class ; rdfs:comment "The benign fibro-osseous lesions (BFOL) represent a clinically diverse group of disorders of bone that share similar histopathologic features. As a group, they are relatively common in the craniofacial complex, especially the jaws. Common in some inbred strains notably B6C3F1 females. Note that many of the synonyms have been used historically and may not be accurate. See: Albassam MA, Courtney CL (1996) Nonneoplastic and neoplastic lesions of the bone. In: Mohr U, Dungworth DL, Capen CC, Carlton WW, Sundberg JP, Ward JM (eds) Pathobiology of the aging mouse. Vol 2. Musculoskeletal system. ILSI Press, Washington D.C., pp 425-437. AND Albassam MA, Wojcinski ZW, Barsoum NJ, Smith, GS (1991) Spontaneous fibro-osseous proliferative lesions in the sternums and femurs of B6C3F1 mice. Vet Path 28: 381-388."^^xsd:string ; rdfs:label "fibro-osseous lesion"^^xsd:string ; rdfs:subClassOf obo:MPATH_589 . obo:MPATH_591 obo:IAO_0000115 "Accumulation of mature adipose tissue in a healing wound site or otherwise in response to tissue damage."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:591"^^xsd:string ; a owl:Class ; rdfs:label "fatty infiltration"^^xsd:string ; rdfs:subClassOf obo:MPATH_607 . obo:MPATH_592 obo:IAO_0000115 "Excessive formation of dense trabecular bone and mineralized cartilage, especially in long bones, leading to obliteration of marrow spaces and to anemia with myeloid metaplasia and hepatosplenomegaly beginning in infancy, to bone fragility, and to progressive deafness and blindness."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Albers-Schoenberg disease"^^xsd:string, "marble bone disease"^^xsd:string, "marble bones"^^xsd:string ; oboInOwl:id "MPATH:592"^^xsd:string ; a owl:Class ; rdfs:label "osteopetrosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_589 . obo:MPATH_593 obo:IAO_0000115 "Plasma cell myeloma - (ICD-O 9732/3)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:593"^^xsd:string ; a owl:Class ; rdfs:label "myeloma"^^xsd:string ; owl:deprecated true . obo:MPATH_594 obo:IAO_0000115 "Formation of multiple retention cysts from obstruction of ducts or glands by hyperplasia of the lining epithelium."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:594"^^xsd:string ; a owl:Class ; rdfs:label "cystic hyperplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_135 . obo:MPATH_595 obo:IAO_0000115 "The formation of and development of blood cells outside the red pulp of the spleen. Composed of varying numbers of megakaryocytes as well as myeloid and erythroid precursors."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:595"^^xsd:string ; a owl:Class ; rdfs:comment "Production of blood cells in tissues other than the bone marrow. In the mouse, this is usually the liver."^^xsd:string ; rdfs:label "extramedullary hemopoiesis"^^xsd:string ; rdfs:subClassOf obo:MPATH_515 . obo:MPATH_596 obo:IAO_0000115 "The organic response of tissues to external insult, injury or underlying genetic or epigenetic lesion."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:596"^^xsd:string ; a owl:Class ; rdfs:label "pathological process"^^xsd:string ; rdfs:subClassOf obo:MPATH_0 . obo:MPATH_597 obo:IAO_0000115 "Processes occurring during cell and tissue damage of either intrinsic or extrinsic etiology."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:597"^^xsd:string ; a owl:Class ; rdfs:label "cell and tissue damage process"^^xsd:string ; rdfs:subClassOf obo:MPATH_596 . obo:MPATH_598 obo:IAO_0000115 "degenerative entity"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:598"^^xsd:string ; a owl:Class ; rdfs:label "degenerative entity"^^xsd:string ; owl:deprecated true . obo:MPATH_599 obo:IAO_0000115 "developmental process abnormalities"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:599"^^xsd:string ; a owl:Class ; rdfs:label "developmental process abnormalities"^^xsd:string ; rdfs:subClassOf obo:MPATH_596 . obo:MPATH_6 obo:IAO_0000115 "Necrosis characteristic of some inflammatory conditions which represents necrosis with loss of structure of the various cellular and tissue elements; affected tissue manifests a friable, crumbly consistency."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:6"^^xsd:string ; a owl:Class ; rdfs:label "caseous necrosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_4 . obo:MPATH_60 obo:IAO_0000115 "Failure of two cavities, voids or lumens to connect."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:60"^^xsd:string ; a owl:Class ; rdfs:label "communication defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_56 . obo:MPATH_600 obo:IAO_0000115 "Aberrant branch or branching pattern of a branched structure such as the bronchus."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:600"^^xsd:string ; a owl:Class ; rdfs:label "branching defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_56 . obo:MPATH_601 obo:IAO_0000115 "Increase of the size or cellularity of an organ or tissue as a consequence of loss of normal regulation of cell proliferation."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:601"^^xsd:string ; a owl:Class ; rdfs:label "developmental hypertrophy"^^xsd:string ; rdfs:subClassOf obo:MPATH_599 . obo:MPATH_602 obo:IAO_0000115 "An organ or a tissue with an abnormal increase in the number of cells as a consequence of cell proliferation."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:602"^^xsd:string ; a owl:Class ; rdfs:label "hyperplastic tissue"^^xsd:string ; rdfs:subClassOf obo:MPATH_126 . obo:MPATH_603 obo:IAO_0000115 "Anatomically located instance of pathological response or entity."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:603"^^xsd:string ; a owl:Class ; rdfs:label "pathological anatomical entity"^^xsd:string ; rdfs:subClassOf obo:MPATH_0 . obo:MPATH_604 obo:IAO_0000115 "Abnormal increase or decrease in the rate of cell growth or cell division including associated changes in the differentiation state of adult cells."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:604"^^xsd:string ; a owl:Class ; rdfs:comment "Excludes abnormalities of developmental proliferation and differentiation."^^xsd:string ; rdfs:label "defective growth and differentiation process"^^xsd:string ; rdfs:subClassOf obo:MPATH_596 . obo:MPATH_605 obo:IAO_0000115 "A tissue or group of cells in which there has been abnormal transformation of an fully differentiated adult cell or tissue of one kind into a differentiated tissue of another kind."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:605"^^xsd:string ; a owl:Class ; rdfs:comment "Nearly exclusively used in an adult context."^^xsd:string ; rdfs:label "metaplastic tissue"^^xsd:string ; rdfs:subClassOf obo:MPATH_126 . obo:MPATH_606 obo:IAO_0000115 "The pathological process that results in the formation and growth of a neoplasm."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "neoplastic process"^^xsd:string ; oboInOwl:id "MPATH:606"^^xsd:string ; a owl:Class ; rdfs:comment "Literally: new growth of cells. Neoplasia refers to the unscheduled or abnormal growth of cells, potentially resulting in a benign or malignant tumour. Neoplasms include potentially cancerous lesions as well as full malignancies but not all neoplasms are potentially cancerous."^^xsd:string ; rdfs:label "neoplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_596 . obo:MPATH_607 obo:IAO_0000115 "Physical entity or structure associated with normal or abnormal tissue healing or repair following extrinsic or intrinsic damage."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:607"^^xsd:string ; a owl:Class ; rdfs:label "healing and repair structure"^^xsd:string ; rdfs:subClassOf obo:MPATH_603 . obo:MPATH_608 obo:IAO_0000115 "A circumscribed collection of purulent exudate frequently associated with swelling and other signs of inflammation."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:608"^^xsd:string ; a owl:Class ; rdfs:comment "Generally occur following damage or infection with subsequent inflammatory response. Result of the body`s defensive reaction to foreign material."^^xsd:string ; rdfs:label "abscess"^^xsd:string ; rdfs:subClassOf obo:MPATH_607 . obo:MPATH_609 obo:IAO_0000115 "Pus in a body cavity; when used without qualification, refers specifically to pyothorax."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:609"^^xsd:string ; a owl:Class ; rdfs:label "empyema"^^xsd:string ; rdfs:subClassOf obo:MPATH_607 . obo:MPATH_61 obo:IAO_0000115 "Inappropriate curvature of a structure."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:61"^^xsd:string ; a owl:Class ; rdfs:label "curvature defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_56 . obo:MPATH_610 obo:IAO_0000115 "Dilatation of a blood vessel or valve."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:610"^^xsd:string ; a owl:Class ; rdfs:label "angiectasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_474 . obo:MPATH_611 obo:IAO_0000115 "Acute or chronic inflammation of the tongue."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:611"^^xsd:string ; a owl:Class ; rdfs:label "glossitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_612 obo:IAO_0000115 "A circumscribed collection of purulent exudate frequently associated with swelling and other signs of inflammation."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:612"^^xsd:string ; a owl:Class ; rdfs:comment "Alternately a cavity formed by liquefactive necrosis within solid tissue. Obsoleted by MPATH 608"^^xsd:string ; rdfs:label "Abscess"^^xsd:string ; owl:deprecated true . obo:MPATH_613 obo:IAO_0000115 "Coloration, either normal or pathologic, of the skin or tissues resulting from a deposit of pigment."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:613"^^xsd:string ; a owl:Class ; rdfs:label "pigmentation"^^xsd:string ; rdfs:subClassOf obo:MPATH_33 . obo:MPATH_614 obo:IAO_0000115 "Solid material formed by aggregation of discrete units or particles."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:614"^^xsd:string ; a owl:Class ; rdfs:label "concretion"^^xsd:string ; rdfs:subClassOf obo:MPATH_33 . obo:MPATH_615 obo:IAO_0000115 "A disease of the heart muscle or myocardium proper."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:615"^^xsd:string ; a owl:Class ; rdfs:comment "Cardiomyopathies may be classified as either primary or secondary, on the basis of etiology, or on the pathophysiology of the lesion: hypertrophic, dilated, or restrictive."^^xsd:string ; rdfs:label "cardiomyopathy"^^xsd:string ; rdfs:subClassOf obo:MPATH_25 . obo:MPATH_616 obo:IAO_0000115 "Hypertrophy of bone characterised by an abnormal increase in non-neoplastic skeletal bone mass. These may be proliferative or non-proliferative lesions."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "osteosclerosis"^^xsd:string ; oboInOwl:id "MPATH:616"^^xsd:string ; a owl:Class ; rdfs:label "hyperostosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_159 . obo:MPATH_617 obo:IAO_0000115 "Focal lesions of hepatocytes characterised primarily by altered cytoplasmic tinctorial properties. Classified as basophilic, eosinophilic, clear cell or mixed type."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Areas of cellular alteration"^^xsd:string, "Enzyme altered focus"^^xsd:string, "Focus of altered hepatocytes (fah)"^^xsd:string, "Hyperplastic focus"^^xsd:string, "Phenotypically altered focus"^^xsd:string, "Preneoplastic focus"^^xsd:string ; oboInOwl:id "MPATH:617"^^xsd:string ; a owl:Class ; rdfs:comment "More recently amphophilic cell foci, diffusely basophilic cell foci and vacuolated cell foci have been described."^^xsd:string ; rdfs:label "focus of cellular alteration"^^xsd:string ; rdfs:subClassOf obo:MPATH_556 . obo:MPATH_618 obo:IAO_0000115 "Hyperplasia of myeloid lineage, usually in the spleen."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:618"^^xsd:string ; a owl:Class ; rdfs:comment "Myeloid hyperplasia ia a common diagnosis in mouse spleen. In the normal mouse spleen, a low degree of production of myeloid cells occurs (neutrophils, erythroid cells and megakaryocytes). Commonly in aging mice, due to tumors and inflammatory lesions, the mouse myeloid system in bone marrow and spleen react and become hyperplastic. In the spleen it is diagnosed as \"myeloid hyperplasia\" (MH), in the past it was often extramedullary hematopoiesis, which is still used by some but it is normal to a low degree in normal mouse spleen."^^xsd:string ; rdfs:label "myeloid hyperplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_515 . obo:MPATH_619 obo:IAO_0000115 "Septal defect lying between the aorta and pulmonary trunks caused by failure of the spiral septum to separate the truncus arteriosus."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:619"^^xsd:string ; a owl:Class ; rdfs:label "truncoconal septal defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_93 . obo:MPATH_62 obo:IAO_0000115 "Formation of an epithelium bounded cavity not associated with neoplasia."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:62"^^xsd:string ; a owl:Class ; rdfs:label "cyst"^^xsd:string ; rdfs:subClassOf obo:MPATH_56 . obo:MPATH_620 obo:IAO_0000115 "Incomplete closure of the inter-atrial septum due to failure of the primary or secondary septum."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:620"^^xsd:string ; a owl:Class ; rdfs:label "inter-atrial septal defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_93 . obo:MPATH_621 obo:IAO_0000115 "Failure of the inter-ventricular septum to completely close between the left and right ventricles."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:621"^^xsd:string ; a owl:Class ; rdfs:label "inter-ventricular septal defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_93 . obo:MPATH_622 obo:IAO_0000115 "Abnormal retention of lipids within a cell. Physically apparent as lipid within liposomes of parenchymal cells."^^xsd:string ; oboInOwl:hasExactSynonym "lipidosis"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "adipose degeneration"^^xsd:string, "fatty change"^^xsd:string, "fatty degeneration"^^xsd:string ; oboInOwl:id "MPATH:622"^^xsd:string ; a owl:Class ; rdfs:comment "Most commonly associated with degenerative change in the liver."^^xsd:string ; rdfs:label "steatosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_33 . obo:MPATH_623 obo:IAO_0000115 "An adhesion, usually between the iris and the cornea or the lens capsule."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:623"^^xsd:string ; a owl:Class ; rdfs:comment "May also be seen in the uterus ( in humans Asherman`s syndrome)."^^xsd:string ; rdfs:label "synechia"^^xsd:string ; rdfs:subClassOf obo:MPATH_56 . obo:MPATH_624 obo:IAO_0000115 "Turning in of the edges of a structure."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:624"^^xsd:string ; a owl:Class ; rdfs:comment "Not return of an enlarged organ to its normal size."^^xsd:string ; rdfs:label "involution"^^xsd:string ; rdfs:subClassOf obo:MPATH_56 . obo:MPATH_625 obo:IAO_0000115 "Tearing away or separation of two structures or parts."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:625"^^xsd:string ; a owl:Class ; rdfs:label "avulsion"^^xsd:string ; rdfs:subClassOf obo:MPATH_56 . obo:MPATH_626 obo:IAO_0000115 "To sink down, said of an organ or other part. A sinking of an organ or other part, especially its appearance at a natural or artificial orifice."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:626"^^xsd:string ; a owl:Class ; rdfs:label "prolapse"^^xsd:string ; rdfs:subClassOf obo:MPATH_56 . obo:MPATH_627 obo:IAO_0000115 "An inflammatory process in which there is infiltration of polymorphonuclear cells into a more chronic area of inflammation characterized by mononuclear cells, macrophages, lymphocytes and possibly plasma cells."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:627"^^xsd:string ; a owl:Class ; rdfs:label "pyogranulomatous inflammation"^^xsd:string ; rdfs:subClassOf obo:MPATH_215 . obo:MPATH_628 obo:IAO_0000115 "A small rounded mass of inflamed, highly vascular granulation tissue on the skin, frequently having an ulcerated surface. More likely a true neoplasm rather than a reactive lesion."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "lobular capillary hemangioma"^^xsd:string ; oboInOwl:id "MPATH:628"^^xsd:string ; a owl:Class ; rdfs:label "pyogenic granuloma"^^xsd:string ; rdfs:subClassOf obo:MPATH_240 . obo:MPATH_629 obo:IAO_0000115 "Deep cutaneous hemangioma with large dilated vascular spaces that manifests spontaneous involution."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:629"^^xsd:string ; a owl:Class ; rdfs:label "cavernous hemangioma"^^xsd:string ; rdfs:subClassOf obo:MPATH_240 . obo:MPATH_63 obo:IAO_0000115 "The removal of accumulated fluids or solids."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:63"^^xsd:string ; a owl:Class ; rdfs:label "depletion"^^xsd:string ; rdfs:subClassOf obo:MPATH_599 . obo:MPATH_630 obo:IAO_0000115 "Abnormally increased nuclear size."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:630"^^xsd:string ; a owl:Class ; rdfs:label "karyomegaly"^^xsd:string ; rdfs:subClassOf obo:MPATH_460 . obo:MPATH_631 obo:IAO_0000115 "Tissue or cells undergoing hypertrophy, MPATH: 159."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:631"^^xsd:string ; a owl:Class ; rdfs:label "hypertrophic tissue"^^xsd:string ; rdfs:subClassOf obo:MPATH_126 . obo:MPATH_632 obo:IAO_0000115 "Increase in size of hepatocytes characterised by organelle hyperplasia and enlarged cellular volume."^^xsd:string ; oboInOwl:hasDbXref "PMID:7943185"^^xsd:string ; oboInOwl:hasExactSynonym "Hepatocellular hypertrophy."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:632"^^xsd:string ; a owl:Class ; rdfs:comment "Hepatocytomegaly is an enlargement of the hepatocytes and is generally classified into three types: hepatocellular hypertrophy, megalocytosis, and hepatocellular vacuolation. Hepatocellular hypertrophy is an enlargement of cellular diameter without accompanying nuclear changes, leading to a net gain in the dry mass of the liver. Megalocytosis is characterized by enlargement of both the cell and the nucleus, and hepatocellular vacuolation is characterized by vacuolation, or formation of pockets of fluid within the hepatocytes."^^xsd:string ; rdfs:label "hepatocytomegaly"^^xsd:string ; rdfs:subClassOf obo:MPATH_631 . obo:MPATH_633 obo:IAO_0000115 "Presence of concretions in the gallbladder or bile ducts."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:633"^^xsd:string ; a owl:Class ; rdfs:label "cholelithiasis"^^xsd:string ; rdfs:subClassOf obo:MPATH_614 . obo:MPATH_634 obo:IAO_0000115 "Focal suppurative inflammation of the skin and subcutaneous tissues, enclosing a central slough or `core`."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Boil"^^xsd:string ; oboInOwl:id "MPATH:634"^^xsd:string ; a owl:Class ; rdfs:label "furunculosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_635 obo:IAO_0000115 "Swelling of the kidneys when urine flow is obstructed in any of part of the urinary tract. Severe form of pyelectasia."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:635"^^xsd:string ; a owl:Class ; rdfs:label "hydronephrosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_708 . obo:MPATH_636 obo:IAO_0000115 "Inflammation of fatty tissue."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:636"^^xsd:string ; a owl:Class ; rdfs:label "steatitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_637 obo:IAO_0000115 "A retention cyst, resulting from an obstruction to the duct of a gland, within a bursa."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:637"^^xsd:string ; a owl:Class ; rdfs:label "bursal cyst"^^xsd:string ; rdfs:subClassOf obo:MPATH_62 . obo:MPATH_638 obo:IAO_0000115 "An acute, diffuse, spreading, edematous, suppurative inflammation of the deep subcutaneous tissues and sometimes muscle, which may be associated with abscess formation."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:638"^^xsd:string ; a owl:Class ; rdfs:comment "It is usually caused by infection of an operative or traumatic wound, burn or other cutaneous lesion by various bacteria, but group A streptococci and Staphylococcus aureus are the most common aetiological agents."^^xsd:string ; rdfs:label "cellulitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_639 obo:IAO_0000115 "Accumulation of water in the ventricles of the brain."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:639"^^xsd:string ; a owl:Class ; rdfs:label "hydrocephalus"^^xsd:string ; rdfs:subClassOf obo:MPATH_33 . obo:MPATH_64 obo:IAO_0000115 "Abnormal development (of organs or tissues) or an abnormal structure resulting from such growth."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:64"^^xsd:string ; a owl:Class ; rdfs:comment "The word dysplasia as commonly used refers to a precursor state to neoplasia. This is not the context used for this MPATH term."^^xsd:string ; rdfs:label "developmental dysplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_599 . obo:MPATH_640 obo:IAO_0000115 "Deposition of organic bone matrix."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:640"^^xsd:string ; a owl:Class ; rdfs:label "osteoid deposition"^^xsd:string ; rdfs:subClassOf obo:MPATH_178 . obo:MPATH_641 obo:IAO_0000115 "Intradermal or subcutaneous cyst, the wall of which is stratified epithelium containing keratohyalin granules, surrounding a core of debris."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:641"^^xsd:string ; a owl:Class ; rdfs:label "epidermal inclusion cyst"^^xsd:string ; rdfs:subClassOf obo:MPATH_62 . obo:MPATH_642 obo:IAO_0000115 "Intra or extracellular deposition of cholesterol."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:642"^^xsd:string ; a owl:Class ; rdfs:comment "Often diagnosed morphologically by the presence of cholesterol clefts - bare regions of a section where accumulated cholesterol has been removed by histological processing."^^xsd:string ; rdfs:label "cholesterol deposition"^^xsd:string ; rdfs:subClassOf obo:MPATH_33 . obo:MPATH_643 obo:IAO_0000115 "Non-cellular fluid that filters from the circulatory system and accumulates in lesions or areas of inflammation."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:643"^^xsd:string ; a owl:Class ; rdfs:label "serous exudate"^^xsd:string ; rdfs:subClassOf obo:MPATH_106 . obo:MPATH_644 obo:IAO_0000115 "Accumulation of chitinase-like protein."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:644"^^xsd:string ; a owl:Class ; rdfs:label "crystalloid formation"^^xsd:string ; rdfs:subClassOf obo:MPATH_33 . obo:MPATH_645 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-03-22T03:09:08Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:645"^^xsd:string ; a owl:Class ; rdfs:label "epicarditis"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_646 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-03-22T03:12:07Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:646"^^xsd:string ; a owl:Class ; rdfs:label "chondroarthritis"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_647 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-03-22T03:14:35Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:647"^^xsd:string ; a owl:Class ; rdfs:label "interstitial nephritis"^^xsd:string ; rdfs:subClassOf obo:MPATH_212, obo:MPATH_676 . obo:MPATH_648 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-03-22T03:16:02Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:648"^^xsd:string ; a owl:Class ; rdfs:label "interstitial pancreatitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_649 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-03-22T03:16:36Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:649"^^xsd:string ; a owl:Class ; rdfs:label "otitis media"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_65 obo:IAO_0000115 "Underdevelopment of an organ due to a decrease in the number of cells through failure to proliferate leading to lack of development."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:65"^^xsd:string ; a owl:Class ; rdfs:label "developmental hypoplasia"^^xsd:string ; owl:deprecated true . obo:MPATH_650 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-03-22T03:17:25Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:650"^^xsd:string ; a owl:Class ; rdfs:label "proliferative dermatitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_651 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-03-22T03:18:00Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:651"^^xsd:string ; a owl:Class ; rdfs:label "ventral glossitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_611 . obo:MPATH_652 obo:IAO_0000115 "Benign proliferation of histiocytes."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-03-22T03:19:47Z"^^xsd:string ; oboInOwl:hasAlternativeId "MPATH:146"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:652"^^xsd:string ; a owl:Class ; rdfs:label "histiocytosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_194, obo:MPATH_602 . obo:MPATH_653 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-03-22T03:20:12Z"^^xsd:string ; oboInOwl:hasExactSynonym "histiocytosis X"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:653"^^xsd:string ; a owl:Class ; rdfs:label "langerhans cell histiocytosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_652 . obo:MPATH_654 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-03-22T03:20:52Z"^^xsd:string ; oboInOwl:hasExactSynonym "hemophagocytic syndrome"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:654"^^xsd:string ; a owl:Class ; rdfs:label "non-Langerhans cell histiocytosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_652 . obo:MPATH_655 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-03-22T03:36:05Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:655"^^xsd:string ; a owl:Class ; rdfs:label "lingual adenitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_656 obo:IAO_0000115 "Rupture or disruption of erythrocytes with release of contents."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-04-01T12:08:29Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:656"^^xsd:string ; a owl:Class ; rdfs:comment "May be immune-mediated, induced by infectious organisms, or intrinsic disturbance of cell physiology or membrane/cytoskeletal integrity."^^xsd:string ; rdfs:label "hemolysis"^^xsd:string ; rdfs:subClassOf obo:MPATH_25 . obo:MPATH_657 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-03-22T03:45:17Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:657"^^xsd:string ; a owl:Class ; rdfs:label "rhinitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_658 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-03-22T03:45:36Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:658"^^xsd:string ; a owl:Class ; rdfs:label "foreign body rhinitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_657 . obo:MPATH_659 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-03-22T03:46:02Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:659"^^xsd:string ; a owl:Class ; rdfs:label "foreign body dermatitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_196 . obo:MPATH_66 obo:IAO_0000115 "Increase in the diameter of an orifice or tubular structure beyond its normal dimensions."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:66"^^xsd:string ; a owl:Class ; rdfs:label "dilatation"^^xsd:string ; rdfs:subClassOf obo:MPATH_56 . obo:MPATH_660 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-03-22T03:46:42Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:660"^^xsd:string ; a owl:Class ; rdfs:label "gastritis"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_661 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-03-22T03:47:05Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:661"^^xsd:string ; a owl:Class ; rdfs:label "foreign body gastritis"^^xsd:string ; rdfs:subClassOf obo:MPATH_660 . obo:MPATH_662 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-03-22T03:47:40Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:662"^^xsd:string ; a owl:Class ; rdfs:label "foreign body glossitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_611 . obo:MPATH_663 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-03-22T03:48:33Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:663"^^xsd:string ; a owl:Class ; rdfs:label "peritonitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_664 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-03-22T03:48:51Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:664"^^xsd:string ; a owl:Class ; rdfs:label "granulomatous peritonitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_215, obo:MPATH_663 . obo:MPATH_665 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-03-22T03:49:26Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:665"^^xsd:string ; a owl:Class ; rdfs:label "foreign body granulomatous peritonitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_215, obo:MPATH_663 . obo:MPATH_666 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-03-22T03:50:05Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:666"^^xsd:string ; a owl:Class ; rdfs:label "periodontitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_667 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-03-22T03:50:24Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:667"^^xsd:string ; a owl:Class ; rdfs:label "foreign body periodontitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_666 . obo:MPATH_668 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-03-22T03:51:20Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:668"^^xsd:string ; a owl:Class ; rdfs:label "tracheitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_669 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-03-22T03:52:00Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:669"^^xsd:string ; a owl:Class ; rdfs:label "foreign body tracheitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_668 . obo:MPATH_67 obo:IAO_0000115 "Abnormal location, orientation, number, loss or non-specified deformity of a structure or tissue."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:67"^^xsd:string ; a owl:Class ; rdfs:label "displacement and deformity"^^xsd:string ; rdfs:subClassOf obo:MPATH_56 . obo:MPATH_670 obo:IAO_0000115 "A mixed inflammatory cell infiltrate, primarily macrophages and some syncitial cells, around the heart attached to the epicardium."^^xsd:string ; oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-03-22T03:52:48Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:670"^^xsd:string ; a owl:Class ; rdfs:label "granulomatous epicarditis"^^xsd:string ; rdfs:subClassOf obo:MPATH_215, obo:MPATH_645 . obo:MPATH_671 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-19T04:01:58Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:671"^^xsd:string ; a owl:Class ; rdfs:label "mastitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_672 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-19T04:05:08Z"^^xsd:string ; oboInOwl:hasExactSynonym "Urticaria pigmentosa"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:672"^^xsd:string ; a owl:Class ; rdfs:label "mastocytosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_673 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-19T04:06:30Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:673"^^xsd:string ; a owl:Class ; rdfs:label "metritis"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_674 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-19T04:08:00Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:674"^^xsd:string ; a owl:Class ; rdfs:label "osteomyelitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_675 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-19T04:09:12Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:675"^^xsd:string ; a owl:Class ; rdfs:label "psoriasiform dermatitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_196 . obo:MPATH_676 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-19T04:10:14Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:676"^^xsd:string ; a owl:Class ; rdfs:label "nephritis"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_677 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-19T04:10:51Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:677"^^xsd:string ; a owl:Class ; rdfs:label "pyelonephritis"^^xsd:string ; rdfs:subClassOf obo:MPATH_676 . obo:MPATH_678 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-19T04:12:09Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:678"^^xsd:string ; a owl:Class ; rdfs:label "septic nephritis"^^xsd:string ; rdfs:subClassOf obo:MPATH_676 . obo:MPATH_679 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-19T04:12:43Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:679"^^xsd:string ; a owl:Class ; rdfs:label "urocystitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_68 obo:IAO_0000115 "A blind ended outpouching through the wall of a tubular organ or bounded cavity."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:68"^^xsd:string ; a owl:Class ; rdfs:label "diverticulum"^^xsd:string ; rdfs:subClassOf obo:MPATH_56 . obo:MPATH_680 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-19T04:13:07Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:680"^^xsd:string ; a owl:Class ; rdfs:label "septic urocystitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_679 . obo:MPATH_681 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-19T04:13:38Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:681"^^xsd:string ; a owl:Class ; rdfs:label "septicemia"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_682 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-19T04:15:16Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:682"^^xsd:string ; a owl:Class ; rdfs:label "arteritis"^^xsd:string ; rdfs:subClassOf obo:MPATH_201 . obo:MPATH_683 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-19T04:16:05Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:683"^^xsd:string ; a owl:Class ; rdfs:label "degenerative arthritis"^^xsd:string ; rdfs:subClassOf obo:MPATH_195, obo:MPATH_25, obo:MPATH_684 . obo:MPATH_684 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-19T04:17:26Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:684"^^xsd:string ; a owl:Class ; rdfs:label "arthropathy"^^xsd:string ; rdfs:subClassOf obo:MPATH_25, obo:MPATH_655 . obo:MPATH_685 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-19T04:26:34Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:685"^^xsd:string ; a owl:Class ; rdfs:label "accessory organ"^^xsd:string ; rdfs:subClassOf obo:MPATH_84 . obo:MPATH_686 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-19T04:30:20Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:686"^^xsd:string ; a owl:Class ; rdfs:label "amputation"^^xsd:string ; rdfs:subClassOf obo:MPATH_67 . obo:MPATH_687 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-19T04:30:41Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:687"^^xsd:string ; a owl:Class ; rdfs:label "autoamputation"^^xsd:string ; rdfs:subClassOf obo:MPATH_686 . obo:MPATH_688 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-19T04:34:31Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:688"^^xsd:string ; a owl:Class ; rdfs:label "aortitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_201 . obo:MPATH_689 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-19T04:35:13Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:689"^^xsd:string ; a owl:Class ; rdfs:label "lymphangitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_201 . obo:MPATH_69 obo:IAO_0000115 "ectopia"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:69"^^xsd:string ; a owl:Class ; rdfs:comment "obsolete - Subsumed into heterotopia MPATH:76"^^xsd:string ; rdfs:label "ectopia"^^xsd:string ; owl:deprecated true . obo:MPATH_690 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-19T04:36:16Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:690"^^xsd:string ; a owl:Class ; rdfs:label "phlebitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_201 . obo:MPATH_691 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-19T04:45:08Z"^^xsd:string ; oboInOwl:hasExactSynonym "cutaneous abscess"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:691"^^xsd:string ; a owl:Class ; rdfs:label "pustule"^^xsd:string ; rdfs:subClassOf obo:MPATH_608 . obo:MPATH_692 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-19T04:56:39Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:692"^^xsd:string ; a owl:Class ; rdfs:label "ulcerative blepharitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_546 . obo:MPATH_693 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-19T05:02:23Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:693"^^xsd:string ; a owl:Class ; rdfs:label "pyometra"^^xsd:string ; rdfs:subClassOf obo:MPATH_673 . obo:MPATH_694 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-19T05:05:05Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:694"^^xsd:string ; a owl:Class ; rdfs:label "acidophilic anterior pituitary gland adenoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_270 . obo:MPATH_695 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-19T05:12:17Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:695"^^xsd:string ; a owl:Class ; rdfs:label "spindle cell sarcoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_551 . obo:MPATH_696 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-19T05:13:13Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:696"^^xsd:string ; a owl:Class ; rdfs:label "spindle cell hyperplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_602 . obo:MPATH_697 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-19T05:17:30Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:697"^^xsd:string ; a owl:Class ; rdfs:label "alopecia areata"^^xsd:string ; rdfs:subClassOf obo:MPATH_26 . obo:MPATH_698 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-19T05:23:34Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "osteophytes"^^xsd:string ; oboInOwl:id "MPATH:698"^^xsd:string ; a owl:Class ; rdfs:label "exostosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_126 . obo:MPATH_699 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-19T05:24:05Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:699"^^xsd:string ; a owl:Class ; rdfs:label "ankylosing exostosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_698 . obo:MPATH_7 obo:IAO_0000115 "A type of necrosis in which the affected cells or tissue are reduced to homogeneous eosinophilic mass without nuclear staining, as a result of the protein coagulation, eg. Infarct. Tissue architecture persists."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:7"^^xsd:string ; a owl:Class ; rdfs:label "coagulation necrosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_4 . obo:MPATH_70 obo:IAO_0000115 "An abnormal passage between two internal organs or leading from a cavity to the body surface."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:70"^^xsd:string ; a owl:Class ; rdfs:label "fistula"^^xsd:string ; rdfs:subClassOf obo:MPATH_56 . obo:MPATH_700 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-19T05:24:55Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:700"^^xsd:string ; a owl:Class ; rdfs:label "ascites"^^xsd:string ; rdfs:subClassOf obo:MPATH_33 . obo:MPATH_701 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-19T05:29:50Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:701"^^xsd:string ; a owl:Class ; rdfs:label "developmental aspermia"^^xsd:string ; rdfs:subClassOf obo:MPATH_599, obo:MPATH_796 . obo:MPATH_702 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-19T05:30:40Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:702"^^xsd:string ; a owl:Class ; rdfs:label "acquired aspermia"^^xsd:string ; rdfs:subClassOf obo:MPATH_796 . obo:MPATH_703 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-19T05:31:21Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:703"^^xsd:string ; a owl:Class ; rdfs:label "developmental hypoplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_599 . obo:MPATH_704 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-19T08:28:41Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:704"^^xsd:string ; a owl:Class ; rdfs:label "thyroiditis"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_705 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-19T10:33:51Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:705"^^xsd:string ; a owl:Class ; rdfs:label "acinar atrophy"^^xsd:string ; rdfs:subClassOf obo:MPATH_127 . obo:MPATH_706 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-19T10:37:34Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:706"^^xsd:string ; a owl:Class ; rdfs:label "cryptorchidism"^^xsd:string ; rdfs:subClassOf obo:MPATH_86 . obo:MPATH_707 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-20T08:44:41Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:707"^^xsd:string ; a owl:Class ; rdfs:label "angiolipoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_415 . obo:MPATH_708 obo:IAO_0000115 "Distension of the renal pelvis by accumulated fluid or urine."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-06-06T03:01:54Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:708"^^xsd:string ; a owl:Class ; rdfs:comment "May be fetal or adult."^^xsd:string ; rdfs:label "pyelectasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_33 . obo:MPATH_709 obo:IAO_0000115 "Malignant tumor of striated muscle or pluripotential mesenchymal stem cells composed mainly of small round cells, with some partial skeletal muscle differentiation."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-06-06T03:24:13Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:709"^^xsd:string ; a owl:Class ; rdfs:label "alveolar rhabdomyosarcoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_428 . obo:MPATH_71 obo:IAO_0000115 "Failure of two or more structures ( not voids or lumens) to join together."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:71"^^xsd:string ; a owl:Class ; rdfs:label "fusion process defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_599 . obo:MPATH_710 obo:IAO_0000115 "Malignant mesenchymal tumor that morphologically and phenotypically resembles embryonal skeletal muscle."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-06-06T03:31:11Z"^^xsd:string ; oboInOwl:hasExactSynonym "Myosarcoma "^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym " Rhabdopoietic Sarcoma"^^xsd:string, " Sarcoma Botryoides [Soft Tissues]"^^xsd:string, "Embryonal Sarcoma"^^xsd:string, "Malignant Rhabdomyoma"^^xsd:string ; oboInOwl:id "MPATH:710"^^xsd:string ; a owl:Class ; rdfs:comment "Includes spindle cell, botryoid, anaplastic."^^xsd:string ; rdfs:label "embryonal rhabdomyosarcoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_428 . obo:MPATH_711 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-20T12:06:02Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:711"^^xsd:string ; a owl:Class ; rdfs:label "situs ambiguus"^^xsd:string ; rdfs:subClassOf obo:MPATH_470 . obo:MPATH_712 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-20T12:06:38Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:712"^^xsd:string ; a owl:Class ; rdfs:label "heterotaxy"^^xsd:string ; rdfs:subClassOf obo:MPATH_470 . obo:MPATH_713 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-20T12:07:15Z"^^xsd:string ; oboInOwl:hasDbXref "XX:"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "situs inversus with dextrocardia"^^xsd:string ; oboInOwl:id "MPATH:713"^^xsd:string ; a owl:Class ; rdfs:label "situs ambiguus totalis"^^xsd:string ; rdfs:subClassOf obo:MPATH_720 . obo:MPATH_714 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-20T12:08:14Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:714"^^xsd:string ; a owl:Class ; rdfs:label "situs inversus with levocardia"^^xsd:string ; rdfs:subClassOf obo:MPATH_720 . obo:MPATH_715 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-20T12:10:00Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:715"^^xsd:string ; a owl:Class ; rdfs:label "sinusitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_716 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-20T12:14:20Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "primary ciliary dyskinesis"^^xsd:string ; oboInOwl:id "MPATH:716"^^xsd:string ; a owl:Class ; rdfs:label "ciliary motility defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_17 . obo:MPATH_717 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-20T02:28:51Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:717"^^xsd:string ; a owl:Class ; rdfs:comment "Most often used in the context of bone."^^xsd:string ; rdfs:label "sequestrum"^^xsd:string ; rdfs:subClassOf obo:MPATH_1 . obo:MPATH_718 obo:IAO_0000115 "Generally benign germ cell derived tumors of male or female containing derivatives from all three germ layers with differentiation in the malignant form being poor. Pre-sacral tumors located in the retrorectal space between the rectum and the sacrococcygeal part of the spine."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-06-06T03:39:01Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:718"^^xsd:string ; a owl:Class ; rdfs:label "pre-sacral teratoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_322 . obo:MPATH_719 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-20T12:04:36Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:719"^^xsd:string ; a owl:Class ; rdfs:label "bronchiectasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_474 . obo:MPATH_72 obo:IAO_0000115 "Increase in the rate of growth of an organism, organ or tissue as a consequence of increased proliferation, reduced cell death, or a combination. Not due to an increase in cell size; see Hypertrophy MPATH: 159."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:72"^^xsd:string ; a owl:Class ; rdfs:label "growth acceleration"^^xsd:string ; rdfs:subClassOf obo:MPATH_599 . obo:MPATH_720 oboInOwl:created_by "George Gkoutos"^^xsd:string ; oboInOwl:creation_date "2011-02-20T12:05:38Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:720"^^xsd:string ; a owl:Class ; rdfs:label "situs inversus"^^xsd:string ; rdfs:subClassOf obo:MPATH_470 . obo:MPATH_721 obo:IAO_0000115 "Generally benign germ cell derived tumors of male or female containing derivatives from all three germ layers with differentiation in the malignant form being poor. Sacrococcygeal tumors are located at the base of the coccyx."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-06-06T03:51:12Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:721"^^xsd:string ; a owl:Class ; rdfs:label "sacrococcygeal teratoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_322 . obo:MPATH_722 obo:IAO_0000115 "Benign stromal tumors of the soft tissue with skeletal muscle differentiation."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-06-06T03:59:49Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:722"^^xsd:string ; a owl:Class ; rdfs:comment "Adult and fetal types."^^xsd:string ; rdfs:label "rhabdomyoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_423 . obo:MPATH_723 obo:IAO_0000115 "Systemic manifestation of MPATH: 407."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-06-06T04:11:04Z"^^xsd:string ; oboInOwl:hasExactSynonym "Desmoid Tumor"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym " Musculoaponeurotic Fibromatosis"^^xsd:string, "Aggressive Fibromatosis"^^xsd:string, "Plantar Fibromatosis (Ledderhose Disease)"^^xsd:string ; oboInOwl:id "MPATH:723"^^xsd:string ; a owl:Class ; rdfs:label "fibromatosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_407 . obo:MPATH_724 obo:IAO_0000115 "Dermal, subcutaneous, or tendinous lesions characterized by accumulations of lipid-laden macrophages often rich in cholesterol."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-06-08T03:43:07Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:724"^^xsd:string ; a owl:Class ; rdfs:label "xanthoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_42 . obo:MPATH_725 oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-10-26T02:02:02Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:725"^^xsd:string ; a owl:Class ; rdfs:label "chronic interstitial nephritis"^^xsd:string ; rdfs:subClassOf obo:MPATH_647 . obo:MPATH_726 oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-10-26T02:05:04Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:726"^^xsd:string ; a owl:Class ; rdfs:label "hemosiderosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_41 . obo:MPATH_727 oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-10-26T02:05:29Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:727"^^xsd:string ; a owl:Class ; rdfs:label "hepatic hemosiderosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_726 . obo:MPATH_728 oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-10-26T02:06:12Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:728"^^xsd:string ; a owl:Class ; rdfs:label "pulmonary hemosiderosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_726 . obo:MPATH_729 oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-10-26T02:06:46Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:729"^^xsd:string ; a owl:Class ; rdfs:label "splenic melanosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_44 . obo:MPATH_73 obo:IAO_0000115 "The cessation of fetal or embryonic growth beyond a particular stage."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:73"^^xsd:string ; a owl:Class ; rdfs:label "growth arrest"^^xsd:string ; rdfs:subClassOf obo:MPATH_599 . obo:MPATH_730 oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-10-26T02:13:35Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:730"^^xsd:string ; a owl:Class ; rdfs:label "renal tubular concretion"^^xsd:string ; rdfs:subClassOf obo:MPATH_614 . obo:MPATH_731 oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-10-26T02:17:02Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:731"^^xsd:string ; a owl:Class ; rdfs:label "Leydig cell hyperplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_602 . obo:MPATH_732 oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-10-26T02:19:12Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:732"^^xsd:string ; a owl:Class ; rdfs:label "tracheal gland ectasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_474 . obo:MPATH_733 obo:IAO_0000115 "A uterus distended with a fluid containing large quantities of mucin."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-10-26T02:22:56Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:733"^^xsd:string ; a owl:Class ; rdfs:label "mucometra"^^xsd:string ; rdfs:subClassOf obo:MPATH_547 . obo:MPATH_734 oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-10-26T02:23:54Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:734"^^xsd:string ; a owl:Class ; rdfs:label "acute blepharitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_546 . obo:MPATH_735 obo:IAO_0000115 "Thickening of the cementum layer of the molars."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-10-26T02:25:55Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:735"^^xsd:string ; a owl:Class ; rdfs:comment "This is usually a normal adaptive response, serving to improve the functional properties of teeth during aging."^^xsd:string ; rdfs:label "molar hypercementosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_33 . obo:MPATH_736 oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-10-26T02:29:29Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:736"^^xsd:string ; a owl:Class ; rdfs:comment "A variety of cysts develop in the ovary. They are subdivided based on where they develop anatomically. Ovarian follicles in this case become large and fluid filled."^^xsd:string ; rdfs:label "ovarian follicular cyst"^^xsd:string ; rdfs:subClassOf obo:MPATH_62 . obo:MPATH_737 oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-10-26T02:33:06Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:737"^^xsd:string ; a owl:Class ; rdfs:comment "Usually rd6-outer retinal photoreceptor degeneration"^^xsd:string ; rdfs:label "retinal degeneration"^^xsd:string ; rdfs:subClassOf obo:MPATH_25 . obo:MPATH_738 oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-10-26T02:34:35Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:738"^^xsd:string ; a owl:Class ; rdfs:comment "The uterus of older female mice often becomes distended with numerous fluid filled cysts that extend from the endometrium."^^xsd:string ; rdfs:label "uterine cystic endometrial hyperplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_134 . obo:MPATH_739 obo:IAO_0000115 "Extravascular blood between retina and choroid"^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-10-26T02:36:03Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:739"^^xsd:string ; a owl:Class ; rdfs:label "sub-retinal hemorrhage"^^xsd:string ; rdfs:subClassOf obo:MPATH_119 . obo:MPATH_74 obo:IAO_0000115 "A focal malformation resembling a neoplasm which results from faulty development of an organ; composed of an abnormal mixture of tissue elements, or an abnormal proportion of a single element. Growth and location are usually normal for that tissue cf. Heterotopia/Choristoma MPATH:76/MPATH:477."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:74"^^xsd:string ; a owl:Class ; rdfs:label "hamartoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_56 . obo:MPATH_740 obo:IAO_0000115 "Tiny yellow or white deposits of lamellar or amorphous extracellular material that build up between retina and retinal pigment epithelium."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-10-26T02:38:14Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:740"^^xsd:string ; a owl:Class ; rdfs:label "drusen"^^xsd:string ; rdfs:subClassOf obo:MPATH_45 . obo:MPATH_741 obo:IAO_0000115 "An increase in size of the spleen."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-10-26T02:56:13Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:741"^^xsd:string ; a owl:Class ; rdfs:label "splenomegaly"^^xsd:string ; rdfs:subClassOf obo:MPATH_56 . obo:MPATH_742 obo:IAO_0000115 "Rupture of the intervertebral disc, usually dorsally to compress the spinal cord, secondary to trauma."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-10-26T02:59:08Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:742"^^xsd:string ; a owl:Class ; rdfs:comment "These become more common with age."^^xsd:string ; rdfs:label "intervertebral disk prolapse"^^xsd:string ; rdfs:subClassOf obo:MPATH_626 . obo:MPATH_743 obo:IAO_0000115 "Accumulation of clear large vacuoles in hepatocytes (most likely lipid pending frozen sections and oil red O or other lipid stains) around central veins."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-10-26T03:04:08Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:743"^^xsd:string ; a owl:Class ; rdfs:label "hepatic centrolobular fatty metamorphosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_622 . obo:MPATH_744 obo:IAO_0000115 "Release of melanin pigment in the dermis."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-10-26T03:06:29Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:744"^^xsd:string ; a owl:Class ; rdfs:comment "Observed as melanin pigment within macrophages in the dermis. Inflammation in the epidermis stimulates melanocytes to increase the synthesis of melanin and subsequently to transfer the pigment to surrounding keratinocytes. If the basal layer is injured (e.g. lichen planus), melanin pigment is released and subsequently trapped by macrophages in the papillary dermis."^^xsd:string ; rdfs:label "pigmentary incontinence"^^xsd:string ; rdfs:subClassOf obo:MPATH_47 . obo:MPATH_745 obo:IAO_0000115 "Degenerative changes in skeletal muscle including hyalinization, swelling, fragmentation, vacuolation eventually resulting in death of muscle fibers."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-10-26T03:15:56Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:745"^^xsd:string ; a owl:Class ; rdfs:label "zenker's necrosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_4 . obo:MPATH_746 obo:IAO_0000115 "Fragmentation and erosion of articular cartilage."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-10-26T03:18:38Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:746"^^xsd:string ; a owl:Class ; rdfs:label "cartilagenous erosion"^^xsd:string ; rdfs:subClassOf obo:MPATH_25 . obo:MPATH_747 obo:IAO_0000115 "Pink amorphous material (amyloid) deposited within the renal tubules."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-10-26T03:34:30Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:747"^^xsd:string ; a owl:Class ; rdfs:label "renal tubular amyloidosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_34 . obo:MPATH_748 obo:IAO_0000115 "An old organized thrombus that has been recanalized to permit blood flow."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-10-26T03:36:06Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:748"^^xsd:string ; a owl:Class ; rdfs:label "recanalised thrombus"^^xsd:string ; rdfs:subClassOf obo:MPATH_125 . obo:MPATH_749 obo:IAO_0000115 "Various degrees of pulmonary interstitial fibrosis."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-10-26T03:37:48Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:749"^^xsd:string ; a owl:Class ; rdfs:label "focal pulmonary fibrosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_181 . obo:MPATH_75 obo:IAO_0000115 "Protrusion of a loop or wall of an organ through an abnormal opening."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:75"^^xsd:string ; a owl:Class ; rdfs:label "hernia"^^xsd:string ; rdfs:subClassOf obo:MPATH_56 . obo:MPATH_750 obo:IAO_0000115 "Neoplastic proliferation of cuboidal cells lining alveoli most likely type II pneumocytes."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-10-26T03:40:09Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:750"^^xsd:string ; a owl:Class ; rdfs:label "pulmonary adenomatosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_270 . obo:MPATH_751 obo:IAO_0000115 "Free pigment in anterior chamber/elsewhere in eye."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-10-26T03:41:56Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:751"^^xsd:string ; a owl:Class ; rdfs:label "pigment dispersion"^^xsd:string ; rdfs:subClassOf obo:MPATH_47 . obo:MPATH_752 obo:IAO_0000115 "loss of hair resulting from a behavioral abnormality in which the mouse, or more often other mice mice in the same box, remove hairs, initially vibrissae, from each other."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-10-26T03:44:05Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:752"^^xsd:string ; a owl:Class ; rdfs:comment "This is a form of trichotillomania."^^xsd:string ; rdfs:label "barbered"^^xsd:string ; rdfs:subClassOf obo:MPATH_56 . obo:MPATH_753 obo:IAO_0000115 "The forestomach of the mouse is lined by stratified squamous epithelia. At the limiting ridge there is hyperplasia to various degrees in which this epithelium proliferates to form raised areas on thin fibrovascular stalks."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-10-26T03:47:01Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:753"^^xsd:string ; a owl:Class ; rdfs:label "gastric forestomach papillomatous hyperplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_138 . obo:MPATH_754 obo:IAO_0000115 "Spleen contains foci of macrophages containing yellow brown pigment that is positive for iron using Prussian blue."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T03:30:56Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:754"^^xsd:string ; a owl:Class ; rdfs:label "splenic hemosiderosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_726 . obo:MPATH_755 obo:IAO_0000115 "Small foci of mineralization within the interstitium between alveoli."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T03:33:11Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:755"^^xsd:string ; a owl:Class ; rdfs:label "pulmonary interstitial mineralisation"^^xsd:string ; rdfs:subClassOf obo:MPATH_555, obo:MPATH_757 . obo:MPATH_756 obo:IAO_0000115 "Chronic inflammation in and around small and medium sized arteries, often in more than one location."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T03:41:52Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Kussmaul disease"^^xsd:string, "Kussmaul-Maier disease"^^xsd:string ; oboInOwl:id "MPATH:756"^^xsd:string ; a owl:Class ; rdfs:label "polyarteritis nodosa"^^xsd:string ; rdfs:subClassOf obo:MPATH_682 . obo:MPATH_757 obo:IAO_0000115 "Foci of mineralization within the interstitium of a tissue."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T03:54:07Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:757"^^xsd:string ; a owl:Class ; rdfs:label "interstitial mineralization"^^xsd:string ; rdfs:subClassOf obo:MPATH_555 . obo:MPATH_758 obo:IAO_0000115 "Small foci of mineralization within the interstitium between tubules."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T03:57:16Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:758"^^xsd:string ; a owl:Class ; rdfs:label "renal interstitial mineralisation"^^xsd:string ; rdfs:subClassOf obo:MPATH_757 . obo:MPATH_759 obo:IAO_0000115 "Appearance of clinical and/or subclinical signs and symptoms associated with pregnancy when the animal is not pregnant"^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T04:02:14Z"^^xsd:string ; oboInOwl:hasDbXref "XX:"^^xsd:string ; oboInOwl:hasExactSynonym "false pregnancy"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:759"^^xsd:string ; a owl:Class ; rdfs:comment "Virgin females have mammary acini and ducts dilated to various degrees filled with proteinaceous materials suggestive of lactation or involution."^^xsd:string ; rdfs:label "pseudocyesis"^^xsd:string ; rdfs:subClassOf obo:MPATH_474 . obo:MPATH_76 obo:IAO_0000115 "Congenital appearance of a body part or tissue or cell type in a region where it is not normally found ( topographical anomaly)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Ectopia"^^xsd:string ; oboInOwl:id "MPATH:76"^^xsd:string ; a owl:Class ; rdfs:label "heterotopia"^^xsd:string ; rdfs:subClassOf obo:MPATH_67 . obo:MPATH_760 obo:IAO_0000115 "Marked dilatation of the ovarian bursa."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T04:07:28Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:760"^^xsd:string ; a owl:Class ; rdfs:comment "May compress the ovary"^^xsd:string ; rdfs:label "ovarian bursal cyst"^^xsd:string ; rdfs:subClassOf obo:MPATH_637 . obo:MPATH_761 obo:IAO_0000115 "Linear palisaiding of nuclei within thin pale muscle fibers suggestive of repair."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T04:14:39Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:761"^^xsd:string ; a owl:Class ; rdfs:label "muscle regeneration"^^xsd:string ; rdfs:subClassOf obo:MPATH_607 . obo:MPATH_762 obo:IAO_0000115 "Thyroid gland follicles are filled with colloid but vary greatly in size."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T04:18:38Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:762"^^xsd:string ; a owl:Class ; rdfs:comment "Suggestive of goiter or other functional abnormality."^^xsd:string ; rdfs:label "thyroid follicle pleomorphism"^^xsd:string ; rdfs:subClassOf obo:MPATH_33 . obo:MPATH_763 obo:IAO_0000115 "Salivary gland duct occlusion resulting in massive enlargement forming a large cyst-like structure."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T04:23:20Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:763"^^xsd:string ; a owl:Class ; rdfs:label "sialocele"^^xsd:string ; rdfs:subClassOf obo:MPATH_62 . obo:MPATH_764 obo:IAO_0000115 "A fracture is the (local) separation of a bone into two, or more, pieces under the action of stress."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T04:29:57Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:764"^^xsd:string ; a owl:Class ; rdfs:label "fracture"^^xsd:string ; rdfs:subClassOf obo:MPATH_56 . obo:MPATH_765 obo:IAO_0000115 "Break in bone associated with exostoses."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T04:34:27Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:765"^^xsd:string ; a owl:Class ; rdfs:label "fracture and healing"^^xsd:string ; rdfs:subClassOf obo:MPATH_764 . obo:MPATH_766 obo:IAO_0000115 "The lamina propria is distended with amorphous hyalinized material interpreted to be amyloid protein."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T06:59:37Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:766"^^xsd:string ; a owl:Class ; rdfs:label "intestinal amyloidosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_34 . obo:MPATH_767 obo:IAO_0000115 "A Meckel's diverticulum is a pouch on the wall of the lower part of the intestine that is present at birth."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T07:05:54Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:767"^^xsd:string ; a owl:Class ; rdfs:label "Meckel's diverticulum"^^xsd:string ; rdfs:subClassOf obo:MPATH_68 . obo:MPATH_768 obo:IAO_0000115 "Necrosis associated with or caused by local bacterial infection."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T07:11:40Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:768"^^xsd:string ; a owl:Class ; rdfs:label "septic necrosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_4 . obo:MPATH_769 obo:IAO_0000115 "Necrosis of the uterine wall with large bacterial colonies on its surface."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T07:15:32Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:769"^^xsd:string ; a owl:Class ; rdfs:label "uterine septic necrosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_768 . obo:MPATH_77 obo:IAO_0000115 "Stricto sensu: replacement of one body part or tissue by an homologous structure or tissue, but commonly used incorrectly to describe non-homologous transformations better described as heterotopias or ectopias."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:77"^^xsd:string ; a owl:Class ; rdfs:label "homoeotic change"^^xsd:string ; rdfs:subClassOf obo:MPATH_599 . obo:MPATH_770 obo:IAO_0000115 "Abnormal organ dimensions or weight"^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T07:19:32Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:770"^^xsd:string ; a owl:Class ; rdfs:label "abnormal organ size"^^xsd:string ; rdfs:subClassOf obo:MPATH_86 . obo:MPATH_771 obo:IAO_0000115 "Abnormality of extent of the normal long axis"^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T07:21:06Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:771"^^xsd:string ; a owl:Class ; rdfs:label "abnormal organ length"^^xsd:string ; rdfs:subClassOf obo:MPATH_770 . obo:MPATH_772 obo:IAO_0000115 "Abnormal mass of organ"^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T07:22:00Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:772"^^xsd:string ; a owl:Class ; rdfs:label "abnormal organ mass"^^xsd:string ; rdfs:subClassOf obo:MPATH_770 . obo:MPATH_773 obo:IAO_0000115 "Abnormal length of the intestine."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T07:22:44Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:773"^^xsd:string ; a owl:Class ; rdfs:label "abnormal intestine length"^^xsd:string ; rdfs:subClassOf obo:MPATH_771 . obo:MPATH_774 obo:IAO_0000115 "Focal necrosis in the liver often but not always associated with thrombosis."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T07:24:44Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:774"^^xsd:string ; a owl:Class ; rdfs:label "focal hepatic coagulative necrosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_7 . obo:MPATH_775 obo:IAO_0000115 "Exertion of abnormal force on a structure or structures usually resulting in deformation and damage."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T07:27:38Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:775"^^xsd:string ; a owl:Class ; rdfs:label "compression"^^xsd:string ; rdfs:subClassOf obo:MPATH_15 . obo:MPATH_776 obo:IAO_0000115 "A spermatocoele is a cyst that contains spermatozoa. ."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T07:30:33Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:776"^^xsd:string ; a owl:Class ; rdfs:comment "They occur in the head of the epididymis or less commonly, in the spermatic cord."^^xsd:string ; rdfs:label "spermatocoele"^^xsd:string ; rdfs:subClassOf obo:MPATH_62 . obo:MPATH_777 obo:IAO_0000115 "Formation of urinary concretions in any part of the kidney."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T07:32:55Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:777"^^xsd:string ; a owl:Class ; rdfs:label "urelithiasis"^^xsd:string ; rdfs:subClassOf obo:MPATH_614 . obo:MPATH_778 obo:IAO_0000115 "https://doi.org/10.1038/srep41807"^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T07:34:59Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:778"^^xsd:string ; a owl:Class ; rdfs:label "corpora amylacea"^^xsd:string ; rdfs:subClassOf obo:MPATH_614 . obo:MPATH_779 obo:IAO_0000115 "Formation or urinary concretions in the ureter."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T07:36:04Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:779"^^xsd:string ; a owl:Class ; rdfs:label "uretolithiasis"^^xsd:string ; rdfs:subClassOf obo:MPATH_777 . obo:MPATH_78 obo:IAO_0000115 "Incomplete closure of a void or lumen due to failure of growth or fusion of bounding walls."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:78"^^xsd:string ; a owl:Class ; rdfs:label "incomplete closure"^^xsd:string ; rdfs:subClassOf obo:MPATH_599 . obo:MPATH_780 obo:IAO_0000115 "Pseudoxanthoma elasticum is a progressive disorder characterized by accumulated deposits of calcium and other minerals in elastic fibers."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T07:38:35Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:780"^^xsd:string ; a owl:Class ; rdfs:label "pseudoxanthoma elasticum"^^xsd:string ; rdfs:subClassOf obo:MPATH_36 . obo:MPATH_781 obo:IAO_0000115 "Softening of brain tissue, usually caused by vascular insufficiency or degenerative changes."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T07:43:13Z"^^xsd:string ; oboInOwl:hasExactSynonym "cerebromalacia"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:781"^^xsd:string ; a owl:Class ; rdfs:comment "Areas in the brain where the parenchyma is blanched. Cells in this area are pycnotic. This may be the sequela of an infarction."^^xsd:string ; rdfs:label "encephalomalacia"^^xsd:string ; rdfs:subClassOf obo:MPATH_25 . obo:MPATH_782 obo:IAO_0000115 "Collapse of the eye globe associated with degenerative changes."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T07:51:11Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:782"^^xsd:string ; a owl:Class ; rdfs:label "phthisis bulbi"^^xsd:string ; rdfs:subClassOf obo:MPATH_25 . obo:MPATH_783 obo:IAO_0000115 "Follicular dystrophy, rupture, foreign body reaction, ulceration, scarring, pseudoepitheliomatous hyperplasia are part of a syndrome commonly called B6 dermatitis in black strains of mice."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T07:55:07Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:783"^^xsd:string ; a owl:Class ; rdfs:label "B6 dermatitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_196 . obo:MPATH_784 obo:IAO_0000115 "Degeneration and resorption of an ovarian follicle before it reaches maturity and ruptures."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T07:59:53Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:784"^^xsd:string ; a owl:Class ; rdfs:comment "Included here to permit annotation of unusual patterns or atresia; abnormal numbers of atretic follicles or abnoral size or distribution."^^xsd:string ; rdfs:label "follicular atresia"^^xsd:string ; rdfs:subClassOf obo:MPATH_25 . obo:MPATH_785 obo:IAO_0000115 "Marked production of granulocytes, primarily neutrophils, usually in response to a major acute inflammatory response."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T08:06:16Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:785"^^xsd:string ; a owl:Class ; rdfs:label "bone marrow granulopoiesis"^^xsd:string ; rdfs:subClassOf obo:MPATH_188 . obo:MPATH_786 obo:IAO_0000115 "The drying, thickening and coagulation of extracellular secretions or fluids."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T08:09:33Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:786"^^xsd:string ; a owl:Class ; rdfs:label "inspissation"^^xsd:string ; rdfs:subClassOf obo:MPATH_15 . obo:MPATH_787 obo:IAO_0000115 "Ventral prolapse of the intervertebral disk."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T08:37:59Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:787"^^xsd:string ; a owl:Class ; rdfs:comment "Ventral prolapse is quite rare but found in ageing mice."^^xsd:string ; rdfs:label "intervertebral disk prolapse ventral"^^xsd:string ; rdfs:subClassOf obo:MPATH_742 . obo:MPATH_788 obo:IAO_0000115 "The testicle twisted around the vascular tract to constrict flow resulting in liquifactive necrosis of the affected testicle."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T08:43:39Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:788"^^xsd:string ; a owl:Class ; rdfs:label "testicular torsion"^^xsd:string ; rdfs:subClassOf obo:MPATH_562 . obo:MPATH_789 obo:IAO_0000115 "Dermal granuloma surrounding hair fibers."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T08:52:38Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:789"^^xsd:string ; a owl:Class ; rdfs:label "trichogranuloma"^^xsd:string ; rdfs:subClassOf obo:MPATH_847 . obo:MPATH_79 obo:IAO_0000115 "Abnormal position or orientation of a structure insufficient to be called a heterotopia."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Misplacement"^^xsd:string ; oboInOwl:id "MPATH:79"^^xsd:string ; a owl:Class ; rdfs:label "malposition"^^xsd:string ; rdfs:subClassOf obo:MPATH_76 . obo:MPATH_790 obo:IAO_0000115 "Retinal degeneration of both eyes."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T08:56:45Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:790"^^xsd:string ; a owl:Class ; rdfs:label "bilateral retinal degeneration"^^xsd:string ; rdfs:subClassOf obo:MPATH_737 . obo:MPATH_791 obo:IAO_0000115 "Occlusion of a vessel by a piece of dissected cartilage."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T09:27:08Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:791"^^xsd:string ; a owl:Class ; rdfs:label "cartilagenous embolism"^^xsd:string ; rdfs:subClassOf obo:MPATH_110 . obo:MPATH_792 obo:IAO_0000115 "Proliferation of the reticuloendothelial cells in the medulla of the lymph node."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T09:32:12Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:792"^^xsd:string ; a owl:Class ; rdfs:label "lymph node reticuloendothelial cell hyperplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_602 . obo:MPATH_793 obo:IAO_0000115 "An increase in the size of the spleen due to ongoing acute or chronic infection."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T09:42:26Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:793"^^xsd:string ; a owl:Class ; rdfs:label "reactive splenomegaly"^^xsd:string ; rdfs:subClassOf obo:MPATH_188 . obo:MPATH_794 obo:IAO_0000115 "Digested blood in the lumen of the stomach or small intestine, indicative of hemorrhage."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T09:57:01Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:794"^^xsd:string ; a owl:Class ; rdfs:label "melena"^^xsd:string ; rdfs:subClassOf obo:MPATH_119 . obo:MPATH_795 obo:IAO_0000115 "Round , often laminar, non-proteinaceous eosinophilic bodies representing calcium deposition."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T10:01:09Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:795"^^xsd:string ; a owl:Class ; rdfs:comment "Psammoma bodies are associated with the papillary (nipple-like) histomorphology and are thought to arise from (1) the infarction and calcification of papillae tips and (2) calcification of intralymphatic tumor thrombi."^^xsd:string ; rdfs:label "psammoma body"^^xsd:string ; rdfs:subClassOf obo:MPATH_36 . obo:MPATH_796 obo:IAO_0000115 "Lack of sperm."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T10:10:45Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:796"^^xsd:string ; a owl:Class ; rdfs:comment "May be through failure of spermatogenesis, or increased death."^^xsd:string ; rdfs:label "aspermia"^^xsd:string ; rdfs:subClassOf obo:MPATH_797 . obo:MPATH_797 obo:IAO_0000115 "Compromise or abnormality of the process of spermatogenesis"^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T10:17:11Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:797"^^xsd:string ; a owl:Class ; rdfs:label "spermatogenesis defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_604 . obo:MPATH_798 obo:IAO_0000115 "Reduced numbers of sperm."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T10:18:26Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:798"^^xsd:string ; a owl:Class ; rdfs:label "hypospermia"^^xsd:string ; rdfs:subClassOf obo:MPATH_797 . obo:MPATH_799 obo:IAO_0000115 "scoliosis is an abnormal curvature of the spine. The spine curves away from the middle or sideways."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-02T10:20:56Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:799"^^xsd:string ; a owl:Class ; rdfs:label "scoliosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_871 . obo:MPATH_8 obo:IAO_0000115 "Dead and dying adipose tissue, characterized by the formation of small gray or white foci of soapy (saponified) cellular debris."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:8"^^xsd:string ; a owl:Class ; rdfs:label "fat necrosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_4 . obo:MPATH_80 obo:IAO_0000115 "Occlusion ( partial or complete) of a lumen or space, internally by a space occupying mass or, in the case of stenosis, by local reduction in the diameter of a vessel, duct or the intestine."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:80"^^xsd:string ; a owl:Class ; rdfs:label "obstruction and stenosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_56 . obo:MPATH_800 obo:IAO_0000115 "Dorsal prolapse of the intervertebral disk."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-03T07:08:38Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:800"^^xsd:string ; a owl:Class ; rdfs:label "intervertebral disk prolapse dorsal"^^xsd:string ; rdfs:subClassOf obo:MPATH_742 . obo:MPATH_801 obo:IAO_0000115 "Presence of dorsal and ventrally prolapsed disks in the same vertebral column."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-03T07:09:46Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:801"^^xsd:string ; a owl:Class ; rdfs:label "intervertebral disks prolapsed dorsally and ventrally"^^xsd:string ; rdfs:subClassOf obo:MPATH_742 . obo:MPATH_802 obo:IAO_0000115 "Eversion through the anus."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-03T07:11:38Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:802"^^xsd:string ; a owl:Class ; rdfs:label "rectal prolapse"^^xsd:string ; rdfs:subClassOf obo:MPATH_626 . obo:MPATH_803 obo:IAO_0000115 "Thickening of trabecular bone."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-03T07:41:18Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:803"^^xsd:string ; a owl:Class ; rdfs:comment "Not osteopetrosis."^^xsd:string ; rdfs:label "trabecular bone thickening"^^xsd:string ; rdfs:subClassOf obo:MPATH_126 . obo:MPATH_804 obo:IAO_0000115 "Large numbers of thin-walled dilated lymphatic channels situated in the dermis, subcutis or skeletal muscle."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-25T03:58:53Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:804"^^xsd:string ; a owl:Class ; rdfs:comment "This is a developmental malformation"^^xsd:string ; rdfs:label "cavernous lymphangioma"^^xsd:string ; rdfs:subClassOf obo:MPATH_420 . obo:MPATH_805 obo:IAO_0000115 "Variant of cavernous lymphangioma (MPATH:804) showing gross dilatation of lymphatic channels."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-25T04:01:26Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Cystic lymphangioma."^^xsd:string ; oboInOwl:id "MPATH:805"^^xsd:string ; a owl:Class ; rdfs:label "cystic hygroma"^^xsd:string ; rdfs:subClassOf obo:MPATH_420 . obo:MPATH_806 obo:IAO_0000115 "Cutaneous grouped collection of thin-walled translucent vessels, which appear at birth or in early infancy and are commonest around the limb girdles."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-25T04:03:31Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:806"^^xsd:string ; a owl:Class ; rdfs:comment "Generally believed to represent a developmental defect but may be associated with surgery."^^xsd:string ; rdfs:label "lymphangioma circumscriptum"^^xsd:string ; rdfs:subClassOf obo:MPATH_420 . obo:MPATH_807 obo:IAO_0000115 "Large cystic subcutaneous spaces usually found in the flexures, especially around the neck."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-25T04:11:06Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Cystic hygroma"^^xsd:string ; oboInOwl:id "MPATH:807"^^xsd:string ; a owl:Class ; rdfs:comment "Obstruction of the developing lymphatics may contribute to their genesis."^^xsd:string ; rdfs:label "hygroma"^^xsd:string ; rdfs:subClassOf obo:MPATH_62 . obo:MPATH_808 obo:IAO_0000115 "Accumulation of interstitial fluid caused by blockage or failure of the lymphatic system."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-25T04:15:32Z"^^xsd:string ; oboInOwl:hasExactSynonym "Lymphoedema"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:808"^^xsd:string ; a owl:Class ; rdfs:comment "Not be confused with edema arising from venous insufficiency, which is not lymphedema."^^xsd:string ; rdfs:label "lymphedema"^^xsd:string ; rdfs:subClassOf obo:MPATH_109 . obo:MPATH_809 obo:IAO_0000115 "Edema of the posterior aspect of the fetal neck caused by an accumulation of fluid, usually lymph."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-25T04:33:15Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:809"^^xsd:string ; a owl:Class ; rdfs:label "nuchal edema"^^xsd:string ; rdfs:subClassOf obo:MPATH_109 . obo:MPATH_81 obo:IAO_0000115 "Presence of a hole/channel through a normally imperforate structure often a membrane or septum."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:81"^^xsd:string ; a owl:Class ; rdfs:label "perforation"^^xsd:string ; rdfs:subClassOf obo:MPATH_56 . obo:MPATH_810 obo:IAO_0000115 "Degenerative changes in hair follicles resulting in a deformed hair fiber, sometimes root sheath hyperplasia and follicular rupture."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2011-11-25T05:04:59Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:810"^^xsd:string ; a owl:Class ; rdfs:label "follicular dystrophy"^^xsd:string ; rdfs:subClassOf obo:MPATH_554 . obo:MPATH_811 obo:IAO_0000115 "Deposition of minerals in the epicardium."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-19T03:53:35Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:811"^^xsd:string ; a owl:Class ; rdfs:label "epicardial mineralization"^^xsd:string ; rdfs:subClassOf obo:MPATH_555 . obo:MPATH_812 obo:IAO_0000115 "A collection of fluid underneath the top layer of skin (epidermis)."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-19T03:59:12Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:812"^^xsd:string ; a owl:Class ; rdfs:comment "Most blisters are filled with a clear fluid called serum or plasma. However, blisters can be filled with blood (known as blood blisters) or with pus (if they become infected)."^^xsd:string ; rdfs:label "blister"^^xsd:string ; rdfs:subClassOf obo:MPATH_1 . obo:MPATH_813 obo:IAO_0000115 "Lesions of a connective tissue disease causing blisters in the skin and mucosal membranes."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-19T04:02:20Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:813"^^xsd:string ; a owl:Class ; rdfs:label "epidermolysis bullosa lesions"^^xsd:string ; rdfs:subClassOf obo:MPATH_812 . obo:MPATH_814 obo:IAO_0000115 "Locally circumscribed regions of fatty change."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-19T04:10:23Z"^^xsd:string ; oboInOwl:hasExactSynonym "focal fatty change"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:814"^^xsd:string ; a owl:Class ; rdfs:label "focal hepatic lipidosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_622 . obo:MPATH_815 obo:IAO_0000115 "subtype of steatosis with Hepatocytes containing a large well-defined single rounded vacuole within each cell, nucleus and cytoplasm displaced to the periphery,"^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-19T04:13:31Z"^^xsd:string ; oboInOwl:hasExactSynonym "macrovesicular steatosis"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:815"^^xsd:string ; a owl:Class ; rdfs:label "macrovesicular lipidosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_622 . obo:MPATH_816 obo:IAO_0000115 """Variant form of hepatic steatosis. Hepatocytes partially or completely filled with numerous small lipid vacuoles. Affected hepatocytes may have a foamy appearance.Small vacuoles do not normally displace the nucleus to the periphery in contrast to macrovesicular lipidosis."""^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-19T04:18:42Z"^^xsd:string ; oboInOwl:hasExactSynonym "microvesicular fatty change"^^xsd:string, "microvesicular steatosis"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:816"^^xsd:string ; a owl:Class ; rdfs:label "microvesicular lipidosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_622 . obo:MPATH_817 obo:IAO_0000115 "Form of degenerative process in which there is Intracytoplasmic fluid accumulation secondary to disturbance of cell membrane integrity."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-19T04:26:38Z"^^xsd:string ; oboInOwl:hasExactSynonym "cloudy swelling"^^xsd:string, "hydropic change"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym ""^^xsd:string ; oboInOwl:id "MPATH:817"^^xsd:string ; a owl:Class ; rdfs:comment "Cytoplasmic vacuolation and ballooning with a centrally located nucleus."^^xsd:string ; rdfs:label "hydropic degeneration"^^xsd:string ; rdfs:subClassOf obo:MPATH_15 . obo:MPATH_818 oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-19T04:37:02Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:818"^^xsd:string ; a owl:Class ; rdfs:label "focal pulmonary histiocytosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_652 . obo:MPATH_819 oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-19T04:39:04Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:819"^^xsd:string ; a owl:Class ; rdfs:label "focal renal pelvic mineralisation."^^xsd:string ; rdfs:subClassOf obo:MPATH_555 . obo:MPATH_82 obo:IAO_0000115 "Persistence of an embryonic structure or tissue into the post-natal period in its normal location; (Chronological/temporal anomaly)."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Embryonic rest."^^xsd:string ; oboInOwl:id "MPATH:82"^^xsd:string ; a owl:Class ; rdfs:label "persistent embryonic structure"^^xsd:string ; rdfs:subClassOf obo:MPATH_56 . obo:MPATH_820 obo:IAO_0000115 "Increase in size of the thyroid gland caused initially by uniform follicular epithelial hyperplasia generally in response to iodine deficiency."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-19T05:09:58Z"^^xsd:string ; oboInOwl:hasExactSynonym "goiter"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "hyperplastic goitre"^^xsd:string ; oboInOwl:id "MPATH:820"^^xsd:string ; a owl:Class ; rdfs:label "goitre"^^xsd:string ; rdfs:subClassOf obo:MPATH_602 . obo:MPATH_821 obo:IAO_0000115 "Tissue showing smaller mass as a consequence of deficient proliferation or premature differentiation."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-19T05:20:21Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:821"^^xsd:string ; a owl:Class ; rdfs:label "hypoplastic tissue"^^xsd:string ; rdfs:subClassOf obo:MPATH_126 . obo:MPATH_822 obo:IAO_0000115 "Reduced mass of GALT resulting form fewer cells."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-19T05:21:50Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:822"^^xsd:string ; a owl:Class ; rdfs:label "hypoplastic gut associated lymphoid tissue"^^xsd:string ; rdfs:subClassOf obo:MPATH_821 . obo:MPATH_823 obo:IAO_0000115 "A benign neoplasm characterized by mucous and fibroblastic tissues."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-20T11:45:41Z"^^xsd:string ; oboInOwl:hasExactSynonym "Fibromyxoma"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "fibroma myxomatodes."^^xsd:string ; oboInOwl:id "MPATH:823"^^xsd:string ; a owl:Class ; rdfs:label "myxofibroma"^^xsd:string ; rdfs:subClassOf obo:MPATH_407 . obo:MPATH_824 obo:IAO_0000115 "A benign localized neoplasm arising from the subcutaneous tissues and skeletal muscle. It is characterized by the presence of myofibroblastic hyperchromatic spindle cells, hylanized stroma formation, calcification, necrosis, and a multinodular growth pattern."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-20T11:51:59Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Solitary Myofibromatosis"^^xsd:string ; oboInOwl:id "MPATH:824"^^xsd:string ; a owl:Class ; rdfs:label "myofibroma"^^xsd:string ; rdfs:subClassOf obo:MPATH_407 . obo:MPATH_825 obo:IAO_0000115 "Generation of intracytoplasmic vacuoles otherwise unspecified."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-22T08:19:10Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:825"^^xsd:string ; a owl:Class ; rdfs:label "vacuolation"^^xsd:string ; rdfs:subClassOf obo:MPATH_15 . obo:MPATH_826 obo:IAO_0000115 "granulomatous inflammation of the skin"^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-22T08:22:17Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:826"^^xsd:string ; a owl:Class ; rdfs:label "granulomatous dermatitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_215 . obo:MPATH_827 obo:IAO_0000115 "chronic inflammation of the skin"^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-22T08:24:43Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:827"^^xsd:string ; a owl:Class ; rdfs:label "chronic dermatitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_214 . obo:MPATH_828 obo:IAO_0000115 "locally demarcated region of inflammation in the skin"^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-22T08:33:42Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:828"^^xsd:string ; a owl:Class ; rdfs:label "focal dermatitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_196 . obo:MPATH_829 obo:IAO_0000115 "possession of both ovary and testis due to primary sex determination defect"^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-22T08:42:35Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:829"^^xsd:string ; a owl:Class ; rdfs:label "true hermaphrodite"^^xsd:string ; rdfs:subClassOf obo:MPATH_86 . obo:MPATH_83 obo:IAO_0000115 "Any defect in the formation of septae not describable as perforation."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:83"^^xsd:string ; a owl:Class ; rdfs:label "septation defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_56 . obo:MPATH_830 obo:IAO_0000115 "repair, reproduction, or replacement of lost or injured cells, tissues, or organs."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-22T08:45:44Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:830"^^xsd:string ; a owl:Class ; rdfs:label "regeneration"^^xsd:string ; rdfs:subClassOf obo:MPATH_604 . obo:MPATH_831 obo:IAO_0000115 "multilocular sites of muscle regeneration with centrally located nuclei."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-22T08:48:14Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:831"^^xsd:string ; a owl:Class ; rdfs:label "multifocal muscle regeneration"^^xsd:string ; rdfs:subClassOf obo:MPATH_830 . obo:MPATH_832 obo:IAO_0000115 "persistent retraction of the prepuce behind the glans penis"^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-22T08:52:08Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:832"^^xsd:string ; a owl:Class ; rdfs:comment "generally due to inflammation, but can cause further inflammation which exacerbates the condition"^^xsd:string ; rdfs:label "paraphimosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_56 . obo:MPATH_833 obo:IAO_0000115 "transition between acute and chronic inflammation."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-22T08:55:14Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:833"^^xsd:string ; a owl:Class ; rdfs:comment "time varies form a few days to a week or so. Cells mainly lymphocytes and plasma cells, few macrophages or neutrophils. Less hemorrhage, edema and hyperemia."^^xsd:string ; rdfs:label "subacute inflammation"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_834 obo:IAO_0000115 "non-malignant neoplasia of the ovary."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-22T09:04:54Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "tubular adenoma"^^xsd:string ; oboInOwl:id "MPATH:834"^^xsd:string ; a owl:Class ; rdfs:label "ovarian tubulostromal tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_556 . obo:MPATH_835 obo:IAO_0000115 "acute inflammation due to infection."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-22T03:38:07Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:835"^^xsd:string ; a owl:Class ; rdfs:label "acute septic inflammation"^^xsd:string ; rdfs:subClassOf obo:MPATH_213 . obo:MPATH_836 obo:IAO_0000115 "fibrosis in the skin"^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-22T05:06:25Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:836"^^xsd:string ; a owl:Class ; rdfs:label "dermal fibrosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_181 . obo:MPATH_837 obo:IAO_0000115 "Fatty change in the mid-zonal region of the liver."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-22T05:23:46Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:837"^^xsd:string ; a owl:Class ; rdfs:label "hepatic mid-zonal fatty metamorphosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_622 . obo:MPATH_838 obo:IAO_0000115 "carcinoma with an absence of epithelial structural differentiation."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-22T05:26:31Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:838"^^xsd:string ; a owl:Class ; rdfs:label "anaplastic carcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_549 . obo:MPATH_839 obo:IAO_0000115 "anaplastic carcinoma of the liver."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-22T05:28:22Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:839"^^xsd:string ; a owl:Class ; rdfs:label "anaplastic hepatocellular carcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_357, obo:MPATH_838 . obo:MPATH_84 obo:IAO_0000115 "Additional structure whether normally located or not."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:84"^^xsd:string ; a owl:Class ; rdfs:label "supernumerary structure"^^xsd:string ; rdfs:subClassOf obo:MPATH_67 . obo:MPATH_840 obo:IAO_0000115 "arthitis involving extensive macrophage infiltration into the joint."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-22T05:37:23Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:840"^^xsd:string ; a owl:Class ; rdfs:label "granulomatous arthritis"^^xsd:string ; rdfs:subClassOf obo:MPATH_195, obo:MPATH_215 . obo:MPATH_841 obo:IAO_0000115 "Absence of eye."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-22T05:40:44Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:841"^^xsd:string ; a owl:Class ; rdfs:comment "may be uni or bilateral"^^xsd:string ; rdfs:label "anopthalmia"^^xsd:string ; rdfs:subClassOf obo:MPATH_86 . obo:MPATH_842 obo:IAO_0000115 "abnormally shaped vertebral body often triangular as opposed to rectangular."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-22T05:55:21Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:842"^^xsd:string ; a owl:Class ; rdfs:comment "spontaneous or induced developmental lesion"^^xsd:string ; rdfs:label "coccygeal hemivertebrae"^^xsd:string ; rdfs:subClassOf obo:MPATH_67 . obo:MPATH_843 obo:IAO_0000115 "Cessation of movement of a body fluid or liquid."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-22T06:05:28Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:843"^^xsd:string ; a owl:Class ; rdfs:label "stasis"^^xsd:string ; rdfs:subClassOf obo:MPATH_80 . obo:MPATH_844 obo:IAO_0000115 "Cessation of the flow of bile due to bile duct blockage or overproduction."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-22T06:06:41Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:844"^^xsd:string ; a owl:Class ; rdfs:label "biliary stasis"^^xsd:string ; rdfs:subClassOf obo:MPATH_843 . obo:MPATH_845 obo:IAO_0000115 "Evidence of residual placenta in utero without embryo."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-24T03:03:26Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:845"^^xsd:string ; a owl:Class ; rdfs:label "partial abortion"^^xsd:string ; rdfs:subClassOf obo:MPATH_100 . obo:MPATH_846 obo:IAO_0000115 "acute inflammation of the footpad caused by foreign body."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-24T03:05:46Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:846"^^xsd:string ; a owl:Class ; rdfs:label "foreign body acute pododermatitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_659 . obo:MPATH_847 obo:IAO_0000115 "Collection of epithelioid macrophages into a nodule"^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-24T03:19:38Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:847"^^xsd:string ; a owl:Class ; rdfs:label "granuloma"^^xsd:string ; rdfs:subClassOf obo:MPATH_215 . obo:MPATH_848 obo:IAO_0000115 "Replacement of normal tissue by granuloma."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-24T03:22:52Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:848"^^xsd:string ; a owl:Class ; rdfs:label "effacing granuloma"^^xsd:string ; rdfs:subClassOf obo:MPATH_847 . obo:MPATH_849 obo:IAO_0000115 "poorly differentiated adenocarcinoma of the mammary gland"^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-24T03:26:01Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:849"^^xsd:string ; a owl:Class ; rdfs:label "anaplastic mammary adenocarcinoma"^^xsd:string ; rdfs:subClassOf obo:MPATH_268 . obo:MPATH_85 obo:IAO_0000115 "Alteration in the differentiation of a cell or tissue already showing a different, recognisable, differentiated state."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:85"^^xsd:string ; a owl:Class ; rdfs:comment "This term is generally used in the context of embryonic cells or stem cells."^^xsd:string ; rdfs:label "transdifferentiation"^^xsd:string ; rdfs:subClassOf obo:MPATH_599 . obo:MPATH_850 obo:IAO_0000115 "Morphological abnormality following trauma or related insult such as infection."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-24T03:28:03Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:850"^^xsd:string ; a owl:Class ; rdfs:label "post-traumatic structural abnormality"^^xsd:string ; rdfs:subClassOf obo:MPATH_56 . obo:MPATH_851 obo:IAO_0000115 "acquired dysmorphology of the external pinna following trauma or infection."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-24T03:29:48Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:851"^^xsd:string ; a owl:Class ; rdfs:label "auricular deformation"^^xsd:string ; rdfs:subClassOf obo:MPATH_850 . obo:MPATH_852 obo:IAO_0000115 "A condition in which there is an unusually large proportion of plasma cells in tissues, exudates, or blood."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-24T03:32:23Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:852"^^xsd:string ; a owl:Class ; rdfs:label "plasmacytosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_194 . obo:MPATH_853 obo:IAO_0000115 "Abnormality of circulating plasma cells"^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-24T03:33:57Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:853"^^xsd:string ; a owl:Class ; rdfs:label "systemic plasmacytosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_852 . obo:MPATH_854 obo:IAO_0000115 "Plasmacytosis in the skin."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-24T03:35:42Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:854"^^xsd:string ; a owl:Class ; rdfs:label "cutaneous plasmacytosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_852 . obo:MPATH_855 obo:IAO_0000115 "In vivo formation of intensely eosinophilic material (radiate, star-like, asteroid or club-shaped configurations) around microorganisms (fungi, bacteria and parasites) or biologically inert substances."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-24T03:38:37Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:855"^^xsd:string ; a owl:Class ; rdfs:label "Splendore-Hoeppli phenomenon"^^xsd:string ; rdfs:subClassOf obo:MPATH_194 . obo:MPATH_856 obo:IAO_0000115 "Rupture of alveolar walls result in large rounded open air spaces in the lung"^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-24T03:43:52Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:856"^^xsd:string ; a owl:Class ; rdfs:label "bullous emphysema"^^xsd:string ; rdfs:subClassOf obo:MPATH_31 . obo:MPATH_857 obo:IAO_0000115 "mutilocular bullous emphysema"^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-24T03:45:01Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:857"^^xsd:string ; a owl:Class ; rdfs:label "multifocal bullous emphysema"^^xsd:string ; rdfs:subClassOf obo:MPATH_856 . obo:MPATH_858 obo:IAO_0000115 "Benign proliferation of capillaries made up of closely packed aggregations of capillaries, usually of normal caliber, separated by scant connective stroma."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-24T03:46:38Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:858"^^xsd:string ; a owl:Class ; rdfs:comment "Most common kind of hemangioma thought to be derived from primitive mesenchymal stem cells."^^xsd:string ; rdfs:label "capillary hemangioma"^^xsd:string ; rdfs:subClassOf obo:MPATH_240 . obo:MPATH_859 obo:IAO_0000115 "Chronic granulomatous bacterial infection that affects the skin, and sometimes the viscera. Usually caused by S. aureus."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-24T03:52:35Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:859"^^xsd:string ; a owl:Class ; rdfs:label "botryomycosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_627 . obo:MPATH_86 obo:IAO_0000115 "Developmental defect characteristic of a particular organ or organ system which may be a recognised syndrome or a complex defect showing multiple manifestations."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:86"^^xsd:string ; a owl:Class ; rdfs:label "organ specific developmental defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_55 . obo:MPATH_860 obo:IAO_0000115 "inflammation of the gall bladder"^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-24T04:11:00Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:860"^^xsd:string ; a owl:Class ; rdfs:label "cholecystitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_861 obo:IAO_0000115 "cholecystitis associated with edema"^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-24T04:11:43Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:861"^^xsd:string ; a owl:Class ; rdfs:label "edematous cholecystitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_860 . obo:MPATH_862 obo:IAO_0000115 "Accumulation or trapping of air"^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-24T04:17:10Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:862"^^xsd:string ; a owl:Class ; rdfs:label "flatus"^^xsd:string ; rdfs:subClassOf obo:MPATH_33 . obo:MPATH_863 obo:IAO_0000115 "circumscribed ulceration of the skin penetrating the basement membrane as part of inflammation process."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-24T04:18:54Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:863"^^xsd:string ; a owl:Class ; rdfs:label "focal ulcerative dermatitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_196 . obo:MPATH_864 obo:IAO_0000115 "Inflammation of the outer ear."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-25T10:00:59Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:864"^^xsd:string ; a owl:Class ; rdfs:label "otitis externa"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_865 obo:IAO_0000115 "Papillomatous inflammation of the tongue caused by a foreign body."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-25T10:49:17Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:865"^^xsd:string ; a owl:Class ; rdfs:label "foreign body acute papillomatous glossitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_662 . obo:MPATH_866 obo:IAO_0000115 "Thickening of the glandular epithelium"^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-25T10:59:20Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:866"^^xsd:string ; a owl:Class ; rdfs:comment "Often with crystalloid formation"^^xsd:string ; rdfs:label "gastric adenomatous hyperplasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_138 . obo:MPATH_867 obo:IAO_0000115 "Major hepatic vein surrounded by fibrous connective tissue."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-25T11:02:20Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:867"^^xsd:string ; a owl:Class ; rdfs:label "hepatic central vein perivascular fibrosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_181 . obo:MPATH_868 obo:IAO_0000115 "Dilation of the uterus"^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-25T11:58:56Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "hydrometra"^^xsd:string ; oboInOwl:id "MPATH:868"^^xsd:string ; a owl:Class ; rdfs:comment "Usually assciated iwth hydrpometra"^^xsd:string ; rdfs:label "uterine ectasia"^^xsd:string ; rdfs:subClassOf obo:MPATH_474 . obo:MPATH_869 obo:IAO_0000115 "Condition in which a part of the intestine has invaginated into another section of intestine,"^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-25T12:04:33Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:869"^^xsd:string ; a owl:Class ; rdfs:label "intussception"^^xsd:string ; rdfs:subClassOf obo:MPATH_56 . obo:MPATH_87 obo:IAO_0000115 "Abnormal morphology, differentiation or location of primordial germ cells or their descendents. Not neoplastic."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:87"^^xsd:string ; a owl:Class ; rdfs:label "germ cell defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_86 . obo:MPATH_870 obo:IAO_0000115 "severe type of the disorder generally apparent at birth.Junctional epidermolysis bullosa involves defects in hemidesmosomes. t"^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-25T12:10:57Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:870"^^xsd:string ; a owl:Class ; rdfs:label "junctional epidermolysis bullosa"^^xsd:string ; rdfs:subClassOf obo:MPATH_813 . obo:MPATH_871 obo:IAO_0000115 "Structural defects of the bony and muscular components of the vertebrae."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-25T12:15:53Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:871"^^xsd:string ; a owl:Class ; rdfs:label "spinal structural defects"^^xsd:string ; rdfs:subClassOf obo:MPATH_86 . obo:MPATH_872 obo:IAO_0000115 "Abnormality of the kyphotic curvature of the spine."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-25T12:17:10Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:872"^^xsd:string ; a owl:Class ; rdfs:label "kyphosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_871 . obo:MPATH_873 obo:IAO_0000115 "Reduced size of the eye globe."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-03-25T12:21:30Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:873"^^xsd:string ; a owl:Class ; rdfs:label "micropthalmia"^^xsd:string ; rdfs:subClassOf obo:MPATH_770 . obo:MPATH_874 obo:IAO_0000115 "Plasmacytosis is a hyperplastic condition in which there is an unusually large proportion of mature plasma cells in tissues, exudates, or blood."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-09-03T04:32:06Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:874"^^xsd:string ; a owl:Class ; rdfs:label "plasmacytosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_602 . obo:MPATH_875 obo:IAO_0000115 "cutaneous manifestation of plasmacytosis"^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-09-03T04:36:31Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:875"^^xsd:string ; a owl:Class ; rdfs:label "cutaneous plasmacytosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_874 . obo:MPATH_876 obo:IAO_0000115 "systemic manifestation of plasmacytosis. Disseminated in the circulation."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-09-03T04:37:32Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:876"^^xsd:string ; a owl:Class ; rdfs:label "systemic plasmacytosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_874 . obo:MPATH_877 obo:IAO_0000115 "An inflammatory condition of the lung, especially affecting the alveoli, associated with fever, chest symptoms, and congestion."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-09-03T05:30:23Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:877"^^xsd:string ; a owl:Class ; rdfs:comment "Typically caused by an infection but there are a number of other causes. Infectious agents include: bacteria, viruses, fungi, and parasites."^^xsd:string ; rdfs:label "pneumonia"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_878 obo:IAO_0000115 "Pneumonia caused by aspiration of a foreign body."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-09-03T05:34:45Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:878"^^xsd:string ; a owl:Class ; rdfs:label "foreign body aspiration pneumonia"^^xsd:string ; rdfs:subClassOf obo:MPATH_877 . obo:MPATH_879 obo:IAO_0000115 "Inflammation of the tooth gum"^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-09-03T05:37:29Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:879"^^xsd:string ; a owl:Class ; rdfs:label "gingivitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_88 obo:IAO_0000115 "nephroblastomatosis"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:88"^^xsd:string ; a owl:Class ; rdfs:comment "Obsolete - subsumed into MPATH:82"^^xsd:string ; rdfs:label "nephroblastomatosis"^^xsd:string ; owl:deprecated true . obo:MPATH_880 obo:IAO_0000115 "inflammation of the tooth gum caused by a foreign body."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-09-03T05:38:14Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:880"^^xsd:string ; a owl:Class ; rdfs:comment "Generally caused by hair or food debris"^^xsd:string ; rdfs:label "foreign body gingivitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_879 . obo:MPATH_881 obo:IAO_0000115 "Fibrotic reaction to presence of a foreign body."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-09-03T05:44:35Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:881"^^xsd:string ; a owl:Class ; rdfs:label "reactive fibrosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_181 . obo:MPATH_882 obo:IAO_0000115 "Inflammatory cell infiltrate around bile ducts within the liver."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-09-04T11:07:32Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:882"^^xsd:string ; a owl:Class ; rdfs:label "hepatic peri-ductal inflammation"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_883 obo:IAO_0000115 "An interstitial, granulomatous, fibrosing inflammation of the lung, especially of the bronchioles and alveoli."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-09-04T11:18:21Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:883"^^xsd:string ; a owl:Class ; rdfs:label "pneumonitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_212 . obo:MPATH_884 obo:IAO_0000115 "Pneumonitis involving subpleural histiocytosis."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-09-04T11:19:22Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:884"^^xsd:string ; a owl:Class ; rdfs:label "histiocytic pneumonitis"^^xsd:string ; rdfs:subClassOf obo:MPATH_883 . obo:MPATH_885 obo:IAO_0000115 "metastatic tumour of unspecified origin"^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-09-04T11:28:57Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:885"^^xsd:string ; a owl:Class ; rdfs:label "metastatic tumor"^^xsd:string ; rdfs:subClassOf obo:MPATH_218 . obo:MPATH_886 obo:IAO_0000115 "Metastatic tumour of unspecified origin in the lung."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-09-04T11:30:02Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:886"^^xsd:string ; a owl:Class ; rdfs:label "pulmonary metastasis"^^xsd:string ; rdfs:subClassOf obo:MPATH_885 . obo:MPATH_887 obo:IAO_0000115 "Metastatic tumor in the lymphatic vessels or lymph nodes of unspecified origin."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-09-04T11:32:15Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:887"^^xsd:string ; a owl:Class ; rdfs:label "lymphatic metastasis"^^xsd:string ; rdfs:subClassOf obo:MPATH_885 . obo:MPATH_888 obo:IAO_0000115 "Hypertrophy of the nail bed resulting in abnormally long, curved and thickened nails."^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2012-09-04T12:10:49Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:888"^^xsd:string ; a owl:Class ; rdfs:label "onychogryphosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_631 . obo:MPATH_889 obo:IAO_0000115 " intracellular aggregates of actin and actin-associated proteins first observed in neurons (nerve cells) by Asao Hirano. PMID: 21978358"^^xsd:string ; oboInOwl:created_by "Paul"^^xsd:string ; oboInOwl:creation_date "2020-05-19T02:38:14Z"^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:889"^^xsd:string ; a owl:Class ; rdfs:label "Hirano body"^^xsd:string ; rdfs:subClassOf obo:MPATH_45 . obo:MPATH_89 obo:IAO_0000115 "Abnormal development of the heart or vascular tissue resulting in morphological abnormality."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:89"^^xsd:string ; a owl:Class ; rdfs:label "cardiovascular developmental defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_86 . obo:MPATH_9 obo:IAO_0000115 "Necrosis in which the necrotic tissue shows deeply eosinophilic staining similar to that of fibrin."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:9"^^xsd:string ; a owl:Class ; rdfs:comment "Frequently occurs in the walls of blood vessels and in connective tissue in diseases such as disseminated Lupus erythrematosis and polyarteritis nodosa, scleroderma, dermatomyositis and rheumatic fever."^^xsd:string ; rdfs:label "fibrinoid necrosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_4 . obo:MPATH_90 obo:IAO_0000115 "Localised dilation of an artery or heart chamber usually due to an acquired or congenital weakness of the wall of the artery or chamber."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:90"^^xsd:string ; a owl:Class ; rdfs:label "aneurysm"^^xsd:string ; rdfs:subClassOf obo:MPATH_56 . obo:MPATH_91 obo:IAO_0000115 "Formation of vessels between arterioles and venules bypassing capillary circulation."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Anastomosis arteriolovenularis"^^xsd:string, "anastomosis arteriovenosa"^^xsd:string, "arteriolovenular anastomosis"^^xsd:string ; oboInOwl:id "MPATH:91"^^xsd:string ; a owl:Class ; rdfs:label "arteriovenous anastomosis"^^xsd:string ; rdfs:subClassOf obo:MPATH_89 . obo:MPATH_92 obo:IAO_0000115 "Structural, organisational or growth related defects in cardiac development."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "heart abnormalities"^^xsd:string ; oboInOwl:id "MPATH:92"^^xsd:string ; a owl:Class ; rdfs:label "cardiac defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_89 . obo:MPATH_93 obo:IAO_0000115 "Abnormality in the wall between the atria or ventricles, or defects in the truncoconal septum, of the heart; usually incomplete closure."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:93"^^xsd:string ; a owl:Class ; rdfs:label "cardiac septation defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_92 . obo:MPATH_94 obo:IAO_0000115 "Malformation of the membranous folds of the heart that prevent reflux of fluid."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:94"^^xsd:string ; a owl:Class ; rdfs:label "valve defect"^^xsd:string ; rdfs:subClassOf obo:MPATH_92 . obo:MPATH_95 obo:IAO_0000115 "Thickening of the wall of one or both of the heart ventricles."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:95"^^xsd:string ; a owl:Class ; rdfs:label "hypertrophic ventricle"^^xsd:string ; rdfs:subClassOf obo:MPATH_92 . obo:MPATH_96 obo:IAO_0000115 "Reduction in cell number of one or both of the two lower chambers of the heart."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:96"^^xsd:string ; a owl:Class ; rdfs:label "hypoplastic ventricle"^^xsd:string ; rdfs:subClassOf obo:MPATH_92 . obo:MPATH_97 obo:IAO_0000115 "Follows the presence of a hematoma in the wall of an artery Splitting of the media occurs, blood enters the split through a tear in the intima."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:97"^^xsd:string ; a owl:Class ; rdfs:label "dissecting aneurysm"^^xsd:string ; rdfs:subClassOf obo:MPATH_90 . obo:MPATH_98 obo:IAO_0000115 "A stretching and widening of the lymphatic vessels."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasRelatedSynonym "Lymphectasia"^^xsd:string, "telangiectasia lymphatica"^^xsd:string ; oboInOwl:id "MPATH:98"^^xsd:string ; a owl:Class ; rdfs:label "lymphangiectasis"^^xsd:string ; rdfs:subClassOf obo:MPATH_474, obo:MPATH_89 . obo:MPATH_99 obo:IAO_0000115 "An enlarged and often tortuous vein."^^xsd:string ; oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "MPATH:99"^^xsd:string ; a owl:Class ; rdfs:label "varices"^^xsd:string ; rdfs:subClassOf obo:MPATH_56 . oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "is_a"^^xsd:string ; a owl:ObjectProperty ; rdfs:label "is a"^^xsd:string . oboInOwl:hasOBONamespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:id "part_of"^^xsd:string ; a owl:ObjectProperty, owl:TransitiveProperty ; rdfs:label "part of"^^xsd:string . oboInOwl:NamespaceIdRule "* MPATH:$sequence(3,0,999)$"^^xsd:string ; oboInOwl:auto-generated-by "OBO-Edit 2.3-beta5"^^xsd:string ; oboInOwl:default-namespace "mouse_pathology.ontology"^^xsd:string ; oboInOwl:hasOBOFormatVersion "1.2"^^xsd:string ; oboInOwl:saved-by "ORCID: 0000-0002-5111-7263"^^xsd:string ; a owl:Ontology ; rdfs:comment "The Pathbase mouse pathology ontology provides a description of experimental mouse pathology phenotypes and incorporates 889 concepts including anatomical pathological entities and pathological processes. These are organised in an almost entirely is_a hierarchy of pathological processes or anatomical entities. Questions, comments and suggestions for amendment should be sent to the Co-ordinator, Dr. Paul Schofield, Dept. of Physiology Development and Neuroscience, University of Cambridge (PNS12@cam.ac.uk).The ontology was developed by the Pathbase consortium (http://www.pathbase.net) funded under the European Commission's Fifth Framework programme, Contract number QLRI-CT-1999-00320."^^xsd:string ; owl:versionIRI . oboInOwl:NamespaceIdRule a owl:AnnotationProperty ; rdfs:label "namespace-id-rule"^^xsd:string . oboInOwl:auto-generated-by a owl:AnnotationProperty . oboInOwl:created_by a owl:AnnotationProperty . oboInOwl:creation_date a owl:AnnotationProperty . oboInOwl:default-namespace a owl:AnnotationProperty . oboInOwl:hasAlternativeId a owl:AnnotationProperty ; rdfs:label "has_alternative_id"^^xsd:string . oboInOwl:hasBroadSynonym a owl:AnnotationProperty ; rdfs:label "has_broad_synonym"^^xsd:string . oboInOwl:hasDbXref a owl:AnnotationProperty ; rdfs:label "database_cross_reference"^^xsd:string . oboInOwl:hasExactSynonym a owl:AnnotationProperty ; rdfs:label "has_exact_synonym"^^xsd:string . oboInOwl:hasOBOFormatVersion a owl:AnnotationProperty ; rdfs:label "has_obo_format_version"^^xsd:string . oboInOwl:hasOBONamespace a owl:AnnotationProperty ; rdfs:label "has_obo_namespace"^^xsd:string . oboInOwl:hasRelatedSynonym a owl:AnnotationProperty ; rdfs:label "has_related_synonym"^^xsd:string . oboInOwl:id a owl:AnnotationProperty . oboInOwl:saved-by a owl:AnnotationProperty . rdfs:comment a owl:AnnotationProperty . rdfs:label a owl:AnnotationProperty . owl:deprecated a owl:AnnotationProperty . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_0 ; owl:annotatedTarget "Pathological structure or process"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_104 ; owl:annotatedTarget "Defect in size, cellular composition, function or organisation of the spongiotrophoblast zone of the placenta."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_16 ; owl:annotatedTarget "myxomatosis"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_81 ; owl:annotatedTarget "Presence of a hole/channel through a normally imperforate structure often a membrane or septum."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_810 ; owl:annotatedTarget "Degenerative changes in hair follicles resulting in a deformed hair fiber, sometimes root sheath hyperplasia and follicular rupture."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_811 ; owl:annotatedTarget "Deposition of minerals in the epicardium."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_812 ; owl:annotatedTarget "A collection of fluid underneath the top layer of skin (epidermis)."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_813 ; owl:annotatedTarget "Lesions of a connective tissue disease causing blisters in the skin and mucosal membranes."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_814 ; owl:annotatedTarget "Locally circumscribed regions of fatty change."^^xsd:string . [] oboInOwl:hasDbXref "PMID: 21191096"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_815 ; owl:annotatedTarget "subtype of steatosis with Hepatocytes containing a large well-defined single rounded vacuole within each cell, nucleus and cytoplasm displaced to the periphery,"^^xsd:string . [] oboInOwl:hasDbXref "PMID:21191096"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_816 ; owl:annotatedTarget """Variant form of hepatic steatosis. Hepatocytes partially or completely filled with numerous small lipid vacuoles. Affected hepatocytes may have a foamy appearance.Small vacuoles do not normally displace the nucleus to the periphery in contrast to macrovesicular lipidosis."""^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_817 ; owl:annotatedTarget "Form of degenerative process in which there is Intracytoplasmic fluid accumulation secondary to disturbance of cell membrane integrity."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_82 ; owl:annotatedTarget "Persistence of an embryonic structure or tissue into the post-natal period in its normal location; (Chronological/temporal anomaly)."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_16 ; owl:annotatedTarget "A conversion of the connective tissues into a gelatinous or mucous substance."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_82 ; owl:annotatedTarget "Embryonic rest."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_820 ; owl:annotatedTarget "Increase in size of the thyroid gland caused initially by uniform follicular epithelial hyperplasia generally in response to iodine deficiency."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_821 ; owl:annotatedTarget "Tissue showing smaller mass as a consequence of deficient proliferation or premature differentiation."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_822 ; owl:annotatedTarget "Reduced mass of GALT resulting form fewer cells."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_823 ; owl:annotatedTarget "A benign neoplasm characterized by mucous and fibroblastic tissues."^^xsd:string . [] oboInOwl:hasDbXref "CUI:C1266121"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_824 ; owl:annotatedTarget "A benign localized neoplasm arising from the subcutaneous tissues and skeletal muscle. It is characterized by the presence of myofibroblastic hyperchromatic spindle cells, hylanized stroma formation, calcification, necrosis, and a multinodular growth pattern."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_825 ; owl:annotatedTarget "Generation of intracytoplasmic vacuoles otherwise unspecified."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_826 ; owl:annotatedTarget "granulomatous inflammation of the skin"^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_827 ; owl:annotatedTarget "chronic inflammation of the skin"^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_828 ; owl:annotatedTarget "locally demarcated region of inflammation in the skin"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_160 ; owl:annotatedTarget "Abnormal transformation of an fully differentiated adult cell or tissue of one kind into a differentiated tissue of another kind. An adult instance of developmental transdifferentiation MPATH:85 Traditionally defined as a form of abnormal regeneration in which a type of cell different from that found normally in a given location is produced."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_829 ; owl:annotatedTarget "possession of both ovary and testis due to primary sex determination defect"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_83 ; owl:annotatedTarget "Any defect in the formation of septae not describable as perforation."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_830 ; owl:annotatedTarget "repair, reproduction, or replacement of lost or injured cells, tissues, or organs."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_831 ; owl:annotatedTarget "multilocular sites of muscle regeneration with centrally located nuclei."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_832 ; owl:annotatedTarget "persistent retraction of the prepuce behind the glans penis"^^xsd:string . [] oboInOwl:hasDbXref "mpath:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_833 ; owl:annotatedTarget "transition between acute and chronic inflammation."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0-944398-45-6"^^xsd:string, "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_834 ; owl:annotatedTarget "non-malignant neoplasia of the ovary."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_835 ; owl:annotatedTarget "acute inflammation due to infection."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_836 ; owl:annotatedTarget "fibrosis in the skin"^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_837 ; owl:annotatedTarget "Fatty change in the mid-zonal region of the liver."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_161 ; owl:annotatedTarget "Metaplasia resulting in heterotopic formation of cartilage."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_838 ; owl:annotatedTarget "carcinoma with an absence of epithelial structural differentiation."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_839 ; owl:annotatedTarget "anaplastic carcinoma of the liver."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_84 ; owl:annotatedTarget "Additional structure whether normally located or not."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_840 ; owl:annotatedTarget "arthitis involving extensive macrophage infiltration into the joint."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_841 ; owl:annotatedTarget "Absence of eye."^^xsd:string . [] oboInOwl:hasDbXref "PMID:1666161"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_842 ; owl:annotatedTarget "abnormally shaped vertebral body often triangular as opposed to rectangular."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_843 ; owl:annotatedTarget "Cessation of movement of a body fluid or liquid."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_844 ; owl:annotatedTarget "Cessation of the flow of bile due to bile duct blockage or overproduction."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_845 ; owl:annotatedTarget "Evidence of residual placenta in utero without embryo."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_846 ; owl:annotatedTarget "acute inflammation of the footpad caused by foreign body."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_162 ; owl:annotatedTarget "Metaplasia occurring within epithelia."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_847 ; owl:annotatedTarget "Collection of epithelioid macrophages into a nodule"^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_848 ; owl:annotatedTarget "Replacement of normal tissue by granuloma."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_849 ; owl:annotatedTarget "poorly differentiated adenocarcinoma of the mammary gland"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_85 ; owl:annotatedTarget "Alteration in the differentiation of a cell or tissue already showing a different, recognisable, differentiated state."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_850 ; owl:annotatedTarget "Morphological abnormality following trauma or related insult such as infection."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_851 ; owl:annotatedTarget "acquired dysmorphology of the external pinna following trauma or infection."^^xsd:string . [] oboInOwl:hasDbXref "MPAHTH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_852 ; owl:annotatedTarget "A condition in which there is an unusually large proportion of plasma cells in tissues, exudates, or blood."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_853 ; owl:annotatedTarget "Abnormality of circulating plasma cells"^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_854 ; owl:annotatedTarget "Plasmacytosis in the skin."^^xsd:string . [] oboInOwl:hasDbXref "PMID:18976399"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_855 ; owl:annotatedTarget "In vivo formation of intensely eosinophilic material (radiate, star-like, asteroid or club-shaped configurations) around microorganisms (fungi, bacteria and parasites) or biologically inert substances."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_163 ; owl:annotatedTarget "Alteration of acinar epithelium of, for example, mammary tissue to resemble apocrine glands."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_856 ; owl:annotatedTarget "Rupture of alveolar walls result in large rounded open air spaces in the lung"^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_857 ; owl:annotatedTarget "mutilocular bullous emphysema"^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_858 ; owl:annotatedTarget "Benign proliferation of capillaries made up of closely packed aggregations of capillaries, usually of normal caliber, separated by scant connective stroma."^^xsd:string . [] oboInOwl:hasDbXref "ISBN: 0-7216-2921-0."^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_859 ; owl:annotatedTarget "Chronic granulomatous bacterial infection that affects the skin, and sometimes the viscera. Usually caused by S. aureus."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_86 ; owl:annotatedTarget "Developmental defect characteristic of a particular organ or organ system which may be a recognised syndrome or a complex defect showing multiple manifestations."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_860 ; owl:annotatedTarget "inflammation of the gall bladder"^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_861 ; owl:annotatedTarget "cholecystitis associated with edema"^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_862 ; owl:annotatedTarget "Accumulation or trapping of air"^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_863 ; owl:annotatedTarget "circumscribed ulceration of the skin penetrating the basement membrane as part of inflammation process."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_864 ; owl:annotatedTarget "Inflammation of the outer ear."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_164 ; owl:annotatedTarget "Appearance of heterotopic gastric epithelium."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curationf>"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_865 ; owl:annotatedTarget "Papillomatous inflammation of the tongue caused by a foreign body."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_866 ; owl:annotatedTarget "Thickening of the glandular epithelium"^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_867 ; owl:annotatedTarget "Major hepatic vein surrounded by fibrous connective tissue."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_868 ; owl:annotatedTarget "Dilation of the uterus"^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_869 ; owl:annotatedTarget "Condition in which a part of the intestine has invaginated into another section of intestine,"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_87 ; owl:annotatedTarget "Abnormal morphology, differentiation or location of primordial germ cells or their descendents. Not neoplastic."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_870 ; owl:annotatedTarget "severe type of the disorder generally apparent at birth.Junctional epidermolysis bullosa involves defects in hemidesmosomes. t"^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_871 ; owl:annotatedTarget "Structural defects of the bony and muscular components of the vertebrae."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_872 ; owl:annotatedTarget "Abnormality of the kyphotic curvature of the spine."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_873 ; owl:annotatedTarget "Reduced size of the eye globe."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_165 ; owl:annotatedTarget "Development of heterotopic glandular epithelia."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_874 ; owl:annotatedTarget "Plasmacytosis is a hyperplastic condition in which there is an unusually large proportion of mature plasma cells in tissues, exudates, or blood."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_875 ; owl:annotatedTarget "cutaneous manifestation of plasmacytosis"^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_876 ; owl:annotatedTarget "systemic manifestation of plasmacytosis. Disseminated in the circulation."^^xsd:string . [] oboInOwl:hasDbXref "http://en.wikipedia.org/wiki/Pneumonia"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_877 ; owl:annotatedTarget "An inflammatory condition of the lung, especially affecting the alveoli, associated with fever, chest symptoms, and congestion."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_878 ; owl:annotatedTarget "Pneumonia caused by aspiration of a foreign body."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_879 ; owl:annotatedTarget "Inflammation of the tooth gum"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_88 ; owl:annotatedTarget "nephroblastomatosis"^^xsd:string . [] oboInOwl:hasDbXref "MAPTH:"^^xsd:string, "MPATH:Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_880 ; owl:annotatedTarget "inflammation of the tooth gum caused by a foreign body."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_881 ; owl:annotatedTarget "Fibrotic reaction to presence of a foreign body."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:JPS"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_882 ; owl:annotatedTarget "Inflammatory cell infiltrate around bile ducts within the liver."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_166 ; owl:annotatedTarget "Metaplasia resulting in formation of mucus secreting goblet cells."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:JPS"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_883 ; owl:annotatedTarget "An interstitial, granulomatous, fibrosing inflammation of the lung, especially of the bronchioles and alveoli."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:JPS"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_884 ; owl:annotatedTarget "Pneumonitis involving subpleural histiocytosis."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_885 ; owl:annotatedTarget "metastatic tumour of unspecified origin"^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_886 ; owl:annotatedTarget "Metastatic tumour of unspecified origin in the lung."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_887 ; owl:annotatedTarget "Metastatic tumor in the lymphatic vessels or lymph nodes of unspecified origin."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:JPS"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_888 ; owl:annotatedTarget "Hypertrophy of the nail bed resulting in abnormally long, curved and thickened nails."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:PNS"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_889 ; owl:annotatedTarget " intracellular aggregates of actin and actin-associated proteins first observed in neurons (nerve cells) by Asao Hirano. PMID: 21978358"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_89 ; owl:annotatedTarget "Abnormal development of the heart or vascular tissue resulting in morphological abnormality."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_9 ; owl:annotatedTarget "Necrosis in which the necrotic tissue shows deeply eosinophilic staining similar to that of fibrin."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_90 ; owl:annotatedTarget "Localised dilation of an artery or heart chamber usually due to an acquired or congenital weakness of the wall of the artery or chamber."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_167 ; owl:annotatedTarget "Appearance of heterotopic intestinal epithelium."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_91 ; owl:annotatedTarget "Formation of vessels between arterioles and venules bypassing capillary circulation."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_91 ; owl:annotatedTarget "Anastomosis arteriolovenularis"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_91 ; owl:annotatedTarget "anastomosis arteriovenosa"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_91 ; owl:annotatedTarget "arteriolovenular anastomosis"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_92 ; owl:annotatedTarget "Structural, organisational or growth related defects in cardiac development."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_92 ; owl:annotatedTarget "heart abnormalities"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_93 ; owl:annotatedTarget "Abnormality in the wall between the atria or ventricles, or defects in the truncoconal septum, of the heart; usually incomplete closure."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_94 ; owl:annotatedTarget "Malformation of the membranous folds of the heart that prevent reflux of fluid."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_95 ; owl:annotatedTarget "Thickening of the wall of one or both of the heart ventricles."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_96 ; owl:annotatedTarget "Reduction in cell number of one or both of the two lower chambers of the heart."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_105 ; owl:annotatedTarget "Lesions leading to or consequent on failure of, or atypical movement of, blood throughout the body."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_168 ; owl:annotatedTarget "Metaplasia resulting in formation of fat cells."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_97 ; owl:annotatedTarget "Follows the presence of a hematoma in the wall of an artery Splitting of the media occurs, blood enters the split through a tear in the intima."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_98 ; owl:annotatedTarget "A stretching and widening of the lymphatic vessels."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_98 ; owl:annotatedTarget "Lymphectasia"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_98 ; owl:annotatedTarget "telangiectasia lymphatica"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_99 ; owl:annotatedTarget "An enlarged and often tortuous vein."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_169 ; owl:annotatedTarget ".A rare benign neoplasm of the mucosa of the urinary bladder or the urethra, consisting of tubular structures resembling those of the nephron."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_169 ; owl:annotatedTarget "nephrogenic adenoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_17 ; owl:annotatedTarget "Defect of a subcellular structure or organelle."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_170 ; owl:annotatedTarget "Appearance of oncocytic cells in for example an epithelium or tumor."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_171 ; owl:annotatedTarget "Change of a glandular or mucosal epithelium into squamous epithelium."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_172 ; owl:annotatedTarget "Metaplastic response of the transitional epithelium, for example in the bladder to give squamous metaplasia and glandular metaplasia for example."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_173 ; owl:annotatedTarget "A progressive disease of the bone marrow where neoplastic bone marrow stem cells lodge and grow at sites outside the bone marrow."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_174 ; owl:annotatedTarget "Metaplasia resulting in formation of bone."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_175 ; owl:annotatedTarget "The process, normal or abnormal, of damage repair or wound closure."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_106 ; owl:annotatedTarget "Abnormal accumulation of fluid; blood or lymph."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_176 ; owl:annotatedTarget "Replacement of connective tissue by fibro-fatty deposits and scar tissue."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_177 ; owl:annotatedTarget "Aberrant process of blood vessel formation and the subsequent remodeling process; does not refer to the initial establishment of the vascular network by vasculogenesis."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_178 ; owl:annotatedTarget "Abnormal deposition of extracellular matrix proteins or other components."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_179 ; owl:annotatedTarget "Deposition of fibrin."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_18 ; owl:annotatedTarget "Defect in the structure or function of the cytoskeleton."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_180 ; owl:annotatedTarget "Abnormal or reactive proliferation of fibroblasts."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_181 ; owl:annotatedTarget "Reactive formation of fibrous tissue."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_182 ; owl:annotatedTarget "Proliferation of astrocytes in an area of damage in the brain or spinal cord."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_183 ; owl:annotatedTarget "Newly formed connective (vascular or fibrous)tissue caused by inflammation or healing (repair) processes. Microscopically consists of capillaries fibroblastic cells and inflammatory cells."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_184 ; owl:annotatedTarget "Any pathological thickening or hardening of a tissue."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_107 ; owl:annotatedTarget "Presence of an abnormal amount of fluid (but especially of blood) in the vessels or passages of a part or organ."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_184 ; owl:annotatedTarget "Induration"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_185 ; owl:annotatedTarget "Post-injury regeneration of the functional tissue parenchyma. Eg. Liver."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_186 ; owl:annotatedTarget "Complete healing through parenchymal regeneration - no fibrosis."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_187 ; owl:annotatedTarget "Incomplete healing usually accompanied by fibrosis."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_188 ; owl:annotatedTarget "Inappropriate or aberrant activation or suppression of the immune or inflammatory response."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_189 ; owl:annotatedTarget "Immune response resulting in tissue injury."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_19 ; owl:annotatedTarget "Defect in the structure or function of the endoplasmic reticulum."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_190 ; owl:annotatedTarget "This is manifested by localized or generalized reaction that occurs immediately (minutes) after exposure to an antigen to which the person/animal was previously sensitized. It is IgE-mediated, and mast cell activation and degranulation are hallmarks."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_191 ; owl:annotatedTarget "Caused by an antibody/antigen reaction: antibodies are directly or indirectly cytotoxic to antigens on cell surfaces or in connective tissues."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_192 ; owl:annotatedTarget "Tissue injury mediated by immune complexes. Generally involves immune complexes formed in the blood via antibodies encountering circulating antigens. Immune complexes then deposit in tissues (especially blood vessels and glomeruli), induce complement activation, and result in tissue injury."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_108 ; owl:annotatedTarget "A syndrome consequent to uncontrolled activation of blood clotting factors leading to disseminated platelet lysis, and fibrin deposition, ultimately leading to bleeding and necrosis as a consequence of inhibition of fibrin polymerisation by degradation products."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_193 ; owl:annotatedTarget "An antigen-elicited cellular immune reaction that results in tissue damage, but does not require Ab participation. The response is seen at the area of contact."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_194 ; owl:annotatedTarget "Tissue response to inappropriate immune/inflammatory process."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_195 ; owl:annotatedTarget "Inflammation of a joint."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_196 ; owl:annotatedTarget "Inflammation of the skin."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_197 ; owl:annotatedTarget "Renal disease characterised by diffuse inflammatory changes in glomeruli not in response to an infectious agent or treatment."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_198 ; owl:annotatedTarget "An anemic/erythrocytopenic condition resulting from an increased rate of immune mediated erythrocyte destruction."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_199 ; owl:annotatedTarget "A condition resulting from an increased rate of immune mediated platelet destruction."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_2 ; owl:annotatedTarget "Complete and irreversible cessation of metabolic activity."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_20 ; owl:annotatedTarget "Defect in the structure or function of the golgi apparatus."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_200 ; owl:annotatedTarget "Inflammation of a muscle."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_108 ; owl:annotatedTarget "DIC"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_200 ; owl:annotatedTarget "Initis"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_201 ; owl:annotatedTarget "Inflammation of a blood vessel."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_201 ; owl:annotatedTarget "angiitis"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_201 ; owl:annotatedTarget "arteritis"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_201 ; owl:annotatedTarget "lymphangiitis"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_201 ; owl:annotatedTarget "phlebitis"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_202 ; owl:annotatedTarget "Defective immune response; can be primary due to defect in immune system or secondary/acquired due to disease."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_203 ; owl:annotatedTarget "general immunodeficiency disease"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_204 ; owl:annotatedTarget "chronic/recurrent inflammatory disease"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_205 ; owl:annotatedTarget "Infection with bacteria, viruses or fungi subsequent to immunodeficiency."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_109 ; owl:annotatedTarget "An accumulation of an excessive amount of watery fluid in cells or intercellular tissues."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_206 ; owl:annotatedTarget "Disease due to primary molecular or cellular defect in the immune system or its development."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_207 ; owl:annotatedTarget "Primary defect in the lymphoid arm of the immune system."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_208 ; owl:annotatedTarget "Primary defect in the myeloid arm of the immune system."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_209 ; owl:annotatedTarget "Defect in the immune system subsequent to external injury, infection, ablation or deficiency."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_21 ; owl:annotatedTarget "Defect in the structure or function of the lysosomes."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_210 ; owl:annotatedTarget "Defect in the immune system subsequent to external injury, infection or ablation."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_211 ; owl:annotatedTarget "Defect in the immune system subsequent to failure to attain passive immunity from maternal transfer of immunoglobulins."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_212 ; owl:annotatedTarget "A tissue reaction to an internal or external injury."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_213 ; owl:annotatedTarget "Inflammation with a recent onset, characterised histologically by primarily granulocyte infiltration, edema and hyperemia."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_214 ; owl:annotatedTarget "Chronic inflammatory condition characterised by infiltration of primarily lymphocytes."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_11 ; owl:annotatedTarget "Necrosis associated with local hemorrhage."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_215 ; owl:annotatedTarget "Nodular inflammatory reaction, containing compactly grouped epithelioid cells, giant cells, and other macrophages. The basic inflammatory unit is termed a granuloma."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_216 ; owl:annotatedTarget "Acute inflammatory reaction in which the predominant histological change is rapid diffuse necrosis throughout the affected tissue."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_217 ; owl:annotatedTarget "Combination of inflammation, often suppurative or granulomatous, with ulceration."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_218 ; owl:annotatedTarget "A tumor resulting from abnormal and uncontrolled autonomous new cell growth (proliferation)that may be benign or malignant."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_219 ; owl:annotatedTarget "Tumors of the skin, its constituent structures and glands including the mammary gland, apocrine and eccrine glands, hair follicles and associated structures."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_22 ; owl:annotatedTarget "Defect in the structure or function of the mitochondria."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_220 ; owl:annotatedTarget "Carcinoma of the glandular epithelium of apocrine glands (M-8401/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_221 ; owl:annotatedTarget "Benign neoplasm of the epithelium of apocrine glands (M-8401/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_222 ; owl:annotatedTarget "Malignant carcinoma of the ceruminous gland (M-8420/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_223 ; owl:annotatedTarget "Benign adenomatous neoplasia of the ceruminous glands of the external auditory meatus (M-8420/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_110 ; owl:annotatedTarget "A plug formed from a variety of materials occluding a vessel or tube."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_224 ; owl:annotatedTarget "Tumor derived from eccrine sweat glands composed of clear glycogen rich cells. ( M-84020 )."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_224 ; owl:annotatedTarget "Eccrine acrospiroma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_224 ; owl:annotatedTarget "nodular hidradenoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_225 ; owl:annotatedTarget "Malignant neoplasm of the eccrine gland (M-8413/3)."^^xsd:string . [] oboInOwl:hasDbXref ":Papillary adenoma"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_226 ; owl:annotatedTarget "Benign neoplasm of the eccrine gland (M-8408/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_227 ; owl:annotatedTarget "Papillary form of eccrine sweat gland adenoma. (M -8408/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_227 ; owl:annotatedTarget "Papillary adenoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_227 ; owl:annotatedTarget "benign neoplasm of the eccrine gland, papillary form"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_228 ; owl:annotatedTarget "Benign apocrine sweat gland tumor (8405/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_228 ; owl:annotatedTarget "Hidradenoma papilliferum"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_111 ; owl:annotatedTarget "An bubble of air occluding flow through a blood or lymphatic vessel."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_229 ; owl:annotatedTarget "Malignant neoplasm of the sebaceous cells - rare areas of differentiation, severe nuclear atypia (M-8410/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_229 ; owl:annotatedTarget "sebaceous carcinoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_23 ; owl:annotatedTarget "Defect in the structure or function of the peroxysomes."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_230 ; owl:annotatedTarget "Adenoma of sebaceous cells; regular architecture of gland not mantained. Large numbers of immature germinative cells present. Mitoses. (M-8410/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_230 ; owl:annotatedTarget "Epithelioma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_231 ; owl:annotatedTarget "A benign, often multiple, sometimes eruptive neoplasm of the sweat gland ducts composed of very small round cysts. (M-8407/0)."^^xsd:string . [] oboInOwl:hasDbXref "URL:http://emice.nci.nih.gov/emice/mouse_models/organ_models/skin_models"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_232 ; owl:annotatedTarget "Multiple small benign nodules derived from basal cells of hair follicles enclosing small cornified cell containing cysts. (M-8100/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_232 ; owl:annotatedTarget "Epithelioma adenoides cysticum"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_232 ; owl:annotatedTarget "benign"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_232 ; owl:annotatedTarget "hair follicle tumor"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_1 ; owl:annotatedTarget "The sum of morphological and functional disturbances induced by cell and tissue damage, either from intrinsic gene dysfunction or as a result of external factors."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_112 ; owl:annotatedTarget "Occlusion of vessels caused by entry of amniotic fluid, cell and debris into the maternal circulation."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_233 ; owl:annotatedTarget "Well circumscribed tumor of the basal cells of the epidermis. Rare mitotic figures, benign. (M8147/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_233 ; owl:annotatedTarget "Benign basal cell tumor"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_233 ; owl:annotatedTarget "basal cell adenoma"^^xsd:string . [] oboInOwl:hasDbXref "URL:http://emice.nci.nih.gov/emice/mouse_models/organ_models/skin_models"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_234 ; owl:annotatedTarget "Malignant neoplasm of the basal cells of the epidermis with local invasion. (M-8090/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_235 ; owl:annotatedTarget "Tumor of venous or arterial vessels or capillaries."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_236 ; owl:annotatedTarget ".A benign neoplasm of fibrous tissue in which there are multiple large and small dilated vascular channels ( M9160/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_236 ; owl:annotatedTarget "Telangiectatic fibroma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_237 ; owl:annotatedTarget "An intradermal capillary telangiectasis with hyperkeratosis and acanthosis (M-9141/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_237 ; owl:annotatedTarget "keratoangioma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_237 ; owl:annotatedTarget "telangiectasia verrucosa"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_113 ; owl:annotatedTarget "Occlusion of the outflow tract of the right atrium by a thrombus."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_237 ; owl:annotatedTarget "telangiectatic wart"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_238 ; owl:annotatedTarget "A benign neoplasm frequently arising in the cerebellum composed of capillary vessel forming endothelial cells and stromal cells. (M-9161/1)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_238 ; owl:annotatedTarget "Angioblastoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_239 ; owl:annotatedTarget "hemangioendothelioma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_24 ; owl:annotatedTarget "Defect in the structure or function of the plasma membrane."^^xsd:string . [] oboInOwl:hasDbXref "PMID:8569146"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_240 ; owl:annotatedTarget "Neoplasm derived from endothelial cells. May be of capillary or cavernous type with large vascular channels. (M-9130/0 + M-9120/0 respectively)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_240 ; owl:annotatedTarget "Angioendothelioma."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_240 ; owl:annotatedTarget "Hemangioendothelioma, benign"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_241 ; owl:annotatedTarget "A vascular, usually benign, neoplasm composed of round and spindle cells derived from the pericytes and surround endothelium-lined vessels. (M-9150/0/1/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_241 ; owl:annotatedTarget "Pericytoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_114 ; owl:annotatedTarget "Occlusion of vessels caused by entry of bone marrow, often fatty debris into the circulation. Usually following trauma."^^xsd:string . [] oboInOwl:hasDbXref "PMID:8569146"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_242 ; owl:annotatedTarget "Malignant neoplasm derived from pluripotential mesenchymal stem cells or endothelial cells of blood vessels. (M-9120/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_242 ; owl:annotatedTarget "Hemangioma malignant"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_242 ; owl:annotatedTarget "hemangioendothelioma malignant, angiosarcoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_242 ; owl:annotatedTarget "hemangioendothelioma malignant."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_243 ; owl:annotatedTarget "Neoplasm of the neurones, glia or meninges of the CNS."^^xsd:string . [] oboInOwl:hasDbXref "ISBN-13:9783794515530"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_244 ; owl:annotatedTarget "Glioma derived from astrocytes, both benign and malignant forms (M-9400/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_244 ; owl:annotatedTarget "Astrocytic glioma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_244 ; owl:annotatedTarget "astroglioma"^^xsd:string . [] oboInOwl:hasDbXref "ISBN-13:9783794515530"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_245 ; owl:annotatedTarget "Malignant neoplasm derived from the epithelial cells of the choroid plexus. (M-9390/3)."^^xsd:string . [] oboInOwl:hasDbXref "ISBN-13:9783794515530"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_246 ; owl:annotatedTarget "Benign neoplasm derived from the epithelial cells of the choroid plexus. (M-9390/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_115 ; owl:annotatedTarget "Occlusion of vessels caused by entry of lipid or fatty cells into the circulation. Usually following trauma."^^xsd:string . [] oboInOwl:hasDbXref "ISBN-13:9783794515530"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_247 ; owl:annotatedTarget "Neoplasm derived from the ependymal cells lining the ventricles and aqueduct of the brain and the central canal of the spinal cord. Malignant or benign. (M-9391/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_248 ; owl:annotatedTarget "ependymoma malignant"^^xsd:string . [] oboInOwl:hasDbXref "ISBN-13:9783794515530"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_249 ; owl:annotatedTarget "Neoplasm derived from astrocytes and oligodendrocytes. (M-9380/3, M-9440/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_25 ; owl:annotatedTarget "Degenerative process characteristic of a particular tissue."^^xsd:string . [] oboInOwl:hasDbXref "ISBN-13:9783794515530"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_250 ; owl:annotatedTarget "Neoplasm derived from the primitive neurectodermal cells of the cerebellum. (M-9470/3). May be considered by some authorities a synonym of PNET in the CNS."^^xsd:string . [] oboInOwl:hasDbXref "ISBN-13:9783794515530"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_251 ; owl:annotatedTarget "meningioma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_251 ; owl:annotatedTarget "Sarcoma, meningeal ( sensu malignant tumor)"^^xsd:string . [] oboInOwl:hasDbXref "ISBN-13:9783794515530"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_252 ; owl:annotatedTarget "Benign or malignant neoplasm derived form oligodendrocytes (M-9450/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_252 ; owl:annotatedTarget "Glioma, oligodendritic, benign"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_252 ; owl:annotatedTarget "glioma oligodendritic, malignant"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_116 ; owl:annotatedTarget "Occlusion of pulmonary vessels by an embolus."^^xsd:string . [] oboInOwl:hasDbXref "ISBN-13:9783794515530"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_253 ; owl:annotatedTarget "Neoplasm derived from sub-ependymal astrocytes (M-9383/1)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_254 ; owl:annotatedTarget "Tumors showing multiple histological componants/differentiation."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_255 ; owl:annotatedTarget "Mixed tumor of glandular epithelia with squamous and glandular diffferentiation. (M-8570/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_255 ; owl:annotatedTarget "adenoid squamous cell carcinoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_256 ; owl:annotatedTarget "Possible origin from smooth muscle cells or pluripotential embryonic mesenchymal cells. May show up to three cellular componants including carcinoma and sarcoma type appearances. (M-8980/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_257 ; owl:annotatedTarget "A benign or malignant neoplasm, which may be cystic, developing from the epithelium of Rathke`s pouch and occuring with or close to the pituitary gland. (M-9350/1)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_257 ; owl:annotatedTarget "Erdheim tumor"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_257 ; owl:annotatedTarget "Pituitary adamantinoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_257 ; owl:annotatedTarget "Rathke pouch tumor"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_257 ; owl:annotatedTarget "pituitary ameloblastoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_117 ; owl:annotatedTarget "Occlusion of vessels, usually small arterioles in the dermis by various emboli."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_257 ; owl:annotatedTarget "suprasellar cyst"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_258 ; owl:annotatedTarget "Neoplasm showing multiple phases, derived from mesoderm (M-8951/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_259 ; owl:annotatedTarget "Most commonly a salivary gland carcinoma of low grade malignancy composed of mucous, epidermoid, and intermediate cells. (M-8430/3)."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_26 ; owl:annotatedTarget "Absence of hair or loss of hair."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_260 ; owl:annotatedTarget "Neoplasm usually of the uterus or adnexae containing carcinomatous and sarcomatous elements, sometimes with third or fourth components. (M-8950/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_261 ; owl:annotatedTarget "Embryonal tumor thought to be derived from metanephric blastema. Mono, bi or triphasic, sometimes with heterotypic differentiation. (M-8960/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_261 ; owl:annotatedTarget "nephroma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_262 ; owl:annotatedTarget "A biphasic tumor containing a primitive epithelial component, that may resemble well-differentiated fetal adenocarcinoma and a primitive mesenchymal stroma, which occasionally has foci of osteosarcoma, chondrosarcoma or rhadomyosarcoma. (M-8972/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_263 ; owl:annotatedTarget "Sarcomatous tumors, presenting a wide histological, ultrastructural, and immunocytochemical spectrum. M-8963/3."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_263 ; owl:annotatedTarget "Malignant rhabdoid tumor"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_118 ; owl:annotatedTarget "Production of systemic vessel occlusion by emboli released from the left side of the heart, or the aorta."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_264 ; owl:annotatedTarget "Tumors with epithelial invaginations/linings and a fibrillary and fibrocytic stroma. (M-9000 - M-9030)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_265 ; owl:annotatedTarget "A benign neoplasm composed of glandular and fibrous tissues, predominantly glandular. (M-9013/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_265 ; owl:annotatedTarget "Cystadenofibroma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_265 ; owl:annotatedTarget "papillary adenofibroma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_266 ; owl:annotatedTarget "A benign neoplasm derived from glandular epithelium, in which there is a abundant stroma of proliferating fibroblasts and connective tissue. (M-9010/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_267 ; owl:annotatedTarget "Neoplasms derived from glandular epithelial cells."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_268 ; owl:annotatedTarget "Malignant neoplasm of epithelial cells in glandular or glandlike pattern. (M-8140/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_269 ; owl:annotatedTarget "A noninvasive abnormal proliferation of glands believed to precede the appearance of invasive adenocarcinoma. (M-8140/2)."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_27 ; owl:annotatedTarget "Changes characterized by erosion of articular cartilage, either primary or secondary to trauma or other conditions. Not primarily an inflammatory process."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_27 ; owl:annotatedTarget "Degenerative joint disease"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_119 ; owl:annotatedTarget "Abnormal release of whole blood or the cellular component from the circulation."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_27 ; owl:annotatedTarget "osteoarthrosis"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_270 ; owl:annotatedTarget "A benign epithelial neoplasm in which the tumor cells may form glands or glandlike structures. In different instances this may remain a benign tumor or progress to malignancy."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_271 ; owl:annotatedTarget "Spontaneous intestinal adenoma formation. Polyps increase in number, causing symptoms of chronic colitis and potentially transform into adenocarcinoma. (M-8220/0)."^^xsd:string . [] oboInOwl:hasDbXref "PMID:15059877"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_272 ; owl:annotatedTarget "Benign epithelial neoplasm of the lung. (M-8140/1) 1.2.1.2 in MMHCC classification."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_272 ; owl:annotatedTarget "Bronchial adenoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_272 ; owl:annotatedTarget "Bronchial adenoma, BA adenoma"^^xsd:string . [] oboInOwl:hasDbXref "PMID:15059877"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_273 ; owl:annotatedTarget "Malignant epithelial neoplasm of the lung. (M-8250/3) 1.2.3.2, 1.2.3.5 of MMHCC classification."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_273 ; owl:annotatedTarget "Bronchioloalveolar adenocarcinoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_273 ; owl:annotatedTarget "Bronchioloalveolar adenocarcinoma, bronchioalveolar carcinoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_274 ; owl:annotatedTarget "An adenocarcinoma characterised by the presence of varying combinations of clear and hobnail-shaped tumor cells. (M-8310/3)."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_12 ; owl:annotatedTarget "Soft or fluid tissue remains of a circumscribed area of necrosis digested by proteolytic enzymes."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_275 ; owl:annotatedTarget "Form of carcinoma of the breast or other organ in which plugs of necrotic malignant cells are present in the ducts. (M -8501/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_276 ; owl:annotatedTarget "Malignant neoplasm derived from glandular epithelium, in which cystic accumulations of retained secretions are formed. (M-8440/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_277 ; owl:annotatedTarget "A benign neoplasm derived from glandular epithelium, in which cystic accumulations of retained secretions are formed. (M-8440/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_278 ; owl:annotatedTarget "Originates in the follicular cells of thyroid follicles. Papillary, solid and follicular forms. (M- 8330/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_278 ; owl:annotatedTarget "Follicular carcinoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_279 ; owl:annotatedTarget "Adenoma derived from the follicular cells of the thyroid follicles. Follicular, paipillary and solid forms. M- 8330/0."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_28 ; owl:annotatedTarget "Characterised by irregular lipid deposits in the wall of arteries, causing narrowing of their lumens and proceeding eventually to fibrosis and calcification."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_280 ; owl:annotatedTarget "Adenoma derived from acinar epithelium of the harderian gland. Papillary, cystic, cystic-papillary and acinar forms."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_281 ; owl:annotatedTarget "Malignant tumor derived form acinar epithelium of the Harderian gland."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_282 ; owl:annotatedTarget "Derived from the mammary ductal epithelium and penetrating the stroma (M-8500/3)."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_120 ; owl:annotatedTarget "A red/purple patch caused by extravasation of blood into the skin. Larger than petechiae."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_282 ; owl:annotatedTarget "Infiltrating ductal adenocarcinoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_282 ; owl:annotatedTarget "duct adenocarcinoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_282 ; owl:annotatedTarget "ductal carcinoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_283 ; owl:annotatedTarget "In situ carcinoma of the mammary ductal epithelium. (M- 8500/2)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_283 ; owl:annotatedTarget "Ductal carcinoma in situ"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_283 ; owl:annotatedTarget "intraductal adenocarcinoma, non-infiltrating"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_284 ; owl:annotatedTarget "Infiltrating tumor with papillary morphology derived from the breast epithelium (M-8503/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_284 ; owl:annotatedTarget "Intraductal papillary adenocarcinoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_285 ; owl:annotatedTarget "Benign papilloma arising from ductal epithelium (M- 8503/0 )."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_10 ; owl:annotatedTarget "Extensive necrosis from whatever cause, often following chronic ischemia."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_121 ; owl:annotatedTarget "A localised deposition of clotted or partially clotted extravasated blood."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_285 ; owl:annotatedTarget "Duct adenoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_285 ; owl:annotatedTarget "ductal papilloma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_286 ; owl:annotatedTarget "Diffuse multiple adenomatous papillomas derived from the ductal epithelium of the breast. (M- 8505/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_286 ; owl:annotatedTarget "Diffuse intraductal papillomatosis"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_287 ; owl:annotatedTarget "Usually pancreatic B cell derived tumors mostly producing insulin. (M- 8150/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_287 ; owl:annotatedTarget "Adenoma, endocrine pancreas"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_287 ; owl:annotatedTarget "adenomatosis"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_287 ; owl:annotatedTarget "islet (pancreatic) cell tumor benign"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_288 ; owl:annotatedTarget "Rare tumor of the islets of Langerhans, most of which produce insulin. (M- 8150/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_288 ; owl:annotatedTarget "Adenocarcinoma, endocrine pancreas"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_121 ; owl:annotatedTarget "Bruise"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_288 ; owl:annotatedTarget "islet cell tumor, malignant"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_289 ; owl:annotatedTarget "A form of breast adenocarcinoma derived from lobular cells. (M-8520/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_289 ; owl:annotatedTarget "Lobular adenocarcinoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_289 ; owl:annotatedTarget "lobular infiltrating carcinoma"^^xsd:string . [] oboInOwl:hasDbXref "PMID:9309781"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_29 ; owl:annotatedTarget "Opacity of the lens."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_290 ; owl:annotatedTarget "Non-infiltrating form of lobular adenocarcinoma derived from the ductal epithelium. (M-8520/2)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_290 ; owl:annotatedTarget "mammary intra-epithelial neoplasia"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_291 ; owl:annotatedTarget "Derived from calcitonin-producing cells (thyroid). In humans a type of carcinoma composed of epithelial elements with considerable lymphoid stroma (breast). Not yet reported in mice. (M-8510/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_291 ; owl:annotatedTarget "Medullary adenocarcinoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_292 ; owl:annotatedTarget "Malignant neoplasm derived from a glandular epithelium, eg. Ovary. Consisting of a solid to cystic mass lined with cuboidal pleomorphic epithelial cells producing a mucinous material. (M- 8470/3)."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_122 ; owl:annotatedTarget "Small hemorrhagic spots in the skin caused by blood vessel breakdown."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_293 ; owl:annotatedTarget "A benign neoplasm derived from glandular epithelium, in which cystic accumulations of mucinous retained secretions are formed. (M-8470/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_294 ; owl:annotatedTarget "Tumor originating in myoepithelial cells of exocrine glandular structures; for example mammary gland, salivary gland and preputial/clitoral glands. (M-8982/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_294 ; owl:annotatedTarget "myoepithelial adenoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_295 ; owl:annotatedTarget "A malignant neoplasm derived from a glandular epithelium, in which solid tumors show papillary structures projecting onto fibrovascular stroma. (M-8260/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_296 ; owl:annotatedTarget "A benign neoplasm derived from a glandular epithelium, in which solid tumors show papillary structures projecting onto fibrovascular stroma. (M-8260/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_297 ; owl:annotatedTarget "A malignant neoplasm derived from glandular epithelium, in which cysts contain folds or papillary projections into the lumen. (M-8450/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_298 ; owl:annotatedTarget "A benign neoplasm derived from glandular epithelium, in which cysts contain folds or papillary projections into the lumen. (M-8450/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_299 ; owl:annotatedTarget "Originating from differentiated cells of the pineal parenchyma. Not to be confused with human pinealoma (syn: germinoma) non-gonadal germ cell tumors found in the pineal believed to be atypical teratomas. May be benign or malignant. If ectopic teratomas/teratocarcinomas use MP322 or MP321. (M-9360/1)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_3 ; owl:annotatedTarget "Energy dependent cell death induced by intrinsic genetic or developmental programme, or external stimuli such as addition or withdrawal of cytokines or trophic factors, radiation, chemotherapeutic agents etc. Characterised by cell shrinkage, increases in membrane permeability, endonucleolyis and nuclear fragmentation resulting in the formation of rapidly endocytosed apoptotic bodies."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_3 ; owl:annotatedTarget "programmed cell death"^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_123 ; owl:annotatedTarget "Purple and variously colored lesions caused by extensive haemorrhage into the skin through ecchymoses/petechia."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_30 ; owl:annotatedTarget "Loss of muscle fibers and elastin in the media of the aorta, with accumulation of mucopolysaccharide."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_30 ; owl:annotatedTarget "Erdheim disease"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_30 ; owl:annotatedTarget "Mucoid medial degeneration"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_30 ; owl:annotatedTarget "media necrosis aortae idiopathica cystica"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_30 ; owl:annotatedTarget "media necrosis of the aorta"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_300 ; owl:annotatedTarget "Malignant neoplasms which arise from pineoblasts, the primitive pineal stem cells. (M-9362/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_300 ; owl:annotatedTarget "Mixed pineal tumor"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_300 ; owl:annotatedTarget "pineal parenchymal tumor of intermediate differentiation"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_300 ; owl:annotatedTarget "transitional pineal tumor"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_301 ; owl:annotatedTarget "A tumor arising in the pineal gland that resembles normal pineal parenchyma. (M-9361/1)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_124 ; owl:annotatedTarget "An area of necrosis resulting from a sudden cessation of arterial or venous blood supply."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_302 ; owl:annotatedTarget "Benign tumor derived from the pituicytes ( glial cells of neurohypophysis) (M-8272/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_302 ; owl:annotatedTarget "pituitary adenoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_303 ; owl:annotatedTarget "Tumor characterized by extensive spread of a mucin-secreting neoplasm along the peritoneal surfaces (M-8480/6)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_304 ; owl:annotatedTarget "Adenocarcinoma from a serous gland producing and containing serous proteinaceous secretions (M-8441/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_305 ; owl:annotatedTarget "Ovarian cystadenoma composed of cells similar to tubal epithelium (M-8441/0)."^^xsd:string . [] oboInOwl:hasDbXref "PMID:12612914"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_306 ; owl:annotatedTarget "Adenocarcinoma of signet ring type arising from exocrine cells of the gastric mucosa or enterocytes of intestinal mucosa. (M-8490/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_306 ; owl:annotatedTarget "Signet ring cell adenocarcinoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_306 ; owl:annotatedTarget "signet ring cell carcinoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_307 ; owl:annotatedTarget "Benign neoplasm derived from the calcitonin producing C-cells of the thyroid gland."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_307 ; owl:annotatedTarget "Adenoma, parafollicular cell"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_125 ; owl:annotatedTarget "Presence of an occluding or mural thrombus in a blood vessel."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_307 ; owl:annotatedTarget "tumor c-cell benign"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_308 ; owl:annotatedTarget "Malignant neoplasm derived from the calcitonin producing C-cells of the thyroid gland. (M-8510/3, M-8345/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_308 ; owl:annotatedTarget "Medullary carcinoma, parafollicular cell"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_308 ; owl:annotatedTarget "tumor c-cell malignant"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_309 ; owl:annotatedTarget "Germ cell and non-germ cell tumors of the testis and ovary."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_31 ; owl:annotatedTarget "Abnormal accumulation of air in the interstitial connective tissue of a structure. Sensu Lung: Pulmonary emphysema; characterised by abnormal increase in the size of air (alveolar) spaces distal to the terminal bronchiole with degenerative changes in their walls and reduction in their number."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_310 ; owl:annotatedTarget "Neoplasms derived from germ cells. May be gonadal or extragonadal and are derived from primordial germ cells."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_311 ; owl:annotatedTarget "Cystic ovarian teratomas with different mature cell types (M-9084/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_312 ; owl:annotatedTarget "Undifferentiated germ cell tumor of the ovary composed of solid sheets of large polygonal cells with rim of clear cytoplasm (M-9060/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_312 ; owl:annotatedTarget "Seminoma (sensu male)"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_126 ; owl:annotatedTarget "Defects in growth (changes in proliferation or mass) and differentiation of cells tissues or organs."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_313 ; owl:annotatedTarget "Germ cell derived malignant neoplasm of the testis or ovary, composed of anaplastic cells with indistinct cellular borders and large ovoid, round, or bean-shaped nuclei that may have large nucleoli. (M-9070/3 )."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_314 ; owl:annotatedTarget "Germ cell derived tumors resembling parietal or visceral yolk sac endoderm derivatives. Abundant eosinophilic matrix surrounding nests and cords of neoplastic cells. (M-9071-3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_314 ; owl:annotatedTarget "Yolk sac carcinoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_315 ; owl:annotatedTarget "Gonadal neoplasms that consist of aggregates of germ cells and sex cord elements (M-9073/1)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_315 ; owl:annotatedTarget "Gonocytoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_316 ; owl:annotatedTarget "Malignant neoplasm of the testis/ovary including various elements of germ cell tumors (M-9085/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_316 ; owl:annotatedTarget "Mixed teratoma and seminoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_317 ; owl:annotatedTarget "Tumor derived from spermatogenic cells resembling spermatogenia or spermatocytes. NOS ( M9061/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_317 ; owl:annotatedTarget "Germinoma, malignant"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_317 ; owl:annotatedTarget "dysgerminoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_127 ; owl:annotatedTarget "A reduction in size of organs or tissues as a result of cell death, loss of cellularity of whatever cause, reduced cellular proliferation or decreased cellular volume."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_317 ; owl:annotatedTarget "spermatoblastoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_317 ; owl:annotatedTarget "spermatocytoma, malignant."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_318 ; owl:annotatedTarget "As MPATH:317, but not spermatocytic (M-9061/3)."^^xsd:string . [] oboInOwl:hasDbXref ":Walt; H.; Oosterhuis; J.W. and Stevens; L.C. (1993) Int J Androl; 16; 267-271"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_319 ; owl:annotatedTarget "Neoplasm of the testis usually found within the tubule. Some debate as to whether it is of germ cell origin in contrast to classical seminoma. Three types of cells are identified in spermatocytic seminomas: those with small, intermediate, and large nuclei in humans. (M-9063/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_319 ; owl:annotatedTarget "Spermatoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_32 ; owl:annotatedTarget "Increase in the intraocular pressure."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_320 ; owl:annotatedTarget "Rare ovarian tumor, regarded as monodermal teratoma, in which thyroid tissue has surpassed the other elements; occasionally associated with hyperthyroidism (M-9090/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_321 ; owl:annotatedTarget "Mixed germ cell neoplasm contaning elements of embryonal carcinoma and teratoma (M-9081/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_322 ; owl:annotatedTarget "Generally benign germ cell derived tumors of male or female containing derivatives from all three germ layers with differentiation in the malignant form being poor. Malignant tumors are highly metatstatic. (M-9080/1)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_323 ; owl:annotatedTarget "Neoplasms derived from the non-germ cell derived tissues of the testis and ovary."^^xsd:string . [] oboInOwl:hasDbXref "Journal: Ward; J.M. ( 2002) J Toxicol. Pathol. 15; 123-128"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_128 ; owl:annotatedTarget "Non-invasive changes characterized by alteration in the size, shape and organization of the cellular components of an epithelial tissue. Do not confuse with developmental dysplasia MPATH:64."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_324 ; owl:annotatedTarget "obsolete use Sertoli cell tumor MPATH: 331."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_325 ; owl:annotatedTarget "obsolete use thecoma MPATH:334."^^xsd:string . [] oboInOwl:hasDbXref "PMID:9789961"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_326 ; owl:annotatedTarget ". Derived from sex cord stromal cells. In male thought to be Sertoli cells. (M- 8620/1)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_326 ; owl:annotatedTarget "Tumor, sex cord stromal, benign, granulosa cell type"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_326 ; owl:annotatedTarget "gynoblastoma (sensu malignant form in ovary)"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_327 ; owl:annotatedTarget "gynandroblastoma"^^xsd:string . [] oboInOwl:hasDbXref "Mahler M; Sundberg JP ( 1997) Spontaneous Leydig cell tumors in inbred laboratory mice Lab Animal Science 47:148-52"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_328 ; owl:annotatedTarget "Tumor derived from Leydig cells (M-8650/1)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_328 ; owl:annotatedTarget "Interstitial cell tumor, benign"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_328 ; owl:annotatedTarget "Leydig cell adenoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_329 ; owl:annotatedTarget "Tumor derived from sex cords composed of highly luteinised cells with extensive pale granular cytoplasm. (M- 8610/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_128 ; owl:annotatedTarget "intra-epithelial lesion"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_329 ; owl:annotatedTarget "Luteoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_329 ; owl:annotatedTarget "luteinised granulosa cell tumor, benign. Gonadal sex cord stromal tumor, benign, luteoma type"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_33 ; owl:annotatedTarget "Accumulation of substances within, on the surface of or between cells."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_330 ; owl:annotatedTarget "Tumor consists of a mixture of granulosa, luteal thecal, Sertoli and stromal cells. (M-8590/1)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_331 ; owl:annotatedTarget "Tumor derived from sex cord/stromal cells; Sertoli cells and can occur in both testis and ovary. (M-8640/1)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_331 ; owl:annotatedTarget "Androblastoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_331 ; owl:annotatedTarget "arrhenoblastoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_331 ; owl:annotatedTarget "gonadal stromal tumor"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_331 ; owl:annotatedTarget "sex cord stromal tumor"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_331 ; owl:annotatedTarget "sustentacluar tumor"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_10 ; owl:annotatedTarget "Mortification"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_129 ; owl:annotatedTarget "epithelial dysplasia"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_332 ; owl:annotatedTarget "Tumor of the ovary or testis containing granulosa or theca cell elements with a tubular componant of Sertoli cell type and producing simultaneous androgenic and estrogenic effects. (M-8631/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_332 ; owl:annotatedTarget "Gynandroblastoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_333 ; owl:annotatedTarget "sex cord tumor"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_334 ; owl:annotatedTarget "Derived from sex cord stromal cells, spindle shaped cells arranged in whorls or interlacing bundles. (M- 8600/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_334 ; owl:annotatedTarget "Fibrothecoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_334 ; owl:annotatedTarget "theca cell tumor"^^xsd:string . [] oboInOwl:hasDbXref "URL:http://www.bloodjournal.org/cgi/content/full/100/1/238/DC1/2"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_335 ; owl:annotatedTarget "Proliferative disorders and malignancies of the lymphoid and non lymphoid haematopoietic lineages."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_336 ; owl:annotatedTarget "leukaemia"^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070033"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_337 ; owl:annotatedTarget "Leukaemia with at least 50% of nucleated erythroid cells infiltrating haematopoietic tissue."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_338 ; owl:annotatedTarget "granulocytic leukaemia"^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_13 ; owl:annotatedTarget "Sensu; hepaticobiliary system. Loss and degeneration of hepatocytes at the portal-lobular interface producing a moth-eaten irregular appearance. Piecemeal necrosis is associated with a lymphocytic infiltrate."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_339 ; owl:annotatedTarget "lymphatic leukaemia"^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_34 ; owl:annotatedTarget "Extracellular deposition of amyloid protein."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_34 ; owl:annotatedTarget "Amyloidosis"^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070033"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_340 ; owl:annotatedTarget "Leukaemia with at least 50% of megakaryocytic cells infiltrating haematopoietic tissue."^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070033"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_341 ; owl:annotatedTarget "Haematopoietic proliferation with evidence of trilineage dysplasia. Less than 20% should be blasts."^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070033"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_342 ; owl:annotatedTarget "Leukaemias of the myeloid lineage."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_342 ; owl:annotatedTarget "granulocytic leukaemia"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_343 ; owl:annotatedTarget "lymphoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_344 ; owl:annotatedTarget "follicle center cell lymphoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_345 ; owl:annotatedTarget "immunoblastic lymphoma"^^xsd:string . [] oboInOwl:hasDbXref "Journal: Ward; J.M. ( 2002) J Toxicol. Pathol. 15; 123-128"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_130 ; owl:annotatedTarget "Mild non-invasive changes in cell morphology and tissue architecture confined to the epithelium alone."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_347 ; owl:annotatedTarget "small lymphocytic lymphoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_348 ; owl:annotatedTarget "thymic lymphoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_349 ; owl:annotatedTarget "mast cell tumor"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_35 ; owl:annotatedTarget "Intra- or extracellular deposition of bile pigments and their metabolites."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_350 ; owl:annotatedTarget "mastocytoma"^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_351 ; owl:annotatedTarget "A neoplasm in the anterior mediastinum, originating from thymic tissue, usually benign, and frequently encapsulated; occasionally invasive, but metastases are rare; histologically, consists of any type of thymic epithelial cell as well as lymphocytes that are usually abundant. (M-8580/1)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_352 ; owl:annotatedTarget "Tumors of the liver and biliary apparatus."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_353 ; owl:annotatedTarget "Benign neoplasm derived from hepatocytes. (M- 8170/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_353 ; owl:annotatedTarget "hepatic adenoma, benign, liver cell tumor, benign"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_353 ; owl:annotatedTarget "hepatoma, benign"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_130 ; owl:annotatedTarget "IENI"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_353 ; owl:annotatedTarget "nodule type A"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_354 ; owl:annotatedTarget "Malignant tumor derived from the bile duct epithelium. (M8160/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_355 ; owl:annotatedTarget "Develops from cholangiofibrosis, fibrosis of the biliary ducts and is only potentially malignant."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_356 ; owl:annotatedTarget "Malignant neoplasm of the liver of unknown origin . Liver blastemal cells, neoplastic hepatocytes, oval cells and biliary epithelial cells have been proposed. (M- 8970/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_356 ; owl:annotatedTarget "embryonal hepatoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_356 ; owl:annotatedTarget "tumor, mixed, poorly differentiated"^^xsd:string . [] oboInOwl:hasDbXref "Book: Bannasche; P and Zerban; H. Preneoplastic and neoplastic lesions of the rat iver. In; Pathology of neoplasia and preneoplasia in rodents; P. Bannasch and W. Goessner; Editors. 1997. Schattauer; Stuttgart. p. 18-63"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_357 ; owl:annotatedTarget "Malignant tumor derived from hepatocytes. (M- 8170/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_357 ; owl:annotatedTarget "carcinoma, trabecular"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_357 ; owl:annotatedTarget "carcinoma, trabecular (liver)"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_357 ; owl:annotatedTarget "hepatoma, malignant"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_130 ; owl:annotatedTarget "low grade intraepithelial lesion"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_357 ; owl:annotatedTarget "nodule type B"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_358 ; owl:annotatedTarget "Tumors derived from melanocytes."^^xsd:string . [] oboInOwl:hasDbXref "Book: Klein-Szanto; A.J.; Neoplastic and preneoplastic lesions of the mouse skin; in Pathology of neoplasia and preneoplasia in rodents; P. Bannasch and W. Goessner; Editors. 1997. Schattauer; Stuttgart. p. 1-18"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_359 ; owl:annotatedTarget "Tumor of neurectodermal origin, usually melanocytes, showing dense deposition of melanin granules, although amelanotic melanomas have been reported. (M-8720/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_359 ; owl:annotatedTarget "melanosarcoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_359 ; owl:annotatedTarget "melanosarcoma, malignant melanoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_36 ; owl:annotatedTarget "Intra or extracellular deposition of calcium usually as calcium phosphate."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_360 ; owl:annotatedTarget "A potentially malignant lesion, melanoma in situ is the first phase of growth of melanoma, in which it is still confined to the epithelial domain (epidermis and adnexa) and has not passed through the basement membrane. (M-8720/2)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_360 ; owl:annotatedTarget "level I melanoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_361 ; owl:annotatedTarget "Local lesion of the skin, often colored by hyperpigmentation or increased vascularity. May be predominantly epidermal, adnexal, melanocytic, vascular, or mesodermal, or a compound overgrowth of these tissues. Not necessarily pre-malignant. (M-8720/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_361 ; owl:annotatedTarget "mole (sensu melanocytic nevus)"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_130 ; owl:annotatedTarget "mild epithelial dysplasia."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_362 ; owl:annotatedTarget "Benign or malignant neoplasm of the ovary and corpus uteri, thought to originate in mesonephric structures. (M-9110/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_362 ; owl:annotatedTarget "mesonephric adenocarcinoma, wolffian duct carcinoma, mesonephroid tumor"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_363 ; owl:annotatedTarget "Tumor beleived to be derived from mesonephric remnants. (M-8310/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_363 ; owl:annotatedTarget "mesonephroid clear cell adenocarcinoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_364 ; owl:annotatedTarget "mesothelial tumor"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_365 ; owl:annotatedTarget "Benign or malignant neoplasm derived from the lining cells of the pleura and peritoneum, composed of spindle cells or fibrous tissue which may enclose glandlike spaces lined by cuboidal cells. Epithelioid, fibrous, cystis, papillary, and sarcomatoid variants. (M- 9050/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_366 ; owl:annotatedTarget "Neoplasms derived from the neuroendocrine system."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_367 ; owl:annotatedTarget "Carcinoid tumors are of neuroendocrine origin and derived from primitive stem cells. Found predominantly in the lung and gut they are capable of secreting a large range of substances and have a number of histological subtypes. May resemble but are distinct from small cell lung carcinoma in the lung. (M-8240/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_368 ; owl:annotatedTarget "obsolete."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_369 ; owl:annotatedTarget "endocrine adenoma"^^xsd:string . [] oboInOwl:hasDbXref "Journal: Ward; J.M. ( 2002) J Toxicol. Pathol. 15; 123-128"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_131 ; owl:annotatedTarget "Moderate non-invasive changes in cell morphology and tissue architecture confined to the epithelium alone."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_37 ; owl:annotatedTarget "Intracellular deposition of golden or yellow-brown pigment, acid fast and insoluble in lipid solvents. Believed to be a type of lipofuscin."^^xsd:string . [] oboInOwl:hasDbXref "ISBN-13:9783794515530"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_370 ; owl:annotatedTarget "Primitive neuroectodermal tumors (PNET) are neoplasms derived from primitive neural stem cells either in the CNS or the periphery . These are small-cell, malignant embryonal tumors showing divergent differentiation of variable degree along neuronal, glial, or rarely mesenchymal lines. (M-9473/3, M-9364/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_370 ; owl:annotatedTarget "PNET"^^xsd:string . [] oboInOwl:hasDbXref "PMID:15059877"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_371 ; owl:annotatedTarget "Neuroendocrine cell derived anaplastic carcinoma composed of small cells, usually of the lung producing a variety of peptide hormones. (M-8041/3). 1.2.3.4 of MMHCC classification."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_371 ; owl:annotatedTarget "oat cell carcinoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_372 ; owl:annotatedTarget "Small disseminated foci of atypical bronchiolar epithelial hyperplasia. Benign. (M- 8040/1)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_373 ; owl:annotatedTarget "Neoplasms derived from neuroepithelial precursors."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_374 ; owl:annotatedTarget "A neoplasm of immature, poorly differentiated neuronal cells believed to arise from neuroepithelial precursors in the olfactory epithelium. (M- 9522/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_374 ; owl:annotatedTarget "neuroblastoma, olfactory"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_374 ; owl:annotatedTarget "neuroepithelial carcinoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_131 ; owl:annotatedTarget "IENII"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_374 ; owl:annotatedTarget "neuroepithelioma, olfactory"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_375 ; owl:annotatedTarget "A benign neoplasm composed of mature ganglionic neurons scattered singly or in clumps within a relatively abundant and dense stroma of neurofibrils and collagenous fibers. (M-9490/0)."^^xsd:string . [] oboInOwl:hasDbXref "ISBN-13:9783794515530"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_376 ; owl:annotatedTarget "A malignant neoplasm characterized by immature, poorly differentiated nerve cells of embryonic type. (M-9500/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_377 ; owl:annotatedTarget "A catecholamine-secreting tumor arising from the chromaffin cells of the sympathetic nervous system or adrenal medulla. May be benign or malignant. [See MPATH 398]. (M- 8510/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_378 ; owl:annotatedTarget "Malignant juvenile neoplasm of the eye derived from primitive retinal precursor cells. (M- 9510/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_379 ; owl:annotatedTarget "Neoplasm arising from the tissues of the odontogenic apparatus. These tumors are derived from ectodermal tissue (epithelial tumors) or from mesodermal tissue (connective tissue tumors) or are composed of both components (mixed or composite odontogenic tumors) ."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_38 ; owl:annotatedTarget "Intra and extracellular deposition of copper and copper containing proteins."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_380 ; owl:annotatedTarget "A tumor consisting of proliferating strands and clumps of odontogenic epithelium in a highly cellular fibroblastic stroma resembling the dental papilla of developing teeth. The epithelial component are composed of peripheral cuboidal or cylindrical cells enclosing scant stellate cells. (M-9330/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_381 ; owl:annotatedTarget "Benign odontogenic epithelial neoplasm that histologically mimics the embryonic enamel organ but does not differentiate to the point of forming dental hard tissue. Histologically dominated by epithelial cells in a scant fibroblastic stroma. (M-9310/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_382 ; owl:annotatedTarget "Benign neoplasm derived from pluripotential mesenchymal cells or cementoblasts. Well demarcated tumor occurring exclusively in the jaw containing spindle cells which undergo transformation to cuboidal cementoblasts forming multiple cementicle like bodies. ( M-9274/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_131 ; owl:annotatedTarget "high grade intraepithelial lesion"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_382 ; owl:annotatedTarget "ossifying fibroma, cemento-ossifying fibroma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_383 ; owl:annotatedTarget "A neoplasm arising from the periodontal ligament (M-9273/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_383 ; owl:annotatedTarget "True cementoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_384 ; owl:annotatedTarget "Reactive fibro-osseous lesion derived from odotongenic cells in the periodontal ligament (M-9272/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_385 ; owl:annotatedTarget "Similar lesion to ameloblastic fibroma (MPATH380) , but also showing inductive changes that lead to the formation of dentine (M-9271/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_385 ; owl:annotatedTarget "ameloblastic fibrodentinoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_386 ; owl:annotatedTarget "odontogenic tumor"^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_387 ; owl:annotatedTarget "Hamartomatous malformation of odontogenic tissue. It may vary from nondescript masses of dental tissue (complex odontoma) to multiple well-formed teeth (compound odontoma). Cf ameloblastic fibro-odontoma. (M-9280/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_388 ; owl:annotatedTarget "Neoplasms of bone and cartilage."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_389 ; owl:annotatedTarget "A benign or malignant neoplasm occuring in the epiphyses of long bones, consisting of highly cellular tissue resembling embryonic cartilage. (M-9230/0, /3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_131 ; owl:annotatedTarget "moderate epithelial dysplasia"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_39 ; owl:annotatedTarget "Intracellular deposition of glycogen."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_390 ; owl:annotatedTarget "chondroblastoma, malignant"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_391 ; owl:annotatedTarget "A benign neoplasm derived from mesodermal cells that form cartilage composed of well differentiated hyaline cartilage (M-9220/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_392 ; owl:annotatedTarget "Malignant neoplasm derived form pluripotential mesenchymal cells, chondrocytes or chondroblasts. No production of osteoid. (M-9220/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_393 ; owl:annotatedTarget "Generally benign osteogenic neoplasm of unknown aetiology. Aggressive form may be confused with osteosarcoma. NOT a syn for osteofibroma. (M-9200/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_393 ; owl:annotatedTarget "giant osteoid osteoma, benign osteoblastoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_394 ; owl:annotatedTarget "Benign bone tumor characterized by hyaline cartilage capped bony growths that project from the surface of the affected bone. (M-9210/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_394 ; owl:annotatedTarget "cartilaginous exostosis"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_395 ; owl:annotatedTarget "Benign neoplasm derived from pluripotential mesenchymal stem cells or osteoblasts composed of mature nbone trabelculae seperated by a stroma of spindle cells. (M- 9262/0)."^^xsd:string . [] oboInOwl:hasDbXref "Book: Luz; A and Gessner; W. ; Neoplastic bone lesions of the mouse; in Pathology of neoplasia and preneoplasia in rodents; P. Bannasch and W. Goessner; Editors. 1997. Schattauer; Stuttgart. p. 142-154"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_396 ; owl:annotatedTarget "Benign neoplasm derived from osteoblasts or osteocytes composed of very dense bone with predominantly woven structure. ( M-9180/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_100 ; owl:annotatedTarget "Defect in placental growth, differentiation of circulation; maternal or embryonic component."^^xsd:string . [] oboInOwl:hasDbXref "Journal: Ward; J.M. ( 2002) J Toxicol. Pathol. 15; 123-128"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_132 ; owl:annotatedTarget "Severe non-invasive malignancy associated changes in cell morphology and tissue architecture confined to the epithelium alone."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_396 ; owl:annotatedTarget "cancellous osteoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_396 ; owl:annotatedTarget "compact osteoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_396 ; owl:annotatedTarget "juxtacortical osteoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_396 ; owl:annotatedTarget "medullary osteoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_396 ; owl:annotatedTarget "osteoid osteoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_396 ; owl:annotatedTarget "spongious osteoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_396 ; owl:annotatedTarget "trabecular osteoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_397 ; owl:annotatedTarget "Malignant neoplasm derived form mesenchymal stem cells, osteoblasts or osteocytes. Highly invasive and destructive tumor rising in the skeleton with osteoid and immature woven bone. (M-9180/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_397 ; owl:annotatedTarget "osteogenic sarcoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_398 ; owl:annotatedTarget "Generally benign neoplasms of CHIEF cells arising from neuroectodermal tissues, found in various parts of the body. Note that until recently, glomus tumors were believed to be derived from specialised vascular cells, which is incorrect. Paraganglioma is the preferred term.The nomenclature for pheochromocytoma and paraganglioma is inconsistent. The term paraganglioma is used to refer to any extra-adrenal tumor of the paraganglion system or nonfunctional tumor of the paraganglion system. Functional tumors are referred extra-adrenal pheochromocytoma."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_132 ; owl:annotatedTarget "IENIII"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_399 ; owl:annotatedTarget "Paraganglioma arising in the CHIEF cells of the aortic body (M-8691/1)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_399 ; owl:annotatedTarget "aortic body paraganglioma"^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_4 ; owl:annotatedTarget "Morpholological changes after intravital (Pathologic) death of one or more cells, or of a portion of tissue or organ, resulting from irreversible damage;characterised by mitochondrial swelling, nuclear pyknosis, karyolysis, swollen and abnormally pale basophilic staining; or karyorrhexis, rupture and fragmentation of the nucleus. Energy independent cf. Apoptosis MPATH 3."^^xsd:string . [] oboInOwl:hasDbXref "PMID: 11794381"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_40 ; owl:annotatedTarget "Intracellular deposition of eosinophilic material."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_40 ; owl:annotatedTarget "Hyaline degeneration, Eosinophilic cytoplasmic change"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_400 ; owl:annotatedTarget "Paraganglioma arising in the CHIEF cells of the carotid body (M-8692/1)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_400 ; owl:annotatedTarget "carotid body paraganglioma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_401 ; owl:annotatedTarget "A glomus tumor arising from the chief cells of the paraganglia ( neurectodermal derivatives) , or glomus bodies, located within the wall (adventitia) of the jugular bulb. (8690/1)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_402 ; owl:annotatedTarget "glomus tumor"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_403 ; owl:annotatedTarget "A neoplasm composed of derivatives of CHIEF cells usually in single encapsulated nodular masses surrounded with sustentacular cells. ( M- 8711/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_132 ; owl:annotatedTarget "carcinoma in situ"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_403 ; owl:annotatedTarget "chemodectomas"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_403 ; owl:annotatedTarget "glomus tumor"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_403 ; owl:annotatedTarget "non-chromaffin paragangliomas"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_404 ; owl:annotatedTarget "Neoplasms of the soft and connective tissues."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_405 ; owl:annotatedTarget "Believed to arise from primitive notochord remnants . Usually occurs along the axial skeleton and is characterised by the presence of bubble cells containing large unstained cytoplasmic vacuoles with central or eccentricc nuclei. Benign but locally invasive. (M-9370/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_406 ; owl:annotatedTarget "Highly recurrent, infiltrative skin tumors of intermediate malignancy derived from fibroblasts/fibrocytes. Human condition dermatofibrosarcoma protruberans (M-8832/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_407 ; owl:annotatedTarget "Benign neoplasm of fibroblasts/fibrocytes with poor/moderate cellularity. (M-8810/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_408 ; owl:annotatedTarget "Malignant tumor derived from pluripotential mesenchymal stem cells; fibroblasts, fibrocytes (M-8810/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_409 ; owl:annotatedTarget "Benign or maligant tumor derived from pluripotential mesenchymal stem cells showing fibrous and histiocytic differentiation (M-8830/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_41 ; owl:annotatedTarget "Extra- or intra-cellular deposition of iron, iron containing proteins or hemosiderin."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_132 ; owl:annotatedTarget "high grade intra-epithelial lesion"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_410 ; owl:annotatedTarget "Malignant or benign tumor of pluripotential mesenchymal stem cells giving rise to large multinucleated cells (M- 9251/1)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_410 ; owl:annotatedTarget "giant cell fibrous histiocytoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_411 ; owl:annotatedTarget "granular cell tumor/alveolar sarcoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_412 ; owl:annotatedTarget "Malignant tumor of unknown origin though probably myogenic due to expression of MyoD and other myogenic lineage markers. Consists of grouped polygonal tumor cells with granular eosinophilic cytoplasm arranged in an organ-like configuration separated by thin fibrovascular septa. Central areas within these nests of cells become necrotic, and the loss of architecture produces an alveolar appearance. (M-9581/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_413 ; owl:annotatedTarget "Large polygonal or round cell tumors with abundant acidophilic cytoplasm containing PAS positive granules. Found especially in the uterine cervix. Aetiology unknown. (M-9580/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_413 ; owl:annotatedTarget "myoblastoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_414 ; owl:annotatedTarget "histiocytic sarcoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_415 ; owl:annotatedTarget "Tumors derived from the lipogenic lineage or showing predominantly lipomatous differentiation."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_416 ; owl:annotatedTarget "Benign renal neoplasm composed of fat, vascular, and smooth muscle elements. Associated with tuberous sclerosis in humans. Aetiology unknown, but the combination of elements may reflect a lesion specific pattern of metaplasia. (M-8860/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_417 ; owl:annotatedTarget "Benign neoplasia derived from lipoblasts or lipocytes of white or brown fat. May be angiomatous or hibernomatous. (M- 8850/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_132 ; owl:annotatedTarget "severe epithelial dysplasia"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_418 ; owl:annotatedTarget "Malignant neoplasms which probably originate in primitive mesenchymal stem cell populations differentiating down a lipomatous pathway. (M-8850/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_419 ; owl:annotatedTarget "Neoplasms of the lymphatic vessels."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_42 ; owl:annotatedTarget "Extra or intracellular deposition of lipid."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_420 ; owl:annotatedTarget "Benign hamartomatous malformation of the lymphatic ducts. Usually found in the skin and may be superficial or deep. (M-9170/0)."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0-19-261976-4"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasBroadSynonym ; owl:annotatedSource obo:MPATH_420 ; owl:annotatedTarget "Hygroma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_421 ; owl:annotatedTarget "Characterized by benign peribronchial, perivascular, and perilymphatic proliferation of atypical smooth muscle resulting in vascular and airway obstruction, cyst formation, and a progressive decline in lung function. (M- 9174/1)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_421 ; owl:annotatedTarget "Lymphangioleiomyomatosis."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_422 ; owl:annotatedTarget "A malignant neoplasm derived from vascular tissue in which the neoplastic cells originate from the endothelial cells of lymphatic vessels. (M-9170/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_423 ; owl:annotatedTarget "Neoplasms derived from myogenic lineages or predominantly composed of cells showing myomatous differentiation."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_424 ; owl:annotatedTarget "Benign leiomyoma that invades vascular spaces. (M-8890/1)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_133 ; owl:annotatedTarget "Small organ or structure; failure to develop to normal size."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_425 ; owl:annotatedTarget "Benign neoplasm derived from smooth muscle cells. (M-8890/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_426 ; owl:annotatedTarget "Malignant tumor derived form pluripotential mesenchymal stem cells or smooth muscle cells. (M- 8890/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_427 ; owl:annotatedTarget "myoblastoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_428 ; owl:annotatedTarget "Malignant tumor of striated muscle or pluripotential mesenchymal stem cells. (M-8900/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_429 ; owl:annotatedTarget "Neoplasms resembling primitive mesenchymal tissue with a soft mucous matrix."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_43 ; owl:annotatedTarget "Intracellular deposition of brown pigment granules probably representing lipid-containing residues of lysosomal digestion. Often age related."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_430 ; owl:annotatedTarget "Angiomyxoma is a poorly circumscribed, slowly growing lesion composed of spindle-shaped and stellate cells evenly distributed in an abundant myxoid matrix. The lesion contains numerous vessels, often showing some hyalinization of their walls, and occasionally surrounded by a few smooth muscle cells. Immunohistochemically, tumor cells may express desmin and/ or smooth muscle actin (M-8841/1)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_431 ; owl:annotatedTarget "A benign neoplasm derived from pluripotential mesenchymal stem cells of connective tissue, consisting chiefly of polyhedral and stellate cells that are loosely embedded in a soft mucoid matrix. May show multiple differentiated components. (M-8840/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_432 ; owl:annotatedTarget "A malignant neoplasm derived from pluripotential mesenchymal stem cells of connective tissue, consisting chiefly of polyhedral and stellate cells that are loosely embedded in a soft mucoid matrix. (M-8840/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_433 ; owl:annotatedTarget "Neoplasms of the nerve sheath."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_133 ; owl:annotatedTarget "Developmental hypoplasia"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_434 ; owl:annotatedTarget "neurilemmoma"^^xsd:string . [] oboInOwl:hasDbXref "ISBN-13:9783794515530"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_435 ; owl:annotatedTarget "Peripheral nerve tumor consisting of chaotic arrays of wavy schwann cell bundles and fibroblasts interspersed within a matrix rich in collagen and mucopolysaccharide. (M9540/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_436 ; owl:annotatedTarget "Systemic manifestation of MPATH:435 ( M-9540/1)."^^xsd:string . [] oboInOwl:hasDbXref "ISBN-13:9783794515530"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_437 ; owl:annotatedTarget "Malignant neoplasm derived from Schwann cells. (M-9540/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_437 ; owl:annotatedTarget "malignant peripheral nerve sheath tumor"^^xsd:string . [] oboInOwl:hasDbXref "ISBN-13:9783794515530"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_438 ; owl:annotatedTarget "May be malignant or benign, Schwann cell derived tumor considered to be neurectodermal with some acquired mesenchymal features. (M-9560/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_438 ; owl:annotatedTarget "neurilemoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_438 ; owl:annotatedTarget "neurinoma, benign"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_439 ; owl:annotatedTarget "Neoplasms of synovial origin."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_44 ; owl:annotatedTarget "Intra or extracellular deposition of melanin."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_134 ; owl:annotatedTarget "An increase in cell numbers in comparison to normal as a consequence of increased cell proliferation. Non -neoplastic process."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_440 ; owl:annotatedTarget "Malignant neoplasm occurring in close association with tendon sheaths and joint capsules. Biphasic in humans , showing a mixed spindle cell and epithelioid like morphology; this is not seen in rodents to date. (M-9040/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_440 ; owl:annotatedTarget "Synovial cell sarcoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_441 ; owl:annotatedTarget "synovioma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_442 ; owl:annotatedTarget "Neoplasms of stratified squamous epithelial cells."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_443 ; owl:annotatedTarget "A benign tumor consisting of villous or arborescent outgrowths of fibrovascular stroma covered by neoplastic epithelial cells in which proliferating epithelium is invaginated beneath the surface and is more smoothly rounded. (M-8053/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_443 ; owl:annotatedTarget "endophytic papilloma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_443 ; owl:annotatedTarget "invaginated papilloma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_444 ; owl:annotatedTarget "Skin type is thought to arise from follicular epithelium of hair follicles; found in other epithelia. Composed of multiple cup shaped cavities filled with lamellated concentrically arranged or homogeneous cornified masses."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_444 ; owl:annotatedTarget "epithelioma, intracutaneous, cornifying"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_445 ; owl:annotatedTarget "A benign tumor consisting of villous or arborescent outgrowths of fibrovascular stroma covered by neoplastic epithelial cells (M-8050/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_135 ; owl:annotatedTarget "Abnormal proliferation of epithelial and stromal cells."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_446 ; owl:annotatedTarget "Malignant tumor derived from stratified squamous cells. (M-8070/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_446 ; owl:annotatedTarget "carcinoma, epidermoid ( sensu epidermal derived tumors)"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_447 ; owl:annotatedTarget "Pre-neoplastic intraepithelial lesion of squamous cells (M-8070/2)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_447 ; owl:annotatedTarget "IENIII"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_447 ; owl:annotatedTarget "severe intra-epithelial neoplasia"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_448 ; owl:annotatedTarget "A benign tumor consisting of villous or arborescent outgrowths of fibrovascular stroma covered by neoplastic squamous epithelial cells."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_448 ; owl:annotatedTarget "Exophytic papilloma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_449 ; owl:annotatedTarget "A well-differentiated papillary squamous cell carcinoma. (M-8051/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_45 ; owl:annotatedTarget "Non-specified intra or extracellular deposition of protein."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_450 ; owl:annotatedTarget "Neoplasms of transitional epithelia, eg kidney, ureter , bladder , cervix."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_136 ; owl:annotatedTarget "A polypoid outgrowth of both epidermis and dermal fibrovascular tissue."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_451 ; owl:annotatedTarget "Malignant neoplasm of transitional cells (M-8120/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_452 ; owl:annotatedTarget "Pre-malignant intra-epithelial neoplasm of transitional cells (M-8120/2)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_452 ; owl:annotatedTarget "severe intra-epithelial neoplasia"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_453 ; owl:annotatedTarget "Pre-malignant lesion of transitional cells, papillomatous form ( M- 8120/1)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_454 ; owl:annotatedTarget "Tumors derived directly from trophoblastic tissue or differentiated from germ cell tumor origins."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_455 ; owl:annotatedTarget "Tumor derived from malignant trophoblastic cells. May be found in the uterus, ovary and testis. May also be derived from teratomas and teratocarcinomas in males. (M-9100/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_455 ; owl:annotatedTarget "Chorioepithelioma, malignant."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_456 ; owl:annotatedTarget "Vesicular or cystic tumor with hydropic villi resulting from the proliferation of trophoblast in the absence ( complete) or the presence ( partial) of an embryo. Most complete moles are homozygous androgenetic XX 46.(M-9100/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_456 ; owl:annotatedTarget "cystic mole"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_456 ; owl:annotatedTarget "gestational trophoblastic disease"^^xsd:string . [] oboInOwl:hasDbXref "UOB:LTS"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_1000 ; owl:annotatedTarget "Phenotypic observation of the presence or absence of a pathological entity."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_136 ; owl:annotatedTarget "skin tag"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_457 ; owl:annotatedTarget "Neoplastic proliferation of intermediate trophoblasts that invades the myometrium at the placental site after a pregnancy. (M-9104/1)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_458 ; owl:annotatedTarget "No pathological entity observable."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_459 ; owl:annotatedTarget "obsolete"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_46 ; owl:annotatedTarget "Extracellular deposition of uric acid crystals."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_460 ; owl:annotatedTarget "Defect in the structure or function of the nuclear membrane or matrix or other component."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:08493086 4X"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_461 ; owl:annotatedTarget "Proliferation of lens epithelium and capsule leading to fibrous metaplasia and anterior subcapsular cataract ( ASC) . Possible developmental origin."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:08493086 4X"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_462 ; owl:annotatedTarget "Nuclear cataract of developmental origin with tendency to progress with age and involve the cortex and capsule."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:08493086 4X"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_463 ; owl:annotatedTarget "Of developmental origins; nucleus and cortex become completely liquefied in post-natal life."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:08493086 4X"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_464 ; owl:annotatedTarget "Involves capsular rupture usually of the posterior lens capsule, close to birth or in the first few weeks postpartum. Cortical material spills into the vitreous humor and may be disseminated through the eye."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:08493086 4X"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_465 ; owl:annotatedTarget "Consequent on developmental abnormalities in the trabecular network and Schlemm`s canal in the angle."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_137 ; owl:annotatedTarget "Benign proliferation of glandular epithelium accompanied by proliferation of fibroblastic stroma."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:08493086 4X"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_466 ; owl:annotatedTarget "Failure of drainage of the eye for unknown reasons."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:08493086 4X"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_467 ; owl:annotatedTarget "Develops when the angle caused by the iris and cornea closes. May occur because of anatomically narrow angles or adhesions."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_468 ; owl:annotatedTarget "Formation of extracellular (sensu pancreas) non-epithelial bounded spaces containing accumulated products or substances."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_469 ; owl:annotatedTarget "Any aberration of the normal symmetrical organisation of the body pattern."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_47 ; owl:annotatedTarget "Loss or dispersion of specific intra- and extracellular substances."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_470 ; owl:annotatedTarget "Left/Right (mediolateral) axis aberration of the normal symmetrical organisation of the body pattern."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_471 ; owl:annotatedTarget "Anteroposterior aberration of the normal symmetrical organisation of the body pattern."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_472 ; owl:annotatedTarget "Dorsoventral aberration of the normal symmetrical organisation of the body pattern."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_473 ; owl:annotatedTarget "Developmental dysplasia showing epithelial cell bounded cavities."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_474 ; owl:annotatedTarget "Dilation of a tubular structure."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_138 ; owl:annotatedTarget "Abnormal proliferation of epithelial cells and epithelial components."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_475 ; owl:annotatedTarget "Dilation of a ductal structure."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_476 ; owl:annotatedTarget "A lesion formed by a dilated capillary or terminal artery."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_477 ; owl:annotatedTarget "Similar to hamartoma, including the mass lesion requirement, but unlike hamartoma, includes heterotopic tissue of an adult or embryonic nature ( topographical and developmental anomaly)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_477 ; owl:annotatedTarget "Choristoblastoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_478 ; owl:annotatedTarget "Abnormality in developmental angiogenesis."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_479 ; owl:annotatedTarget "Defect in formation of blood vessels by vasculogenesis, proliferation or recruitment of endothelial cells."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_48 ; owl:annotatedTarget "Process of loss of calcium from normally calcified tissue, usually bone."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_480 ; owl:annotatedTarget "Any defect in the formation, architecture, cellular composition or function of the maternal decidua."^^xsd:string . [] oboInOwl:hasDbXref "Journal: Ward; J.M. ( 2002) J Toxicol. Pathol. 15; 123-128"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_481 ; owl:annotatedTarget "Lesions likely to result in progression to frank tumors, which may be classified as pre-neoplastic or pre-cancerous."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_482 ; owl:annotatedTarget "Localised hyperplastic lesion. Polyclonal lesions are probably benign but clonal lesions may progress to malignancy."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_139 ; owl:annotatedTarget "Benign proliferation of goblet cells."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_483 ; owl:annotatedTarget "Presence of localised areas within for example adenomas showing characteristics of neoplastic (tumor) progression, eg focal carcinoma."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_484 ; owl:annotatedTarget "Expansion of small hyperplastic lesions to become macroscopically nodules, compressing adjacent cells."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_484 ; owl:annotatedTarget "hyperplastic nodules"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_485 ; owl:annotatedTarget "May be used in some systems in preference to its synonyms to indicate lesion specific aprearances. A lesion characterised by changes of the type associated with invasive carcinoma, but physically bounded by the lining epithelium and without local invasion."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_485 ; owl:annotatedTarget "severe epithelial dysplasia"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_485 ; owl:annotatedTarget "severe intraepithelial neoplasia"^^xsd:string . [] oboInOwl:hasDbXref "PMID:10713680"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_486 ; owl:annotatedTarget "Pre-malignant hyperplastic and/or dysplastic change in the mammary gland epithelium with the potential to give rise to malignant tumors."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_486 ; owl:annotatedTarget "DIN"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_486 ; owl:annotatedTarget "Ductal carcinoma in situ"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_486 ; owl:annotatedTarget "MIN"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_14 ; owl:annotatedTarget "A pathological process of loss or degradation of function, or structural integrity, of a tissue, organ or cell."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_486 ; owl:annotatedTarget "intraductal adenocarcinoma, non-infiltrating"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_486 ; owl:annotatedTarget "mammary intra-epithelial neoplasia"^^xsd:string . [] oboInOwl:hasDbXref "PMID:12612914"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_487 ; owl:annotatedTarget "Histologically apparent areas of dysplasia that are not grossly visible (smaller than 0.5-1 mm). Lesions may involve single or multiple glands."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_487 ; owl:annotatedTarget "GIN"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_487 ; owl:annotatedTarget "IIN"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_487 ; owl:annotatedTarget "microadenoma"^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0-19-512338-7"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_488 ; owl:annotatedTarget "See reference for definition."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_488 ; owl:annotatedTarget "PIN"^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0-19-512338-7"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_489 ; owl:annotatedTarget "stomach, oesophagus and pancreatic intra-epithelial neoplasia"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_489 ; owl:annotatedTarget "PANIN"^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_140 ; owl:annotatedTarget "A benign polyp, usually in the colon, showing hyperplasia."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_49 ; owl:annotatedTarget "Reduction of myelin content in neuronal sheath."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_490 ; owl:annotatedTarget "Benign neoplastic growth containing areas of adenomatous structure (progression)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_490 ; owl:annotatedTarget "polypoid adenoma, cellular polyp."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_491 ; owl:annotatedTarget "A mass of tissue which projects outward or upward from the normal surface level being macroscopically visible as a hemispheroidal, spheroidal, or irregular moundlike structure growing from a relatively broad base or a slender stalk."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_492 ; owl:annotatedTarget "Glomerulonephritis characterized by diffuse thickening of glomerular capillary basement membranes, due in part to subepithelial deposits of immunoglobulins separated by spikes of basement membrane material,."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_493 ; owl:annotatedTarget "A chronic glomerulonephritis characterized by mesangial cell proliferation, increased lobular separation of glomeruli, thickening of glomerular capillary walls and increased mesangial matrix,."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_494 ; owl:annotatedTarget "Glomerulonephritis caused by autoimmune attack on the glomerulus."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_495 ; owl:annotatedTarget "Tumor derived from the capillary glomus with arteriovenous capillary anastomoses. Often characterized by multiple tumors resembling cavernous hemangioma (M-8712/0)."^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070033"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_496 ; owl:annotatedTarget "Neoplasms of non-lymphoid haematopoietic lineage. Must have at least 20% blast cells to meet this definition."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_141 ; owl:annotatedTarget "A projecting mass of granulation tissue which may become covered by regenerating epithelium."^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070033"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_497 ; owl:annotatedTarget "Leukaemia in which neoplastic cells are poorly differentiated and not monocytic. At least 90% of the cells have to be blasts."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_497 ; owl:annotatedTarget "myeloblastic leukaemia without maturation"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_497 ; owl:annotatedTarget "myeloid leukaemia (myeloblastic type)"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_497 ; owl:annotatedTarget "poorly differentiated myeloid leukaemia"^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070033"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_498 ; owl:annotatedTarget "Leukaemia in which neoplastic cells are moderately differentiated with a neutrophilic but not monocytic component. At least 20% of the cells have to be blasts."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_498 ; owl:annotatedTarget "myeloblastic laeukaemia with maturation"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_498 ; owl:annotatedTarget "poorly differentiated myeloid leukaemia"^^xsd:string . [] oboInOwl:hasDbXref "PMCID: 1964945"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_499 ; owl:annotatedTarget "Abnormal proliferation of beta cells of developing islets often leading to marked diffuse or focal beta-cell hyperplasia. Considered to generate a potentially cancerous lesion."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_499 ; owl:annotatedTarget "Beta-cell nesidioblastosis"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_499 ; owl:annotatedTarget "congenital insulinomas"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_141 ; owl:annotatedTarget "pseudopolyp"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_499 ; owl:annotatedTarget "diffused or generalised islet cell hyperplasia"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_499 ; owl:annotatedTarget "endocrine dysplasia"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_499 ; owl:annotatedTarget "focal adenomatosis"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_499 ; owl:annotatedTarget "microadenomatosis"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_499 ; owl:annotatedTarget "multifocal and focal ductulo-insular proliferation (nesidioblastosis)"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_499 ; owl:annotatedTarget "nesidioblastoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_499 ; owl:annotatedTarget "nesidiodysplasia"^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_5 ; owl:annotatedTarget "Area of liver necrosis that bridges adjacent portal areas and central veins."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_50 ; owl:annotatedTarget "Reduction in intracellular glycogen content."^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070033"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_500 ; owl:annotatedTarget "Leukaemia in which neoplastic cells are well differentiated and in which there are fewer than 20% blasts."^^xsd:string . [] oboInOwl:hasDbXref "PMID:10713680"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_142 ; owl:annotatedTarget "Benign hyperplasia of the ducts of the mammary gland. Ducts exhibit more than the usual two layer epithelium (inner cuboidal to columnar cells; outer layer of myoepithelium) without cytological atypia."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_500 ; owl:annotatedTarget "myeloid leukaemia, chonic type"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_500 ; owl:annotatedTarget "well differentiated myeloid leukaemia"^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070033"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_501 ; owl:annotatedTarget "Leukaemia in which neoplastic cells are moderately differentiated with a neutrophilic and a monocytic component. At least 20% of the cells have to be blasts."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_501 ; owl:annotatedTarget "myeloid leukaemia, myelomonocytic type"^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070033"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_502 ; owl:annotatedTarget "Leukaemia in which neoplastic cells are poorly or moderately differentiated with a monocytic but no neutrophilic component. At least 20% of the cells must be blasts."^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070033"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_503 ; owl:annotatedTarget "A leukaemia with at least 90% blasts and differentiation markers of the myeloid and lymphoid lineage."^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070033"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_504 ; owl:annotatedTarget "Solid tumor mass composed of non-lymphoid haematopoietic cells."^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070033"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_505 ; owl:annotatedTarget "Solid tumor mass composed predominantly of granulocytic or relatively undifferentiated non-lymphoid haematopoietic cells."^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070033"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_506 ; owl:annotatedTarget "Solid tumor mass composed predominantly of histiocytic cells (M-9775/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_506 ; owl:annotatedTarget "Kupffer cell sarcoma (sensu liver)"^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_143 ; owl:annotatedTarget "Benign proliferation of glandular epithelia, eg. Endocervical glands. Consists of tightly packed glandular or tubular units, which vary in size, lined by a flattened-to-cuboidal epithelium."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_506 ; owl:annotatedTarget "histiocytic lymphoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_506 ; owl:annotatedTarget "malignant lymphoma, histiocytic type"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_506 ; owl:annotatedTarget "reticulum cell sarcoma, type A"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_506 ; owl:annotatedTarget "reticulum cell sarcoma, type A, reticulosarcoma"^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070033"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_507 ; owl:annotatedTarget "Solid tumor mass composed of mast cells."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_507 ; owl:annotatedTarget "malignant mastocytoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_507 ; owl:annotatedTarget "mast cell tumor"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_507 ; owl:annotatedTarget "mastocytosis"^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070033"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_508 ; owl:annotatedTarget "Haematopoietic proliferation with evidence of trilineage dysplasia."^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070033"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_509 ; owl:annotatedTarget "Haematopoietic proliferation with evidence of trilineage dysplasia. More than 20% should be blasts."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_101 ; owl:annotatedTarget "Lack of, displacement of, or abnormality in function or growth of the glycogen cells."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_143 ; owl:annotatedTarget "microglandular adenosis"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_51 ; owl:annotatedTarget "Intrinsic abnormally low level of calcification in a tissue cf. MPATH: 48."^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070033"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_510 ; owl:annotatedTarget "Non-reactive persistent accumulation of non-lymphoid haematopoietic cells. Genetically determined."^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070033"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_511 ; owl:annotatedTarget "Non-reactive persistent accumulation of non-lymphoid haematopoietic cells in the blood which do not infiltrate the spleen and the bone marrow. Genetically determined."^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070033"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_512 ; owl:annotatedTarget "Non-reactive persistent accumulation of non-lymphoid haematopoietic cells in the blood which infiltrate the spleen and the bone marrow."^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070034"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_513 ; owl:annotatedTarget "Neoplasms of the B or T cell lineage."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_514 ; owl:annotatedTarget "B cell neoplasms"^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070033"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_515 ; owl:annotatedTarget "Hematological neoplasias of non-lymphoid origin."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_516 ; owl:annotatedTarget "Neoplasm of the B cell lymphoid lineage."^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070034"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_517 ; owl:annotatedTarget "Lymphoma originating from precursor B-cells."^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070034"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_518 ; owl:annotatedTarget "Lymphoma originating in a precursor B-cell."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_144 ; owl:annotatedTarget "Benign proliferation of glandular myoepithelial cells."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_518 ; owl:annotatedTarget "lymphoblastic leukaemia"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_518 ; owl:annotatedTarget "lymphoblastic lymphoma"^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070034"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_519 ; owl:annotatedTarget "Lymphomas originating in peripheral B cells."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_52 ; owl:annotatedTarget "Reduction in cellular or plasma lipid content."^^xsd:string . [] oboInOwl:hasDbXref "Book: Morse; et al. (2002) Blood 100; 246-258"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_520 ; owl:annotatedTarget "Diffuse accumulation of small mature B-cells."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_520 ; owl:annotatedTarget "small lymphocytic lymphoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_520 ; owl:annotatedTarget "well differentiated lymphocytic lymphoma"^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070034"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_521 ; owl:annotatedTarget "A lymphoid proliferation of cells of the marginal zone of the white pulp of the spleen."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_521 ; owl:annotatedTarget "SMZL"^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070034"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_522 ; owl:annotatedTarget "A lymphoid proliferation composed of a mixture of centroblasts and centrocytes that may or may not have a nodular(follicular)pattern. The follicular dendritic cell network is not present, unlike in the human. The equivalent typical translocation (Chr. 14:18 )seen in humans has not been reported in the mouse."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_145 ; owl:annotatedTarget "Benign proliferation of adipose tissue."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_522 ; owl:annotatedTarget "centroblastic/centrocytic lymphoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_522 ; owl:annotatedTarget "follicular center cell lymphoma, small cell or mixed"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_522 ; owl:annotatedTarget "follicular lymphoma"^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070034"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_523 ; owl:annotatedTarget "Diffuse proliferation of large B lymphoid cells."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_523 ; owl:annotatedTarget "DLBCL"^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070034"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_524 ; owl:annotatedTarget "Diffuse follicular centre cell lymphoma mainly composed of centroblasts."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_524 ; owl:annotatedTarget "centroblastic lymphoma"^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070034"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_525 ; owl:annotatedTarget "Diffuse large B cell lymphoma with increased number of immunoblasts."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_525 ; owl:annotatedTarget "Immunoblastic lymphoma"^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070034"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_526 ; owl:annotatedTarget "Diffuse large B-cell lymphoma with more than 50% histiocytes."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_147 ; owl:annotatedTarget "Benign enlargement of lymphoid tissues."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_526 ; owl:annotatedTarget "DLCL (HS)"^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070034"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_527 ; owl:annotatedTarget "Primary B-cell lymphoma of the thymus. Reported in C57BL/6 mice infected with replication defective MuLV. Not clear that this is the equivalent of the human disease."^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070034"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_528 ; owl:annotatedTarget "Highly proliferative B-cell lymphoma characteristically seen in c-Myc transgenic mice, derived from mature B cells."^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070034"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_529 ; owl:annotatedTarget "Highly proliferative mature B-cell lymphoma, poorly defined."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_53 ; owl:annotatedTarget "Reduced bone mass due to inadequate synthesis of osteoid, resulting in decreased calcification."^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070034"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_530 ; owl:annotatedTarget "Diffuse proliferation of mature plasma cells. Clonal by definition. Includes the equivalent of human myeloma (ICD-O 9732/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_530 ; owl:annotatedTarget "Myeloma ( human )"^^xsd:string . [] oboInOwl:hasDbXref "Lu; L-M.; et al (1999) Jpn J. Cancer Res. 90: 1218-1223"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_531 ; owl:annotatedTarget "Unusual lymphoma type described in thymectomised (SL/Kh x AKR/Ms) F1 mice. No equivalent found in human to date. See reference for detailed phenotype."^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070034"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_532 ; owl:annotatedTarget "Diffuse proliferation of mature plasma cells. Clonal by definition."^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070034"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_533 ; owl:annotatedTarget "Diffuse proliferation of mature plasma cells. Clonal by definition. Frequently found in IL6 transgenic mice. Characteristically involves spleen and nodes rather than peritoneum."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_147 ; owl:annotatedTarget "lymphoid hypertrophy"^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070034"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_534 ; owl:annotatedTarget "Diffuse proliferation of immature plasma cells or plasma blasts."^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070034"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_535 ; owl:annotatedTarget "Neoplasms derived from cells of the T lymphocyte lineage."^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070034"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_536 ; owl:annotatedTarget "Neoplasms of precursor T cells."^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070034"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_537 ; owl:annotatedTarget "Precursor T cell derived neoplasia. Most commonly found in the thymus."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_537 ; owl:annotatedTarget "thymic lymphoma"^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070034"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_538 ; owl:annotatedTarget "Non-thymic neoplasms of mature T cell origin."^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070034"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_539 ; owl:annotatedTarget "Accumulation of small mature T cells. No human counterpart known to date."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_54 ; owl:annotatedTarget "Reduction in the quantity of bone or atrophy of skeletal tissue. More severe than MPATH: 53 with gross changes to bone matrix."^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070034"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_540 ; owl:annotatedTarget "T cell neoplasms which cannot currently be classified into known subtypes."^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070034"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_541 ; owl:annotatedTarget "Diffuse large pleiomorphic T cell lymphoma. This entity does not correspond to human anaplastic large cell lymphoma."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Mohr"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_148 ; owl:annotatedTarget "Benign proliferation of mesothelial cells lining body cavities presenting as small solid cell clusters or multiple layers with columnar morphology and delicate eosinophilic cytoplasm."^^xsd:string . [] oboInOwl:hasDbXref "PMID:12070034"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_542 ; owl:annotatedTarget "Neoplasm of large granular T cells of CD8 phenotype."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_543 ; owl:annotatedTarget "Benign neoplasm of the biliary duct. Occurs in solid and cystic forms. (M-8160/0)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_544 ; owl:annotatedTarget "Benign tumor of unknown origin showing features of hepatocelluar adenoma and cholangioma."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_545 ; owl:annotatedTarget "Malignant tumor of unknown origin showing features of hepatocelluar carcinoma and cholangiocarcinoma. (M-8180/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_547 ; owl:annotatedTarget "Extracellular accumulation of mucous secretions."^^xsd:string . [] oboInOwl:hasDbXref "Book: Kunze; E. (1994) Preneoplastic and neoplastic lesions of the Rat urinary bladder. In; Pathology of Neoplasia and Preneoplasia in Rodents. Eds. Bannach; P.; and Goessner; W.; Vol 1 p 114. Schattauer; Stuttgart New York"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_548 ; owl:annotatedTarget "A generally malignant neoplasm consisting of villous or arborescent outgrowths of fibrovascular stroma covered by atypical neoplastic epithelial or urothelial cells cells."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_549 ; owl:annotatedTarget "Any of various types of malignant neoplasm derived from epithelial cells, chiefly glandular (adenocarcinoma) or squamous (squamous cell carcinoma)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_55 ; owl:annotatedTarget "Developmental and structural abnormalities occurring during embryonic development or during adult life."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_550 ; owl:annotatedTarget "A connective tissue neoplasm, usually highly malignant, formed by proliferation of mesodermal cells."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_551 ; owl:annotatedTarget "A connective tissue neoplasm, usually highly malignant, formed by proliferation of mesodermal cells."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_148 ; owl:annotatedTarget "mesothelioma"^^xsd:string . [] oboInOwl:hasDbXref "Book: Hahn; F.F. and Boorman; GA. neoplasia and pre-neoplasia in the lung. In Pathology of Neoplasia and Preneoplasia in Rodents. Vol.2. p 39. (1997) Schattauer ( Stuttgart and New York)"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_552 ; owl:annotatedTarget "Benign tumor of the Clara cells of the bronchioalveolar epithelium."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_553 ; owl:annotatedTarget "Inflammation of a nerve."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_554 ; owl:annotatedTarget "Regressive changes which may increase in severity, and which may result from defective nutrition or support of a tissue or organ."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_555 ; owl:annotatedTarget "Deposition of any homogeneous inorganic material."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_556 ; owl:annotatedTarget "Lesions which in some cases have the potential to become progressively growing malignant tumors."^^xsd:string . [] oboInOwl:hasDbXref "PMID:12612914"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_557 ; owl:annotatedTarget "Sensu gastrointsestinal tract. visible microscopically in whole mount colonic tissue. One or more crypts larger than most, have a thickened layer of epithelial cells that stain more intensely with methylene blue. Some have a slit shaped luminal opening, and increased pericryptal space and are elevated from the focal plane of the microscope. ACF is not a histologic diagnosis."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_557 ; owl:annotatedTarget "ACF"^^xsd:string . [] oboInOwl:hasDbXref "PMID:10713680"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_558 ; owl:annotatedTarget "Adenocarcinoma type tumor with both glandular and squamous differentiation. (M-8983/0)."^^xsd:string . [] oboInOwl:hasDbXref "PMID:10713680"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_559 ; owl:annotatedTarget "Tumor composed of small glandular clusters with small lumens."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_56 ; owl:annotatedTarget "Structural, physical or other general defect of prenatal development of the embryo and the placenta, or such as are acquired in the adult."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_149 ; owl:annotatedTarget "Benign proliferation of epidermal cells with hyperkeratosis. Variable growth pattern, regular to papillary (exophytic squamous cell hyperplasia)."^^xsd:string . [] oboInOwl:hasDbXref "PMID:10713680"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_560 ; owl:annotatedTarget "Tumor composed of sheets or nests of cells forming lumens with round, punched out spaces."^^xsd:string . [] oboInOwl:hasDbXref "PMID:12612914"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_561 ; owl:annotatedTarget "Mixed adeno- and squamous cell carcinoma. Not yet reported in mice. M-8560/3."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_562 ; owl:annotatedTarget "The twisting of a bodily organ or part on its own axis."^^xsd:string . [] oboInOwl:hasDbXref "PMID:12612914"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_563 ; owl:annotatedTarget "carcinoma derived from gastrointestinal epithelium with a high mucinous content. (M-8480/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_563 ; owl:annotatedTarget "mucinous adenocarcinoma"^^xsd:string . [] oboInOwl:hasDbXref "ISBN-13:9783794515530"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_564 ; owl:annotatedTarget "Develop primarily through increasing anaplasia of well differentiated gliomas, mainly astrocytomas or oligodendrogliomas. Typically large and contain cells of different sizes with irrregular nuclei and atypical mitotic figures. (M-9440/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_564 ; owl:annotatedTarget "glioblastoma multiforme"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_564 ; owl:annotatedTarget "monstrocytoma"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_565 ; owl:annotatedTarget "Tumors of neuronal and non-neuronal cells derived from embryonic neurepithelium."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_566 ; owl:annotatedTarget "tumors of the meninges"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_149 ; owl:annotatedTarget "epidermal hyperplasia."^^xsd:string . [] oboInOwl:hasDbXref "Nervous System. Radovsky A and Mahler; J.S. In: Maronpot; R. Pathology of the Mouse. (1999) Cache River Press. Vienna IL"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_567 ; owl:annotatedTarget "Glial cell derived tumor composed of bipolar cells with long `hairlike` GFAP-positive processes. (M9421/1)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_567 ; owl:annotatedTarget "cystic cerebellar astrocytoma"^^xsd:string . [] oboInOwl:hasDbXref "ISBN-13:9783794515530"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_568 ; owl:annotatedTarget "Mixed tumor containing astrocytes within an oligodendroglioma or vice versa. In some cases both components may be neoplastic. (M-9382/3)."^^xsd:string . [] oboInOwl:hasDbXref "ISBN-13:9783794515530"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_569 ; owl:annotatedTarget "granular cell tumor"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_57 ; owl:annotatedTarget "Failure of a tissue or organ to develop."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_57 ; owl:annotatedTarget "Agenesia"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_570 ; owl:annotatedTarget "Tumors of the peripheral nervous system."^^xsd:string . [] oboInOwl:hasDbXref "See: Gat; U.; DasGupta; R.; Degenstein; L. and Fuchs; E. (1998) De Novo hair follicle morphogenesis and hair tumors in mice expressing a truncated beta-catenin in skin Cell; 95; 605-614."^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_571 ; owl:annotatedTarget "Tumor composed of the epithelial components of the most proximal (trichogenic) portion of the hair follicle associated with an aberrent hair cortex type of cornification (ghost cells or shadow cells). The most primitive cellular component consists of basophilic cells having scanty cytoplasm and nuclei that occasionally overlap to some extent. In humans mineralisation is common."^^xsd:string . [] oboInOwl:hasDbXref "Book: Luz A; Goessner; W.;and Murray AB.(1991) Ossifying fibroma; mouse. In; Jones TC; Mohr U; Hunt RD (eds) Monographs on pathology of laboratory animals. Cardiovascular and musculoskeletal systems. Springer; Berlin Heidelberg New York Tokyo; pp 228-232"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_572 ; owl:annotatedTarget "Ossifying fibromas are benign tumors derived from pluripotential mesenchymal stem cells or osteoblasts. Occur spontaneously or in response to radiation. Preferentially located in mandible, maxilla and caudal spine. Composed of a characteristically regular trabecular bone pattern embedded in a fibrous stroma. Proliferating component consists of spindle cells which give rise to cuboidal osteoblasts to form rounded bodies or trabeculae. Bone trabeculae resemble the alphabet soup shapes characteristic of fibrous dysplasia in humans. In contrast to fibrous dysplasia the bone trabeculae of ossifying fibroma are mostly lamellar and ringed by active osteoblasts."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_573 ; owl:annotatedTarget "Pre-malignant lesion of transitional cells, papillomatous form, in which proliferating epithelium is invaginated beneath the surface."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_149 ; owl:annotatedTarget "squamous cell hyperplasia"^^xsd:string . [] oboInOwl:hasDbXref "PMID:8383276"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_574 ; owl:annotatedTarget "Persistence of metanephrogenic blastema or its presence in the wrong place or at the wrong time. Associated with hyperplastic nephrogenic rests."^^xsd:string . [] oboInOwl:hasDbXref "URL:http://emice.nci.nih.gov/emice/mouse_models/organ_models/skin_models"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_575 ; owl:annotatedTarget "This is a new diagnostic term that the MMHC pathology panel felt best described a diagnostically challenging set of tumors that share the feature of being compose of basaloid cells showing follicular differentiation to some extent. These tumors are common in GEM involving the hedgehog signaling pathway and frequently have more than one of the histologic patterns listed below. The designation of benign and malignant has been excluded from the primary diagnosis purposely, as this is frequently difficult to determine in these characteristically well circumscribed tumors. The presence of a disorganized (non-palisaded) sheet-like growth pattern, tumor necrosis, or numerous mitoses are felt to represent malignant transformation."^^xsd:string . [] oboInOwl:hasDbXref "URL:http://emice.nci.nih.gov/emice/mouse_models/organ_models/skin_models"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_576 ; owl:annotatedTarget "Basaloid neoplasm with numerous mature hair follicles and hair formation."^^xsd:string . [] oboInOwl:hasDbXref "URL:http://emice.nci.nih.gov/emice/mouse_models/organ_models/skin_models/hierarchical_classification"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_577 ; owl:annotatedTarget "Cellular neoplasm with well formed palisades of basaloid cells adjacent to less basophilic smaller cells with occasional central deposition of amorphous eosinophilic material. These tumors share some features with cylindroma type tumors but have a less well developed jigsaw puzzle-like architecture and tend to be more cellular."^^xsd:string . [] oboInOwl:hasDbXref "URL:http://emice.nci.nih.gov/emice/mouse_models/organ_models/skin_models/hierarchical_classification"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_578 ; owl:annotatedTarget "Basaloid neoplasm with frequent primitive hair follicles."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_579 ; owl:annotatedTarget "Loss of epithelium and the basement membrane (full thickness). Cf Erosion."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_58 ; owl:annotatedTarget "Absence of an organ or tissue coupled with persistence of the organ/tissue primordium, which fails to develop completely."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_580 ; owl:annotatedTarget "Partial epithelial denudation not penetrating to the basement membrane."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_581 ; owl:annotatedTarget "Connective tissue proliferative reaction induced by a neoplastic process."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_102 ; owl:annotatedTarget "Defect in size, cellular composition, function or organisation of the labyrinthine zone of the placenta."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_15 ; owl:annotatedTarget "Change of tissue to a lower state of integrity or less functional form, as in heart failure."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_581 ; owl:annotatedTarget "scirrhous"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_581 ; owl:annotatedTarget "sclerosis"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_582 ; owl:annotatedTarget "Scarring of the hair follicle without affecting the adjacent dermis. Pigment may be associated with fibrous tract in pigmented individuals."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_583 ; owl:annotatedTarget "Loss of hair follicles in a diffuse dermal scar."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_584 ; owl:annotatedTarget "In mice the term refers to accumulation of fibrous connective tissue in the medullary cavity of bones; usually in old mice. In humans the term is synonymous with myeloid metaplasia."^^xsd:string . [] oboInOwl:hasDbXref ":Murray AB; Luz A ( 1990 ) Acidophilic macrophage pneumonia in laboratory mice. Vet Pathol. 27; 274-81"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_585 ; owl:annotatedTarget "A mixed inflammatory infiltrate in the pulmonary airways with predominant intra-alveolar macrophage component with intra- and extracellular, elongated, bright eosinophilic/acidophilic crystals."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_586 ; owl:annotatedTarget "A group of degenerative disorders resulting in multiple cysts in tissues."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_586 ; owl:annotatedTarget "polycystic kidney disease"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_586 ; owl:annotatedTarget "polycystic liver disease"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_586 ; owl:annotatedTarget "polycystic ovary"^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_150 ; owl:annotatedTarget "Hyperplasia of the Malpighian layer (prickle cell) of the epidermis."^^xsd:string . [] oboInOwl:hasDbXref "Journal: La Perle KM; Blomme EA; Sagartz JE; Capen CC (2002) Epididymal cribriform hyperplasia with nuclear atypia in p53 homozygous knockout. Comp Med. 2002 52:568-71."^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_587 ; owl:annotatedTarget "The lesion is characterized microscopically by epithelial cells with atypical hyperchromatic nuclei, vacuolization, intratubular lumina formation, infrequent apoptosis, and rare mitotic figures. In contrast to germ cells, the cells of CEH do not express alpha-fetoprotein, carcinoembryonic antigen, or S-100. Ultrastructurally, the cells are pleomorphic with stereocilia at their apical borders and within intratubular lumina, and are supported by a basement membrane. CEH does not appear to be a preneoplastic change."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_588 ; owl:annotatedTarget "Dysplasia"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_589 ; owl:annotatedTarget "Distortion or deficiency of the tissue or cellular architecture."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_59 ; owl:annotatedTarget "Defect in the process determining number, angle, pattern or rate of branching of tubular branched structures eg. Glandular ducts."^^xsd:string . [] oboInOwl:hasDbXref "Book: Albassam MA; Courtney CL (1996) Nonneoplastic and neoplastic lesions of the bone. In; Mohr U; Dungworth DL; Capen CC; Carlton WW; Sundberg JP; Ward JM (eds) Pathobiology of the aging mouse. Vol 2. Musculoskeletal system. ILSI Press; Washington D.C.; pp 425-437"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_590 ; owl:annotatedTarget "Lesion of bone showing accelerated osteoclastic bone resorption coupled with fibroplasia. Later stages show proliferation of osteoblasts."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_590 ; owl:annotatedTarget "fibrous dysplasia"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_590 ; owl:annotatedTarget "fibrous osteodystrophy"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_590 ; owl:annotatedTarget "osteodysplasia"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_590 ; owl:annotatedTarget "osteodystrophy"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_590 ; owl:annotatedTarget "osteofibrosis"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_151 ; owl:annotatedTarget "Discrete, flat or elevated, verrucous, keratotic lesions. Epidermal changes are characterized by acanthosis, parakeratosis, and dyskeratoses. Dysplastic change is present and the keratinocytes vary in size and shape. Associated with UV exposure in humans. Not defined in mice to date."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_591 ; owl:annotatedTarget "Accumulation of mature adipose tissue in a healing wound site or otherwise in response to tissue damage."^^xsd:string . [] oboInOwl:hasDbXref "PMID:15625335"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_592 ; owl:annotatedTarget "Excessive formation of dense trabecular bone and mineralized cartilage, especially in long bones, leading to obliteration of marrow spaces and to anemia with myeloid metaplasia and hepatosplenomegaly beginning in infancy, to bone fragility, and to progressive deafness and blindness."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_592 ; owl:annotatedTarget "Albers-Schoenberg disease"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_592 ; owl:annotatedTarget "marble bone disease"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_592 ; owl:annotatedTarget "marble bones"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_593 ; owl:annotatedTarget "Plasma cell myeloma - (ICD-O 9732/3)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_594 ; owl:annotatedTarget "Formation of multiple retention cysts from obstruction of ducts or glands by hyperplasia of the lining epithelium."^^xsd:string . [] oboInOwl:hasDbXref ":Ward; J.M.; Mann; P.C.; Mrishima; H.; and Frith; C.H. Thymus; Spleen and Lymph nodes. Ch 13. p342. In Maronpot; R. Pathology of the Mouse. (1999) Cache River Press. Vienna IL"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_595 ; owl:annotatedTarget "The formation of and development of blood cells outside the red pulp of the spleen. Composed of varying numbers of megakaryocytes as well as myeloid and erythroid precursors."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_596 ; owl:annotatedTarget "The organic response of tissues to external insult, injury or underlying genetic or epigenetic lesion."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_597 ; owl:annotatedTarget "Processes occurring during cell and tissue damage of either intrinsic or extrinsic etiology."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_152 ; owl:annotatedTarget "Benign proliferation of the basal layer cells of the skin."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_598 ; owl:annotatedTarget "degenerative entity"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_599 ; owl:annotatedTarget "developmental process abnormalities"^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_6 ; owl:annotatedTarget "Necrosis characteristic of some inflammatory conditions which represents necrosis with loss of structure of the various cellular and tissue elements; affected tissue manifests a friable, crumbly consistency."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_60 ; owl:annotatedTarget "Failure of two cavities, voids or lumens to connect."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_600 ; owl:annotatedTarget "Aberrant branch or branching pattern of a branched structure such as the bronchus."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_601 ; owl:annotatedTarget "Increase of the size or cellularity of an organ or tissue as a consequence of loss of normal regulation of cell proliferation."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_602 ; owl:annotatedTarget "An organ or a tissue with an abnormal increase in the number of cells as a consequence of cell proliferation."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_603 ; owl:annotatedTarget "Anatomically located instance of pathological response or entity."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_604 ; owl:annotatedTarget "Abnormal increase or decrease in the rate of cell growth or cell division including associated changes in the differentiation state of adult cells."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_605 ; owl:annotatedTarget "A tissue or group of cells in which there has been abnormal transformation of an fully differentiated adult cell or tissue of one kind into a differentiated tissue of another kind."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_153 ; owl:annotatedTarget "Increased thickness of the granular layer of a stratified squamous epithelium, associated with hyperorthokeratosis."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_606 ; owl:annotatedTarget "The pathological process that results in the formation and growth of a neoplasm."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_606 ; owl:annotatedTarget "neoplastic process"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_607 ; owl:annotatedTarget "Physical entity or structure associated with normal or abnormal tissue healing or repair following extrinsic or intrinsic damage."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_608 ; owl:annotatedTarget "A circumscribed collection of purulent exudate frequently associated with swelling and other signs of inflammation."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_609 ; owl:annotatedTarget "Pus in a body cavity; when used without qualification, refers specifically to pyothorax."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_61 ; owl:annotatedTarget "Inappropriate curvature of a structure."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_610 ; owl:annotatedTarget "Dilatation of a blood vessel or valve."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_611 ; owl:annotatedTarget "Acute or chronic inflammation of the tongue."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_612 ; owl:annotatedTarget "A circumscribed collection of purulent exudate frequently associated with swelling and other signs of inflammation."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_613 ; owl:annotatedTarget "Coloration, either normal or pathologic, of the skin or tissues resulting from a deposit of pigment."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_154 ; owl:annotatedTarget "Thickening of the surface layers (stratum corneum) in the skin or other stratified squamous epithelium. Cf. ortho- and para-keratosis."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_614 ; owl:annotatedTarget "Solid material formed by aggregation of discrete units or particles."^^xsd:string . [] oboInOwl:hasDbXref ":NCI Thesaurus / A7567983"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_615 ; owl:annotatedTarget "A disease of the heart muscle or myocardium proper."^^xsd:string . [] oboInOwl:hasDbXref "Long; P.H.; and Leininger; J.R ( 1999) Bones Joints and synovia; p663. in: Pathology of the Mouse. Ed Maronpot; R. Cache River Press"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_616 ; owl:annotatedTarget "Hypertrophy of bone characterised by an abnormal increase in non-neoplastic skeletal bone mass. These may be proliferative or non-proliferative lesions."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_616 ; owl:annotatedTarget "osteosclerosis"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Mohr"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_617 ; owl:annotatedTarget "Focal lesions of hepatocytes characterised primarily by altered cytoplasmic tinctorial properties. Classified as basophilic, eosinophilic, clear cell or mixed type."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_617 ; owl:annotatedTarget "Areas of cellular alteration"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_617 ; owl:annotatedTarget "Enzyme altered focus"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_617 ; owl:annotatedTarget "Focus of altered hepatocytes (fah)"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_617 ; owl:annotatedTarget "Hyperplastic focus"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_617 ; owl:annotatedTarget "Phenotypically altered focus"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_154 ; owl:annotatedTarget "cornification"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_617 ; owl:annotatedTarget "Preneoplastic focus"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_618 ; owl:annotatedTarget "Hyperplasia of myeloid lineage, usually in the spleen."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_619 ; owl:annotatedTarget "Septal defect lying between the aorta and pulmonary trunks caused by failure of the spiral septum to separate the truncus arteriosus."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_62 ; owl:annotatedTarget "Formation of an epithelium bounded cavity not associated with neoplasia."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_620 ; owl:annotatedTarget "Incomplete closure of the inter-atrial septum due to failure of the primary or secondary septum."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_621 ; owl:annotatedTarget "Failure of the inter-ventricular septum to completely close between the left and right ventricles."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_622 ; owl:annotatedTarget "Abnormal retention of lipids within a cell. Physically apparent as lipid within liposomes of parenchymal cells."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_622 ; owl:annotatedTarget "adipose degeneration"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_622 ; owl:annotatedTarget "fatty change"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_622 ; owl:annotatedTarget "fatty degeneration"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_154 ; owl:annotatedTarget "hyperorthokeratosis"^^xsd:string . [] oboInOwl:hasDbXref "Millodot; Michel and Daniel Laby. Dictionary of Ophthalmology. London: Butterworth Heinemann; 2002"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_623 ; owl:annotatedTarget "An adhesion, usually between the iris and the cornea or the lens capsule."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_624 ; owl:annotatedTarget "Turning in of the edges of a structure."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_625 ; owl:annotatedTarget "Tearing away or separation of two structures or parts."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_626 ; owl:annotatedTarget "To sink down, said of an organ or other part. A sinking of an organ or other part, especially its appearance at a natural or artificial orifice."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_627 ; owl:annotatedTarget "An inflammatory process in which there is infiltration of polymorphonuclear cells into a more chronic area of inflammation characterized by mononuclear cells, macrophages, lymphocytes and possibly plasma cells."^^xsd:string . [] oboInOwl:hasDbXref "Mills; S.E.; Cooper; P.H. & Fechner; R.E. (1980). Lobular capillary hemangioma: the underlying lesion of pyogenic granuloma. A study of 73 cases from the oral and nasal mucous membranes. Am J Surg Pathol; 4; 470-9."^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_628 ; owl:annotatedTarget "A small rounded mass of inflamed, highly vascular granulation tissue on the skin, frequently having an ulcerated surface. More likely a true neoplasm rather than a reactive lesion."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_628 ; owl:annotatedTarget "lobular capillary hemangioma"^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_629 ; owl:annotatedTarget "Deep cutaneous hemangioma with large dilated vascular spaces that manifests spontaneous involution."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_63 ; owl:annotatedTarget "The removal of accumulated fluids or solids."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_630 ; owl:annotatedTarget "Abnormally increased nuclear size."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_154 ; owl:annotatedTarget "hyperparakeratosis"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_631 ; owl:annotatedTarget "Tissue or cells undergoing hypertrophy, MPATH: 159."^^xsd:string . [] oboInOwl:hasDbXref "Journal: Ward; J.M.; Anver; M.R.; Haines; D.C. & Benveniste; R.E. (1994). Chronic active hepatitis in mice caused by Helicobacter hepaticus. Am J Pathol; 145; 959-68."^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_632 ; owl:annotatedTarget "Increase in size of hepatocytes characterised by organelle hyperplasia and enlarged cellular volume."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_633 ; owl:annotatedTarget "Presence of concretions in the gallbladder or bile ducts."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:9780702027888"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_634 ; owl:annotatedTarget "Focal suppurative inflammation of the skin and subcutaneous tissues, enclosing a central slough or `core`."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_634 ; owl:annotatedTarget "Boil"^^xsd:string . [] oboInOwl:hasDbXref "ISBN:9780702027888"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_635 ; owl:annotatedTarget "Swelling of the kidneys when urine flow is obstructed in any of part of the urinary tract. Severe form of pyelectasia."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_636 ; owl:annotatedTarget "Inflammation of fatty tissue."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_637 ; owl:annotatedTarget "A retention cyst, resulting from an obstruction to the duct of a gland, within a bursa."^^xsd:string . [] oboInOwl:hasDbXref "URL:http://cancerweb.ncl.ac.uk/cgi-bin/omd?action=Search+OMD&query=cellulitis"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_638 ; owl:annotatedTarget "An acute, diffuse, spreading, edematous, suppurative inflammation of the deep subcutaneous tissues and sometimes muscle, which may be associated with abscess formation."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_639 ; owl:annotatedTarget "Accumulation of water in the ventricles of the brain."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_155 ; owl:annotatedTarget "Thickening of the anuclear cell layer limited to the stratum corneum, as in a stratified squamous epithelium."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_64 ; owl:annotatedTarget "Abnormal development (of organs or tissues) or an abnormal structure resulting from such growth."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_640 ; owl:annotatedTarget "Deposition of organic bone matrix."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_641 ; owl:annotatedTarget "Intradermal or subcutaneous cyst, the wall of which is stratified epithelium containing keratohyalin granules, surrounding a core of debris."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_642 ; owl:annotatedTarget "Intra or extracellular deposition of cholesterol."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_643 ; owl:annotatedTarget "Non-cellular fluid that filters from the circulatory system and accumulates in lesions or areas of inflammation."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_644 ; owl:annotatedTarget "Accumulation of chitinase-like protein."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_65 ; owl:annotatedTarget "Underdevelopment of an organ due to a decrease in the number of cells through failure to proliferate leading to lack of development."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_652 ; owl:annotatedTarget "Benign proliferation of histiocytes."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_656 ; owl:annotatedTarget "Rupture or disruption of erythrocytes with release of contents."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_66 ; owl:annotatedTarget "Increase in the diameter of an orifice or tubular structure beyond its normal dimensions."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_103 ; owl:annotatedTarget "Any defect in the maternal or embryonic placental circulation."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_156 ; owl:annotatedTarget "Thickening of the surface cell layer of a stratified squamous epithelium with retention of nuclei in the cells of the stratum corneum."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_67 ; owl:annotatedTarget "Abnormal location, orientation, number, loss or non-specified deformity of a structure or tissue."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_670 ; owl:annotatedTarget "A mixed inflammatory cell infiltrate, primarily macrophages and some syncitial cells, around the heart attached to the epicardium."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_68 ; owl:annotatedTarget "A blind ended outpouching through the wall of a tubular organ or bounded cavity."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_69 ; owl:annotatedTarget "ectopia"^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_7 ; owl:annotatedTarget "A type of necrosis in which the affected cells or tissue are reduced to homogeneous eosinophilic mass without nuclear staining, as a result of the protein coagulation, eg. Infarct. Tissue architecture persists."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_70 ; owl:annotatedTarget "An abnormal passage between two internal organs or leading from a cavity to the body surface."^^xsd:string . [] oboInOwl:hasDbXref ":"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_708 ; owl:annotatedTarget "Distension of the renal pelvis by accumulated fluid or urine."^^xsd:string . [] oboInOwl:hasDbXref "ICD-O:8920/3"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_709 ; owl:annotatedTarget "Malignant tumor of striated muscle or pluripotential mesenchymal stem cells composed mainly of small round cells, with some partial skeletal muscle differentiation."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_71 ; owl:annotatedTarget "Failure of two or more structures ( not voids or lumens) to join together."^^xsd:string . [] oboInOwl:hasDbXref "ICD-O:8910/3"^^xsd:string, "ICDO-:8912/3"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_710 ; owl:annotatedTarget "Malignant mesenchymal tumor that morphologically and phenotypically resembles embryonal skeletal muscle."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_157 ; owl:annotatedTarget "Benign hyperplasia and down-growth of epidermal cells. Microscopically resembling well-differentiated squamous cell carcinoma."^^xsd:string . [] oboInOwl:hasDbXref ":"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_718 ; owl:annotatedTarget "Generally benign germ cell derived tumors of male or female containing derivatives from all three germ layers with differentiation in the malignant form being poor. Pre-sacral tumors located in the retrorectal space between the rectum and the sacrococcygeal part of the spine."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_72 ; owl:annotatedTarget "Increase in the rate of growth of an organism, organ or tissue as a consequence of increased proliferation, reduced cell death, or a combination. Not due to an increase in cell size; see Hypertrophy MPATH: 159."^^xsd:string . [] oboInOwl:hasDbXref ":"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_721 ; owl:annotatedTarget "Generally benign germ cell derived tumors of male or female containing derivatives from all three germ layers with differentiation in the malignant form being poor. Sacrococcygeal tumors are located at the base of the coccyx."^^xsd:string . [] oboInOwl:hasDbXref "ICD-O:M-8900/0"^^xsd:string, "PMID:3525381"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_722 ; owl:annotatedTarget "Benign stromal tumors of the soft tissue with skeletal muscle differentiation."^^xsd:string . [] oboInOwl:hasDbXref "ICDO:M-8822/1"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_723 ; owl:annotatedTarget "Systemic manifestation of MPATH: 407."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_724 ; owl:annotatedTarget "Dermal, subcutaneous, or tendinous lesions characterized by accumulations of lipid-laden macrophages often rich in cholesterol."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_73 ; owl:annotatedTarget "The cessation of fetal or embryonic growth beyond a particular stage."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_733 ; owl:annotatedTarget "A uterus distended with a fluid containing large quantities of mucin."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_735 ; owl:annotatedTarget "Thickening of the cementum layer of the molars."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_739 ; owl:annotatedTarget "Extravascular blood between retina and choroid"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_157 ; owl:annotatedTarget "pseudocarcinoma"^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_74 ; owl:annotatedTarget "A focal malformation resembling a neoplasm which results from faulty development of an organ; composed of an abnormal mixture of tissue elements, or an abnormal proportion of a single element. Growth and location are usually normal for that tissue cf. Heterotopia/Choristoma MPATH:76/MPATH:477."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_740 ; owl:annotatedTarget "Tiny yellow or white deposits of lamellar or amorphous extracellular material that build up between retina and retinal pigment epithelium."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_741 ; owl:annotatedTarget "An increase in size of the spleen."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_742 ; owl:annotatedTarget "Rupture of the intervertebral disc, usually dorsally to compress the spinal cord, secondary to trauma."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_743 ; owl:annotatedTarget "Accumulation of clear large vacuoles in hepatocytes (most likely lipid pending frozen sections and oil red O or other lipid stains) around central veins."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_744 ; owl:annotatedTarget "Release of melanin pigment in the dermis."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_745 ; owl:annotatedTarget "Degenerative changes in skeletal muscle including hyalinization, swelling, fragmentation, vacuolation eventually resulting in death of muscle fibers."^^xsd:string . [] oboInOwl:hasDbXref "MPATH::Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_746 ; owl:annotatedTarget "Fragmentation and erosion of articular cartilage."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_747 ; owl:annotatedTarget "Pink amorphous material (amyloid) deposited within the renal tubules."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_748 ; owl:annotatedTarget "An old organized thrombus that has been recanalized to permit blood flow."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_157 ; owl:annotatedTarget "pseudocarcinomatous hyperplasia"^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_749 ; owl:annotatedTarget "Various degrees of pulmonary interstitial fibrosis."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_75 ; owl:annotatedTarget "Protrusion of a loop or wall of an organ through an abnormal opening."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_750 ; owl:annotatedTarget "Neoplastic proliferation of cuboidal cells lining alveoli most likely type II pneumocytes."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_751 ; owl:annotatedTarget "Free pigment in anterior chamber/elsewhere in eye."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_752 ; owl:annotatedTarget "loss of hair resulting from a behavioral abnormality in which the mouse, or more often other mice mice in the same box, remove hairs, initially vibrissae, from each other."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_753 ; owl:annotatedTarget "The forestomach of the mouse is lined by stratified squamous epithelia. At the limiting ridge there is hyperplasia to various degrees in which this epithelium proliferates to form raised areas on thin fibrovascular stalks."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_754 ; owl:annotatedTarget "Spleen contains foci of macrophages containing yellow brown pigment that is positive for iron using Prussian blue."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_755 ; owl:annotatedTarget "Small foci of mineralization within the interstitium between alveoli."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_756 ; owl:annotatedTarget "Chronic inflammation in and around small and medium sized arteries, often in more than one location."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_757 ; owl:annotatedTarget "Foci of mineralization within the interstitium of a tissue."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_157 ; owl:annotatedTarget "pseudoepitheliomatous hyperplasia"^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_758 ; owl:annotatedTarget "Small foci of mineralization within the interstitium between tubules."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_759 ; owl:annotatedTarget "Appearance of clinical and/or subclinical signs and symptoms associated with pregnancy when the animal is not pregnant"^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_76 ; owl:annotatedTarget "Congenital appearance of a body part or tissue or cell type in a region where it is not normally found ( topographical anomaly)."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_76 ; owl:annotatedTarget "Ectopia"^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_760 ; owl:annotatedTarget "Marked dilatation of the ovarian bursa."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_761 ; owl:annotatedTarget "Linear palisaiding of nuclei within thin pale muscle fibers suggestive of repair."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_762 ; owl:annotatedTarget "Thyroid gland follicles are filled with colloid but vary greatly in size."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_763 ; owl:annotatedTarget "Salivary gland duct occlusion resulting in massive enlargement forming a large cyst-like structure."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:PNS"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_764 ; owl:annotatedTarget "A fracture is the (local) separation of a bone into two, or more, pieces under the action of stress."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_765 ; owl:annotatedTarget "Break in bone associated with exostoses."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_158 ; owl:annotatedTarget "Superficial, benign, verrucous, often pigmented, greasy lesions consisting of proliferating epidermal cells, resembling basal cells, enclosing cornifying cysts."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_766 ; owl:annotatedTarget "The lamina propria is distended with amorphous hyalinized material interpreted to be amyloid protein."^^xsd:string . [] oboInOwl:hasDbXref "PMH:0001281"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_767 ; owl:annotatedTarget "A Meckel's diverticulum is a pouch on the wall of the lower part of the intestine that is present at birth."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_768 ; owl:annotatedTarget "Necrosis associated with or caused by local bacterial infection."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_769 ; owl:annotatedTarget "Necrosis of the uterine wall with large bacterial colonies on its surface."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_77 ; owl:annotatedTarget "Stricto sensu: replacement of one body part or tissue by an homologous structure or tissue, but commonly used incorrectly to describe non-homologous transformations better described as heterotopias or ectopias."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:"^^xsd:string, "MPATH:PNS"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_770 ; owl:annotatedTarget "Abnormal organ dimensions or weight"^^xsd:string . [] oboInOwl:hasDbXref "MPATH:"^^xsd:string, "MPATH:PNS"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_771 ; owl:annotatedTarget "Abnormality of extent of the normal long axis"^^xsd:string . [] oboInOwl:hasDbXref "MPATH:"^^xsd:string, "MPATH:PNS"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_772 ; owl:annotatedTarget "Abnormal mass of organ"^^xsd:string . [] oboInOwl:hasDbXref "MPATH:PNS"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_773 ; owl:annotatedTarget "Abnormal length of the intestine."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_774 ; owl:annotatedTarget "Focal necrosis in the liver often but not always associated with thrombosis."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_158 ; owl:annotatedTarget "Basal cell papilloma"^^xsd:string . [] oboInOwl:hasDbXref "MPATH:PNS"^^xsd:string, "mpath:"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_775 ; owl:annotatedTarget "Exertion of abnormal force on a structure or structures usually resulting in deformation and damage."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:PNS"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_776 ; owl:annotatedTarget "A spermatocoele is a cyst that contains spermatozoa. ."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:PNS"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_777 ; owl:annotatedTarget "Formation of urinary concretions in any part of the kidney."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:PNS"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_778 ; owl:annotatedTarget "https://doi.org/10.1038/srep41807"^^xsd:string . [] oboInOwl:hasDbXref "MPATH:PNS"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_779 ; owl:annotatedTarget "Formation or urinary concretions in the ureter."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_78 ; owl:annotatedTarget "Incomplete closure of a void or lumen due to failure of growth or fusion of bounding walls."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:PNS"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_780 ; owl:annotatedTarget "Pseudoxanthoma elasticum is a progressive disorder characterized by accumulated deposits of calcium and other minerals in elastic fibers."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:PNS"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_781 ; owl:annotatedTarget "Softening of brain tissue, usually caused by vascular insufficiency or degenerative changes."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_782 ; owl:annotatedTarget "Collapse of the eye globe associated with degenerative changes."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_783 ; owl:annotatedTarget "Follicular dystrophy, rupture, foreign body reaction, ulceration, scarring, pseudoepitheliomatous hyperplasia are part of a syndrome commonly called B6 dermatitis in black strains of mice."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_158 ; owl:annotatedTarget "seborrheic verruca"^^xsd:string . [] oboInOwl:hasDbXref "MPATH:PNS"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_784 ; owl:annotatedTarget "Degeneration and resorption of an ovarian follicle before it reaches maturity and ruptures."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_785 ; owl:annotatedTarget "Marked production of granulocytes, primarily neutrophils, usually in response to a major acute inflammatory response."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:PNS"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_786 ; owl:annotatedTarget "The drying, thickening and coagulation of extracellular secretions or fluids."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_787 ; owl:annotatedTarget "Ventral prolapse of the intervertebral disk."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_788 ; owl:annotatedTarget "The testicle twisted around the vascular tract to constrict flow resulting in liquifactive necrosis of the affected testicle."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_789 ; owl:annotatedTarget "Dermal granuloma surrounding hair fibers."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_79 ; owl:annotatedTarget "Abnormal position or orientation of a structure insufficient to be called a heterotopia."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_79 ; owl:annotatedTarget "Misplacement"^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_790 ; owl:annotatedTarget "Retinal degeneration of both eyes."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_791 ; owl:annotatedTarget "Occlusion of a vessel by a piece of dissected cartilage."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_159 ; owl:annotatedTarget "Increase in size or mass of a cell, tissue or organ without increase in cell proliferation. Cf. Hyperplasia MPATH: 133."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_792 ; owl:annotatedTarget "Proliferation of the reticuloendothelial cells in the medulla of the lymph node."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_793 ; owl:annotatedTarget "An increase in the size of the spleen due to ongoing acute or chronic infection."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_794 ; owl:annotatedTarget "Digested blood in the lumen of the stomach or small intestine, indicative of hemorrhage."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_795 ; owl:annotatedTarget "Round , often laminar, non-proteinaceous eosinophilic bodies representing calcium deposition."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_796 ; owl:annotatedTarget "Lack of sperm."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:PNS"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_797 ; owl:annotatedTarget "Compromise or abnormality of the process of spermatogenesis"^^xsd:string . [] oboInOwl:hasDbXref "MPATH:PNS"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_798 ; owl:annotatedTarget "Reduced numbers of sperm."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_799 ; owl:annotatedTarget "scoliosis is an abnormal curvature of the spine. The spine curves away from the middle or sideways."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0781727286"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_8 ; owl:annotatedTarget "Dead and dying adipose tissue, characterized by the formation of small gray or white foci of soapy (saponified) cellular debris."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Pathology Committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_80 ; owl:annotatedTarget "Occlusion ( partial or complete) of a lumen or space, internally by a space occupying mass or, in the case of stenosis, by local reduction in the diameter of a vessel, duct or the intestine."^^xsd:string . [] oboInOwl:hasDbXref "Pathbase: Curation"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty oboInOwl:hasRelatedSynonym ; owl:annotatedSource obo:MPATH_16 ; owl:annotatedTarget "Mucoid degeneration"^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_800 ; owl:annotatedTarget "Dorsal prolapse of the intervertebral disk."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_801 ; owl:annotatedTarget "Presence of dorsal and ventrally prolapsed disks in the same vertebral column."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_802 ; owl:annotatedTarget "Eversion through the anus."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Sundberg"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_803 ; owl:annotatedTarget "Thickening of trabecular bone."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0-19-261976-4"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_804 ; owl:annotatedTarget "Large numbers of thin-walled dilated lymphatic channels situated in the dermis, subcutis or skeletal muscle."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0-19-261976-4"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_805 ; owl:annotatedTarget "Variant of cavernous lymphangioma (MPATH:804) showing gross dilatation of lymphatic channels."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0-19-261976-4"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_806 ; owl:annotatedTarget "Cutaneous grouped collection of thin-walled translucent vessels, which appear at birth or in early infancy and are commonest around the limb girdles."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0-19-261976-4"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_807 ; owl:annotatedTarget "Large cystic subcutaneous spaces usually found in the flexures, especially around the neck."^^xsd:string . [] oboInOwl:hasDbXref "ISBN:0-19-261976-4"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_808 ; owl:annotatedTarget "Accumulation of interstitial fluid caused by blockage or failure of the lymphatic system."^^xsd:string . [] oboInOwl:hasDbXref "MPATH:Pathology committee"^^xsd:string ; a owl:Axiom ; owl:annotatedProperty obo:IAO_0000115 ; owl:annotatedSource obo:MPATH_809 ; owl:annotatedTarget "Edema of the posterior aspect of the fetal neck caused by an accumulation of fluid, usually lymph."^^xsd:string .